Postprandial lipemia associates with liver fat content

Journal of Clinical Endocrinology and Metabolism

Volumn 92, Issue 8, 2007, Pages 3052-3059

  Matikainen, Niina ^a   Mänttäri, Sakari ^a   Westerbacka, Jukka ^a   Vehkavaara, Satu ^a   Lundbom, Nina ^a   Yki Järvinen, Hannele ^a   Taskinen, Marja Riitta ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; APOLIPOPROTEIN B100; APOLIPOPROTEIN B48; CHOLESTEROL; CHYLOMICRON; LIPOPROTEIN; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ABDOMINAL FAT; ADULT; AREA UNDER THE CURVE; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; FAT CONTENT; GLUCOSE METABOLISM; HUMAN; HYPERLIPIDEMIA; LIPID BLOOD LEVEL; LIVER; MALE; MULTIPLE LINEAR REGRESSION ANALYSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OBESITY; PRIORITY JOURNAL; RISK FACTOR;

EID: 34547750961     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2007-0187     Document Type: Article

References (45)

1. Taskinen MR 2003 Diabetic dyslipidaemia: from basic research to clinical practice. Diabetologia 46:733-749
2. Boden G, Laakso M 2004 Lipids and glucose in type 2 diabetes: what is the cause and effect? Diabetes Care 27:2253-2259
3. Karpe F, Steiner G, Uffelman K, Olivecrona T, Hamsten A 1994 Postprandial lipoproteins and progression of coronary atherosclerosis. Atherosclerosis 106:83-97
4. Kugiyama K, Doi H, Motoyama T, Soejima H, Misumi K, Kawano H, Nakagawa O, Yoshimura M, Ogawa H, Matsumura T, Sugiyama S, Nakano T, Nakajima K, Yasue H 1998 Association of remnant lipoprotein levels with impairment of endothelium-dependent vasomotor function in human coronary arteries. Circulation 97:2519-2526
5. Mero N, Malmström R, Steiner G, Taskinen MR, Syvänne M 2000 Postprandial metabolism of apolipoprotein B-48- and B-100-containing particles in type 2 diabetes mellitus: relations to angiographically verified severity of coronary artery disease. Atherosclerosis 150:167-177
6. Ginsberg HN, Illingworth DR 2001 Postprandial dyslipidemia: an atherogenic disorder common in patients with diabetes mellitus. Am J Cardiol 88:20
7. Twickler TB, Dallinga-Thie GM, Cohn JS, Chapman MJ 2004 Elevated remnant-like particle cholesterol concentration: a characteristic feature of the atherogenic lipoprotein phenotype. Circulation 109:1918-1925
8. Blackburn P, Cote M, Lamarche B, Couillard C, Pascot A, Tremblay A, Bergeron J, Lemieux I, Despres JP 2003 Impact of postprandial variation in triglyceridemia on low-density lipoprotein particle size. Metabolism 52:1379-1386
9. Zhao SP, Liu L, Gao M, Zhou QC, Li YL, Xia B 2001 Impairment of endothelial function after a high-fat meal in patients with coronary artery disease. Coron Artery Dis 12:561-565
10. Ceriello A, Taboga C, Tonutti L, Quagliaro L, Piconi L, Bais B, Da Ros R, Motz E 2002 Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: effects of short- and long-term simvastatin treatment. Circulation 106:1211-1218
11. Ceriello A, Assaloni R, Da Ros R, Maier A, Piconi L, Quagliaro L, Esposito K, Giugliano D 2005 Effect of atorvastatin and irbesartan, alone and in combination, on postprandial endothelial dysfunction, oxidative stress, and inflammation in type 2 diabetic patients. Circulation 111:2518-2524
12. Tolman KG, Fonseca V, Tan MH, Dalpiaz A 2004 Narrative review: hepatobiliary disease in type 2 diabetes mellitus. Ann Intern Med 141:946-956
13. Marchesini G, Brizi M, Morselli-Labate AM, Bianchi G, Bugianesi E, McCullough AJ, Forlani G, Melchionda N 1999 Association of nonalcoholic fatty liver disease with insulin resistance. Am J Med 107:450-455
14. Marchesini G, Marzocchi R, Agostini F, Bugianesi E 2005 Nonalcoholic fatty liver disease and the metabolic syndrome. Curr Opin Lipidol 16:421-427
15. Yki-Järvinen H, Westerbacka J 2005 The fatty liver and insulin resistance. Curr Molec Med 5:287-295
16. Kelley DE, McKolanis TM, Hegazi RA, Kuller LH, Kalhan SC 2003 Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance. Am J Physiol 285:E906-E916
17. Toledo FG, Sniderman AD, Kelley DE 2006 Influence of hepatic steatosis (fatty liver) on severity and composition of dyslipidemia in type 2 diabetes. Diabetes Care 29:1845-1850
18. Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ 2005 Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 115:1343-1351
19. Westerbacka J, Corner A, Tiikkainen M, Tamminen M, Vehkavaara S, Häkkinen AM, Fredriksson J, Yki-Järvinen H 2004 Women and men have similar amounts of liver and intra-abdominal fat, despite more subcutaneous fat in women: implications for sex differences in markers of cardiovascular risk. Diabetologia 47:1360-1369
20. Adiels M, Olofsson SO, Taskinen MR, Boren J 2006 Diabetic dyslipidaemia. Curr Opin Lipidol 17:238-246
21. Adiels M, Taskinen MR, Packard C, Caslake MJ, Soro-Paavonen A, Westerbacka J, Vehkavaara S, Häkkinen A, Olofsson SO, Yki-Järvinen H, Boren J 2006 Overproduction of large VLDL particles is driven by increased liver fat content in man. Diabetologia 49:755-765
22. Szczepaniak LS, Nurenberg P, Leonard D, Browning JD, Reingold JS, Grundy S, Hobbs HH, Dobbins RL 2005 Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population. Am J Physiol 288:E462-E468
23. Longo R, Pollesello P, Ricci C, Masutti F, Kvam BJ, Bercich L, Croce LS, Grigolato P, Paoletti S, de Bernard B, Tiribelli C, Palma LD 1995 Proton MR spectroscopy in quantitative in vivo determination of fat content in human liver steatosis. Magn Res Imag 5:281-285
24. Thomsen C, Becker U, Winkler K, Christoffersen P, Jensen M, Henriksen O 1994 Quantification of liver fat using magnetic resonance spectroscopy. Magn Res Imag 12:487-495
25. DeFronzo RA, Tobin JD, Andres R 1979 Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237:E214-E223
26. Mero N, Syvänne M, Eliasson B, Smith U, Taskinen M-R 1997 Postprandial elevation of apoB-48-containing triglyceride-rich particles and retinyl esters in normolipemic men who smoke. Arterioscler Thromb Vasc Biol 17:2096-2102
27. Karpe F, Hamsten A 1994 Determination of apolipoproteins B-48 and B-100 in triglyceride-rich lipoproteins by analytical SDS-PAGE. J Lipid Res 35:1311-1317
28. Matthews J, Altman D, Campbell M, Royston P 1990 Analysis of serial measurements in medical research. Br Med J 300:230-235
29. Ng TW, Watts GF, Farvid MS, Chan DC, Barrett PH 2005 Adipocytokines and VLDL metabolism: independent regulatory effects of adiponectin, insulin resistance, and fat compartments on VLDL apolipoprotein B-100 kinetics? Diabetes 54:795-802
30. Chan DC, Watts GF, Ng TW, Uchida Y, Sakai N, Yamashita S, Barrett PH 2005 Adiponectin and other adipocytokines as predictors of markers of triglyceride-rich lipoprotein metabolism. Clin Chem 51:578-585
31. Musso G, Gambino R, De Michieli F, Cassader M, Rizzetto M, Durazzo M, Faga E, Silli B, Pagano G 2003 Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis. Hepatology 37:909-916
32. Yki-Järvinen H 2005 Fat in the liver and insulin resistance. Ann Med 37:347-356
33. Adiels M, Boren J, Caslake MJ, Stewart P, Soro A, Westerbacka J, Wennberg B, Olofsson SO, Packard C, Taskinen MR 2005 Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia. Arterioscler Thromb Vasc Biol 25:1697-1703
34. Tiikkainen M, Tamminen M, Häkkinen AM, Bergholm R, Vehkavaara S, Halavaara J, Teramo K, Rissanen A, Yki-Järvinen H 2002 Liver-fat accumulation and insulin resistance in obese women with previous gestational diabetes. Obesity Res 10:859-867
35. Ryysy L, Häkkinen AM, Goto T, Vehkavaara S, Westerbacka J, Halavaara J, Yki-Järvinen H 2000 Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients. Diabetes 49:749-758
36. Seppälä-Lindroos A, Vehkavaara S, Häkkinen AM, Goto T, Westerbacka J, Sovijärvi A, Halavaara J, Yki-Järvinen H 2002 Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. J Clin Endocrinol Metab 87:3023-3028
37. Carey PE, Gerrard J, Cline GW, Man CD, English PT, Firbank MJ, Cobelli C, Taylor R 2005 Acute inhibition of lipolysis does not affect postprandial suppression of endogenous glucose production. Am J Physiol 289:E941-E947
38. Utzschneider KM, Kahn SE 2006 The role of insulin resistance in nonalcoholic fatty liver disease. J Clin Endocrinol Metab 91:4753-4761
39. Savage DB, Choi CS, Samuel VT, Liu ZX, Zhang D, Wang A, Zhang XM, Cline GW, Yu XX, Geisler JG, Bhanot S, Monia BP, Shulman GI 2006 Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2. J Clin Invest 116:817-824
40. Samuel VT, Liu ZX, Wang A, Beddow SA, Geisler JG, Kahn M, Zhang XM, Monia BP, Bhanot S, Shulman GI 2007 Inhibition of protein kinase Cε prevents hepatic insulin resistance in nonalcoholic fatty liver disease. J Clin Invest 117:739-745
41. Tiikkainen M, Bergholm R, Vehkavaara S, Rissanen A, Häkkinen AM, Tamminen M, Teramo K, Yki-Järvinen H 2003 Effects of identical weight loss on body composition and features of insulin resistance in obese women with high and low liver fat content. Diabetes 52:701-707
42. Blackburn P, Lamarche B, Couillard C, Pascot A, Tremblay A, Bergeron J, Lemieux I, Despres JP 2003 Contribution of visceral adiposity to the exaggerated postprandial lipemia of men with impaired glucose tolerance. Diabetes Care 26:3303-3309
43. Schneider JG, von Eynatten M, Schiekofer S, Nawroth PP, Dugi KA 2005 Low plasma adiponectin levels are associated with increased hepatic lipase activity in vivo. Diabetes Care 28:2181-2186
44. von Eynatten M, Schneider JG, Humpert PM, Rudofsky G, Schmidt N, Barosch P, Hamann A, Morcos M, Kreuzer J, Bierhaus A, Nawroth PP, Dugi KA 2004 Decreased plasma lipoprotein lipase in hypoadiponectinemia: an association independent of systemic inflammation and insulin resistance. Diabetes Care 27:2925-2929
45. Baratta R, Amato S, Degano C, Farina MG, Patane G, Vigneri R, Frittitta L 2004 Adiponectin relationship with lipid metabolism is independent of body fat mass: evidence from both cross-sectional and intervention studies. J Clin Endocrinol Metab 89:2665-2671