메뉴 건너뛰기




Volumn 32, Issue 3, 2012, Pages 467-475

Rifaximin improves thrombocytopenia in patients with alcoholic cirrhosis in association with reduction of endotoxaemia

Author keywords

Cirrhosis; Cytokines; Endotoxin; Thrombocytopenia

Indexed keywords

CYTOKINE; ENDOTOXIN; INTERLEUKIN 1; INTERLEUKIN 6; RIFAXIMIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84856683368     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2011.02650.x     Document Type: Article
Times cited : (45)

References (46)
  • 1
    • 42949134758 scopus 로고    scopus 로고
    • Review article: blood platelet number and function in chronic liver disease and cirrhosis
    • Witters P, Freson K, Verslype C, et al. Review article: blood platelet number and function in chronic liver disease and cirrhosis. Aliment Pharmacol Ther 2008; 27: 1017-29.
    • (2008) Aliment Pharmacol Ther , vol.27 , pp. 1017-1029
    • Witters, P.1    Freson, K.2    Verslype, C.3
  • 2
    • 43049158112 scopus 로고    scopus 로고
    • Thrombocytopenia associated with chronic liver disease
    • Afdhal N, McHutchinson J, Brown R, et al. Thrombocytopenia associated with chronic liver disease. J Hepatol 2008; 48: 1000-7.
    • (2008) J Hepatol , vol.48 , pp. 1000-1007
    • Afdhal, N.1    McHutchinson, J.2    Brown, R.3
  • 3
    • 69949109982 scopus 로고    scopus 로고
    • Abnormal hematological indices in cirrhosis
    • Qamar AA, Grace ND. Abnormal hematological indices in cirrhosis. Can J Gastroenterol 2009; 23: 441-5.
    • (2009) Can J Gastroenterol , vol.23 , pp. 441-445
    • Qamar, A.A.1    Grace, N.D.2
  • 4
    • 66149190551 scopus 로고    scopus 로고
    • Incidence, prevalence, and clinical significance of abnormal hematologic indices in compensated cirrhosis
    • Qamar AA, Grace ND, Groszmann RJ, et al. Incidence, prevalence, and clinical significance of abnormal hematologic indices in compensated cirrhosis. Clin Gastroenterol Hepatol 2009; 7: 689-95.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 689-695
    • Qamar, A.A.1    Grace, N.D.2    Groszmann, R.J.3
  • 5
    • 0141457204 scopus 로고    scopus 로고
    • Predictors and implications of severe hypersplenism in patients with cirrhosis
    • Liangpunsakul S, Ulmer BJ, Chalasani N. Predictors and implications of severe hypersplenism in patients with cirrhosis. Am J Med Sci 2003; 326: 111-6.
    • (2003) Am J Med Sci , vol.326 , pp. 111-116
    • Liangpunsakul, S.1    Ulmer, B.J.2    Chalasani, N.3
  • 6
    • 0033198952 scopus 로고    scopus 로고
    • Apredictive model for failure to control bleeding during acute variceal haemorrhage
    • Ben-Ari Z, Cardin F, McCormick AP, Wannamethee G, Burroughs AK. Apredictive model for failure to control bleeding during acute variceal haemorrhage. J Hepatol 1999; 31: 443-50.
    • (1999) J Hepatol , vol.31 , pp. 443-450
    • Ben-Ari, Z.1    Cardin, F.2    McCormick, A.P.3    Wannamethee, G.4    Burroughs, A.K.5
  • 7
    • 0029854496 scopus 로고    scopus 로고
    • Measurement of spleen size and its relation to hypersplenism and portal hemodynamics in portal hypertension due to hepatic cirrhosis
    • Shah SH, Haves PC, Allan PL, Nicoll J, Finlayson ND. Measurement of spleen size and its relation to hypersplenism and portal hemodynamics in portal hypertension due to hepatic cirrhosis. Am J Gastroenterol 1996; 91: 2580-3.
    • (1996) Am J Gastroenterol , vol.91 , pp. 2580-2583
    • Shah, S.H.1    Haves, P.C.2    Allan, P.L.3    Nicoll, J.4    Finlayson, N.D.5
  • 10
    • 12344253716 scopus 로고    scopus 로고
    • Thrombopoietin (TPO) levels in hepatic patients with thrombocytopenia
    • Aref S, Mabed M, Selim T, Goda T, Khafagy N. Thrombopoietin (TPO) levels in hepatic patients with thrombocytopenia. Hematology 2004; 9: 351-6.
    • (2004) Hematology , vol.9 , pp. 351-356
    • Aref, S.1    Mabed, M.2    Selim, T.3    Goda, T.4    Khafagy, N.5
  • 11
    • 78649854651 scopus 로고    scopus 로고
    • Thrombocytopenia associated with chronic liver disease: effects of rifaximin on platelet count
    • Kalambokis G, Tsianos EV. Thrombocytopenia associated with chronic liver disease: effects of rifaximin on platelet count. Am J Gastroenterol 2010; 105: 2705-7.
    • (2010) Am J Gastroenterol , vol.105 , pp. 2705-2707
    • Kalambokis, G.1    Tsianos, E.V.2
  • 12
    • 0028899265 scopus 로고
    • Rifaximin. A review of this antibacterial activity, pharmacokinetic properties and therapeutic potential in conditions mediated by gastrointestinal bacteria
    • Gillis JC, Brogden RN. Rifaximin. A review of this antibacterial activity, pharmacokinetic properties and therapeutic potential in conditions mediated by gastrointestinal bacteria. Drugs 1995; 49: 467-84.
    • (1995) Drugs , vol.49 , pp. 467-484
    • Gillis, J.C.1    Brogden, R.N.2
  • 13
    • 74249111354 scopus 로고    scopus 로고
    • Rifaximin: a unique gastrointestinal-selective antibiotic for enteric diseases
    • Koo HL, DuPont HL. Rifaximin: a unique gastrointestinal-selective antibiotic for enteric diseases. Curr Opin Gastroenterol 2010; 26: 17-25.
    • (2010) Curr Opin Gastroenterol , vol.26 , pp. 17-25
    • Koo, H.L.1    DuPont, H.L.2
  • 14
    • 63849083717 scopus 로고    scopus 로고
    • Intestinal decontamination improves liver haemodynamics in patients with alcohol-related decompensated cirrhosis
    • Vlachogiannakos J, Saveriadis AS, Viazis N, et al. Intestinal decontamination improves liver haemodynamics in patients with alcohol-related decompensated cirrhosis. Aliment Pharmacol Ther 2009; 29: 992-9.
    • (2009) Aliment Pharmacol Ther , vol.29 , pp. 992-999
    • Vlachogiannakos, J.1    Saveriadis, A.S.2    Viazis, N.3
  • 15
    • 0023901892 scopus 로고
    • Endotoxin levels measured by a chromogenic assay in portal, hepatic and peripheral blood in patients with cirrhosis
    • Lumsden AB, Henderson JM, Kutner MH. Endotoxin levels measured by a chromogenic assay in portal, hepatic and peripheral blood in patients with cirrhosis. Hepatology 1988; 8: 232-6.
    • (1988) Hepatology , vol.8 , pp. 232-236
    • Lumsden, A.B.1    Henderson, J.M.2    Kutner, M.H.3
  • 16
    • 0026691627 scopus 로고
    • Serum levels of cytokines in chronic liver diseases
    • Tilg H, Wilmer A, Vogel W, et al. Serum levels of cytokines in chronic liver diseases. Gastroenterology 1992; 103: 264-74.
    • (1992) Gastroenterology , vol.103 , pp. 264-274
    • Tilg, H.1    Wilmer, A.2    Vogel, W.3
  • 17
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 1993; 329: 2002-12.
    • (1993) N Engl J Med , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 18
    • 1842453220 scopus 로고    scopus 로고
    • Gut microflora in the pathogenesis of the complications of cirrhosis
    • Garcia-Tsao G. Gut microflora in the pathogenesis of the complications of cirrhosis. Best Pract Res Clin Gastroenterol 2004; 18: 353-72.
    • (2004) Best Pract Res Clin Gastroenterol , vol.18 , pp. 353-372
    • Garcia-Tsao, G.1
  • 19
    • 78650175565 scopus 로고    scopus 로고
    • Endotoxaemia in the pathogenesis of cytopenias in liver cirrhosis. Could simple antibiotics raise blood counts?
    • Kalambokis G, Tsianos EV. Endotoxaemia in the pathogenesis of cytopenias in liver cirrhosis. Could simple antibiotics raise blood counts? Med Hypotheses 2011; 76: 105-9.
    • (2011) Med Hypotheses , vol.76 , pp. 105-109
    • Kalambokis, G.1    Tsianos, E.V.2
  • 20
    • 0032478409 scopus 로고    scopus 로고
    • Recommendations to prevent and control iron deficiency in the United States: Centers for Disease Control and Prevention
    • Recommendations to prevent and control iron deficiency in the United States: Centers for Disease Control and Prevention. MMWR Recomm Rep 1998; 3: 1-29.
    • (1998) MMWR Recomm Rep , vol.3 , pp. 1-29
  • 21
    • 0015028560 scopus 로고
    • Dimensions of the normal adult spleen scan and prediction of spleen weight
    • Larson SM, Tuell SH, Moores KD, Nelp WB. Dimensions of the normal adult spleen scan and prediction of spleen weight. J Nucl Med 1971; 12: 123-6.
    • (1971) J Nucl Med , vol.12 , pp. 123-126
    • Larson, S.M.1    Tuell, S.H.2    Moores, K.D.3    Nelp, W.B.4
  • 22
    • 0025806025 scopus 로고
    • Inter-relationships between platelet counts, platelet IgG, serum IgG, immune complexes, and severity of liver disease
    • De Noronha R, Taylor BA, Wild G, Triger DR, Greaves M. Inter-relationships between platelet counts, platelet IgG, serum IgG, immune complexes, and severity of liver disease. Clin Lab Haematol 1991; 13: 127-35.
    • (1991) Clin Lab Haematol , vol.13 , pp. 127-135
    • De Noronha, R.1    Taylor, B.A.2    Wild, G.3    Triger, D.R.4    Greaves, M.5
  • 24
    • 30444436765 scopus 로고    scopus 로고
    • Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo
    • Aslam R, Speck ER, Kim M, et al. Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo. Blood 2006; 107: 637-41.
    • (2006) Blood , vol.107 , pp. 637-641
    • Aslam, R.1    Speck, E.R.2    Kim, M.3
  • 25
    • 0018772982 scopus 로고
    • Correlation between serum IgG, platelet membrane IgG, and platelet function in hypergammaglobulinemic states
    • McGrath KM, Stuart JJ, Richards F II. Correlation between serum IgG, platelet membrane IgG, and platelet function in hypergammaglobulinemic states. Br J Haematol 1979; 42: 585-91.
    • (1979) Br J Haematol , vol.42 , pp. 585-591
    • McGrath, K.M.1    Stuart, J.J.2    Richards II, F.3
  • 26
    • 0038241772 scopus 로고    scopus 로고
    • A role of autoantibody-mediated platelet destruction in thrombocytopenia in patients with cirrhosis
    • Kajihara M, Kato S, Okazaki Y, et al. A role of autoantibody-mediated platelet destruction in thrombocytopenia in patients with cirrhosis. Hepatology 2003; 37: 1267-76.
    • (2003) Hepatology , vol.37 , pp. 1267-1276
    • Kajihara, M.1    Kato, S.2    Okazaki, Y.3
  • 27
    • 0009673797 scopus 로고    scopus 로고
    • Platelet accumulation induced by bacterial endotoxin in rats
    • Itoh H, Cicala C, Douglas GJ, Page CP. Platelet accumulation induced by bacterial endotoxin in rats. Thromb Res 1996; 83: 405-19.
    • (1996) Thromb Res , vol.83 , pp. 405-419
    • Itoh, H.1    Cicala, C.2    Douglas, G.J.3    Page, C.P.4
  • 28
    • 0029155948 scopus 로고
    • Association between low-grade disseminated intravascular coagulation and endotoxemia in patients with liver cirrhosis
    • Violi F, Ferri D, Basili S, et al. Association between low-grade disseminated intravascular coagulation and endotoxemia in patients with liver cirrhosis. Gastroenterology 1995; 109: 531-9.
    • (1995) Gastroenterology , vol.109 , pp. 531-539
    • Violi, F.1    Ferri, D.2    Basili, S.3
  • 29
    • 0027957298 scopus 로고
    • Effect of human recombinant cytokines on the induction of macrophages procoagulant activity
    • Schwager I, Jungi TW. Effect of human recombinant cytokines on the induction of macrophages procoagulant activity. Blood 1994; 83: 152-60.
    • (1994) Blood , vol.83 , pp. 152-160
    • Schwager, I.1    Jungi, T.W.2
  • 30
    • 0040550693 scopus 로고    scopus 로고
    • HLA-DR-mediated signals for hematopoiesis and induction of apoptosis involve but are not limited to a nitric oxide pathway
    • Lee JW, Beckham C, Michel BR, Rosen H, Deeg HJ. HLA-DR-mediated signals for hematopoiesis and induction of apoptosis involve but are not limited to a nitric oxide pathway. Blood 1997; 90: 217-25.
    • (1997) Blood , vol.90 , pp. 217-225
    • Lee, J.W.1    Beckham, C.2    Michel, B.R.3    Rosen, H.4    Deeg, H.J.5
  • 31
    • 17344363971 scopus 로고    scopus 로고
    • Blunted thrompbopoietin response to interferon alfa-induced thrombocytopenia of patients with liver cirrhosis
    • Peck-Radosavljevic M, Wichlas M, Pidlich J, et al. Blunted thrompbopoietin response to interferon alfa-induced thrombocytopenia of patients with liver cirrhosis. Hepatology 1998; 28: 1424-9.
    • (1998) Hepatology , vol.28 , pp. 1424-1429
    • Peck-Radosavljevic, M.1    Wichlas, M.2    Pidlich, J.3
  • 32
    • 7944233056 scopus 로고    scopus 로고
    • Expression of TNF-related apoptosis-inducing ligand (TRAIL) in megacaryocytes and platelets
    • Crist SA, Elzey BD, Ludwig AT, et al. Expression of TNF-related apoptosis-inducing ligand (TRAIL) in megacaryocytes and platelets. Exp Hematol 2004; 32: 1073-81.
    • (2004) Exp Hematol , vol.32 , pp. 1073-1081
    • Crist, S.A.1    Elzey, B.D.2    Ludwig, A.T.3
  • 33
    • 0035525771 scopus 로고    scopus 로고
    • Interleukin-6 stimulates thrombopoiesis through thrombopoietin: the role in inflammatory thrombocytosis
    • Kaser A, Brandacher G, Steurer W, et al. Interleukin-6 stimulates thrombopoiesis through thrombopoietin: the role in inflammatory thrombocytosis. Blood 2001; 98: 2720-5.
    • (2001) Blood , vol.98 , pp. 2720-2725
    • Kaser, A.1    Brandacher, G.2    Steurer, W.3
  • 34
    • 0032910590 scopus 로고    scopus 로고
    • Thrombopoietic cytokines and reversal of thrombocytopenia after liver transplantation
    • Peck-Radosavljevic M, Zacheri J, Wichlas M, et al. Thrombopoietic cytokines and reversal of thrombocytopenia after liver transplantation. Eur J Gastroenterol Hepatol 1999; 11: 151-6.
    • (1999) Eur J Gastroenterol Hepatol , vol.11 , pp. 151-156
    • Peck-Radosavljevic, M.1    Zacheri, J.2    Wichlas, M.3
  • 35
    • 49749092336 scopus 로고    scopus 로고
    • Anemia of chronic disease: a harmful disorder or an adaptive, beneficial response?
    • Zarychanski R, Houston DS. Anemia of chronic disease: a harmful disorder or an adaptive, beneficial response? CMAJ 2008; 179: 333-7.
    • (2008) CMAJ , vol.179 , pp. 333-337
    • Zarychanski, R.1    Houston, D.S.2
  • 36
    • 0035284823 scopus 로고    scopus 로고
    • Promotion of neutrophil apoptosis by TNF-α
    • Salamone G, Giordano M, Trevani AS, et al. Promotion of neutrophil apoptosis by TNF-α. J Immunol 2001; 166: 3476-83.
    • (2001) J Immunol , vol.166 , pp. 3476-3483
    • Salamone, G.1    Giordano, M.2    Trevani, A.S.3
  • 37
    • 0033930702 scopus 로고    scopus 로고
    • Dialysate related cytokine induction and response to recombinant human erythropoietin in haemodynamic patients
    • Sitter T, Bergner A, Schiffl H. Dialysate related cytokine induction and response to recombinant human erythropoietin in haemodynamic patients. Nephrol Dial Transplant 2000; 15: 1207-11.
    • (2000) Nephrol Dial Transplant , vol.15 , pp. 1207-1211
    • Sitter, T.1    Bergner, A.2    Schiffl, H.3
  • 38
    • 0036413580 scopus 로고    scopus 로고
    • Erythropoietin resistance: the role of inflammation and pro-inflammatory cytokines
    • Macdougall IC, Cooper AC. Erythropoietin resistance: the role of inflammation and pro-inflammatory cytokines. Nephrol Dial Transplant 2002; 17: 39-43.
    • (2002) Nephrol Dial Transplant , vol.17 , pp. 39-43
    • Macdougall, I.C.1    Cooper, A.C.2
  • 39
    • 0030881463 scopus 로고    scopus 로고
    • Anaemia of chronic disease in rheumatoid arthritis: in vivo effects of tumor necrosis factor α blockade
    • Davis D, Charles PJ, Potter A, et al. Anaemia of chronic disease in rheumatoid arthritis: in vivo effects of tumor necrosis factor α blockade. Br J Rheumatol 1997; 36: 950-6.
    • (1997) Br J Rheumatol , vol.36 , pp. 950-956
    • Davis, D.1    Charles, P.J.2    Potter, A.3
  • 40
    • 0035133561 scopus 로고    scopus 로고
    • Bacterial translocation of enteric organisms in patients with cirrhosis
    • Cirera I, Bauer TM, Navasa M, et al. Bacterial translocation of enteric organisms in patients with cirrhosis. J Hepatol 2001; 34: 32-7.
    • (2001) J Hepatol , vol.34 , pp. 32-37
    • Cirera, I.1    Bauer, T.M.2    Navasa, M.3
  • 41
    • 0037219393 scopus 로고    scopus 로고
    • Increased lipopolysaccharide binding protein in cirrhotic patients with marked immune and hemodynamic derangement
    • Albillos A, de la Hera A, Gonzalez M, et al. Increased lipopolysaccharide binding protein in cirrhotic patients with marked immune and hemodynamic derangement. Hepatology 2003; 37: 208-17.
    • (2003) Hepatology , vol.37 , pp. 208-217
    • Albillos, A.1    de la Hera, A.2    Gonzalez, M.3
  • 42
    • 1642535481 scopus 로고    scopus 로고
    • The effect of selective intestinal decontamination on the hyperdynamic circulatory state in cirrhosis
    • Rasaratnam B, Kaye D, Jennings G, Dudley F, Chin-Dusting J. The effect of selective intestinal decontamination on the hyperdynamic circulatory state in cirrhosis. Ann Intern Med 2003; 139: 186-93.
    • (2003) Ann Intern Med , vol.139 , pp. 186-193
    • Rasaratnam, B.1    Kaye, D.2    Jennings, G.3    Dudley, F.4    Chin-Dusting, J.5
  • 43
    • 0029069926 scopus 로고
    • Effective of selective bowel decontamination with norfloxacin on spontaneous bacterial peritonitis, translocation and survival in an animal model of cirrhosis
    • Runyon B, Borzio M, Young S, et al. Effective of selective bowel decontamination with norfloxacin on spontaneous bacterial peritonitis, translocation and survival in an animal model of cirrhosis. Hepatology 1995; 21: 1719-24.
    • (1995) Hepatology , vol.21 , pp. 1719-1724
    • Runyon, B.1    Borzio, M.2    Young, S.3
  • 44
    • 79952188432 scopus 로고    scopus 로고
    • Thrombopoietic growth factors in the treatment of immune thrombocytopenic purpura
    • Wang T, Wang Z, Yang R. Thrombopoietic growth factors in the treatment of immune thrombocytopenic purpura. Crit Rev Oncol Hematol 2011; 77: 172-83.
    • (2011) Crit Rev Oncol Hematol , vol.77 , pp. 172-183
    • Wang, T.1    Wang, Z.2    Yang, R.3
  • 45
    • 4344564900 scopus 로고    scopus 로고
    • Erythropoietin increases platelet reactivity and platelet counts in patients with alcoholic liver cirrhosis: a randomized, double-blind, placebo-controlled study
    • Homoncik M, Jilma-Stohlawetz P, Schmid M, Ferlitsch A, Peck-Radosavljevic M. Erythropoietin increases platelet reactivity and platelet counts in patients with alcoholic liver cirrhosis: a randomized, double-blind, placebo-controlled study. Aliment Pharmacol Ther 2004; 20: 437-43.
    • (2004) Aliment Pharmacol Ther , vol.20 , pp. 437-443
    • Homoncik, M.1    Jilma-Stohlawetz, P.2    Schmid, M.3    Ferlitsch, A.4    Peck-Radosavljevic, M.5
  • 46
    • 0027969051 scopus 로고
    • Thrombocytopenia of chronic liver disease corrected by erythropoietin treatment
    • Pirisi M, Fabris C, Soardo G, et al. Thrombocytopenia of chronic liver disease corrected by erythropoietin treatment. J Hepatol 1994; 21: 376-80.
    • (1994) J Hepatol , vol.21 , pp. 376-380
    • Pirisi, M.1    Fabris, C.2    Soardo, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.