-
1
-
-
0141491273
-
Hepatocellular carcinoma
-
DOI 10.1016/S0140-6736(03)14964-1
-
JM Llovet A Burroughs J Bruix 2003 Hepatocellular carcinoma Lancet 362 1907 1917 14667750 10.1016/S0140-6736(03)14964-1 (Pubitemid 37518510)
-
(2003)
Lancet
, vol.362
, Issue.9399
, pp. 1907-1917
-
-
Llovet, J.M.1
Burroughs, A.2
Bruix, J.3
-
2
-
-
63449111025
-
Evolution of systemic therapy of advanced hepatocellular carcinoma
-
19030192 10.3748/wjg.14.6437
-
T Yau P Chan R Epstein RT Poon 2008 Evolution of systemic therapy of advanced hepatocellular carcinoma World J Gastroenterol 14 6437 6441 19030192 10.3748/wjg.14.6437
-
(2008)
World J Gastroenterol
, vol.14
, pp. 6437-6441
-
-
Yau, T.1
Chan, P.2
Epstein, R.3
Poon, R.T.4
-
3
-
-
34250020201
-
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
-
DOI 10.1053/j.gastro.2007.04.061, PII S0016508507007998
-
HB El-Serag KL Rudolph 2007 Hepatocellular carcinoma: epidemiology and molecular carcinogenesis Gastroenterology 132 2557 2576 17570226 10.1053/j.gastro.2007.04.061 1:CAS:528:DC%2BD2sXnvFOgsrw%3D (Pubitemid 46890874)
-
(2007)
Gastroenterology
, vol.132
, Issue.7
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
4
-
-
33847036990
-
Strategies for silencing human disease using RNA interference
-
17304245 10.1038/nrg2006 1:CAS:528:DC%2BD2sXhslOgtrw%3D
-
DH Kim JJ Rossi 2007 Strategies for silencing human disease using RNA interference Nat Rev Genet 8 173 184 17304245 10.1038/nrg2006 1:CAS:528:DC%2BD2sXhslOgtrw%3D
-
(2007)
Nat Rev Genet
, vol.8
, pp. 173-184
-
-
Kim, D.H.1
Rossi, J.J.2
-
5
-
-
32644452086
-
RNA interference in cancer
-
DOI 10.1016/j.bioeng.2006.01.002, PII S1389034406000037
-
AL Gartel ES Kandel 2006 RNA interference in cancer Biomol Eng 23 17 34 16466964 10.1016/j.bioeng.2006.01.002 1:CAS:528:DC%2BD28XhsFOis7w%3D (Pubitemid 43243836)
-
(2006)
Biomolecular Engineering
, vol.23
, Issue.1
, pp. 17-34
-
-
Gartel, A.L.1
Kandel, E.S.2
-
6
-
-
58749104364
-
The promises and pitfalls of RNA-interference-based therapeutics
-
19158789 10.1038/nature07758 1:CAS:528:DC%2BD1MXotlOgsA%3D%3D
-
D Castanotto JJ Rossi 2009 The promises and pitfalls of RNA-interference-based therapeutics Nature 457 426 433 19158789 10.1038/nature07758 1:CAS:528:DC%2BD1MXotlOgsA%3D%3D
-
(2009)
Nature
, vol.457
, pp. 426-433
-
-
Castanotto, D.1
Rossi, J.J.2
-
7
-
-
0017903484
-
2 change the DNA helical structure
-
K Javaherian JF Liu JC Wang 1978 Nonhistone proteins HMG1 and HMG2 change the DNA helical structure Science 199 1345 1346 628842 10.1126/science.628842 1:CAS:528:DyaE1cXhsVOktr0%3D (Pubitemid 8292505)
-
(1978)
Science
, vol.199
, Issue.4335
, pp. 1345-1346
-
-
Javaherian, K.1
Liu, L.F.2
Wang, J.C.3
-
8
-
-
17144376810
-
High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
-
DOI 10.1038/nri1594
-
MT Lotze KJ Tracey 2005 High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal Nat Rev Immunol 5 331 342 15803152 10.1038/nri1594 1:CAS:528:DC%2BD2MXivVarsr8%3D (Pubitemid 40516158)
-
(2005)
Nature Reviews Immunology
, vol.5
, Issue.4
, pp. 331-342
-
-
Lotze, M.T.1
Tracey, K.J.2
-
9
-
-
0034753236
-
Dual roles for HMGB1: DNA binding and cytokine
-
DOI 10.1179/096805101101532792
-
CJ Czura H Wang KJ Tracey 2001 Dual roles for HMGB1: DNA binding and cytokine J Endotoxin Res 7 315 321 11717586 10.1177/09680519010070041401 1:CAS:528:DC%2BD3MXovVGjtb8%3D (Pubitemid 33041072)
-
(2001)
Journal of Endotoxin Research
, vol.7
, Issue.4
, pp. 315-321
-
-
Czura, C.J.1
Wang, H.2
Tracey, K.J.3
-
10
-
-
0141457280
-
Intracellular high mobility group B1 protein (HMGB1) represses HIV-1 LTR-directed transcription in a promoter- and cell-specific manner
-
DOI 10.1016/S0042-6822(03)00453-7
-
MH Naghavi P Nowak J Andersson, et al. 2003 Intracellular high mobility group B1 protein (HMGB1) represses HIV-1 LTR-directed transcription in a promoter- and cell-specific manner Virology 314 179 189 14517071 10.1016/S0042-6822(03)00453-7 1:CAS:528:DC%2BD3sXnsVWqs7w%3D (Pubitemid 37153308)
-
(2003)
Virology
, vol.314
, Issue.1
, pp. 179-189
-
-
Naghavi, M.H.1
Nowak, P.2
Andersson, J.3
Sonnerborg, A.4
Yang, H.5
Tracey, K.J.6
Vahlne, A.7
-
11
-
-
4444261780
-
HMGB1 is an endogenous immune adjuvant released by necrotic cells
-
DOI 10.1038/sj.embor.7400205
-
P Rovere-Querini A Capobianco P Scaffidi, et al. 2004 HMGB1 is an endogenous immune adjuvant released by necrotic cells EMBO Rep 5 825 830 15272298 10.1038/sj.embor.7400205 1:CAS:528:DC%2BD2cXmtFOhur8%3D (Pubitemid 39199174)
-
(2004)
EMBO Reports
, vol.5
, Issue.8
, pp. 825-830
-
-
Rovere-Querini, P.1
Capobianco, A.2
Scaffidi, P.3
Valentinis, B.4
Catalanotti, F.5
Giazzon, M.6
Dumitriu, I.E.7
Muller, S.8
Iannacone, M.9
Traversari, C.10
Bianchi, M.E.11
Manfredi, A.A.12
-
12
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
DOI 10.1038/nature00858
-
P Scaffidi T Misteli ME Bianchi 2002 Release of chromatin protein HMGB1 by necrotic cells triggers inflammation Nature 418 191 1955 12110890 10.1038/nature00858 1:CAS:528:DC%2BD38XltFGlsro%3D (Pubitemid 34773774)
-
(2002)
Nature
, vol.418
, Issue.6894
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
13
-
-
77949542302
-
The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival
-
19834494 10.1038/cdd.2009.149 1:CAS:528:DC%2BC3cXjt1Ogsbs%3D
-
R Kang D Tang NE Schapiro, et al. 2010 The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival Cell Death Differ 17 666 676 19834494 10.1038/cdd.2009.149 1:CAS:528:DC%2BC3cXjt1Ogsbs%3D
-
(2010)
Cell Death Differ
, vol.17
, pp. 666-676
-
-
Kang, R.1
Tang, D.2
Schapiro, N.E.3
-
14
-
-
64749107607
-
RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation
-
19292913 10.1186/1479-5876-7-17
-
L Sparvero D Asafu-Adje R Kang, et al. 2009 RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation J Transl Med 7 17 19292913 10.1186/1479-5876-7-17
-
(2009)
J Transl Med
, vol.7
, pp. 17
-
-
Sparvero, L.1
Asafu-Adje, D.2
Kang, R.3
-
15
-
-
77949656459
-
The expression of HMGB1 protein and its receptor RAGE in human malignant tumors
-
19876719 10.1007/s11010-009-0305-0 1:CAS:528:DC%2BC3cXjtVClsbs%3D
-
N Kostova S Zlateva I Ugrinova E Pasheva 2010 The expression of HMGB1 protein and its receptor RAGE in human malignant tumors Mol Cell Biochem 337 251 258 19876719 10.1007/s11010-009-0305-0 1:CAS:528:DC%2BC3cXjtVClsbs%3D
-
(2010)
Mol Cell Biochem
, vol.337
, pp. 251-258
-
-
Kostova, N.1
Zlateva, S.2
Ugrinova, I.3
Pasheva, E.4
-
16
-
-
33847656295
-
Expression of high mobility group box chromosomal protein-1 (HMGB-1) in gastric cancer
-
17352266 1:CAS:528:DC%2BD2sXjs1Wnt78%3D
-
H Akaike K Kono H Sugai, et al. 2007 Expression of high mobility group box chromosomal protein-1 (HMGB-1) in gastric cancer Anticancer Res 27 449 457 17352266 1:CAS:528:DC%2BD2sXjs1Wnt78%3D
-
(2007)
Anticancer Res
, vol.27
, pp. 449-457
-
-
Akaike, H.1
Kono, K.2
Sugai, H.3
-
17
-
-
0038487103
-
Co-expression of receptor for advanced glycation end products and the ligand amphoterin associates closely with metastasis of colorectal cancer
-
12579287
-
H Kuniyasu Y Chihara T Takahashi 2003 Co-expression of receptor for advanced glycation end products and the ligand amphoterin associates closely with metastasis of colorectal cancer Oncol Rep 10 445 448 12579287
-
(2003)
Oncol Rep
, vol.10
, pp. 445-448
-
-
Kuniyasu, H.1
Chihara, Y.2
Takahashi, T.3
-
18
-
-
78049302516
-
Elevated expression of HMGB1 in squamous-cell carcinoma of the head and neck and its clinical significance
-
20724142 10.1016/j.ejca.2010.07.016 1:CAS:528:DC%2BC3cXhtlCjsrnN
-
Y Liu C Xie X Zhang, et al. 2010 Elevated expression of HMGB1 in squamous-cell carcinoma of the head and neck and its clinical significance Eur J Cancer 46 3007 3015 20724142 10.1016/j.ejca.2010.07.016 1:CAS:528: DC%2BC3cXhtlCjsrnN
-
(2010)
Eur J Cancer
, vol.46
, pp. 3007-3015
-
-
Liu, Y.1
Xie, C.2
Zhang, X.3
-
19
-
-
42649090426
-
Serum high mobility group box chromosomal protein 1 is associated with clinicopathologic features in patients with hepatocellular carcinoma
-
18294942 10.1016/j.dld.2007.11.024 1:CAS:528:DC%2BD1cXnvVOrsbk%3D
-
BQ Cheng CQ Jia CT Liu, et al. 2008 Serum high mobility group box chromosomal protein 1 is associated with clinicopathologic features in patients with hepatocellular carcinoma Dig Liver Dis 40 446 452 18294942 10.1016/j.dld.2007.11.024 1:CAS:528:DC%2BD1cXnvVOrsbk%3D
-
(2008)
Dig Liver Dis
, vol.40
, pp. 446-452
-
-
Cheng, B.Q.1
Jia, C.Q.2
Liu, C.T.3
-
20
-
-
34249812086
-
Masquerader: High mobility group box-1 and cancer
-
DOI 10.1158/1078-0432.CCR-06-1953
-
JE Ellerman CK Brown M de Vera, et al. 2007 Masquerader: high mobility group box-1 and cancer Clin Cancer Res 13 2836 2848 17504981 10.1158/1078-0432.CCR-06-1953 1:CAS:528:DC%2BD2sXlt1Krsr4%3D (Pubitemid 46850704)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.10
, pp. 2836-2848
-
-
Ellerman, J.E.1
Brown, C.K.2
De Vera, M.3
Zeh, H.J.4
Billiar, T.5
Rubartelli, A.6
Lotze, M.T.7
-
21
-
-
0035710746
-
-ΔΔCT method
-
DOI 10.1006/meth.2001.1262
-
KJ Livak TD Schmittgen 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C (T)) method Methods 25 402 408 11846609 10.1006/meth.2001.1262 1:CAS:528:DC%2BD38XhtFelt7s%3D (Pubitemid 34164012)
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
22
-
-
77956196980
-
Effect of HMGB1-siRNA on proliferation and apoptosis of HepG2 cells
-
20510002 1:CAS:528:DC%2BC3cXhtFCis7%2FM
-
XC He XG Fan HB Liu RR Zhou HC Wang 2010 Effect of HMGB1-siRNA on proliferation and apoptosis of HepG2 cells Zhonghua Gan Zang Bing Za Zhi 18 361 365 20510002 1:CAS:528:DC%2BC3cXhtFCis7%2FM
-
(2010)
Zhonghua Gan Zang Bing Za Zhi
, vol.18
, pp. 361-365
-
-
He, X.C.1
Fan, X.G.2
Liu, H.B.3
Zhou, R.R.4
Wang, H.C.5
-
23
-
-
12644261425
-
Enhanced coexpression of thioredoxin and high mobility group protein 1 genes in human hepatocellular carcinoma and the possible association with decreased sensitivity to cisplatin
-
N Kawahara T Tanaka A Yokomizo, et al. 1996 Enhanced coexpression of thioredoxin and high mobility group protein 1 genes in human hepatocellular carcinoma and the possible association with decreased sensitivity to cisplatin Cancer Res 56 5330 5333 8968078 1:CAS:528:DyaK28Xntl2mtr0%3D (Pubitemid 27011357)
-
(1996)
Cancer Research
, vol.56
, Issue.23
, pp. 5330-5333
-
-
Kawahara, N.1
Tanaka, T.2
Yokomizo, A.3
Nanri, H.4
Ono, M.5
Wada, M.6
Kohno, K.7
Takenaka, K.8
Sugimachi, K.9
Kuwano, M.10
-
24
-
-
77953765714
-
Effect of HMGB1 on human hepatoma cell line-HepG2 proliferation
-
20543468 1:CAS:528:DC%2BC3cXhtFCiu7%2FE
-
X He X Fan R Zhou H Wang 2010 Effect of HMGB1 on human hepatoma cell line-HepG2 proliferation Zhong Nan Da Xue Xue Bao Yi Xue Ban 35 451 457 20543468 1:CAS:528:DC%2BC3cXhtFCiu7%2FE
-
(2010)
Zhong Nan da Xue Xue Bao Yi Xue Ban
, vol.35
, pp. 451-457
-
-
He, X.1
Fan, X.2
Zhou, R.3
Wang, H.4
-
25
-
-
28844498773
-
Molecular mechanisms of hepatic metastasis in colorectal cancer
-
DOI 10.1002/jso.20393
-
LR Rudmik AM Magliocco 2005 Molecular mechanisms of hepatic metastasis in colorectal cancer J Surg Oncol 92 347 359 16299807 10.1002/jso.20393 1:STN:280:DC%2BD2MnjtVChsw%3D%3D (Pubitemid 41779295)
-
(2005)
Journal of Surgical Oncology
, vol.92
, Issue.4
, pp. 347-359
-
-
Rudmik, L.R.1
Magliocco, A.M.2
-
26
-
-
68549112897
-
Mechanics, malignancy, and metastasis: The force journey of a tumor cell
-
19153673 10.1007/s10555-008-9173-4
-
S Kumar VM Weaver 2009 Mechanics, malignancy, and metastasis: the force journey of a tumor cell Cancer Metastasis Rev 28 113 127 19153673 10.1007/s10555-008-9173-4
-
(2009)
Cancer Metastasis Rev
, vol.28
, pp. 113-127
-
-
Kumar, S.1
Weaver, V.M.2
-
27
-
-
74549175673
-
High-mobility group box 1 and cancer
-
20123075 1:CAS:528:DC%2BC3cXpslWgug%3D%3D
-
D Tang R Kang HJ Zeh III MT Lotze 2010 High-mobility group box 1 and cancer Biochim Biophys Acta 1799 131 140 20123075 1:CAS:528: DC%2BC3cXpslWgug%3D%3D
-
(2010)
Biochim Biophys Acta
, vol.1799
, pp. 131-140
-
-
Tang, D.1
Kang, R.2
Zeh Iii, H.J.3
Lotze, M.T.4
-
28
-
-
1542380035
-
Involvement of Toll-like Receptors 2 and 4 in Cellular Activation by High Mobility Group Box 1 Protein
-
DOI 10.1074/jbc.M306793200
-
JS Park D Svetkauskaite Q He, et al. 2004 Involvement of TLR2 and TLR4 in cellular activation by high mobility group box 1 protein (HMGB1) J Biol Chem 279 7370 7377 14660645 10.1074/jbc.M306793200 1:CAS:528:DC%2BD2cXhsFaqurc%3D (Pubitemid 38294612)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.9
, pp. 7370-7377
-
-
Park, J.S.1
Svetkauskaite, D.2
He, Q.3
Kim, J.-Y.4
Strassheim, D.5
Ishizaka, A.6
Abraham, E.7
-
29
-
-
35349009132
-
Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-κB activation
-
DOI 10.1083/jcb.200704015
-
R Palumbo BG Galvez T Pusterla, et al. 2007 Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-kappaB activation J Cell Biol 179 33 40 17923528 10.1083/jcb.200704015 1:CAS:528:DC%2BD2sXhtFOntbzP (Pubitemid 47606681)
-
(2007)
Journal of Cell Biology
, vol.179
, Issue.1
, pp. 33-40
-
-
Palumbo, R.1
Galvez, B.G.2
Pusterla, T.3
De Marchis, F.4
Cossu, G.5
Marcu, K.B.6
Bianchi, M.E.7
-
30
-
-
0036717195
-
NF-κB, chemokine gene transcription and tumour growth
-
DOI 10.1038/nri887
-
A Richmond 2002 NF-kappa B, chemokine gene transcription and tumour growth Nat Rev Immunol 2 664 674 12209135 10.1038/nri887 1:CAS:528: DC%2BD38Xmslantrc%3D (Pubitemid 37328724)
-
(2002)
Nature Reviews Immunology
, vol.2
, Issue.9
, pp. 664-674
-
-
Richmond, A.1
-
31
-
-
3042579870
-
Evaluation of nuclear factor-κB, urokinase-type plasminogen activator, and HBx and their clinicopathological significance in hepatocellular carcinoma
-
DOI 10.1158/1078-0432.CCR-03-0574
-
CF Chan TO Yau DY Jin CM Wong ST Fan IO Ng 2004 Evaluation of nuclear factor-kappaB, urokinase-type plasminogen activator, and HBx and their clinicopathological significance in hepatocellular carcinoma Clin Cancer Res 10 4140 4149 15217951 10.1158/1078-0432.CCR-03-0574 1:CAS:528:DC%2BD2cXltFWmu70%3D (Pubitemid 38812494)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.12
, pp. 4140-4149
-
-
Chan, C.-F.1
Yau, T.-O.2
Jin, D.-Y.3
Wong, C.-M.4
Fan, S.-T.5
Ng, I.O.-L.6
-
32
-
-
68949184660
-
Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression
-
19472311 10.1002/hep.23008 1:CAS:528:DC%2BD1MXhtVKrtrrP
-
X Zhang S Liu T Hu S Liu Y He S Sun 2009 Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression Hepatology 50 490 499 19472311 10.1002/hep.23008 1:CAS:528:DC%2BD1MXhtVKrtrrP
-
(2009)
Hepatology
, vol.50
, pp. 490-499
-
-
Zhang, X.1
Liu, S.2
Hu, T.3
Liu, S.4
He, Y.5
Sun, S.6
-
33
-
-
33645242839
-
Expression of vascular endothelial growth factor-C in human hepatocellular carcinoma
-
16706827 10.1111/j.1440-1746.2005.04217.x 1:CAS:528:DC%2BD28XhtlajsLjK
-
R Yamaguchi H Yano O Nakashima, et al. 2006 Expression of vascular endothelial growth factor-C in human hepatocellular carcinoma J Gastroenterol Hepatol 21 152 160 16706827 10.1111/j.1440-1746.2005.04217.x 1:CAS:528:DC%2BD28XhtlajsLjK
-
(2006)
J Gastroenterol Hepatol
, vol.21
, pp. 152-160
-
-
Yamaguchi, R.1
Yano, H.2
Nakashima, O.3
-
34
-
-
59349116903
-
Knocking down barriers: Advances in siRNA delivery
-
19180106 10.1038/nrd2742 1:CAS:528:DC%2BD1MXhtFOqt70%3D
-
KA Whitehead R Langer DG Anderson 2009 Knocking down barriers: advances in siRNA delivery Nat Rev Drug Discov 8 129 138 19180106 10.1038/nrd2742 1:CAS:528:DC%2BD1MXhtFOqt70%3D
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 129-138
-
-
Whitehead, K.A.1
Langer, R.2
Anderson, D.G.3
|