메뉴 건너뛰기




Volumn 7, Issue 2, 2012, Pages

Immunization against Leishmania major infection using LACK- and IL-12-expressing lactococcus lactis induces delay in footpad swelling

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; INTERLEUKIN 12; PROTEIN LACK; UNCLASSIFIED DRUG; LACK ANTIGEN, LEISHMANIA; PARASITE ANTIGEN; PROTOZOAL PROTEIN;

EID: 84856770193     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030945     Document Type: Article
Times cited : (28)

References (46)
  • 1
    • 77956707753 scopus 로고    scopus 로고
    • Cutaneous leishmaniasis: advances in disease pathogenesis, diagnostics and therapeutics
    • Ameen M, (2010) Cutaneous leishmaniasis: advances in disease pathogenesis, diagnostics and therapeutics. Clin Exp Dermatol 35: 699-705.
    • (2010) Clin Exp Dermatol , vol.35 , pp. 699-705
    • Ameen, M.1
  • 3
    • 0036831673 scopus 로고    scopus 로고
    • The immunology of susceptibility and resistance to Leishmania major in mice
    • Sacks D, Noben-Trauth N, (2002) The immunology of susceptibility and resistance to Leishmania major in mice. Nat Rev Immunol 2: 845-858.
    • (2002) Nat Rev Immunol , vol.2 , pp. 845-858
    • Sacks, D.1    Noben-Trauth, N.2
  • 4
    • 79951919391 scopus 로고    scopus 로고
    • Cell biology and immunology of Leishmania
    • Mougneau E, Bihl F, Glaichenhaus N, (2011) Cell biology and immunology of Leishmania. Immunol Rev 240: 286-296.
    • (2011) Immunol Rev , vol.240 , pp. 286-296
    • Mougneau, E.1    Bihl, F.2    Glaichenhaus, N.3
  • 5
    • 0037090268 scopus 로고    scopus 로고
    • CD8+ T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major
    • Belkaid Y, von Stebut E, Mendez S, Lira R, Caler E, et al. (2002) CD8+ T cells are required for primary immunity in C57BL/6 mice following low-dose, intradermal challenge with Leishmania major. J Immunol 168: 3992-4000.
    • (2002) J Immunol , vol.168 , pp. 3992-4000
    • Belkaid, Y.1    von Stebut, E.2    Mendez, S.3    Lira, R.4    Caler, E.5
  • 6
    • 0027255488 scopus 로고
    • Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice
    • Scharton TM, Scott P, (1993) Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice. J Exp Med 178: 567-577.
    • (1993) J Exp Med , vol.178 , pp. 567-577
    • Scharton, T.M.1    Scott, P.2
  • 7
    • 77954990444 scopus 로고    scopus 로고
    • Leishmaniasis Vaccine: Where are We Today?
    • Kedzierski L, (2010) Leishmaniasis Vaccine: Where are We Today? J Glob Infect Dis 2: 177-185.
    • (2010) J Glob Infect Dis , vol.2 , pp. 177-185
    • Kedzierski, L.1
  • 8
    • 0029030456 scopus 로고
    • Expression cloning of a protective Leishmania antigen
    • Mougneau E, Altare F, Wakil AE, Zheng S, Coppola T, et al. (1995) Expression cloning of a protective Leishmania antigen. Science 268: 563-566.
    • (1995) Science , vol.268 , pp. 563-566
    • Mougneau, E.1    Altare, F.2    Wakil, A.E.3    Zheng, S.4    Coppola, T.5
  • 9
    • 0344305409 scopus 로고    scopus 로고
    • Leishmania major LACK antigen is required for efficient vertebrate parasitization
    • Kelly BL, Stetson DB, Locksley RM, (2003) Leishmania major LACK antigen is required for efficient vertebrate parasitization. J Exp Med 198: 1689-1698.
    • (2003) J Exp Med , vol.198 , pp. 1689-1698
    • Kelly, B.L.1    Stetson, D.B.2    Locksley, R.M.3
  • 10
    • 0033083167 scopus 로고    scopus 로고
    • Molecular cloning, cell localization and binding affinity to DNA replication proteins of the p36/LACK protective antigen from Leishmania infantum
    • Gonzalez-Aseguinolaza G, Taladriz S, Marquet A, Larraga V, (1999) Molecular cloning, cell localization and binding affinity to DNA replication proteins of the p36/LACK protective antigen from Leishmania infantum. Eur J Biochem 259: 909-916.
    • (1999) Eur J Biochem , vol.259 , pp. 909-916
    • Gonzalez-Aseguinolaza, G.1    Taladriz, S.2    Marquet, A.3    Larraga, V.4
  • 11
    • 0034910319 scopus 로고    scopus 로고
    • Protective immune response against cutaneous leishmaniasis by prime/booster immunization regimens with vaccinia virus recombinants expressing Leishmania infantum p36/LACK and IL-12 in combination with purified p36
    • Gonzalo RM, Rodriguez JR, Rodriguez D, Gonzalez-Aseguinolaza G, Larraga, et al. (2001) Protective immune response against cutaneous leishmaniasis by prime/booster immunization regimens with vaccinia virus recombinants expressing Leishmania infantum p36/LACK and IL-12 in combination with purified p36. Microbes Infect 3: 701-711.
    • (2001) Microbes Infect , vol.3 , pp. 701-711
    • Gonzalo, R.M.1    Rodriguez, J.R.2    Rodriguez, D.3    Gonzalez-Aseguinolaza, G.4    Larraga5
  • 12
    • 23344439229 scopus 로고    scopus 로고
    • Heterologous prime-boost vaccination with the LACK antigen protects against murine visceral leishmaniasis
    • Dondji B, Perez-Jimenez E, Goldsmith-Pestana K, Esteban M, McMahon-Pratt D, (2005) Heterologous prime-boost vaccination with the LACK antigen protects against murine visceral leishmaniasis. Infect Immun 73: 5286-5289.
    • (2005) Infect Immun , vol.73 , pp. 5286-5289
    • Dondji, B.1    Perez-Jimenez, E.2    Goldsmith-Pestana, K.3    Esteban, M.4    McMahon-Pratt, D.5
  • 13
    • 0037295526 scopus 로고    scopus 로고
    • The combination of DNA vectors expressing IL-12 + IL-18 elicits high protective immune response against cutaneous leishmaniasis after priming with DNA-p36/LACK and the cytokines, followed by a booster with a vaccinia virus recombinant expressing p36/LACK
    • Tapia E, Perez-Jimenez E, Lopez-Fuertes L, Gonzalo R, Gherardi MM, et al. (2003) The combination of DNA vectors expressing IL-12 + IL-18 elicits high protective immune response against cutaneous leishmaniasis after priming with DNA-p36/LACK and the cytokines, followed by a booster with a vaccinia virus recombinant expressing p36/LACK. Microbes Infect 5: 73-84.
    • (2003) Microbes Infect , vol.5 , pp. 73-84
    • Tapia, E.1    Perez-Jimenez, E.2    Lopez-Fuertes, L.3    Gonzalo, R.4    Gherardi, M.M.5
  • 14
    • 3342986328 scopus 로고    scopus 로고
    • Intranasal vaccination against cutaneous leishmaniasis with a particulated leishmanial antigen or DNA encoding LACK
    • Pinto EF, Pinheiro RO, Rayol A, Larraga V, Rossi-Bergmann B, (2004) Intranasal vaccination against cutaneous leishmaniasis with a particulated leishmanial antigen or DNA encoding LACK. Infect Immun 72: 4521-4527.
    • (2004) Infect Immun , vol.72 , pp. 4521-4527
    • Pinto, E.F.1    Pinheiro, R.O.2    Rayol, A.3    Larraga, V.4    Rossi-Bergmann, B.5
  • 15
    • 0033961616 scopus 로고    scopus 로고
    • Listeria monocytogenes as a short-lived delivery system for the induction of type 1 cell-mediated immunity against the p36/LACK antigen of Leishmania major
    • Soussi N, Milon G, Colle JH, Mougneau E, Glaichenhaus N, et al. (2000) Listeria monocytogenes as a short-lived delivery system for the induction of type 1 cell-mediated immunity against the p36/LACK antigen of Leishmania major. Infect Immun 68: 1498-1506.
    • (2000) Infect Immun , vol.68 , pp. 1498-1506
    • Soussi, N.1    Milon, G.2    Colle, J.H.3    Mougneau, E.4    Glaichenhaus, N.5
  • 16
    • 0037150472 scopus 로고    scopus 로고
    • Effect of intragastric and intraperitoneal immunisation with attenuated and wild-type LACK-expressing Listeria monocytogenes on control of murine Leishmania major infection
    • Soussi N, Saklani-Jusforgues H, Colle JH, Milon G, Glaichenhaus N, et al. (2002) Effect of intragastric and intraperitoneal immunisation with attenuated and wild-type LACK-expressing Listeria monocytogenes on control of murine Leishmania major infection. Vaccine 20: 2702-2712.
    • (2002) Vaccine , vol.20 , pp. 2702-2712
    • Soussi, N.1    Saklani-Jusforgues, H.2    Colle, J.H.3    Milon, G.4    Glaichenhaus, N.5
  • 17
    • 3342965738 scopus 로고    scopus 로고
    • DNA-Salmonella enterica serovar Typhimurium primer-booster vaccination biases towards T helper 1 responses and enhances protection against Leishmania major infection in mice
    • Lange UG, Mastroeni P, Blackwell JM, Stober CB, (2004) DNA-Salmonella enterica serovar Typhimurium primer-booster vaccination biases towards T helper 1 responses and enhances protection against Leishmania major infection in mice. Infect Immun 72: 4924-4928.
    • (2004) Infect Immun , vol.72 , pp. 4924-4928
    • Lange, U.G.1    Mastroeni, P.2    Blackwell, J.M.3    Stober, C.B.4
  • 18
    • 50049088779 scopus 로고    scopus 로고
    • Safety assessment of dairy microorganisms: the Lactococcus genus
    • Casalta E, Montel MC, (2008) Safety assessment of dairy microorganisms: the Lactococcus genus. Int J Food Microbiol 126: 271-273.
    • (2008) Int J Food Microbiol , vol.126 , pp. 271-273
    • Casalta, E.1    Montel, M.C.2
  • 19
    • 80051773342 scopus 로고
    • US FDA [21CFR184.1985]. U.S. Food and Drug Administration: Code of Federal Regulations, Title 21 - Food and Drugs; Chapter I - Food and Drug Administration, Department of Health and Human Services; Subchapter B - Food for human consumption; Part 184 - Direct food substances affirmed as Generally Recognized as Safe
    • US FDA, (1995) Aminopeptidase enzyme preparation derived from Lactococcus lactis. [21CFR184.1985]. U.S. Food and Drug Administration: Code of Federal Regulations, Title 21- Food and Drugs; Chapter I- Food and Drug Administration, Department of Health and Human Services; Subchapter B- Food for human consumption; Part 184- Direct food substances affirmed as Generally Recognized as Safe.
    • (1995) Aminopeptidase enzyme preparation derived from Lactococcus lactis
  • 20
    • 77950845407 scopus 로고    scopus 로고
    • Lactococcus lactis as a cell factory for delivery of therapeutic proteins
    • Bahey-El-Din M, Gahan CG, Griffin BT, (2010) Lactococcus lactis as a cell factory for delivery of therapeutic proteins. Curr Gene Ther 10: 34-45.
    • (2010) Curr Gene Ther , vol.10 , pp. 34-45
    • Bahey-El-Din, M.1    Gahan, C.G.2    Griffin, B.T.3
  • 21
    • 0037055969 scopus 로고    scopus 로고
    • Protection against tetanus toxin after intragastric administration of two recombinant lactic acid bacteria: impact of strain viability and in vivo persistence
    • Grangette C, Muller-Alouf H, Geoffroy M, Goudercourt D, Turneer M, et al. (2002) Protection against tetanus toxin after intragastric administration of two recombinant lactic acid bacteria: impact of strain viability and in vivo persistence. Vaccine 20: 3304-3309.
    • (2002) Vaccine , vol.20 , pp. 3304-3309
    • Grangette, C.1    Muller-Alouf, H.2    Geoffroy, M.3    Goudercourt, D.4    Turneer, M.5
  • 23
    • 2142662154 scopus 로고    scopus 로고
    • Mucosal and cellular immune responses elicited by recombinant Lactococcus lactis strains expressing tetanus toxin fragment C
    • Robinson K, Chamberlain LM, Lopez MC, Rush CM, Marcotte H, et al. (2004) Mucosal and cellular immune responses elicited by recombinant Lactococcus lactis strains expressing tetanus toxin fragment C. Infection & Immunity 72: 2753-2761.
    • (2004) Infection & Immunity , vol.72 , pp. 2753-2761
    • Robinson, K.1    Chamberlain, L.M.2    Lopez, M.C.3    Rush, C.M.4    Marcotte, H.5
  • 24
    • 42349105761 scopus 로고    scopus 로고
    • Mucosal delivery of therapeutic and prophylactic molecules using lactic acid bacteria
    • Wells JM, Mercenier A, (2008) Mucosal delivery of therapeutic and prophylactic molecules using lactic acid bacteria. Nat Rev Microbiol 6: 349-362.
    • (2008) Nat Rev Microbiol , vol.6 , pp. 349-362
    • Wells, J.M.1    Mercenier, A.2
  • 25
    • 71449127101 scopus 로고    scopus 로고
    • Modulation of gut-associated lymphoid tissue functions with genetically modified Lactococcus lactis
    • Rottiers P, De Smedt T, Steidler L, (2009) Modulation of gut-associated lymphoid tissue functions with genetically modified Lactococcus lactis. Int Rev Immunol 28: 465-486.
    • (2009) Int Rev Immunol , vol.28 , pp. 465-486
    • Rottiers, P.1    De Smedt, T.2    Steidler, L.3
  • 27
    • 79851470191 scopus 로고    scopus 로고
    • Targeting diseases with genetically engineered Lactococcus lactis and its course towards medical translation
    • Villatoro-Hernandez J, Montes-de-Oca-Luna R, Kuipers OP, (2011) Targeting diseases with genetically engineered Lactococcus lactis and its course towards medical translation. Expert Opin Biol Ther.
    • (2011) Expert Opin Biol Ther
    • Villatoro-Hernandez, J.1    Montes-de-Oca-Luna, R.2    Kuipers, O.P.3
  • 28
    • 43049161297 scopus 로고    scopus 로고
    • Innate inflammatory responses to the Gram-positive bacterium Lactococcus lactis
    • Yam KK, Pouliot P, N'diaye MM, Fournier S, Olivier M, et al. (2008) Innate inflammatory responses to the Gram-positive bacterium Lactococcus lactis. Vaccine 26: 2689-2699.
    • (2008) Vaccine , vol.26 , pp. 2689-2699
    • Yam, K.K.1    Pouliot, P.2    N'diaye, M.M.3    Fournier, S.4    Olivier, M.5
  • 29
    • 80051744665 scopus 로고    scopus 로고
    • Generation and evaluation of A2-expressing Lactococcus lactis live vaccines against Leishmania donovani in BALB/c mice
    • Yam KK, Hugentobler F, Pouliot P, Stern AM, Lalande JD, et al. (2011) Generation and evaluation of A2-expressing Lactococcus lactis live vaccines against Leishmania donovani in BALB/c mice. J Med Microbiol.
    • (2011) J Med Microbiol
    • Yam, K.K.1    Hugentobler, F.2    Pouliot, P.3    Stern, A.M.4    Lalande, J.D.5
  • 30
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri G, (2003) Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 3: 133-146.
    • (2003) Nat Rev Immunol , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 31
    • 27544451339 scopus 로고    scopus 로고
    • 10 years of the nisin-controlled gene expression system (NICE) in Lactococcus lactis
    • Mierau I, Kleerebezem M, (2005) 10 years of the nisin-controlled gene expression system (NICE) in Lactococcus lactis. Appl Microbiol Biotechnol 68: 705-717.
    • (2005) Appl Microbiol Biotechnol , vol.68 , pp. 705-717
    • Mierau, I.1    Kleerebezem, M.2
  • 32
    • 0034911854 scopus 로고    scopus 로고
    • Leishmania donovani p36(LACK) DNA vaccine is highly immunogenic but not protective against experimental visceral leishmaniasis
    • Melby PC, Yang J, Zhao W, Perez LE, Cheng J, (2001) Leishmania donovani p36(LACK) DNA vaccine is highly immunogenic but not protective against experimental visceral leishmaniasis. Infect Immun 69: 4719-4725.
    • (2001) Infect Immun , vol.69 , pp. 4719-4725
    • Melby, P.C.1    Yang, J.2    Zhao, W.3    Perez, L.E.4    Cheng, J.5
  • 33
    • 0031944982 scopus 로고    scopus 로고
    • A nine-residue synthetic propeptide enhances secretion efficiency of heterologous proteins in Lactococcus lactis
    • Le Loir Y, Gruss A, Ehrlich SD, Langella P, (1998) A nine-residue synthetic propeptide enhances secretion efficiency of heterologous proteins in Lactococcus lactis. J Bacteriol 180: 1895-1903.
    • (1998) J Bacteriol , vol.180 , pp. 1895-1903
    • Le Loir, Y.1    Gruss, A.2    Ehrlich, S.D.3    Langella, P.4
  • 34
    • 0036151762 scopus 로고    scopus 로고
    • Production and targeting of the Brucella abortus antigen L7/L12 in Lactococcus lactis: a first step towards food-grade live vaccines against brucellosis
    • Ribeiro LA, Azevedo V, Le Loir Y, Oliveira SC, Dieye Y, et al. (2002) Production and targeting of the Brucella abortus antigen L7/L12 in Lactococcus lactis: a first step towards food-grade live vaccines against brucellosis. Appl Environ Microbiol 68: 910-916.
    • (2002) Appl Environ Microbiol , vol.68 , pp. 910-916
    • Ribeiro, L.A.1    Azevedo, V.2    Le Loir, Y.3    Oliveira, S.C.4    Dieye, Y.5
  • 35
    • 3042659382 scopus 로고    scopus 로고
    • Intranasal immunization with recombinant Lactococcus lactis secreting murine interleukin-12 enhances antigen-specific Th1 cytokine production
    • Bermudez-Humaran LG, Langella P, Cortes-Perez NG, Gruss A, Tamez-Guerra RS, et al. (2003) Intranasal immunization with recombinant Lactococcus lactis secreting murine interleukin-12 enhances antigen-specific Th1 cytokine production. Infection & Immunity 71: 1887-1896.
    • (2003) Infection & Immunity , vol.71 , pp. 1887-1896
    • Bermudez-Humaran, L.G.1    Langella, P.2    Cortes-Perez, N.G.3    Gruss, A.4    Tamez-Guerra, R.S.5
  • 36
    • 0028035351 scopus 로고
    • Genetic analysis of regions of the Lactococcus lactis subsp. lactis plasmid pRS01 involved in conjugative transfer
    • Mills DA, Choi CK, Dunny GM, McKay LL, (1994) Genetic analysis of regions of the Lactococcus lactis subsp. lactis plasmid pRS01 involved in conjugative transfer. Appl Environ Microbiol 60: 4413-4420.
    • (1994) Appl Environ Microbiol , vol.60 , pp. 4413-4420
    • Mills, D.A.1    Choi, C.K.2    Dunny, G.M.3    McKay, L.L.4
  • 37
    • 0030004213 scopus 로고    scopus 로고
    • Presentation of the protective parasite antigen LACK by Leishmania-infected macrophages
    • Prina E, Lang T, Glaichenhaus N, Antoine JC, (1996) Presentation of the protective parasite antigen LACK by Leishmania-infected macrophages. J Immunol 156: 4318-4327.
    • (1996) J Immunol , vol.156 , pp. 4318-4327
    • Prina, E.1    Lang, T.2    Glaichenhaus, N.3    Antoine, J.C.4
  • 38
    • 65549154373 scopus 로고    scopus 로고
    • Leishmania-induced IRAK-1 inactivation is mediated by SHP-1 interacting with an evolutionarily conserved KTIM motif
    • Abu-Dayyeh I, Shio MT, Sato S, Akira S, Cousineau B, et al. (2008) Leishmania-induced IRAK-1 inactivation is mediated by SHP-1 interacting with an evolutionarily conserved KTIM motif. PLoS Negl Trop Dis 2: e305.
    • (2008) PLoS Negl Trop Dis , vol.2
    • Abu-Dayyeh, I.1    Shio, M.T.2    Sato, S.3    Akira, S.4    Cousineau, B.5
  • 39
    • 77956697927 scopus 로고    scopus 로고
    • Leishmania parasite detection and quantification using PCR-ELISA
    • Kobets T, Badalova J, Grekov I, Havelkova H, Svobodova M, et al. (2010) Leishmania parasite detection and quantification using PCR-ELISA. Nat Protoc 5: 1074-1080.
    • (2010) Nat Protoc , vol.5 , pp. 1074-1080
    • Kobets, T.1    Badalova, J.2    Grekov, I.3    Havelkova, H.4    Svobodova, M.5
  • 40
    • 57149092803 scopus 로고    scopus 로고
    • HtrA is essential for efficient secretion of recombinant proteins by Lactococcus lactis
    • Sriraman K, Jayaraman G, (2008) HtrA is essential for efficient secretion of recombinant proteins by Lactococcus lactis. Appl Environ Microbiol 74: 7442-7446.
    • (2008) Appl Environ Microbiol , vol.74 , pp. 7442-7446
    • Sriraman, K.1    Jayaraman, G.2
  • 41
    • 34250303350 scopus 로고    scopus 로고
    • Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
    • Darrah PA, Patel DT, De Luca PM, Lindsay RW, Davey DF, et al. (2007) Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major. Nat Med 13: 843-850.
    • (2007) Nat Med , vol.13 , pp. 843-850
    • Darrah, P.A.1    Patel, D.T.2    De Luca, P.M.3    Lindsay, R.W.4    Davey, D.F.5
  • 42
    • 23444440849 scopus 로고    scopus 로고
    • IL-10 from regulatory T cells determines vaccine efficacy in murine Leishmania major infection
    • Stober CB, Lange UG, Roberts MT, Alcami A, Blackwell JM, (2005) IL-10 from regulatory T cells determines vaccine efficacy in murine Leishmania major infection. J Immunol 175: 2517-2524.
    • (2005) J Immunol , vol.175 , pp. 2517-2524
    • Stober, C.B.1    Lange, U.G.2    Roberts, M.T.3    Alcami, A.4    Blackwell, J.M.5
  • 43
  • 44
    • 0035863867 scopus 로고    scopus 로고
    • The role of IL-10 in promoting disease progression in leishmaniasis
    • Kane MM, Mosser DM, (2001) The role of IL-10 in promoting disease progression in leishmaniasis. J Immunol 166: 1141-1147.
    • (2001) J Immunol , vol.166 , pp. 1141-1147
    • Kane, M.M.1    Mosser, D.M.2
  • 45
    • 15444364277 scopus 로고    scopus 로고
    • A role for IgG immune complexes during infection with the intracellular pathogen Leishmania
    • Miles SA, Conrad SM, Alves RG, Jeronimo SM, Mosser DM, (2005) A role for IgG immune complexes during infection with the intracellular pathogen Leishmania. J Exp Med 201: 747-754.
    • (2005) J Exp Med , vol.201 , pp. 747-754
    • Miles, S.A.1    Conrad, S.M.2    Alves, R.G.3    Jeronimo, S.M.4    Mosser, D.M.5
  • 46
    • 0038560975 scopus 로고    scopus 로고
    • The relative contribution of IL-4 receptor signaling and IL-10 to susceptibility to Leishmania major
    • Noben-Trauth N, Lira R, Nagase H, Paul WE, Sacks DL, (2003) The relative contribution of IL-4 receptor signaling and IL-10 to susceptibility to Leishmania major. J Immunol 170: 5152-5158.
    • (2003) J Immunol , vol.170 , pp. 5152-5158
    • Noben-Trauth, N.1    Lira, R.2    Nagase, H.3    Paul, W.E.4    Sacks, D.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.