A novel neuroprotective therapy for Parkinson's disease using a viral noncoding RNA that protects mitochondrial Complex I activity

Journal of Experimental Medicine

Volumn 209, Issue 1, 2012, Pages 1-10

  Kuan, Wei Li ^a,b   Poole, Emma ^a   Fletcher, Michael ^a   Karniely, Sharon ^a   Tyers, Pam ^a,b   Wills, Mark ^a   Barker, Roger A ^a,b   Sinclair, John H ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; NEUROPROTECTIVE AGENT; P137 RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG; UNTRANSLATED RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MALE; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT;

ANIMALS; CELL DEATH; CELL LINE; CYTOMEGALOVIRUS; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; ELECTRON TRANSPORT COMPLEX I; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; NEUROTOXINS; PARKINSON DISEASE; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RNA TRANSPORT; RNA, UNTRANSLATED; RNA, VIRAL; SUBSTANTIA NIGRA;

EID: 84856817318     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20111126     Document Type: Article

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