Suspected nonalcoholic fatty liver disease and mortality risk in a population-based cohort study

American Journal of Gastroenterology

Volumn 103, Issue 9, 2008, Pages 2263-2271

  Dunn, Winston ^a   Xu, Ronghui ^b   Wingard, Deborah L ^b   Rogers, Christopher ^c   Angulo, Paul ^d   Younossi, Zobair M ^e   Schwimmer, Jeffrey B ^f  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL CENTER FOR HEALTH STATISTICS   (United States)

^d MAYO CLINIC   (United States)

^e INOVA FAIRFAX HOSPITAL   (United States)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CARDIOVASCULAR RISK; CAUSE OF DEATH; CONTROLLED STUDY; FEMALE; HAZARD RATIO; HEART DEATH; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; NONALCOHOLIC FATTY LIVER; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; STANDARDIZATION; SURVIVAL;

ADULT; AGED; AGED, 80 AND OVER; CARDIOVASCULAR DISEASES; CHI-SQUARE DISTRIBUTION; COHORT STUDIES; FATTY LIVER; FEMALE; HUMANS; LIVER FUNCTION TESTS; MALE; MIDDLE AGED; NUTRITION SURVEYS; PROPORTIONAL HAZARDS MODELS; RISK; RISK FACTORS; UNITED STATES;

EID: 50649094716     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1111/j.1572-0241.2008.02034.x     Document Type: Article

References (29)

1. Browning JD, Szczepaniak LS, Dobbins R, et al. Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity. Hepatology 2004 40 : 1387 95.
2. Ryan CK, Johnson LA, Germin BI, et al. One hundred consecutive hepatic biopsies in the workup of living donors for right lobe liver transplantation. Liver Transpl 2002 8 : 1114 22.
3. Plan and operation of the Third National Health and Nutrition Examination Survey, 1988-94. National center for health statistics. Vital Health Stat 1994 1 : 1 407.
4. Prati D, Taioli E, Zanella A, et al. Updated definitions of healthy ranges for serum alanine aminotransferase levels. Ann Intern Med 2002 137 : 1 10.
5. Clark JM, Brancati FL, Diehl AM. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol 2003 98 : 960 7.
6. Daniel S, Ben-Menachem T, Vasudevan G, et al. Prospective evaluation of unexplained chronic liver transaminase abnormalities in asymptomatic and symptomatic patients. Am J Gastroenterol 1999 94 : 3010 4.
7. Skelly MM, James PD, Ryder SD. Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology. J Hepatol 2001 35 : 195 9.
8. Ratziu V, Giral P, Charlotte F, et al. Liver fibrosis in overweight patients. Gastroenterology 2000 118 : 1117 23.
9. Zelber-Sagi S, Nitzan-Kaluski D, Halpern Z, et al. Prevalence of primary non-alcoholic fatty liver disease in a population-based study and its association with biochemical and anthropometric measures. Liver Int 2006 26 : 856 63.
10. Jimba S, Nakagami T, Takahashi M, et al. Prevalence of non-alcoholic fatty liver disease and its association with impaired glucose metabolism in Japanese adults. Diabet Med 2005 22 : 1141 5.
11. Chen CH, Huang MH, Yang JC, et al. Prevalence and risk factors of nonalcoholic fatty liver disease in an adult population of taiwan: Metabolic significance of nonalcoholic fatty liver disease in nonobese adults. J Clin Gastroenterol 2006 40 : 745 52.
12. Yu AS, Keeffe EB. Elevated AST or ALT to nonalcoholic fatty liver disease: Accurate predictor of disease prevalence Am J Gastroenterol 2003 98 : 955 6.
13. Adams LA, Lymp JF, St Sauver J, et al. The natural history of nonalcoholic fatty liver disease: A population-based cohort study. Gastroenterology 2005 129 : 113 21.
14. Matteoni CA, Younossi ZM, Gramlich T, et al. Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity. Gastroenterology 1999 116 : 1413 9.
15. Woerle HJ, Pimenta WP, Meyer C, et al. Diagnostic and therapeutic implications of relationships between fasting, 2-hour postchallenge plasma glucose and hemoglobin a1c values. Arch Intern Med 2004 164 : 1627 32.
16. Hrebicek J, Janout V, Malincikova J, et al. Detection of insulin resistance by simple quantitative insulin sensitivity check index QUICKI for epidemiological assessment and prevention. J Clin Endocrinol Metab 2002 87 : 144 7.
17. Ruhl CE, Everhart JE. Joint effects of body weight and alcohol on elevated serum alanine aminotransferase in the United States population. Clin Gastroenterol Hepatol 2005 3 : 1260 8.
18. Anderson RN, Rosenberg HM. Age standardization of death rates: Implementation of the year 2000 standard. Natl Vital Stat Rep 1998 47 : 1 16, 20.
19. Ekstedt M, Franzen LE, Mathiesen UL, et al. Long-term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology 2006 44 : 865 73.
20. Tarantino G. Is NAFLD an incidentaloma Gastroenterology 2006 130 : 1014 5.
21. Ioannou GN, Weiss NS, Boyko EJ, et al. Elevated serum alanine aminotransferase activity and calculated risk of coronary heart disease in the United States. Hepatology 2006 43 : 1145 51.
22. Ruhl CE, Everhart JE. Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States. Gastroenterology 2003 124 : 71 9.
23. Villanova N, Moscatiello S, Ramilli S, et al. Endothelial dysfunction and cardiovascular risk profile in nonalcoholic fatty liver disease. Hepatology 2005 42 : 473 80.
24. Targher G, Bertolini L, Padovani R, et al. Relation of nonalcoholic hepatic steatosis to early carotid atherosclerosis in healthy men: Role of visceral fat accumulation. Diabetes Care 2004 27 : 2498 500.
25. Brea A, Mosquera D, Martin E, et al. Nonalcoholic fatty liver disease is associated with carotid atherosclerosis: A case-control study. Arterioscler Thromb Vasc Biol 2005 25 : 1045 50.
26. Volzke H, Robinson DM, Kleine V, et al. Hepatic steatosis is associated with an increased risk of carotid atherosclerosis. World J Gastroenterol 2005 11 : 1848 53.
27. Lin YC, Lo HM, Chen JD. Sonographic fatty liver, overweight and ischemic heart disease. World J Gastroenterol 2005 11 : 4838 42.
28. Targher G, Bertolini L, Poli F, et al. Nonalcoholic fatty liver disease and risk of future cardiovascular events among type 2 diabetic patients. Diabetes 2005 54 : 3541 6.
29. Kim HC, Nam CM, Jee SH, et al. Normal serum aminotransferase concentration and risk of mortality from liver diseases: Prospective cohort study. BMJ 2004 328 : 983.