메뉴 건너뛰기




Volumn 2, Issue 6, 2010, Pages

The generation and properties of human M2-like macrophages: Potential candidates for CNS repair?

Author keywords

Chemokines; CNS repair; Cytokines; Growth factors; Macrophage polarization

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CD86 ANTIGEN; COLONY STIMULATING FACTOR 1; EPIDERMAL GROWTH FACTOR; ERYTHROPOIETIN; FIBROBLAST GROWTH FACTOR 2; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; SOMATOMEDIN C; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

EID: 84856827114     PISSN: 1867416X     EISSN: 18668836     Source Type: Journal    
DOI: 10.3205/ctt-2010-en-000080.01     Document Type: Article
Times cited : (31)

References (38)
  • 1
    • 0034964683 scopus 로고    scopus 로고
    • Effects of basic fbroblast growth factor on central nervous system functions
    • Abe, K. Effects of basic fbroblast growth factor on central nervous system functions. Pharmacol Res. 2001;43:307-302.
    • (2001) Pharmacol Res , vol.43 , pp. 302-307
    • Abe, K.1
  • 2
    • 77649147710 scopus 로고    scopus 로고
    • Effect of locally delivered IGF-1 on nerve regeneration during aging: An experimental study in rats
    • doi: 10.1002/mus.21485, Oct
    • Apel PJ, Ma J, Callahan M, Northam CN, Alton TB, Sonntag WE, Li Z. Effect of locally delivered IGF-1 on nerve regeneration during aging: an experimental study in rats. Muscle Nerve. 2009 Oct. 2. doi: 10.1002/mus.21485.
    • (2009) Muscle Nerve , pp. 2
    • Apel, P.J.1    Ma, J.2    Callahan, M.3    Northam, C.N.4    Alton, T.B.5    Sonntag, W.E.6    Li, Z.7
  • 3
    • 0642309623 scopus 로고    scopus 로고
    • Features of skin-coincubated macrophages that promote recovery from spinal cord injury
    • doi: 10.1016/S0165-5728(03)00260-1
    • Bomstein Y, Marder JB, Vitner K, Smirnov I, Lisaey G, Butovs-ky O, Fulga V, Yoles E. Features of skin-coincubated macrophages that promote recovery from spinal cord injury. J Neuroimmunol. 2003;142:10-16. doi: 10.1016/S0165-5728(03)00260-1.
    • (2003) J Neuroimmunol , vol.142 , pp. 10-16
    • Bomstein, Y.1    Marder, J.B.2    Vitner, K.3    Smirnov, I.4    Lisaey, G.5    Butovs-Ky, O.6    Fulga, V.7    Yoles, E.8
  • 4
    • 0038348541 scopus 로고    scopus 로고
    • Brain repair and neuroprotection by serum insulin-like growth factor-I
    • doi: 10.1385/MN:27:2:153
    • Carro E, Trejo JL, Núñez, A, Torres-Aleman I. Brain repair and neuroprotection by serum insulin-like growth factor-I. Mol Neuro-biol. 2003;27:153-162. doi: 10.1385/MN:27:2:153.
    • (2003) Mol Neuro-biol , vol.27 , pp. 153-162
    • Carro, E.1    Trejo, J.L.2    Núñez, A.3    Torres-Aleman, I.4
  • 5
    • 12744260011 scopus 로고    scopus 로고
    • The neuroprotective role of infammation in nervous system injuries
    • doi: 10.1007/s00415-004-0649-z
    • Correale J, Villa A. The neuroprotective role of infammation in nervous system injuries. J Neurol. 2004;251:1304-1316. doi: 10.1007/s00415-004-0649-z.
    • (2004) J Neurol , vol.251 , pp. 1304-1316
    • Correale, J.1    Villa, A.2
  • 6
    • 38749086493 scopus 로고    scopus 로고
    • Infammation and its role in neuro-protection, axonal regeneration and functional recovery after spinal cord injury
    • doi: 10.1016/j.expneu-rol.2007.06.009
    • Donnelly DJ, Popovich PG. Infammation and its role in neuro-protection, axonal regeneration and functional recovery after spinal cord injury. Exp Neurol. 2008;209:378-388. doi: 10.1016/j.expneu-rol.2007.06.009.
    • (2008) Exp Neurol , vol.209 , pp. 378-388
    • Donnelly, D.J.1    Popovich, P.G.2
  • 7
    • 0029972857 scopus 로고    scopus 로고
    • Brain microglia/ma-crophages express neurotrophins that selectively regulate microglial proliferation and function
    • pmid: 8786427
    • Elkabes S, Dicicco-Bloom EM, Black IB. Brain microglia/ma-crophages express neurotrophins that selectively regulate microglial proliferation and function. J Neurosci. 1996;16:2508-2521. pmid: 8786427.
    • (1996) J Neurosci , vol.16 , pp. 2508-2521
    • Elkabes, S.1    Dicicco-Bloom, E.M.2    Black, I.B.3
  • 8
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinfammatory cytokine production through autocrine/parac-rine mechanisms involving TGF-beta, PGE2, and PAF
    • doi: 10.1172/JCI1112
    • Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Hen-son PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinfammatory cytokine production through autocrine/parac-rine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest. 1998;101:890-898. doi: 10.1172/JCI1112.
    • (1998) J Clin Invest , vol.101 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Hen-Son, P.M.6
  • 9
    • 0031426869 scopus 로고    scopus 로고
    • Activated macrophages and the blood-brain barrier: Infammation after CNS injury leads to increases in putative inhibitory molecules
    • doi: 10.1006/exnr.1997.6701
    • Fitch MT, Silver J. Activated macrophages and the blood-brain barrier: infammation after CNS injury leads to increases in putative inhibitory molecules. Exp Neurol. 1997;148:587-603. doi: 10.1006/exnr.1997.6701.
    • (1997) Exp Neurol , vol.148 , pp. 587-603
    • Fitch, M.T.1    Silver, J.2
  • 10
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • doi:10.1038/nri978
    • Gordon, S. Alternative activation of macrophages. Nat Rev Immunol. 2003;3:23-35. doi:10.1038/nri978.
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 11
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • doi: 10.1038/nri1733
    • Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 2005;5:953-964. doi: 10.1038/nri1733.
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 12
    • 34249804796 scopus 로고    scopus 로고
    • Dual role of infamma-tion in CNS disease
    • pmid: 17548571
    • Hohlfeld R, Kerschensteiner M, Meinl E. Dual role of infamma-tion in CNS disease. Neurology. 2007;68(3):58-63. pmid: 17548571.
    • (2007) Neurology , vol.68 , Issue.3 , pp. 58-63
    • Hohlfeld, R.1    Kerschensteiner, M.2    Meinl, E.3
  • 14
    • 70350558453 scopus 로고    scopus 로고
    • Identifcation of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord
    • doi: 10.1523/JNEUROSCI.3257-09.2009
    • Kigerl KA, Gensel JC, Ankeny DP, Alexander JK, Donnelly DJ, Popovich PG. Identifcation of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. J. Neurosci. 2009;29:13435-13444. doi: 10.1523/JNEUROSCI.3257-09.2009.
    • (2009) J. Neurosci , vol.29 , pp. 13435-13444
    • Kigerl, K.A.1    Gensel, J.C.2    Ankeny, D.P.3    Alexander, J.K.4    Donnelly, D.J.5    Popovich, P.G.6
  • 15
    • 34247252525 scopus 로고    scopus 로고
    • Erythropoietin is both neuroprotective and neuroregenerative following optic nerve transaction
    • King C.E, Rodger J, Bartlett C, Esmaili T, Dunlop SA, Beazley LD. Erythropoietin is both neuroprotective and neuroregenerative following optic nerve transaction. Exp Neurol. 2007;205:48-55.
    • (2007) Exp Neurol , vol.205 , pp. 48-55
    • King, C.E.1    Rodger, J.2    Bartlett, C.3    Esmaili, T.4    Dunlop, S.A.5    Beazley, L.D.6
  • 17
    • 0033935962 scopus 로고    scopus 로고
    • The macrophage in acute neural injury: Changes in cell numbers over time and levels of cytokine production in mammalian central and peripheral nervous systems
    • Leskovar A, Moriarty LJ, Turek JJ, Schoenlein IA, Borgens RB. The macrophage in acute neural injury: changes in cell numbers over time and levels of cytokine production in mammalian central and peripheral nervous systems. J Exp Biol. 2000;203:1783-1795.
    • (2000) J Exp Biol , vol.203 , pp. 1783-1795
    • Leskovar, A.1    Moriarty, L.J.2    Turek, J.J.3    Schoenlein, I.A.4    Borgens, R.B.5
  • 18
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • doi:10.1016/j. it.2004.09.015
    • Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 2004;25:677-686. doi:10.1016/j. it.2004.09.015.
    • (2004) Trends Immunol , vol.25 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 19
    • 4944244477 scopus 로고    scopus 로고
    • The contribution of activated phagocytes and myelin degeneration to axonal retraction/dieback following spinal cord injury
    • doi: 10.1111/j.1460-9568.2004.03662.x
    • McPhail LT, Stirling DP, Tetzlaff W, Kwiecien JM, Ramer MS. The contribution of activated phagocytes and myelin degeneration to axonal retraction/dieback following spinal cord injury. Eur J Neu-rosci. 2004;20:1984-1994. doi: 10.1111/j.1460-9568.2004.03662.x.
    • (2004) Eur J Neu-rosci , vol.20 , pp. 1984-1994
    • McPhail, L.T.1    Stirling, D.P.2    Tetzlaff, W.3    Kwiecien, J.M.4    Ramer, M.S.5
  • 20
    • 0037310024 scopus 로고    scopus 로고
    • The many faces of macrophage activation
    • Mosser DM. The many faces of macrophage activation. J Leukocyte Biol. 2003;73:209-212.
    • (2003) J Leukocyte Biol , vol.73 , pp. 209-212
    • Mosser, D.M.1
  • 21
    • 67651172779 scopus 로고    scopus 로고
    • Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1beta release through pyrophos-phates
    • doi: 10.1038/emboj.2009.163
    • Pelegrin P, Surprenant A. Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1beta release through pyrophos-phates. EMBO J. 2009;28:2114-2127. doi: 10.1038/emboj.2009.163.
    • (2009) EMBO J , vol.28 , pp. 2114-2127
    • Pelegrin, P.1    Surprenant, A.2
  • 22
    • 0035283010 scopus 로고    scopus 로고
    • Low serum conditions for in vitro generation of human macrophages with macrophage colony stimulating factor
    • Plesner A, Greenbaumb CJ, Lernmarka A. Low serum conditions for in vitro generation of human macrophages with macrophage colony stimulating factor. J Immunol Meth. 2001;249:53-61.
    • (2001) J Immunol Meth , vol.249 , pp. 53-61
    • Plesner, A.1    Greenbaumb, C.J.2    Lernmarka, A.3
  • 23
    • 0031427380 scopus 로고    scopus 로고
    • Activated ma-crophage/microglial cells can promote the regeneration of sensory axons into the injured spinal cord
    • doi:10.1006/exnr.1997.6694
    • Prewitt CM, Niesman IR, Kane CJ, Houle JD. Activated ma-crophage/microglial cells can promote the regeneration of sensory axons into the injured spinal cord. Exp Neurol. 1997;148:433-443. doi:10.1006/exnr.1997.6694.
    • (1997) Exp Neurol , vol.148 , pp. 433-443
    • Prewitt, C.M.1    Niesman, I.R.2    Kane, C.J.3    Houle, J.D.4
  • 24
    • 0031022698 scopus 로고    scopus 로고
    • Grafting of cultured microglial cells into the lesioned spinal cord of adult rats enhances neurite out growth
    • doi: 10.1002/(SICI)1097- 4547(19970101)47:1<34::AID-JNR4>3.0.CO;2-G
    • Rabchevsky AG, Streit WJ. Grafting of cultured microglial cells into the lesioned spinal cord of adult rats enhances neurite out growth. J Neurosci Res. 1997;47:34-48 doi: 10.1002/(SICI)1097- 4547(19970101)47:1<34::AID-JNR4>3.0.CO;2-G
    • (1997) J Neurosci Res , vol.47 , pp. 34-48
    • Rabchevsky, A.G.1    Streit, W.J.2
  • 27
    • 0032907709 scopus 로고    scopus 로고
    • Potential repair of rat spinal cord injuries using stimulated homologous macrophages
    • pmid: 10232537
    • Schwartz M, Lazarov-Spiegler O, Rapalino O, Agranov I, Velan G, Hadani M. Potential repair of rat spinal cord injuries using stimulated homologous macrophages. Neurosurgery. 1999;44:1041-1045. pmid: 10232537.
    • (1999) Neurosurgery , vol.44 , pp. 1041-1045
    • Schwartz, M.1    Lazarov-Spiegler, O.2    Rapalino, O.3    Agranov, I.4    Velan, G.5    Hadani, M.6
  • 29
    • 84993790552 scopus 로고    scopus 로고
    • Recombinant human ery-thropoietin: Novel strategies for neuroprotective/neuroregenerative treatment of multiple sclerosis
    • Spate CK, Krampe H, Ehrenreich H. Recombinant human ery-thropoietin: novel strategies for neuroprotective/neuroregenerative treatment of multiple sclerosis. Therapeutic Advances in Neurological Disorders. 2008;1:193-206.
    • (2008) Therapeutic Advances In Neurological Disorders , vol.1 , pp. 193-206
    • Spate, C.K.1    Krampe, H.2    Ehrenreich, H.3
  • 30
    • 0036935538 scopus 로고    scopus 로고
    • Detrimental and benefcial effects of injury-induced infammation and cytokine expression in the nervous system
    • pmid: 12575818
    • Stoll G, Jander S, Schroeter M. Detrimental and benefcial effects of injury-induced infammation and cytokine expression in the nervous system. Adv Exp Med Biol. 2002;513:87-113. pmid: 12575818.
    • (2002) Adv Exp Med Biol , vol.513 , pp. 87-113
    • Stoll, G.1    Jander, S.2    Schroeter, M.3
  • 31
    • 85047694286 scopus 로고    scopus 로고
    • VEGF: A critical player in neurode-generation
    • doi: 10.1172/JCI20682
    • Storkebaum E, Carmeliet P. VEGF: a critical player in neurode-generation. J Clin Invest. 2004;113:14-18. doi: 10.1172/JCI20682.
    • (2004) J Clin Invest , vol.113 , pp. 14-18
    • Storkebaum, E.1    Carmeliet, P.2
  • 32
    • 21244443731 scopus 로고    scopus 로고
    • Macrophages sequentially change their functional phenotype in response to changes in microenvironmental infuences
    • Stout RD, Jiang C, Matta B, Tietzel I, Watkins SK, Suttles J. Macrophages sequentially change their functional phenotype in response to changes in microenvironmental infuences. J Immunol. 2005;175:342-349.
    • (2005) J Immunol , vol.175 , pp. 342-349
    • Stout, R.D.1    Jiang, C.2    Matta, B.3    Tietzel, I.4    Watkins, S.K.5    Suttles, J.6
  • 33
    • 33847043183 scopus 로고    scopus 로고
    • Molecular and cellular immune mediators of neuroprotection
    • doi: 10.1385/MN:34:3:221
    • Turrin NP, Rivest S. Molecular and cellular immune mediators of neuroprotection. Molecular Neurobiology. 2006;34:221-242. doi: 10.1385/MN:34:3:221.
    • (2006) Molecular Neurobiology , vol.34 , pp. 221-242
    • Turrin, N.P.1    Rivest, S.2
  • 35
    • 33646455658 scopus 로고    scopus 로고
    • Phenotypic and functional profling of human pro-infammatory type-1 and anti-infammatory type-2 macrophages in response to microbial antigens and IFN- - and CD40L-mediated costimulation
    • doi:10.1189/ jlb.0105015
    • Verreck FA, de Boer T, Langenberg DM, van der Zanden L, Ottenhoff TH. Phenotypic and functional profling of human pro-infammatory type-1 and anti-infammatory type-2 macrophages in response to microbial antigens and IFN- - and CD40L-mediated costimulation. J. Leukocyte Biol. 2006;79:285-293. doi:10.1189/ jlb.0105015.
    • (2006) J. Leukocyte Biol , vol.79 , pp. 285-293
    • Verreck, F.A.1    de Boer, T.2    Langenberg, D.M.3    van der Zanden, L.4    Ottenhoff, T.H.5
  • 36
    • 1942541169 scopus 로고    scopus 로고
    • The role of epidermal growth factor and its receptors in mammalian CNS
    • Wing R, Wong C, Guillaud L. The role of epidermal growth factor and its receptors in mammalian CNS. Cytokines & Growth factors. 2004;15:147-156.
    • (2004) Cytokines & Growth Factors , vol.15 , pp. 147-156
    • Wing, R.1    Wong, C.2    Guillaud, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.