Intracellular Na + concentration influences short-term plasticity of glutamate transporter-mediated currents in neocortical astrocytes

GLIA

Volumn 60, Issue 4, 2012, Pages 605-614

  Unichenko, Petr ^a   Myakhar, Olga ^b   Kirischuk, Sergei ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

EAAT; Extracellular GABA; GABA transporter; Paired pulse plasticity; SBFI

Indexed keywords

1 [2 (BENZHYDRYLIDENEAMINOOXY)ETHYL] 1,2,5,6 TETRAHYDRO 3 PYRIDINECARBOXYLIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID ANTAGONIST; BLOCKING AGENT; GLUTAMATE TRANSPORTER; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SODIUM ION; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ELECTROPHYSIOLOGY; BRAIN SLICE; CONTROLLED STUDY; ELECTROSTIMULATION; EVOKED RESPONSE; KINETICS; MOUSE; NEOCORTEX; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; ROOM TEMPERATURE; SIGNAL TRANSDUCTION;

ACTION POTENTIALS; AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ANIMALS, NEWBORN; ANISOLES; ASPARTIC ACID; ASTROCYTES; BENZOFURANS; BIOPHYSICS; CADMIUM CHLORIDE; CALCIUM CHANNEL BLOCKERS; ELECTRIC STIMULATION; ETHERS, CYCLIC; EXCITATORY AMINO ACID ANTAGONISTS; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; INTRACELLULAR FLUID; MICE; MICE, INBRED C57BL; NEOCORTEX; NEURONAL PLASTICITY; NIPECOTIC ACIDS; OXIMES; PATCH-CLAMP TECHNIQUES; RHODAMINES; SODIUM; SODIUM CHANNEL BLOCKERS; SYNAPTIC TRANSMISSION; TETRODOTOXIN;

EID: 84856726283     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22294     Document Type: Article

References (35)

1. Attwell D, Barbour B, Szatkowski M. 1993. Nonvesicular release of neurotransmitter. Neuron 11: 401-407.
2. Barbour B, Brew H, Attwell D. 1991. Electrogenic uptake of glutamate and aspartate into glial cells isolated from the salamander (Ambystoma) retina. J Physiol (Lond) 436: 169-193.
3. Bellamy TC, Ogden D. 2005. Short-term plasticity of Bergmann glial cell extrasynaptic currents during parallel fiber stimulation in rat cerebellum. Glia 52: 325-335.
4. Bennay M, Langer J, Meier SD, Kafitz KW, Rose CR. 2008. Sodium signals in cerebellar Purkinje neurons and Bergmann glial cells evoked by glutamatergic synaptic transmission. Glia 56: 1138-1149.
5. Bergles DE, Dzubay JA, Jahr CE. 1997. Glutamate transporter currents in bergmann glial cells follow the time course of extrasynaptic glutamate. Proc Natl Acad Sci USA 94: 14821-14825.
6. Bergles DE, Jahr CE. 1997. Synaptic activation of glutamate transporters in hippocampal astrocytes. Neuron 19: 1297-1308.
7. Billups B, Rossi D, Attwell D. 1996. Anion conductance behavior of the glutamate uptake carrier in salamander retinal glial cells. J Neurosci 16: 6722-6731.
8. + dynamics in mouse cortical astrocytes: Implications for cellular bioenergetics. Eur J Neurosci 12: 3843-3853.
9. Clark BA, Barbour B. 1997. Currents evoked in Bergmann glial cells by parallel fibre stimulation in rat cerebellar slices. J Physiol (Lond) 502: 335-350.
10. Danbolt NC, Chaudhry FA, Dehnes Y, Lehre KP, Levy LM, Ullensvang K, Storm-Mathisen J. 1998. Properties and localization of glutamate transporters. Prog Brain Res 116: 23-43.
11. Diamond JS, Jahr CE. 2000. Synaptically released glutamate does not overwhelm transporters on hippocampal astrocytes during high-frequency stimulation. J Neurophysiol 83: 2835-2843.
12. Feldmeyer D, Lubke J, Silver RA, Sakmann B. 2002. Synaptic connections between layer 4 spiny neuron-layer 2/3 pyramidal cell pairs in juvenile rat barrel cortex: Physiology and anatomy of interlaminar signalling within a cortical column. J Physiol (Lond) 538: 803-822.
13. Helmstaedter M, Staiger JF, Sakmann B, Feldmeyer D. 2008. Efficient recruitment of layer 2/3 interneurons by layer 4 input in single columns of rat somatosensory cortex. J Neurosci 28: 8273-8284.
14. Huang YH, Bergles DE. 2004. Glutamate transporters bring competition to the synapse. Curr Opin Neurobiol 14: 346-352.
15. Kinney GA. 2005. GAT-3 transporters regulate inhibition in the neocortex. J Neurophysiol 94: 4533-4537.
16. Kinney GA, Spain WJ. 2002. Synaptically evoked GABA transporter currents in neocortical glia. J Neurophysiol 88: 2899-2908.
17. Kirischuk S, Kettenmann H, Verkhratsky A. 2007. Membrane currents and cytoplasmic sodium transients generated by glutamate transport in Bergmann glial cells. Pflugers Arch 454: 245-252.
18. Kirmse K, Kirischuk S. 2006. Ambient GABA constrains the strength of GABAergic synapses at Cajal-Retzius cells in the developing visual cortex. J Neurosci 26: 4216-4227.
19. Langer J, Rose CR. 2009. Synaptically induced sodium signals in hippocampal astrocytes in situ. J Physiol (Lond) 587: 5859-5877.
20. +-dependent glutamate uptake. J Neurosci 18: 9620-9628.
21. Manita S, Suzuki T, Inoue M, Kudo Y, Miyakawa H. 2007. Paired-pulse ratio of synaptically induced transporter currents at hippocampal CA1 synapses is not related to release probability. Brain Res 1154: 71-79.
22. Minelli A, DeBiasi S, Brecha NC, Zuccarello LV, Conti F. 1996. GAT-3, a high-affinity GABA plasma membrane transporter, is localized to astrocytic processes, and it is not confined to the vicinity of GABAergic synapses in the cerebral cortex. J Neurosci 16: 6255-6264.
23. Nimmerjahn A, Kirchhoff F, Kerr JN, Helmchen F. 2004. Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo. Nat Methods 1: 31-37.
24. Okubo Y, Sekiya H, Namiki S, Sakamoto H, Iinuma S, Yamasaki M, Watanabe M, Hirose K, Iino M. 2010. Imaging extrasynaptic glutamate dynamics in the brain. Proc Natl Acad Sci USA 107: 6526-6531.
25. Otis TS, Jahr CE. 1998. Anion currents and predicted glutamate flux through a neuronal glutamate transporter. J Neurosci 18: 7099-7110.
26. Otis TS, Kavanaugh MP, Jahr CE. 1997. Postsynaptic glutamate transport at the climbing fiber-Purkinje cell synapse. Science 277: 1515-1518.
27. Richerson GB, Wu Y. 2003. Dynamic equilibrium of neurotransmitter transporters: Not just for reuptake anymore. J Neurophysiol 90: 1363-1374.
28. 2+ release in rat cerebellar Type-1 astrocytes. J Neurochem 100: 1188-1202.
29. Rose CR, Ransom BR. 1996. Intracellular sodium homeostasis in rat hippocampal astrocytes. J Physiol (Lond) 491: 291-305.
30. Rothstein JD, Martin L, Levey AI, Dykes Hoberg M, Jin L, Wu D, Nash N, Kuncl RW. 1994. Localization of neuronal and glial glutamate transporters. Neuron 13: 713-725.
31. Tzingounis AV, Wadiche JI. 2007. Glutamate transporters: Confining runaway excitation by shaping synaptic transmission. Nat Rev Neurosci 8: 935-947.
32. Wadiche JI, Tzingounis AV, Jahr CE. 2006. Intrinsic kinetics determine the time course of neuronal synaptic transporter currents. Proc Natl Acad Sci USA 103: 1083-1087.
33. Wu Y, Wang W, Diez-Sampedro A, Richerson GB. 2007. Nonvesicular inhibitory neurotransmission via reversal of the GABA transporter GAT-1. Neuron 56: 851-865.
34. Zerangue N, Kavanaugh MP. 1996. Flux coupling in a neuronal glutamate transporter. Nature 383: 634-637.
35. Zucker RS, Regehr WG. 2002. Short-term synaptic plasticity. Annu Rev Physiol 64: 355-405.