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Volumn 4, Issue 1, 2010, Pages 32-39

Non-alcoholic Fatty Liver Disease and Cardiovascular Disease Risk

Author keywords

Cardiovascular disease; Metabolic syndrome; Non alcoholic fatty liver disease; Risk factors

Indexed keywords


EID: 84856744556     PISSN: 19329520     EISSN: 19329563     Source Type: Journal    
DOI: 10.1007/s12170-009-0070-3     Document Type: Article
Times cited : (4)

References (50)
  • 1
    • 35348900749 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Adams LA, Lindor KD: Nonalcoholic fatty liver disease. Ann Epidemiol 2007, 17: 863-869.
    • (2007) Ann Epidemiol , vol.17 , pp. 863-869
    • Adams, L.A.1    Lindor, K.D.2
  • 2
    • 40849083460 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: the mist gradually clears
    • This is a comprehensive review on epidemiology, diagnosis, pathophysiology, clinical complications, and treatment of NAFLD
    • • de Alwis NMW, Day CP: Nonalcoholic fatty liver disease: the mist gradually clears. J Hepatol 2008, 48(Suppl 1): S104-S112. This is a comprehensive review on epidemiology, diagnosis, pathophysiology, clinical complications, and treatment of NAFLD.
    • (2008) J Hepatol , vol.48 , Issue.SUPPL. 1
    • de Alwis, N.M.W.1    Day, C.P.2
  • 3
    • 37549047145 scopus 로고    scopus 로고
    • Fatty liver: a novel component of the metabolic syndrome
    • This elegant review summarizes the clinical and epidemiologic evidence for a strong association between NAFLD and the metabolic syndrome
    • • Kotronen A, Yki-Järvinen H: Fatty liver: a novel component of the metabolic syndrome. Arterioscler Thromb Vasc Biol 2008, 28: 27-38. This elegant review summarizes the clinical and epidemiologic evidence for a strong association between NAFLD and the metabolic syndrome.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 27-38
    • Kotronen, A.1    Yki-Järvinen, H.2
  • 4
    • 34247605492 scopus 로고    scopus 로고
    • Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients
    • This is the largest cross-sectional study assessing the prevalence rates of coronary, cerebrovascular, and peripheral vascular disease in 2839 unselected type 2 diabetic outpatients with and without NAFLD as diagnosed by liver ultrasound
    • • Targher G, Bertolini L, Padovani R, et al.: Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients. Diabetes Care 2007, 30: 1212-1218. This is the largest cross-sectional study assessing the prevalence rates of coronary, cerebrovascular, and peripheral vascular disease in 2839 unselected type 2 diabetic outpatients with and without NAFLD as diagnosed by liver ultrasound.
    • (2007) Diabetes Care , vol.30 , pp. 1212-1218
    • Targher, G.1    Bertolini, L.2    Padovani, R.3
  • 5
    • 0037382786 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome
    • Marchesini G, Bugianesi E, Forlani G, et al.: Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology 2003, 37: 917-923.
    • (2003) Hepatology , vol.37 , pp. 917-923
    • Marchesini, G.1    Bugianesi, E.2    Forlani, G.3
  • 6
    • 42949154244 scopus 로고    scopus 로고
    • Diagnosis and therapy of nonalcoholic steatohepatitis
    • Torres DM, Harrison SA: Diagnosis and therapy of nonalcoholic steatohepatitis. Gastroenterology 2008, 134: 1682-1698.
    • (2008) Gastroenterology , vol.134 , pp. 1682-1698
    • Torres, D.M.1    Harrison, S.A.2
  • 7
    • 23044512117 scopus 로고    scopus 로고
    • Endothelial dysfunction and cardiovascular risk profile in nonalcoholic fatty liver disease
    • Villanova N, Moscatiello S, Ramilli S, et al.: Endothelial dysfunction and cardiovascular risk profile in nonalcoholic fatty liver disease. Hepatology 2005, 42: 473-480.
    • (2005) Hepatology , vol.42 , pp. 473-480
    • Villanova, N.1    Moscatiello, S.2    Ramilli, S.3
  • 8
    • 20444455921 scopus 로고    scopus 로고
    • Liver alanine aminotransferase, insulin resistance and endothelial dysfunction in normotriglyceridaemic subjects with type 2 diabetes mellitus
    • Schindhelm RK, Diamant M, Bakker SJ, et al.: Liver alanine aminotransferase, insulin resistance and endothelial dysfunction in normotriglyceridaemic subjects with type 2 diabetes mellitus. Eur J Clin Invest 2005, 35: 369-374.
    • (2005) Eur J Clin Invest , vol.35 , pp. 369-374
    • Schindhelm, R.K.1    Diamant, M.2    Bakker, S.J.3
  • 9
    • 4644305245 scopus 로고    scopus 로고
    • Relation of nonalcoholic hepatic steatosis to early carotid atherosclerosis in healthy men: role of visceral fat accumulation
    • Targher G, Bertolini L, Padovani R, et al.: Relation of nonalcoholic hepatic steatosis to early carotid atherosclerosis in healthy men: role of visceral fat accumulation. Diabetes Care 2004, 27: 2498-2500.
    • (2004) Diabetes Care , vol.27 , pp. 2498-2500
    • Targher, G.1    Bertolini, L.2    Padovani, R.3
  • 11
    • 17144387889 scopus 로고    scopus 로고
    • Hepatic steatosis is associated with an increased risk of carotid atherosclerosis
    • Volzke H, Robinson DM, Kleine V, et al.: Hepatic steatosis is associated with an increased risk of carotid atherosclerosis. World J Gastroenterol 2005, 11: 1848-1853.
    • (2005) World J Gastroenterol , vol.11 , pp. 1848-1853
    • Volzke, H.1    Robinson, D.M.2    Kleine, V.3
  • 12
    • 37649012018 scopus 로고    scopus 로고
    • Carotid artery intima-media thickness in nonalcoholic fatty liver disease
    • Fracanzani AL, Burdick L, Raselli S, et al.: Carotid artery intima-media thickness in nonalcoholic fatty liver disease. Am J Med 2008, 121: 72-78.
    • (2008) Am J Med , vol.121 , pp. 72-78
    • Fracanzani, A.L.1    Burdick, L.2    Raselli, S.3
  • 13
    • 33746421488 scopus 로고    scopus 로고
    • Relations between carotid artery wall thickness and liver histology in subjects with nonalcoholic fatty liver disease
    • Targher G, Bertolini L, Padovani R, et al.: Relations between carotid artery wall thickness and liver histology in subjects with nonalcoholic fatty liver disease. Diabetes Care 2006, 29: 1325-1330.
    • (2006) Diabetes Care , vol.29 , pp. 1325-1330
    • Targher, G.1    Bertolini, L.2    Padovani, R.3
  • 14
    • 58149378362 scopus 로고    scopus 로고
    • Hepatic steatosis and subclinical cardiovascular disease in a cohort enriched for type 2 diabetes: the Diabetes Heart Study
    • McKimmie RL, Daniel KR, Carr JJ, et al.: Hepatic steatosis and subclinical cardiovascular disease in a cohort enriched for type 2 diabetes: the Diabetes Heart Study. Am J Gastroenterol 2008, 103: 3029-3035.
    • (2008) Am J Gastroenterol , vol.103 , pp. 3029-3035
    • McKimmie, R.L.1    Daniel, K.R.2    Carr, J.J.3
  • 15
    • 50849096389 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease is strongly associated with carotid atherosclerosis: a systematic review
    • Sookoian S, Pirola CJ: Non-alcoholic fatty liver disease is strongly associated with carotid atherosclerosis: a systematic review. J Hepatol 2008, 49: 600-607.
    • (2008) J Hepatol , vol.49 , pp. 600-607
    • Sookoian, S.1    Pirola, C.J.2
  • 16
    • 33750630075 scopus 로고    scopus 로고
    • Cardiac abnormalities as a new manifestation of nonalcoholic fatty liver disease: echocardiographic and tissue Doppler imaging assessment
    • Goland S, Shimoni S, Zornitzki T, et al.: Cardiac abnormalities as a new manifestation of nonalcoholic fatty liver disease: echocardiographic and tissue Doppler imaging assessment. J Clin Gastroenterol 2006, 40: 949-955.
    • (2006) J Clin Gastroenterol , vol.40 , pp. 949-955
    • Goland, S.1    Shimoni, S.2    Zornitzki, T.3
  • 17
    • 38649091680 scopus 로고    scopus 로고
    • Increased mediastinal fat and impaired left ventricular energy metabolism in young men with newly found fatty liver
    • Perseghin G, Lattuada G, De Cobelli F, et al.: Increased mediastinal fat and impaired left ventricular energy metabolism in young men with newly found fatty liver. Hepatology 2008, 47: 51-58.
    • (2008) Hepatology , vol.47 , pp. 51-58
    • Perseghin, G.1    Lattuada, G.2    de Cobelli, F.3
  • 18
    • 24044476188 scopus 로고    scopus 로고
    • Sonographic fatty liver, overweight and ischemic heart disease
    • Lin YC, Lo HM, Chen JD: Sonographic fatty liver, overweight and ischemic heart disease. World J Gastroenterol 2005, 11: 4838-4842.
    • (2005) World J Gastroenterol , vol.11 , pp. 4838-4842
    • Lin, Y.C.1    Lo, H.M.2    Chen, J.D.3
  • 19
    • 39049102073 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and proliferative/laser-treated retinopathy in type 2 diabetic patients
    • Targher G, Bertolini L, Rodella S, et al.: Non-alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and proliferative/laser-treated retinopathy in type 2 diabetic patients. Diabetologia 2008, 51: 444-450.
    • (2008) Diabetologia , vol.51 , pp. 444-450
    • Targher, G.1    Bertolini, L.2    Rodella, S.3
  • 20
  • 21
    • 33745856570 scopus 로고    scopus 로고
    • Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in patients with type 2 diabetes
    • Lautamäki R, Borra R, Iozzo P, et al.: Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in patients with type 2 diabetes. Am J Physiol Endocrinol Metab 2006, 291: E282-E290.
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Lautamäki, R.1    Borra, R.2    Iozzo, P.3
  • 23
    • 53549112749 scopus 로고    scopus 로고
    • Increased risk of cardiovascular disease in non-alcoholic fatty liver disease: causal effect or epiphenomenon?
    • This is a comprehensive review on the relationship between NAFLD and CVD risk
    • •• Targher G, Marra F, Marchesini G: Increased risk of cardiovascular disease in non-alcoholic fatty liver disease: causal effect or epiphenomenon? Diabetologia 2008, 51: 1947-1953. This is a comprehensive review on the relationship between NAFLD and CVD risk.
    • (2008) Diabetologia , vol.51 , pp. 1947-1953
    • Targher, G.1    Marra, F.2    Marchesini, G.3
  • 24
    • 22344452893 scopus 로고    scopus 로고
    • The natural history of nonalcoholic fatty liver disease: a population-based cohort study
    • Adams LA, Lymp JF, St Sauver J, et al.: The natural history of nonalcoholic fatty liver disease: a population-based cohort study. Gastroenterology 2005, 129: 113-121.
    • (2005) Gastroenterology , vol.129 , pp. 113-121
    • Adams, L.A.1    Lymp, J.F.2    St Sauver, J.3
  • 25
    • 0033038672 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity
    • Matteoni CA, Younossi ZM, Gramlich T, et al.: Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999, 116: 1413-1419.
    • (1999) Gastroenterology , vol.116 , pp. 1413-1419
    • Matteoni, C.A.1    Younossi, Z.M.2    Gramlich, T.3
  • 26
    • 33750606061 scopus 로고    scopus 로고
    • Long-term follow-up of patients with NAFLD and elevated liver enzymes
    • Ekstedt M, Franzen LE, Mathiesen UL, et al.: Long-term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology 2006, 44: 865-873.
    • (2006) Hepatology , vol.44 , pp. 865-873
    • Ekstedt, M.1    Franzen, L.E.2    Mathiesen, U.L.3
  • 27
    • 84873525435 scopus 로고    scopus 로고
    • Decreased survival of subjects with elevated liver function tests during a 28-year follow-up
    • In press
    • Soderberg C, Stäl P, Askling J, et al.: Decreased survival of subjects with elevated liver function tests during a 28-year follow-up. Hepatology 2009, In press.
    • (2009) Hepatology
    • Soderberg, C.1    Stäl, P.2    Askling, J.3
  • 28
    • 26944453966 scopus 로고    scopus 로고
    • Gamma-glutamyltransferase as a risk factor for cardiovascular disease mortality: an epidemiological investigation in a cohort of 163, 944 Austrian adults
    • Ruttmann E, Brant LJ, Concin H, et al.: Gamma-glutamyltransferase as a risk factor for cardiovascular disease mortality: an epidemiological investigation in a cohort of 163, 944 Austrian adults. Circulation 2005, 112: 2130-2137.
    • (2005) Circulation , vol.112 , pp. 2130-2137
    • Ruttmann, E.1    Brant, L.J.2    Concin, H.3
  • 29
    • 33847619687 scopus 로고    scopus 로고
    • Gamma-glutamyltransferase and metabolic syndrome, cardiovascular disease, and mortality risk: the Framingham Heart Study
    • Lee DS, Evans JC, Robins SJ, et al.: Gamma-glutamyltransferase and metabolic syndrome, cardiovascular disease, and mortality risk: the Framingham Heart Study. Arterioscler Thromb Vasc Biol 2007, 27: 127-133.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 127-133
    • Lee, D.S.1    Evans, J.C.2    Robins, S.J.3
  • 30
    • 50649094716 scopus 로고    scopus 로고
    • Suspected nonalcoholic fatty liver disease and mortality risk in a population-based cohort study
    • Dunn W, Xu R, Wingard DL, et al.: Suspected nonalcoholic fatty liver disease and mortality risk in a population-based cohort study. Am J Gastroenterol 2008, 103: 2263-2271.
    • (2008) Am J Gastroenterol , vol.103 , pp. 2263-2271
    • Dunn, W.1    Xu, R.2    Wingard, D.L.3
  • 31
    • 33947169979 scopus 로고    scopus 로고
    • Alanine aminotransferase predicts coronary heart disease events: a 10-year follow-up of the Hoorn Study
    • Schindhelm RK, Dekker JM, Nijpels G, et al.: Alanine aminotransferase predicts coronary heart disease events: a 10-year follow-up of the Hoorn Study. Atherosclerosis 2007, 191: 391-396.
    • (2007) Atherosclerosis , vol.191 , pp. 391-396
    • Schindhelm, R.K.1    Dekker, J.M.2    Nijpels, G.3
  • 32
    • 72949097025 scopus 로고    scopus 로고
    • Ultrasonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl-transpeptidase levels
    • In a population-based cohort of 4160 German individuals followed up for a median period of 7.3 years, it was shown that ultrasound-diagnosed NAFLD predicts all-cause and CVD mortality in men independently of cardiometabolic risk factors. These authors also have shown that in case of increased serum GGT levels, liver ultrasound should be performed not only for the diagnosis of NAFLD, but also for further CVD risk stratification
    • •• Haring R, Wallaschofski H, Nauck M, et al.: Ultrasonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl-transpeptidase levels. Hepatology 2009, 50: 1403-1411. In a population-based cohort of 4160 German individuals followed up for a median period of 7. 3 years, it was shown that ultrasound-diagnosed NAFLD predicts all-cause and CVD mortality in men independently of cardiometabolic risk factors. These authors also have shown that in case of increased serum GGT levels, liver ultrasound should be performed not only for the diagnosis of NAFLD, but also for further CVD risk stratification.
    • (2009) Hepatology , vol.50 , pp. 1403-1411
    • Haring, R.1    Wallaschofski, H.2    Nauck, M.3
  • 33
    • 36349033483 scopus 로고    scopus 로고
    • Gamma-glutamyltransferase is associated with incident vascular events independently of alcohol intake: analysis of the British Women's Heart and Health Study and Meta-Analysis
    • Fraser A, Harris R, Sattar N, et al.: Gamma-glutamyltransferase is associated with incident vascular events independently of alcohol intake: analysis of the British Women's Heart and Health Study and Meta-Analysis. Arterioscler Thromb Vasc Biol 2007, 27: 2729-2735.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2729-2735
    • Fraser, A.1    Harris, R.2    Sattar, N.3
  • 34
    • 33644700376 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and risk of future cardiovascular events among type 2 diabetic patients
    • Targher G, Bertolini L, Poli F, et al.: Nonalcoholic fatty liver disease and risk of future cardiovascular events among type 2 diabetic patients. Diabetes 2005, 54: 3541-3546.
    • (2005) Diabetes , vol.54 , pp. 3541-3546
    • Targher, G.1    Bertolini, L.2    Poli, F.3
  • 35
    • 34547673500 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is independently associated with an increased incidence of cardiovascular events in type 2 diabetic patients
    • In an outpatient cohort of 2103 type 2 diabetic individuals followed for 6.5 years, it was shown that ultrasound-diagnosed NAFLD predicts fatal and nonfatal CVD events independently of traditional risk factors, diabetes duration, glycemic control, current use of medications, and metabolic syndrome components
    • •• Targher G, Bertolini L, Rodella S, et al.: Nonalcoholic fatty liver disease is independently associated with an increased incidence of cardiovascular events in type 2 diabetic patients. Diabetes Care 2007, 30: 2119-2121. In an outpatient cohort of 2103 type 2 diabetic individuals followed for 6. 5 years, it was shown that ultrasound-diagnosed NAFLD predicts fatal and nonfatal CVD events independently of traditional risk factors, diabetes duration, glycemic control, current use of medications, and metabolic syndrome components.
    • (2007) Diabetes Care , vol.30 , pp. 2119-2121
    • Targher, G.1    Bertolini, L.2    Rodella, S.3
  • 36
    • 49649090452 scopus 로고    scopus 로고
    • Increased risk of CKD among type 2 diabetics with nonalcoholic fatty liver disease
    • Targher G, Chonchol M, Bertolini L, et al.: Increased risk of CKD among type 2 diabetics with nonalcoholic fatty liver disease. J Am Soc Nephrol 2008, 19: 1564-1570.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1564-1570
    • Targher, G.1    Chonchol, M.2    Bertolini, L.3
  • 37
    • 34247647418 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is a novel predictor of cardiovascular disease
    • In a community-based cohort of 1637 nondiabetic Japanese individuals followed for a mean period of 5 years, it was shown that ultrasound-diagnosed NAFLD predicts incident CVD events in both men and women independently of classical risk factors and metabolic syndrome components
    • •• Hamaguchi M, Kojima T, Takeda N, et al.: Nonalcoholic fatty liver disease is a novel predictor of cardiovascular disease. World J Gastroenterol 2007, 13: 1579-1584. In a community-based cohort of 1, 637 nondiabetic Japanese individuals followed for a mean period of 5 years, it was shown that ultrasound-diagnosed NAFLD predicts incident CVD events in both men and women independently of classical risk factors and metabolic syndrome components.
    • (2007) World J Gastroenterol , vol.13 , pp. 1579-1584
    • Hamaguchi, M.1    Kojima, T.2    Takeda, N.3
  • 38
    • 33845914986 scopus 로고    scopus 로고
    • Mechanisms linking obesity with cardiovascular disease
    • van Gaal LF, Mertens IL, De Block CE: Mechanisms linking obesity with cardiovascular disease. Nature 2006, 444: 875-880.
    • (2006) Nature , vol.444 , pp. 875-880
    • van Gaal, L.F.1    Mertens, I.L.2    de Block, C.E.3
  • 39
    • 57349116780 scopus 로고    scopus 로고
    • Causes and metabolic consequences of fatty liver
    • This review focuses on the mechanisms involved in the pathogenesis of hepatic fat accumulation, particularly the roles of body fat distribution, nutrition, exercise, genetics, and gene-environment interaction. Furthermore, the effects of fatty liver on glucose and lipid metabolism, specifically via induction of subclinical inflammation and secretion of humoral factors, are highlighted
    • • Stefan N, Kantartzis K, Häring HU: Causes and metabolic consequences of fatty liver. Endocr Rev 2008, 29: 939-960. This review focuses on the mechanisms involved in the pathogenesis of hepatic fat accumulation, particularly the roles of body fat distribution, nutrition, exercise, genetics, and gene-environment interaction. Furthermore, the effects of fatty liver on glucose and lipid metabolism, specifically via induction of subclinical inflammation and secretion of humoral factors, are highlighted.
    • (2008) Endocr Rev , vol.29 , pp. 939-960
    • Stefan, N.1    Kantartzis, K.2    Häring, H.U.3
  • 40
    • 42949178538 scopus 로고    scopus 로고
    • Liver, muscle, and adipose tissue insulin action is directly related to intra-hepatic triglyceride content in obese subjects
    • Korenblat KM, Fabbrini E, Mohammed BS, Klein S: Liver, muscle, and adipose tissue insulin action is directly related to intra-hepatic triglyceride content in obese subjects. Gastroenterology 2008, 134: 1369-1375.
    • (2008) Gastroenterology , vol.134 , pp. 1369-1375
    • Korenblat, K.M.1    Fabbrini, E.2    Mohammed, B.S.3    Klein, S.4
  • 41
    • 33746597352 scopus 로고    scopus 로고
    • Influence of hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in type 2 diabetes
    • Toledo FG, Sniderman AD, Kelley DE: Influence of hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in type 2 diabetes. Diabetes Care 2006, 29: 1845-1850.
    • (2006) Diabetes Care , vol.29 , pp. 1845-1850
    • Toledo, F.G.1    Sniderman, A.D.2    Kelley, D.E.3
  • 42
    • 0034676629 scopus 로고    scopus 로고
    • Cytokines in alcoholic and nonalcoholic steatohepatitis
    • Tilg H, Diehl AM: Cytokines in alcoholic and nonalcoholic steatohepatitis. N Engl J Med 2000, 343: 1467-1476.
    • (2000) N Engl J Med , vol.343 , pp. 1467-1476
    • Tilg, H.1    Diehl, A.M.2
  • 43
    • 67649170396 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease as a contributor to hypercoagulation and thrombophilia in the metabolic syndrome
    • This is a comprehensive review on the relationships of NAFLD with plasma inflammatory and hemostatic biomarkers
    • • Targher G, Chonchol M, Miele L, et al.: Nonalcoholic fatty liver disease as a contributor to hypercoagulation and thrombophilia in the metabolic syndrome. Semin Thromb Hemost 2009, 35: 277-287. This is a comprehensive review on the relationships of NAFLD with plasma inflammatory and hemostatic biomarkers.
    • (2009) Semin Thromb Hemost , vol.35 , pp. 277-287
    • Targher, G.1    Chonchol, M.2    Miele, L.3
  • 44
    • 44449109670 scopus 로고    scopus 로고
    • NASH predicts plasma inflammatory biomarkers independently of visceral fat in men
    • Targher G, Bertolini L, Rodella S, et al.: NASH predicts plasma inflammatory biomarkers independently of visceral fat in men. Obesity (Silver Spring) 2008, 16: 1394-1399.
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 1394-1399
    • Targher, G.1    Bertolini, L.2    Rodella, S.3
  • 46
    • 3042744737 scopus 로고    scopus 로고
    • Beyond insulin resistance in NASH: TNF-alpha or adiponectin?
    • Hui JM, Hodge A, Farrell GC, et al.: Beyond insulin resistance in NASH: TNF-alpha or adiponectin? Hepatology 2004, 40: 46-54.
    • (2004) Hepatology , vol.40 , pp. 46-54
    • Hui, J.M.1    Hodge, A.2    Farrell, G.C.3
  • 47
    • 33646853899 scopus 로고    scopus 로고
    • Associations between plasma adiponectin concentrations and liver histology in patients with nonalcoholic fatty liver disease
    • Targher G, Bertolini L, Rodella S, et al.: Associations between plasma adiponectin concentrations and liver histology in patients with nonalcoholic fatty liver disease. Clin Endocrinol 2006, 64: 679-683.
    • (2006) Clin Endocrinol , vol.64 , pp. 679-683
    • Targher, G.1    Bertolini, L.2    Rodella, S.3
  • 48
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu A, Wang Y, Keshaw H, et al.: The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003, 112: 91-100.
    • (2003) J Clin Invest , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3
  • 49
    • 0037382071 scopus 로고    scopus 로고
    • Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis
    • Musso G, Gambino R, De Michieli F, et al.: Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis. Hepatology 2003, 37: 909-916.
    • (2003) Hepatology , vol.37 , pp. 909-916
    • Musso, G.1    Gambino, R.2    de Michieli, F.3


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