-
1
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
DOI 10.1056/NEJMoa043330
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus con-comitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352:987-996. (Pubitemid 40349501)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.B.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
2
-
-
51449124031
-
Cilengitide: An integrin-targeting arginine-glycine-aspartic acid peptide with promising activ-ity for glioblastoma multiforme
-
Reardon DA, Nabors LB, Stupp R, et al. Cilengitide: an integrin-targeting arginine-glycine-aspartic acid peptide with promising activ-ity for glioblastoma multiforme. Expert Opin Investig Drugs. 2008;17: 1225-1235.
-
(2008)
Expert Opin Investig Drugs.
, vol.17
, pp. 1225-1235
-
-
Reardon, D.A.1
Nabors, L.B.2
Stupp, R.3
-
3
-
-
70249128040
-
Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblas-toma: A multicenter phase II trial
-
Grossman SA, Ye X, Chamberlain M, et al. Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblas-toma: a multicenter phase II trial. J Clin Oncol. 2009;27:4155-4161.
-
(2009)
J Clin Oncol.
, vol.27
, pp. 4155-4161
-
-
Grossman, S.A.1
Ye, X.2
Chamberlain, M.3
-
4
-
-
78650138274
-
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adju-vant temozolomide in adults with newly diagnosed glioblastoma
-
Rosenfeld MR, Chamberlain MC, Grossman SA, et al. A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adju-vant temozolomide in adults with newly diagnosed glioblastoma. Neuro Oncol. 2010;12:1071-1077.
-
(2010)
Neuro Oncol.
, vol.12
, pp. 1071-1077
-
-
Rosenfeld, M.R.1
Chamberlain, M.C.2
Grossman, S.A.3
-
5
-
-
63849314514
-
Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblas-tomamultiforme
-
Mc Girt MJ, Than KD, Weingart JD, et al. Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblas- tomamultiforme. J Neurosurg. 2009;110:583-588.
-
(2009)
J Neurosurg.
, vol.110
, pp. 583-588
-
-
Mc Girt, M.J.1
Than, K.D.2
Weingart, J.D.3
-
6
-
-
34547148613
-
Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors
-
DOI 10.1073/pnas.0702916104
-
Kirson ED, Dbaly V, Tovarys F, et al. Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors. Proc Natl Acad Sci U S A. 2007;104:10152-10157. (Pubitemid 47175278)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.24
, pp. 10152-10157
-
-
Kirson, E.D.1
Dbaly, V.2
Tovarys, F.3
Vymazal, J.4
Soustiel, J.F.5
Itzhaki, A.6
Mordechovich, D.7
Steinberg-Shapira, S.8
Gurvich, Z.9
Schneiderman, R.10
Wasserman, Y.11
Salzberg, M.12
Ryffel, B.13
Goldsher, D.14
Dekel, E.15
Palti, Y.16
-
7
-
-
33644787355
-
Gliadel® wafer in initial surgery for malignant glioma: Long-term follow-up of a multicenter controlled trial
-
DOI 10.1007/s00701-005-0707-z
-
Westphal M, Ram Z, Riddle V, et al. Gliadel wafer in initial surgery for malignant glioma: long-term follow-up ofamulticenter controlled trial. Acta Neurochir (Wien). 2006;148:269-275; discussion 275. (Pubitemid 43341024)
-
(2006)
Acta Neurochirurgica
, vol.148
, Issue.3
, pp. 269-275
-
-
Westphal, M.1
Ram, Z.2
Riddle, V.3
Hilt, D.4
Bortey, E.5
-
8
-
-
33947547455
-
Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: A report by the cintredekin besudotox intraparenchymal study group
-
DOI 10.1200/JCO.2006.08.1117
-
Kunwar S, Prados MD, Chang SM, et al. Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrentmalignant glioma: a report by the Cintredekin Besudotox Intraparenchymal Study Group. J Clin Oncol. 2007;25:837-844. (Pubitemid 350002884)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.7
, pp. 837-844
-
-
Kunwar, S.1
Prados, M.D.2
Chang, S.M.3
Berger, M.S.4
Lang, F.F.5
Piepmeier, J.M.6
Sampson, J.H.7
Ram, Z.8
Gutin, P.H.9
Gibbons, R.D.10
Aldape, K.D.11
Croteau, D.J.12
Sherman, J.W.13
Puri, R.K.14
-
9
-
-
37349110365
-
Convection-enhanced delivery of cintredekin besudotox (interleukin-13- PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: Phase 1 study of final safety results
-
DOI 10.1227/01.neu.0000303199.77370.9e, PII 0000612320071100000017
-
Vogelbaum MA, Sampson JH, Kunwar S, et al. Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study offinal safety results. Neurosurgery. 2007;61:1031-1037; discussion 1037-1038. (Pubitemid 350306946)
-
(2007)
Neurosurgery
, vol.61
, Issue.5
, pp. 1031-1037
-
-
Vogelbaum, M.A.1
Sampson, J.H.2
Kunwar, S.3
Chang, S.M.4
Shaffrey, M.5
Asher, A.L.6
Lang, F.F.7
Croteau, D.8
Parker, K.9
Grahn, A.Y.10
Sherman, J.W.11
Husain, S.R.12
Puri, R.K.13
-
10
-
-
78149479157
-
Phase III randomized trial of CED of IL13-PE38QQR vs gliadel wafers for recurrent glioblastoma
-
Kunwar S, Chang S, Westphal M, et al. Phase III randomized trial of CED of IL13-PE38QQR vs gliadel wafers for recurrent glioblastoma. Neuro Oncol. 2010;12:871-881.
-
(2010)
Neuro Oncol.
, vol.12
, pp. 871-881
-
-
Kunwar, S.1
Chang, S.2
Westphal, M.3
-
11
-
-
0018167496
-
One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell
-
Yamaizumi M, Mekada E, Uchida T, et al. One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell. Cell. 1978;15: 245-250. (Pubitemid 9027527)
-
(1978)
Cell
, vol.15
, Issue.1
, pp. 245-250
-
-
Yamaizumi, M.1
Mekada, E.2
Uchida, T.3
Okada, Y.4
-
12
-
-
0020597630
-
Transferrin receptors in human tissues: Their distribution and possible clinical relevance
-
Gatter KC, Brown G, Trowbridge IS, et al. Transferrin receptors in human tissues: their distribution and possible clinical relevance. J Clin Pathol. 1983;36:539-545. (Pubitemid 13089724)
-
(1983)
Journal of Clinical Pathology
, vol.36
, Issue.5
, pp. 539-545
-
-
Gatter, K.C.1
Brown, G.2
Strowbridge, I.3
-
13
-
-
33846794839
-
Inhibition of transferrin iron release increases in vitro drug carrier efficacy
-
DOI 10.1016/j.jconrel.2006.12.001, PII S0168365906006973
-
Lao BJ, Tsai WL, Mashayekhi F, et al. Inhibition of transferrin iron release increases in vitro drug carrier efficacy. J Control Release. 2007;117:403-412. (Pubitemid 46216586)
-
(2007)
Journal of Controlled Release
, vol.117
, Issue.3
, pp. 403-412
-
-
Lao, B.J.1
Tsai, W.-L.P.2
Mashayekhi, F.3
Pham, E.A.4
Mason, A.B.5
Kamei, D.T.6
-
14
-
-
58149216739
-
Molecular targeting with recombinant cytotoxins for the treatment of brain tumors
-
Debinski W. Molecular targeting with recombinant cytotoxins for the treatment of brain tumors. Drug Dev Res. 2008;69:407-414.
-
(2008)
Drug Dev Res.
, vol.69
, pp. 407-414
-
-
Debinski, W.1
-
15
-
-
80053555147
-
Targeted toxins for glio-blastoma multiforme: Pre-clinical studies and clinical implementation
-
[published online ahead ofprint June 27 2011]
-
Candolfi M, Kroeger KM, Xiong W, et al. Targeted toxins for glio-blastoma multiforme: pre-clinical studies and clinical implementation. Anticancer Agents Med Chem. [published online ahead ofprint June 27, 2011].
-
Anticancer Agents Med Chem
-
-
Candolfi, M.1
Kroeger, K.M.2
Xiong, W.3
-
16
-
-
70450253409
-
Intracranial elimination ofhuman-glioblastoma brain tumors in nude rats using the bispecific ligand-directed toxin, DTEGF13 and convection enhanced delivery
-
Oh S, Ohlfest JR, Todhunter DA, et al. Intracranial elimination ofhuman-glioblastoma brain tumors in nude rats using the bispecific ligand-directed toxin, DTEGF13 and convection enhanced delivery J Neurooncol. 2009; 95:331-342.
-
(2009)
J Neurooncol.
, vol.95
, pp. 331-342
-
-
Oh, S.1
Ohlfest, J.R.2
Todhunter, D.A.3
-
17
-
-
0034619328
-
Neural stem cells display extensive tropism for pathology in adult brain: Evidence from intracra-nial gliomas
-
Aboody KS, Brown A, Rainov NG, et al. Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracra-nial gliomas. Proc Natl Acad Sci US A. 2000;97:12846-12851.
-
(2000)
Proc Natl Acad Sci US A.
, vol.97
, pp. 12846-12851
-
-
Aboody, K.S.1
Brown, A.2
Rainov, N.G.3
-
18
-
-
78650744910
-
Combined treatment oftumor-tropic human neural stem cells containing the CD suicide gene effectively targets brain tumors provoking amildimmuneresponse
-
Lee SJ, Kim Y, Jo MY, et al. Combined treatment oftumor-tropic human neural stem cells containing the CD suicide gene effectively targets brain tumors provoking amildimmuneresponse. Oncol Rep. 2011;25:63-68
-
(2011)
Oncol Rep.
, vol.25
, pp. 63-68
-
-
Lee, S.J.1
Kim, Y.2
Jo, M.Y.3
-
20
-
-
0029552093
-
Human astrocytoma cells express a unique chloride current
-
Ullrich N, Gillespie GY, Sontheimer H. Human astrocytoma cells ex-press a unique chloride current. Neuroreport. 1995;7:343-347. (Pubitemid 26078186)
-
(1995)
NeuroReport
, vol.7
, Issue.1
, pp. 343-347
-
-
Ullrich, N.1
Gillespie, G.Y.2
Sontheimer, H.3
-
21
-
-
0029975238
-
Human astrocytoma cells express a unique chloride current
-
Ullrich N, Gillespie GY, Sontheimer H. Human astrocytoma cells ex-press a unique chloride current. Neuroreport. 1996;7:1020-1024. (Pubitemid 26194473)
-
(1996)
NeuroReport
, vol.7
, Issue.5
, pp. 1020-1024
-
-
Ullrich, N.1
Gillespie, G.Y.2
Sontheimer, H.3
-
22
-
-
0032509803
-
Expression of voltage-activated chloride currents in acute slices of human gliomas
-
DOI 10.1016/S0306-4522(97)00456-9, PII S0306452297004569
-
Ullrich N, Bordey A, Gillespie GY, et al. Expression ofvoltage-activated chloride currents in acute slices of human gliomas. Neuroscience. 1998; 83:1161-1173. (Pubitemid 28114208)
-
(1998)
Neuroscience
, vol.83
, Issue.4
, pp. 1161-1173
-
-
Ullrich, N.1
Bordey, A.2
Gillespie, G.Y.3
Sontheimer, H.4
-
23
-
-
0032211350
-
Use of chlorotoxin for targetingofprimarybraintumors
-
Soroceanu L, Gillespie Y, Khazaeli MB, et al. Use of chlorotoxin for targetingofprimarybraintumors. Cancer Res. 1998;58:4871-4879.
-
(1998)
Cancer Res.
, vol.58
, pp. 4871-4879
-
-
Soroceanu, L.1
Gillespie, Y.2
Khazaeli, M.B.3
-
24
-
-
0035983279
-
Chlorotoxin, a scorpion-derived peptide, specifically binds to gliomas and tumors of neuroectodermal origin
-
DOI 10.1002/glia.10083
-
Lyons SA, O'Neal J, Sontheimer H. Chlorotoxin, a scorpion-derived peptide, specifically binds to gliomas and tumors of neuroectodermal origin. Glia. 2002;39:162-173. (Pubitemid 34817056)
-
(2002)
GLIA
, vol.39
, Issue.2
, pp. 162-173
-
-
Lyons, S.A.1
O'Neal, J.2
Sontheimer, H.3
-
25
-
-
77649248564
-
Potent pleiotropic anti-angiogenic effects of TM601, a synthetic chlorotoxin peptide
-
Jacoby DB, Dyskin E, Yalcin M, et al. Potent pleiotropic anti-angiogenic effects of TM601, a synthetic chlorotoxin peptide. Anticancer Res. 2010;30:39-46.
-
(2010)
Anticancer Res.
, vol.30
, pp. 39-46
-
-
Jacoby, D.B.1
Dyskin, E.2
Yalcin, M.3
-
26
-
-
33747059059
-
Phase I single-dose study of intracavitary-administered iodine-131-TM-601 in adults with recurrent high-grade glioma
-
DOI 10.1200/JCO.2005.05.4569
-
Mamelak AN, Rosenfeld S, Bucholz R, et al. Phase I single-dose study of intracavitary-administered iodine-131-TM-601 in adults with recur-rent high-grade glioma. J Clin Oncol. 2006;24:3644-3650. (Pubitemid 46630539)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.22
, pp. 3644-3650
-
-
Mamelak, A.N.1
Rosenfeld, S.2
Bucholz, R.3
Raubitschek, A.4
Nabors, L.B.5
Fiveash, J.B.6
Shen, S.7
Khazaeli, M.B.8
Colcher, D.9
Liu, A.10
Osman, M.11
Guthrie, B.12
Schade-Bijur, S.13
Hablitz, D.M.14
Alvarez, V.L.15
Gonda, M.A.16
-
30
-
-
34547110147
-
Tumor paint: A chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci
-
DOI 10.1158/0008-5472.CAN-06-3948
-
Veiseh M, Gabikian P, Bahrami SB, et al. Tumor paint: a chlorotoxin: Cy5.5 bioconjugate for intraoperative visualization of cancer foci. Cancer Res. 2007;67:6882-6888. (Pubitemid 47105535)
-
(2007)
Cancer Research
, vol.67
, Issue.14
, pp. 6882-6888
-
-
Veiseh, M.1
Gabikian, P.2
Bahrami, S.-B.3
Veiseh, O.4
Zhang, M.5
Hackman, R.C.6
Ravanpay, A.C.7
Stroud, M.R.8
Kusuma, Y.9
Hansen, S.J.10
Kwok, D.11
Munoz, N.M.12
Sze, R.W.13
Grady, W.M.14
Greenberg, N.M.15
Ellenbogen, R.G.16
Olson, J.M.17
-
31
-
-
0034433453
-
Fluorescence-guided resection of glioblastoma multiforme by using 5-aminolevulinic acid-induced porphyrins: A prospective study in 52 consecutive patients
-
Stummer W, Novotny A, Stepp H, et al. Fluorescence-guided resection of glioblastoma multiforme by using 5-aminolevulinic acid-induced porphyrins: a prospective study in 52 consecutive patients. JNeurosurg. 2000;93:1003-1013. (Pubitemid 32800611)
-
(2000)
Journal of Neurosurgery
, vol.93
, Issue.6
, pp. 1003-1013
-
-
Stummer, W.1
Novotny, A.2
Stepp, H.3
Goetz, C.4
Bise, K.5
Reulen, H.J.6
-
32
-
-
60549111057
-
Resection and survival in glioblastoma multiforme: An RTOG recursive partitioning analysis of ALA study patients
-
Pichlmeier U, Bink A, Schackert G, et al. Resection and survival in glioblastoma multiforme: an RTOG recursive partitioning analysis of ALA study patients. Neuro Oncol. 2008;10:1025-1034.
-
(2008)
Neuro Oncol.
, vol.10
, pp. 1025-1034
-
-
Pichlmeier, U.1
Bink, A.2
Schackert, G.3
-
33
-
-
41049112174
-
In vivo MRI detection of gliomas by chlorotoxin-conjugated superparamagnetic nanoprobes
-
DOI 10.1002/smll.200700784
-
Sun C, Veiseh O, Gunn J, et al. In vivo MRI detection of gliomas by chlorotoxin-conjugated superparamagnetic nanoprobes. Small. 2008;4: 372-379. (Pubitemid 351421268)
-
(2008)
Small
, vol.4
, Issue.3
, pp. 372-379
-
-
Sun, C.1
Veiseh, O.2
Gunn, J.3
Fang, C.4
Hansen, S.5
Lee, D.6
Sze, R.7
Ellenbogen, R.G.8
Olson, J.9
Zhang, M.10
-
34
-
-
56549089703
-
Tumor-targeted drug delivery and MRI contrast enhancement by chlorotoxin-conjugated iron oxide nanoparti-cles
-
Sun C, Fang C, Stephen Z, et al. Tumor-targeted drug delivery and MRI contrast enhancement by chlorotoxin-conjugated iron oxide nanoparti-cles. Nanomedicine (Lond). 2008;3:495-505.
-
(2008)
Nanomedicine (Lond).
, vol.3
, pp. 495-505
-
-
Sun, C.1
Fang, C.2
Stephen, Z.3
-
35
-
-
59449110643
-
Inhibition of tumor-cell inva-sion with chlorotoxin-bound superparamagnetic nanoparticles
-
Veiseh O, Gunn JW, Kievit FM, et al. Inhibition of tumor-cell inva-sion with chlorotoxin-bound superparamagnetic nanoparticles. Small. 2009;5:256-264.
-
(2009)
Small.
, vol.5
, pp. 256-264
-
-
Veiseh, O.1
Gunn, J.W.2
Kievit, F.M.3
-
36
-
-
0023413505
-
Electrical stimulation ofrepair ofbone
-
Bassett CA. Electrical stimulation ofrepair ofbone. JBone Joint Surg Am. 1987;69:1110-1111.
-
(1987)
JBone Joint Surg Am.
, vol.69
, pp. 1110-1111
-
-
Bassett, C.A.1
-
37
-
-
2342593369
-
Disruption of Cancer Cell Replication by Alternating Electric Fields
-
DOI 10.1158/0008-5472.CAN-04-0083
-
Kirson ED, Gurvich Z, Schneiderman R, et al. Disruption of cancer cell replication by alternating electric fields. Cancer Res. 2004;64: 3288-3295. (Pubitemid 38581435)
-
(2004)
Cancer Research
, vol.64
, Issue.9
, pp. 3288-3295
-
-
Kirson, E.D.1
Gurvich, Z.2
Schneiderman, R.3
Dekel, E.4
Itzhaki, A.5
Wasserman, Y.6
Schatzberger, R.7
Palti, Y.8
-
38
-
-
0026643589
-
Effects ofvinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis
-
Jordan MA, Thrower D, Wilson L. Effects ofvinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis. J Cell Sci. 1992;102(Pt 3):401-416.
-
(1992)
J Cell Sci.
, vol.102
, Issue.PART 3
, pp. 401-416
-
-
Jordan, M.A.1
Thrower, D.2
Wilson, L.3
-
40
-
-
0034000931
-
Computerized video time-lapse microscopy studies of ionizing radiation- induced rapid-interphase and mitosis-related apoptosis in lymphoid cells
-
Endlich B, Radford IR, Forrester HB, et al. Computerized video time-lapse microscopy studies of ionizing radiation-induced rapid-interphase and mitosis-related apoptosis in lymphoid cells. Radiat Res. 2000;153: 36-48. (Pubitemid 30117082)
-
(2000)
Radiation Research
, vol.153
, Issue.1
, pp. 36-48
-
-
Endlich, B.1
Radford, I.R.2
Forrester, H.B.3
Dewey, W.C.4
-
41
-
-
0032767387
-
Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials
-
Wong ET, Hess KR, Gleason MJ, et al. Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials. J Clin Oncol. 1999;17:2572-2578. (Pubitemid 29368260)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.8
, pp. 2572-2578
-
-
Wong, E.T.1
Hess, K.R.2
Gleason, M.J.3
Jaeckle, K.A.4
Kyritsis, A.P.5
Prados, M.D.6
Levin, V.A.7
Yung, W.K.A.8
-
43
-
-
77956698654
-
A prospective, randomized, open-label, phase III clinical trial of Novo TTF-100Aversus best standard of care chemotherapy in patients with recurrent glioblastoma
-
[18
-
Stupp RKA, Engelhard H, Heidecke V, et al. A prospective, randomized, open-label, phase III clinical trial of Novo TTF-100Aversus best standard of care chemotherapy in patients with recurrent glioblastoma. J Clin Oncol. 2010;28[18 suppl]:LBA2007.
-
(2010)
J Clin Oncol.
, vol.28
, Issue.SUPPL.
-
-
Rka, S.1
Engelhard, H.2
Heidecke, V.3
-
44
-
-
70350142397
-
Patterns ofrelapse and prognosis after bevacizumab failure in recurrent glioblastoma
-
Iwamoto FM, Abrey LE, Beal K, et al. Patterns ofrelapse and prognosis after bevacizumab failure in recurrent glioblastoma. Neurology. 2009;73: 1200-1206.
-
(2009)
Neurology.
, vol.73
, pp. 1200-1206
-
-
Iwamoto, F.M.1
Abrey, L.E.2
Beal, K.3
-
45
-
-
65249134902
-
Chemotherapeutic treat-ment efficacy and sensitivity are increased by adjuvant alternating elec-tric fields (TTFields)
-
Kirson ED, Schneiderman RS, Dbaly V, et al. Chemotherapeutic treat-ment efficacy and sensitivity are increased by adjuvant alternating elec-tric fields (TTFields). BMCMed Phys. 2009;9:1
-
(2009)
BMCMed Phys.
, vol.9
, pp. 1
-
-
Kirson, E.D.1
Schneiderman, R.S.2
Dbaly, V.3
|