The role of p73 G4C14-to-A4T14 polymorphism in the susceptibility to cervical cancer

DNA and Cell Biology

Volumn 31, Issue 2, 2012, Pages 224-229

  Craveiro, Rogéria ^a   Bravo, Isabel ^a   Catarino, Raquel ^a   Teixeira, Ana Luisa ^a   Sousa, Hugo ^a   Pereira, Deolinda ^a   Pereira, Helena ^a   Rui, Medeiros ^a,b,c,d  

^a PORTUGUESE ONCOLOGY INSTITUTE   (Portugal)

^b UNIVERSIDADE FERNANDO PESSOA   (Portugal)

^c LPCC   (Portugal)

^d UNIVERSITY OF PORTO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P73;

ADULT; ARTICLE; CANCER SUSCEPTIBILITY; CARCINOGENESIS; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; HUMAN; MAJOR CLINICAL STUDY; PARITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; UTERINE CERVIX CANCER; WESTERN EUROPE;

ADULT; AGED; AT RICH SEQUENCE; BASE COMPOSITION; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CERVICAL INTRAEPITHELIAL NEOPLASIA; DNA-BINDING PROTEINS; FEMALE; GC RICH SEQUENCE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MIDDLE AGED; NEOPLASM GRADING; NUCLEAR PROTEINS; POLYMORPHISM, GENETIC; TUMOR SUPPRESSOR PROTEINS; UTERINE CERVICAL NEOPLASMS;

HUMAN PAPILLOMAVIRUS;

EID: 84856698297     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2011.1294     Document Type: Article

References (80)

1. Balsitis, S.J., Sage, J., Duensing, S., Münger, K., Jacks, T., and Lambert, P.F. (2003). Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRbindependent effects of E7 in vivo. Mol Cell Biol 23, 9094-9103. (Pubitemid 37499799)
2. Brooks, L.A., Sullivan, A., O'Nions, J., Bell, A., Dunne, B., Tidy, J.A., Evans, D.J., Osin, P., Vousden, K.H., Gusterson, B., Farrell, P.J., Storey, A., Gasco, M., Sakai, T., and Crook, T. (2002). E7 proteins from oncogenic human papillomavirus types transactivate p73: role in cervical intraepithelial neoplasia. Br J Cancer 86, 263-268. (Pubitemid 34185156)
3. Cai, Y.C., Yang, G.Y., Nie, Y., Wang, L.-D., Zhao, X., Song, Y.L., Seril, D.N., Liao, J., Xing, E.P., and Yang, C.S. (2000). Molecular alterations of p73 in human esophageal squamous cell carcinomas: loss of heterozygosity occurs frequently; loss of imprinting and elevation of p73 expression may be related to defective p53. Carcinogenesis 21, 683-689. (Pubitemid 30214025)
4. Catarino, R., Matos, A., Pinto, D., Pereira, D., Craveiro, R., Vasconcelos, A., Lopes, C., and Medeiros, R. (2005). Increased risk of cervical cancer associated with cyclin D1 gene A870G polymorphism. Cancer Genet Cytogenet 160, 49-54. (Pubitemid 40798136)
5. Catarino, R.J., Breda, E., Coelho, V., Pinto, D., Sousa, H., Lopes, C., and Medeiros, R. (2006). Association of the A870G cyclin D1 gene polymorphism with genetic susceptibility to nasopharyngeal carcinoma. Head Neck 28, 603-608. (Pubitemid 44025108)
6. Chen, X., Sturgis, E.M., Etzel, C.J., Wei, Q., and Li, G. (2008). p73 G4C14-to-A4T14 polymorphism and risk of human papillomavirus assoaciated squamous cell carcinoma of the oropharynx in never smokers and never drinkers. Cancer 113, 3307-3314.
7. Cheung, A., Tsun, K.L, Ng, K.M., Szeto, E., Siu, M., Wong, E., and Ngan, H. (2010). P634A4 and TAp73 immunocytochemistry in liquid-based cervical cytology-potential biomarkers for diagnosis and progress prediction of cervical neoplasia. Mod Pathol 23, 559-566.
8. Chu, T.Y., Shen, C.Y., Lee, H.S., and Liu H.S. (1999). Monoclonality and surface lesion-specific microsatellite alterations in premalignant and malignant neoplasia of uterine cervix: a local field effect of genomic instability and clonal evolution. Genes Chrom Cancer 24, 127-134.
9. Coelho, A.,Matos, A., Catarino, R., Pinto D., Pereira, D., Lopes, C., and Medeiros, R. (2005). Protective role of the polymorphism CCR2-64I in the progression from squamous intraepithelial lesions to invasive cervical carcinoma. Gynecol Oncol 96, 760-764. (Pubitemid 40255498)
10. Costa, S., Medeiros, R., Vasconcelos, A., Pinto, D., Lopes, C. (2002). A slow acetylator genotype associated with an increased of advanced cervical cancer. J Cancer Res Clin Oncol 128, 678-682. (Pubitemid 35435843)
11. Craveiro, R., Costa, S., Pinto, D., Salgado, L., Carvalho, L., Castro, C., Bravo, I., Lopes, C., Silva, I., and Medeiros, R. (2004). TP73 alterations in cervical carcinoma. Cancer Genet Cytogenet 150, 116-121. (Pubitemid 38456852)
12. De Feo, E., Persiani, R., La Greca, A., Amore, R., Arzani, D., Rausei, S., D'Ugo, D., Magistrelli, P., van Duijn, C.M., Ricciardi, G., and Boccia, S. (2009). A case-control study on the effect of p53 and p73 gene polymorphisms on gastric cancer risk and progression. Mutat Res 675, 60-65.
13. De Villiers, E.-M. (2003). Relationship between steroid hormone contraceptives and HPV, cervical intraepithelial neoplasia, and cervical carcinoma. Int J Cancer 103, 705-708. (Pubitemid 36110224)
14. Duarte, I., Santos, A., Sousa, H., Catarino, R., Pinto, D., Matos, A., Pereira, D., Moutinho, J., Canedo, P., Machado, J.C., and Medeiros, R. (2005). G-308A TNF-a polymorphism is associated with an increased risk of invasive cervical cancer. Biochem Biophys Res Commun 334, 588-592. (Pubitemid 40982407)
15. Ferreira, P.M., Catarino, R., Pereira, D., Matos, A., Pinto, D., Coelho, A., Lopes, C., and Medeiros, R. (2006). Cervical cancer and CYP2E1 polymorphisms: implications for molecular epidemiology. Eur J Clin Pharmacol 62, 15-21. (Pubitemid 43106311)
16. Fiedler, M., Müller-Holzner, E., Viertler, H.P., Widschwendter, A., Laich, A., Pfister, G., Spoden, G.A., Jansen-Dürr, P., and Zwerschke, W. (2004). High level HPV-16E7 oncoprotein expression correlates with reduced pRb-levels in cervical biopsies. FASEB J 18, 1120-1122. (Pubitemid 39561543)
17. Han, S., Semba, S., Abe, T., Makino, N., Furukawa, T., Fukushige, S., Takahashi, H., Sakurada, A., Sato, M., Shiiba, K., Matsuno, S., Nimura, Y., Nakagawara, A., and Horii, A. (1999). Infrequent somatic mutations of the p73 gene in various human cancers. Eur J Surg Oncol 25, 194-198. (Pubitemid 29182464)
18. Hu, Z., Miao, X., Ma, H., Tan, W., Wang, X., Lu, D., Wei, Q., Lin, D., and Shen, H. (2005). Dinucleotide polymorphism of p73 gene is associated with a reduced risk of lung cancer in a Chinese population. Int J Cancer 114, 455-460. (Pubitemid 40279969)
19. Jeon, S., Allen-Hoffmann, B.L., and Lambert, P.F. (1995). Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells. J Virol 69, 2989-2997.
20. Ji, X., Sturgis, E.M., Zhao, C., Etzel, C.J., Wei, Q., and Li, G. (2009). Association of G4C14-to-A4T14 polymorphism with human papillomavirus type 16 status in squamous cell carcinoma of the head and neck in non-hispanic whites. Cancer 115, 1660-1668.
21. Jin, L., Qi, M., Chen, D.Z., Anderson, A., Yang, G.Y., Arbeit, J.M., and Auborn, K.J. (1999). Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice. Cancer Res 59, 3991-3997. (Pubitemid 29393567)
22. Koushik, A., Ghosh, A., Duarte-Franco, E., Forest, P., Voyer, H., Matlashewski, G., Coutlée, F., and Franco, E.L. (2005). Biomarkers of Cervical Cancer Risk (BCCR) Study Team. The p53 codon 72 polymorphism and risk of high-grade cervical intraepithelial neoplasia. Cancer Detect Prev 29, 307-316. (Pubitemid 41267288)
23. Lee, K.E., Hong, Y.S., Kim, B.G., Kim, N.Y., Lee, K.M., Kwak, J.Y., and Roh, M.S. (2010). p73 G4C14 to A4T14 polymorphism is associated with colorectal cancer risk and survival. World J Gastroenterol 16, 4448-4454.
24. Li, G., Sturgis, E.M., Wang, L.-E., Chamberlain, R.M., Amos, C.I., Spitz, M.R., El-Naggar, A.K., Hong, W.K., and Wei, Q. (2004a). Association of a p73 exon 2 G4C14-to -A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck. Carcinogenesis 25, 1911-1916. (Pubitemid 39405910)
25. Li, G., Wang, L.E., Chamberlain, R.M., Amos, C.I., Spitz, M.R., and Wei, Q. (2004b). p73 G4C14-to -A4T14 polymorphism and risk of lung cancer. Cancer Res 64, 6863-6866. (Pubitemid 39330992)
26. Liu, S.S., Leung, R.C., Chan, K.Y., Chiu, P.M., Cheung, A.N., Tam, K.F., Ng, T.Y., Wong, L.C., and Ngan, H.Y. (2004). p73 expression is associated with the cellular radiosensitivity in cervical cancer after radiotherapy. Clin Cancer Res 10, 3309-3316. (Pubitemid 38685435)
27. Mai, M., Yokomizo, A., Qian, C., Yang, P., Tindall, D.J., Smith, D.I., and Liu, W. (1998). Activation of p73 silent allele in lung cancer. Cancer Res 58, 2347-2349. (Pubitemid 28252692)
28. Marin, M.C., Jost, C.A., Irwin, M.S., DeCaprio, J.A., Caput, D., and Kaelin, W.G., Jr. (1998). Viral oncoproteins discriminate between p53 and the p53 homolog p73. Mol Cell Biol 18, 6316-6324. (Pubitemid 28500522)
29. Balsitis, S.J., Sage, J., Duensing, S., Münger, K., Jacks, T., and Lambert, P.F. (2003). Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRbindependent effects of E7 in vivo. Mol Cell Biol 23, 9094-9103. (Pubitemid 37499799)
30. Brooks, L.A., Sullivan, A., O'Nions, J., Bell, A., Dunne, B., Tidy, J.A., Evans, D.J., Osin, P., Vousden, K.H., Gusterson, B., Farrell, P.J., Storey, A., Gasco, M., Sakai, T., and Crook, T. (2002). E7 proteins from oncogenic human papillomavirus types transactivate p73: role in cervical intraepithelial neoplasia. Br J Cancer 86, 263-268. (Pubitemid 34185156)
31. Cai, Y.C., Yang, G.Y., Nie, Y., Wang, L.-D., Zhao, X., Song, Y.L., Seril, D.N., Liao, J., Xing, E.P., and Yang, C.S. (2000). Molecular alterations of p73 in human esophageal squamous cell carcinomas: loss of heterozygosity occurs frequently; loss of imprinting and elevation of p73 expression may be related to defective p53. Carcinogenesis 21, 683-689. (Pubitemid 30214025)
32. Catarino, R., Matos, A., Pinto, D., Pereira, D., Craveiro, R., Vasconcelos, A., Lopes, C., and Medeiros, R. (2005). Increased risk of cervical cancer associated with cyclin D1 gene A870G polymorphism. Cancer Genet Cytogenet 160, 49-54. (Pubitemid 40798136)
33. Catarino, R.J., Breda, E., Coelho, V., Pinto, D., Sousa, H., Lopes, C., and Medeiros, R. (2006). Association of the A870G cyclin D1 gene polymorphism with genetic susceptibility to nasopharyngeal carcinoma. Head Neck 28, 603-608. (Pubitemid 44025108)
34. Chen, X., Sturgis, E.M., Etzel, C.J., Wei, Q., and Li, G. (2008). p73 G4C14-to-A4T14 polymorphism and risk of human papillomavirus assoaciated squamous cell carcinoma of the oropharynx in never smokers and never drinkers. Cancer 113, 3307-3314.
35. Cheung, A., Tsun, K.L, Ng, K.M., Szeto, E., Siu, M., Wong, E., and Ngan, H. (2010). P634A4 and TAp73 immunocytochemistry in liquid-based cervical cytology-potential biomarkers for diagnosis and progress prediction of cervical neoplasia. Mod Pathol 23, 559-566.
36. Chu, T.Y., Shen, C.Y., Lee, H.S., and Liu H.S. (1999). Monoclonality and surface lesion-specific microsatellite alterations in premalignant and malignant neoplasia of uterine cervix: a local field effect of genomic instability and clonal evolution. Genes Chrom Cancer 24, 127-134.
37. Coelho, A.,Matos, A., Catarino, R., Pinto D., Pereira, D., Lopes, C., and Medeiros, R. (2005). Protective role of the polymorphism CCR2-64I in the progression from squamous intraepithelial lesions to invasive cervical carcinoma. Gynecol Oncol 96, 760-764. (Pubitemid 40255498)
38. Costa, S., Medeiros, R., Vasconcelos, A., Pinto, D., Lopes, C. (2002). A slow acetylator genotype associated with an increased of advanced cervical cancer. J Cancer Res Clin Oncol 128, 678-682. (Pubitemid 35435843)
39. Craveiro, R., Costa, S., Pinto, D., Salgado, L., Carvalho, L., Castro, C., Bravo, I., Lopes, C., Silva, I., and Medeiros, R. (2004). TP73 alterations in cervical carcinoma. Cancer Genet Cytogenet 150, 116-121. (Pubitemid 38456852)
40. De Feo, E., Persiani, R., La Greca, A., Amore, R., Arzani, D., Rausei, S., D'Ugo, D., Magistrelli, P., van Duijn, C.M., Ricciardi, G., and Boccia, S. (2009). A case-control study on the effect of p53 and p73 gene polymorphisms on gastric cancer risk and progression. Mutat Res 675, 60-65.
41. De Villiers, E.-M. (2003). Relationship between steroid hormone contraceptives and HPV, cervical intraepithelial neoplasia, and cervical carcinoma. Int J Cancer 103, 705-708. (Pubitemid 36110224)
42. Duarte, I., Santos, A., Sousa, H., Catarino, R., Pinto, D., Matos, A., Pereira, D., Moutinho, J., Canedo, P., Machado, J.C., and Medeiros, R. (2005). G-308A TNF-a polymorphism is associated with an increased risk of invasive cervical cancer. Biochem Biophys Res Commun 334, 588-592. (Pubitemid 40982407)
43. Ferreira, P.M., Catarino, R., Pereira, D., Matos, A., Pinto, D., Coelho, A., Lopes, C., and Medeiros, R. (2006). Cervical cancer and CYP2E1 polymorphisms: implications for molecular epidemiology. Eur J Clin Pharmacol 62, 15-21. (Pubitemid 43106311)
44. Fiedler, M., Müller-Holzner, E., Viertler, H.P., Widschwendter, A., Laich, A., Pfister, G., Spoden, G.A., Jansen-Dürr, P., and Zwerschke, W. (2004). High level HPV-16E7 oncoprotein expression correlates with reduced pRb-levels in cervical biopsies. FASEB J 18, 1120-1122. (Pubitemid 39561543)
45. Han, S., Semba, S., Abe, T., Makino, N., Furukawa, T., Fukushige, S., Takahashi, H., Sakurada, A., Sato, M., Shiiba, K., Matsuno, S., Nimura, Y., Nakagawara, A., and Horii, A. (1999). Infrequent somatic mutations of the p73 gene in various human cancers. Eur J Surg Oncol 25, 194-198. (Pubitemid 29182464)
46. Hu, Z., Miao, X., Ma, H., Tan, W., Wang, X., Lu, D., Wei, Q., Lin, D., and Shen, H. (2005). Dinucleotide polymorphism of p73 gene is associated with a reduced risk of lung cancer in a Chinese population. Int J Cancer 114, 455-460. (Pubitemid 40279969)
47. Jeon, S., Allen-Hoffmann, B.L., and Lambert, P.F. (1995). Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells. J Virol 69, 2989-2997.
48. Ji, X., Sturgis, E.M., Zhao, C., Etzel, C.J., Wei, Q., and Li, G. (2009). Association of G4C14-to-A4T14 polymorphism with human papillomavirus type 16 status in squamous cell carcinoma of the head and neck in non-hispanic whites. Cancer 115, 1660-1668.
49. Jin, L., Qi, M., Chen, D.Z., Anderson, A., Yang, G.Y., Arbeit, J.M., and Auborn, K.J. (1999). Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice. Cancer Res 59, 3991-3997. (Pubitemid 29393567)
50. Koushik, A., Ghosh, A., Duarte-Franco, E., Forest, P., Voyer, H., Matlashewski, G., Coutlée, F., and Franco, E.L. (2005). Biomarkers of Cervical Cancer Risk (BCCR) Study Team. The p53 codon 72 polymorphism and risk of high-grade cervical intraepithelial neoplasia. Cancer Detect Prev 29, 307-316. (Pubitemid 41267288)
51. Lee, K.E., Hong, Y.S., Kim, B.G., Kim, N.Y., Lee, K.M., Kwak, J.Y., and Roh, M.S. (2010). p73 G4C14 to A4T14 polymorphism is associated with colorectal cancer risk and survival. World J Gastroenterol 16, 4448-4454.
52. Li, G., Sturgis, E.M., Wang, L.-E., Chamberlain, R.M., Amos, C.I., Spitz, M.R., El-Naggar, A.K., Hong, W.K., and Wei, Q. (2004a). Association of a p73 exon 2 G4C14-to -A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck. Carcinogenesis 25, 1911-1916. (Pubitemid 39405910)
53. Li, G., Wang, L.E., Chamberlain, R.M., Amos, C.I., Spitz, M.R., and Wei, Q. (2004b). p73 G4C14-to -A4T14 polymorphism and risk of lung cancer. Cancer Res 64, 6863-6866. (Pubitemid 39330992)
54. Liu, S.S., Leung, R.C., Chan, K.Y., Chiu, P.M., Cheung, A.N., Tam, K.F., Ng, T.Y., Wong, L.C., and Ngan, H.Y. (2004). p73 expression is associated with the cellular radiosensitivity in cervical cancer after radiotherapy. Clin Cancer Res 10, 3309-3316. (Pubitemid 38685435)
55. Mai, M., Yokomizo, A., Qian, C., Yang, P., Tindall, D.J., Smith, D.I., and Liu, W. (1998). Activation of p73 silent allele in lung cancer. Cancer Res 58, 2347-2349. (Pubitemid 28252692)
56. Marin, M.C., Jost, C.A., Irwin, M.S., DeCaprio, J.A., Caput, D., and Kaelin, W.G., Jr. (1998). Viral oncoproteins discriminate 228 CRAVEIRO ET AL. between p53 and the p53 homolog p73. Mol Cell Biol 18, 6316-6324. (Pubitemid 28500522)
57. Matos, A., Moutinho, J., Pinto, D., and Medeiros, R. (2005). The influence of smoking and other cofactors on the time to onset to cervical cancer in a southern European population. Eur J Cancer Prev 14, 485-491. (Pubitemid 41433648)
58. Medeiros, R., Prazeres, H., Pinto, D., Macedo-Pinto, I., Lacerda, M., Lopes, C., and Cruz, E. (2005). Characterization of HPV genotype profile in squamous cervical lesions in Portugal, a southern European population at high risk of cervical cancer. Eur J Cancer Prev 14, 467-471. (Pubitemid 41433645)
59. Merlo, P., Fulco, M., Constanzo, A., Mangiacasale, R., Strano, S., Blandino, G., Taya, Y., Lavia, P., and Levrero, M. (2005). A role of p73 in mitotic exit. J Biol Chem 280, 30354-30360. (Pubitemid 41216217)
60. Miller, K. (2003). Estrogen and DNA damage: the silent source of breast cancer? J Nat Cancer Inst 95, 100-102. (Pubitemid 36193257)
61. Mittal, R.D., George, G.P., Mishra, J., Mittal, T., and Kapoor, R. (2011). Role of functional polymorphisms of p53 and p73 genes with the risk of prostate cancer in a case-control study from Northern India. Arch Med Res 42, 122-127.
62. Nenutil, R., Ceskova, P., Coates, P.J., Nylander, K., and Vojtesek, B. (2003). Differential expression of p73alpha in normal ectocervical epithelium, cervical intraepithelial neoplasia, and invasive squamous cell carcinoma. Int J Gynecol Pathol 22, 386-392. (Pubitemid 37152990)
63. Newfield, L., Bradlow, H.L., Sepkovic, D.W., and Auborn, K. (1998). Estrogen metabolism and the malignant potential of human papillomavirus immortalized keratinocytes. Proc Soc Exp Biol Med 217, 322-326.
64. Niwa, Y., Hamajima, N., Atsuta, Y., Yamamoto, K., Tamakoshi, A., Saito, T., Hirose, K., Nakanishi, T., Nawa, A., Kuzuya, K., and Tajima, K. (2004). Genetic polymorphisms of p73 G4C14-to A4T14 at exon 2 and p53 Arg72Pro and the risk of cervical cancer in Japanese. Cancer Lett 205, 55-60. (Pubitemid 38230139)
65. Niwa, Y., Hirose, K., Matsuo, K., Tajima K., Ikoma, Y., Nakanishi, T, Nawa, A., Kuzuya, K., Tamakoshi, A., and Hamajima, N. (2005). Association of p73 G4C14-to -A4T14 polymorphism at exon 2 and p53 Arg72Pro polymorphism with the risk of endometrial cancer in Japanese subjects. Cancer Lett 219, 183-190. (Pubitemid 40269482)
66. Padma, A.S., Renil, M., and Thampan, R.V. (2000). Proteinprotein interactions that precede the nuclear entry of goat uterine estrogen receptor under cell-free conditions. J Cell Biochem 78, 650-665. (Pubitemid 30620710)
67. Park, J.S., Kim, E.J., Lee, J.Y., Sin, H.S., Namkoong, S.E., and Um, S.J. (2001). Functional inactivation of p73, a homolog of p53 tumor suppressor protein, by human papillomavirus E6 proteins. Int J Cancer 91, 822-827.
68. Pfeifer, D., Arbman, G., and Sun, X.F. (2005). Polymorphism of the p73 gene in relation to colorectal cancer risk and survival. Carcinogenesis 26, 103-107. (Pubitemid 40207704)
69. Prabhu, N.S., Somasundaram, K., Satyamoorthy, K., Herlyn, M., and El-Deiry, W.S. (1998). p73beta, unlike p53, suppresses growth and induces apoptosis of human papillomavirus E6-expressing cancer cells. Int J Oncol 13, 5-9.
70. Riley, R.R., Duensing, S., Brake, T., Münger, K., Lambert, P.F., and Arbeit, J.M. (2003). Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis. Cancer Res 63, 4862-4871. (Pubitemid 37022618)
71. Ryan, B.M., McManus, R., Daly, J.S., Carton, E., Keeling, P.W., Reynolds, J.V., and Kelleher, D. (2001). A common p73 polymorphism is associated with a reduced incidence of oesophageal carcinoma. Br J Cancer 85, 1499-1503. (Pubitemid 34001580)
72. Santos, A.M., Sousa, H., Catarino, R., Pinto, D., Pereira, D., Vasconcelos, A., Matos, A., Lopes, C., and Medeiros, R. (2005). TP53 codon 72 polymorphism and risk for cervical cancer in Portugal. Cancer Genet Cytogenet 159, 143-147. (Pubitemid 40719383)
73. Santos, A.M., Sousa, H., Pinto, D., Portela, C., Pereira, D., Catarino, R., Duarte, I., Lopes, C., Medeiros, R. (2006). Linking TP53 codon 72 and P21 nt590 genotypes to the development of cervical and ovarian cancer. Eur J Cancer 42, 958-963.
74. Schiffman, M.H., and Brinton, L.A. (1995). The epidemiology of cervical carcinogenesis. Cancer (Suppl) 76, 1888-1901.
75. Shew, M.L., McGlennen, R., Zaidi, N., Westerheim, M., Ireland, M., and Anderson, S. (2002). Oestrogen receptor transcripts associated with cervical human papillomavirus infection. Sex Transm Infect 78, 210-214. (Pubitemid 34666543)
76. Sousa, H., Santos, A.M., Catarino, R., Pinto, D., Vasconcelos, A., Lopes, C., Breda, E., Medeiros, R. (2006). Linkage of TP53 codon 72 pro/pro genotype as predictive factor for nasopharyngeal carcinoma development. Eur J Cancer Prev 15, 362-366. (Pubitemid 44060492)
77. Thomas, D.B., Qin, Q., Kuypers, J., Kiviat, N., Ashley, R.L., Koetsawang, A., Ray, R.M., and Koetsawang, S. (2001). Human papillomaviruses and cervical cancer in Bangkok. II. Risk factors for in situ and invasive squamous cell cervical carcinomas. Am J Epidemiol 153, 732-739. (Pubitemid 32319699)
78. Tommasino, M., Accardi, R., Caldeira, S., Dong, W., Malanchi, I., Smet, A., and Zehbe, I. (2003). The role of TP53 in cervical carcinogenesis. Hum Mutat 21, 307-312. (Pubitemid 36292973)
79. Walboomers, J.M., Jacobs, M.V., Manos, M.M., Bosch, F.X., Kummer, J.A., Shah, K.V., Snijders, P.J., Peto, J., Meijer, C.J., and Muñoz, N. (1999). Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol 189, 12-19. (Pubitemid 29406813)
80. zur Hausen, H. (2000). Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis. J Natl Cancer Inst 92, 690-698. (Pubitemid 30365529)