-
1
-
-
63149192143
-
Global and local epidemiology of community-acquired pneumonia: The experience of the CAPNETZ network
-
Welte T, Kohnlein T: Global and local epidemiology of community-acquired pneumonia: the experience of the CAPNETZ Network. Semin Respir Crit Care Med. 2009;30:127-135.
-
(2009)
Semin Respir Crit Care Med.
, vol.30
, pp. 127-135
-
-
Welte, T.1
Kohnlein, T.2
-
2
-
-
33746930791
-
Lung epithelium as a sentinel and effector system in pneumonia-Molecular mechanisms of pathogen recognition and signal transduction
-
Hippenstiel S, Opitz B, Schmeck B, Suttorp N: Lung epithelium as a sentinel and effector system in pneumonia-molecular mechanisms of pathogen recognition and signal transduction. Respir Res. 2006;7:97.
-
(2006)
Respir Res
, vol.7
, pp. 97
-
-
Hippenstiel, S.1
Opitz, B.2
Schmeck, B.3
Suttorp, N.4
-
4
-
-
0033168728
-
Cutting edge: Recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2
-
Yoshimura A, Lien E, Ingalls RR, Tuomanen E, Dziarski R, Golenbock D: Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. J Immunol. 1999;163: 1-5. (Pubitemid 29295815)
-
(1999)
Journal of Immunology
, vol.163
, Issue.1
, pp. 1-5
-
-
Yoshimura, A.1
Lien, E.2
Ingalls, R.R.3
Tuomanen, E.4
Dziarski, R.5
Golenbock, D.6
-
5
-
-
0037452778
-
Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection
-
DOI 10.1073/pnas.0435928100
-
Malley R, Henneke P, Morse SC, Cieslewicz MJ, Lipsitch M, Thompson CM, Kurt-Jones E, Paton JC, Wessels MR, Golenbock DT: Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection. Proc Natl Acad Sci USA. 2003;100:1966-1971. (Pubitemid 36254557)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.4
, pp. 1966-1971
-
-
Malley, R.1
Henneke, P.2
Morse, S.C.3
Cieslewicz, M.J.4
Lipsitch, M.5
Thompson, C.M.6
Kurt-Jones, E.7
Paton, J.C.8
Wessels, M.R.9
Golenbock, D.T.10
-
6
-
-
33746858897
-
Streptococcus pneumoniae induced c-Jun-N-terminal kinase-and AP-1-dependent IL-8 release by lung epithelial BEAS-2B cells
-
Schmeck B, Moog K, Zahlten J, van L, V, N'Guessan PD, Opitz B, Rosseau S, Suttorp N, Hippenstiel S: Streptococcus pneumoniae induced c-Jun-N-terminal kinase-and AP-1-dependent IL-8 release by lung epithelial BEAS-2B cells. Respir Res. 2006;7:98.
-
(2006)
Respir Res.
, vol.7
, pp. 98
-
-
Schmeck, B.1
Moog, K.2
Zahlten, J.3
Van L, V.4
N'Guessan, P.D.5
Opitz, B.6
Rosseau, S.7
Suttorp, N.8
Hippenstiel, S.9
-
7
-
-
0032032651
-
Lipopolysaccharide and pneumococcal cell wall components activate the mitogen activated protein kinases (MAPK) erk-1, erk-2, and p38 in astrocytes
-
DOI 10.1002/(SICI)1098-1136(199803)22:3< 295::AID-GLIA8>3.0.CO;2-4
-
Schumann RR, Pfeil D, Freyer D, Buerger W, Lamping N, Kirschning CJ, Goebel UB, Weber JR: Lipopolysaccharide and pneumococcal cell wall components activate the mitogen activated protein kinases (MAPK) erk-1, erk-2, and p38 in astro-cytes. Glia. 1998;22:295-305. (Pubitemid 28159020)
-
(1998)
GLIA
, vol.22
, Issue.3
, pp. 295-305
-
-
Schumann, R.R.1
Pfeil, D.2
Freyer, D.3
Buerger, W.4
Lamping, N.5
Kirschning, C.J.6
Goebel, U.B.7
Weber, J.R.8
-
9
-
-
37149044989
-
The role of epithelial β-defensins and cathelicidins in host defense of the lung
-
DOI 10.1080/01902140701756687, PII 788421908
-
Hiemstra PS: The role of epithelial beta-defensins and cathelicidins in host defense of the lung. Exp Lung Res. 2007;33:537-542. (Pubitemid 350256088)
-
(2007)
Experimental Lung Research
, vol.33
, Issue.10
, pp. 537-542
-
-
Hiemstra, P.S.1
-
10
-
-
0035430147
-
Human beta-defensin 4: A novel inducible pep-tide with a specifc salt-sensitive spectrum of antimicrobial activity
-
Garcia JR, Krause A, Schulz S, Rodriguez-Jimenez FJ, Kluver E, Adermann K, Forssmann U, Frimpong-Boateng A, Bals R, Forssmann WG: Human beta-defensin 4: a novel inducible pep-tide with a specifc salt-sensitive spectrum of antimicrobial activity. FASEB J. 2001;15:1819-1821.
-
(2001)
FASEB J
, vol.15
, pp. 1819-1821
-
-
Garcia, J.R.1
Krause, A.2
Schulz, S.3
Rodriguez-Jimenez, F.J.4
Kluver, E.5
Adermann, K.6
Forssmann, U.7
Frimpong-Boateng, A.8
Bals, R.9
Forssmann, W.G.10
-
11
-
-
0035937107
-
Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic
-
Harder J, Bartels J, Christophers E, Schroder JM: Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic. J Biol Chem. 2001;276:5707-5713.
-
(2001)
J Biol Chem.
, vol.276
, pp. 5707-5713
-
-
Harder, J.1
Bartels, J.2
Christophers, E.3
Schroder, J.M.4
-
13
-
-
65349178179
-
Human beta-defensin-3 promotes wound healing in infected diabetic wounds
-
Hirsch T, Spielmann M, Zuhaili B, Fossum M, Metzig M, Koehler T, Steinau HU, Yao F, Onderdonk AB, Steinstraesser L, Eriksson E: Human beta-defensin-3 promotes wound healing in infected diabetic wounds. J Gene Med. 2009;1:220-228.
-
(2009)
J Gene Med
, vol.1
, pp. 220-228
-
-
Hirsch, T.1
Spielmann, M.2
Zuhaili, B.3
Fossum, M.4
Metzig, M.5
Koehler, T.6
Steinau, H.U.7
Yao, F.8
Onderdonk, A.B.9
Steinstraesser, L.10
Eriksson, E.11
-
14
-
-
49049103117
-
Human beta defensin 2 promotes intestinal wound healing in vitro
-
Otte JM, Werner I, Brand S, Chromik AM, Schmitz F, Kleine M, Schmidt WE: Human beta defensin 2 promotes intestinal wound healing in vitro. J Cell Biochem. 2008;104: 2286-2297.
-
(2008)
J Cell Biochem
, vol.104
, pp. 2286-2297
-
-
Otte, J.M.1
Werner, I.2
Brand, S.3
Chromik, A.M.4
Schmitz, F.5
Kleine, M.6
Schmidt, W.E.7
-
15
-
-
27944437531
-
Expression of human β-defensin-3 in gingival epithelia
-
DOI 10.1111/j.1600-0765.2005.00827.x
-
Lu Q, Samaranayake LP, Darveau RP, Jin L: Expression of human beta-defensin-3 in gingival epithelia. J Periodontal Res. 2005;40:474-481. (Pubitemid 41673752)
-
(2005)
Journal of Periodontal Research
, vol.40
, Issue.6
, pp. 474-481
-
-
Lu, Q.1
Samaranayake, L.P.2
Darveau, R.P.3
Jin, L.4
-
16
-
-
52049084575
-
Regulation of human beta-defensin-2 by mycobacterium bovis bacillus calmette-guérin (BCG): Involvement of pkc, jnk, and pi3k in human lung epithelial cell line (A549)
-
Mendez-Samperio P, Miranda E, Trejo A: Regulation of human beta-defensin-2 by Mycobacterium bovis bacillus Calmette-Guérin (BCG): involvement of PKC, JNK, and PI3K in human lung epithelial cell line (A549). Peptides. 2008;29:1657-1663.
-
(2008)
Peptides
, vol.29
, pp. 1657-1663
-
-
Mendez-Samperio, P.1
Miranda, E.2
Trejo, A.3
-
17
-
-
33845476244
-
Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human β-defensin 3 in skin keratinocytes
-
DOI 10.1128/IAI.00389-06
-
Menzies BE, Kenoyer A: Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human beta-defensin 3 in skin keratinocytes. Infect Immun. 2006;74:6847-6854. (Pubitemid 44913160)
-
(2006)
Infection and Immunity
, vol.74
, Issue.12
, pp. 6847-6854
-
-
Menzies, B.E.1
Kenoyer, A.2
-
18
-
-
67650069160
-
The expression of the beta-defensins hbd-2 and hbd-3 is differentially regulated by nf-kappab and mapk/ap-1 pathways in an in vitro model of candida esophagitis
-
Steubesand N, Kiehne K, Brunke G, Pahl R, Reiss K, Herzig KH, Schubert S, Schreiber S, Folsch UR, Rosenstiel P, Arlt A: The expression of the beta-defensins hBD-2 and hBD-3 is differentially regulated by NF-kappaB and MAPK/AP-1 pathways in an in vitro model of Candida esophagitis. BMC Immunol. 2009;10:36.
-
(2009)
BMC Immunol
, vol.10
, pp. 36
-
-
Steubesand, N.1
Kiehne, K.2
Brunke, G.3
Pahl, R.4
Reiss, K.5
Herzig, K.H.6
Schubert, S.7
Schreiber, S.8
Folsch, U.R.9
Rosenstiel, P.10
Arlt, A.11
-
19
-
-
33644749261
-
Pseudomonas aeruginosa- and IL-1β-mediated induction of human β-defensin-2 in keratinocytes is controlled by NF-κB and AP-1
-
DOI 10.1038/sj.jid.5700020, PII 5700020
-
Wehkamp K, Schwichtenberg L, Schroder JM, Harder J: Pseu-domonas aeruginosa-and IL-1beta-mediated induction of human beta-defensin-2 in keratinocytes is controlled by NF-kappaB and AP-1. J Invest Dermatol. 2006;126:121-127. (Pubitemid 43336103)
-
(2006)
Journal of Investigative Dermatology
, vol.126
, Issue.1
, pp. 121-127
-
-
Wehkamp, K.1
Schwichtenberg, L.2
Schroder, J.-M.M.3
Harder, J.4
-
20
-
-
34548721076
-
Il-4 and il-13 negatively regulate tnf-alpha-and ifn-gamma-induced beta-defensin expression through stat-6, suppressor of cytokine signaling (SOCS)-1, and socs-3
-
Albanesi C, Fairchild HR, Madonna S, Scarponi C, De Pita O, Leung DY, Howell MD: IL-4 and IL-13 negatively regulate TNF-alpha-and IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of cytokine signaling (SOCS)-1, and SOCS-3. J Immunol. 2007;179:984-992.
-
(2007)
J Immunol
, vol.179
, pp. 984-992
-
-
Albanesi, C.1
Fairchild, H.R.2
Madonna, S.3
Scarponi, C.4
De Pita, O.5
Leung, D.Y.6
Howell, M.D.7
-
21
-
-
3042717148
-
Up-regulation of human beta-defensin 2 by interleukin-1beta in a549 cells: Involvement of pi3k, pkc, p38 mapk, jnk, and nf-kappab
-
Jang BC, Lim KJ, Paik JH, Kwon YK, Shin SW, Kim SC, Jung TY, Kwon TK, Cho JW, Baek WK, Kim SP, Suh MH, Suh SI: Up-regulation of human beta-defensin 2 by interleukin-1beta in A549 cells: involvement of PI3K, PKC, p38 MAPK, JNK, and NF-kappaB. Biochem Biophys Res Com-mun. 2004;320:1026-1033.
-
(2004)
Biochem Biophys Res Com-mun
, vol.320
, pp. 1026-1033
-
-
Jang, B.C.1
Lim, K.J.2
Paik, J.H.3
Kwon, Y.K.4
Shin, S.W.5
Kim, S.C.6
Jung, T.Y.7
Kwon, T.K.8
Cho, J.W.9
Baek, W.K.10
Kim, S.P.11
Suh, M.H.12
Suh, S.I.13
-
22
-
-
0038028733
-
Increased concentrations of human β-defensins in plasma and bronchoalveolar lavage fluid of patients with diffuse panbronchiolitis
-
DOI 10.1136/thorax.58.5.425
-
Hiratsuka T, Mukae H, Iiboshi H, Ashitani J, Nabeshima K, Minematsu T, Chino N, Ihi T, Kohno S, Nakazato M: Increased concentrations of human beta-defensins in plasma and bronchoalveolar lavage fuid of patients with diffuse panbron-chiolitis. Thorax. 2003;58:425-430. (Pubitemid 36560946)
-
(2003)
Thorax
, vol.58
, Issue.5
, pp. 425-430
-
-
Hiratsuka, T.1
Mukae, H.2
Iiboshi, H.3
Ashitani, J.4
Nabeshima, K.5
Minematsu, T.6
Chino, N.7
Ihi, T.8
Kohno, S.9
Nakazato, M.10
-
23
-
-
31844433263
-
Identification of hBD-3 in respiratory tract and serum: The increase in pneumonia
-
DOI 10.1183/09031936.06.00105904
-
Ishimoto H, Mukae H, Date Y, Shimbara T, Mondal MS, Ashitani J, Hiratsuka T, Kubo S, Kohno S, Nakazato M: Iden-tifcation of hBD-3 in respiratory tract and serum: the increase in pneumonia. Eur Respir J. 2006;27:253-260. (Pubitemid 43180899)
-
(2006)
European Respiratory Journal
, vol.27
, Issue.2
, pp. 253-260
-
-
Ishimoto, H.1
Mukae, H.2
Date, Y.3
Shimbara, T.4
Mondal, M.S.5
Ashitani, J.6
Hiratsuka, T.7
Kubo, S.8
Kohno, S.9
Nakazato, M.10
-
24
-
-
0023944920
-
Transformation of human bronchial epithelial cells by infection with sv40 or adenovirus-12 sv40 hybrid virus, or transfection via strontium phosphate coprecipitation with a plasmid containing sv40 early region genes
-
Reddel RR, Ke Y, Gerwin BI, McMenamin MG, Lechner JF, Su RT, Brash DE, Park JB, Rhim JS, Harris CC: Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate coprecipitation with a plasmid containing SV40 early region genes. Cancer Res. 1988;48:1904-1909.
-
(1988)
Cancer Res
, vol.48
, pp. 1904-1909
-
-
Reddel, R.R.1
Ke, Y.2
Gerwin, B.I.3
McMenamin, M.G.4
Lechner, J.F.5
Su, R.T.6
Brash, D.E.7
Park, J.B.8
Rhim, J.S.9
Harris, C.C.10
-
25
-
-
19944422390
-
Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor
-
DOI 10.1074/jbc.M313702200
-
Schmeck B, Zahlten J, Moog K, van L, V, Huber S, Hocke AC, Opitz B, Hoffmann E, Kracht M, Zerrahn J, Hammerschmidt S, Rosseau S, Suttorp N, Hippenstiel S: Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor. J Biol Chem. 2004;279:53241-53247. (Pubitemid 40051827)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.51
, pp. 53241-53247
-
-
Schmeck, B.1
Zahlten, J.2
Moog, K.3
Van Laak, V.4
Huber, S.5
Hocke, A.C.6
Opitz, B.7
Hoffmann, E.8
Kracht, M.9
Zerrahn, J.10
Hammerschmidt, S.11
Rosseau, S.12
Suttorp, N.13
Hippenstiel, S.14
-
26
-
-
33646588377
-
Pneumococci induced TLR- and Rac1-dependent NF-κB-recruitment to the IL-8 promoter in lung epithelial cells
-
DOI 10.1152/ajplung.00271.2005
-
Schmeck B, Huber S, Moog K, Zahlten J, Hocke AC, Opitz B, Hammerschmidt S, Mitchell TJ, Kracht M, Rosseau S, Suttorp N, Hippenstiel S: Pneumococci induced TLR-and Rac1-dependent NF-kappaB-recruitment to the IL-8 promoter in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2006;290:L730-L737. (Pubitemid 43725078)
-
(2006)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.290
, Issue.4
-
-
Schmeck, B.1
Huber, S.2
Moog, K.3
Zahlten, J.4
Hocke, A.C.5
Opitz, B.6
Hammerschmidt, S.7
Mitchell, T.J.8
Kracht, M.9
Rosseau, S.10
Suttorp, N.11
Hippenstiel, S.12
-
27
-
-
33746883220
-
A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium
-
DOI 10.1038/sj.gt.3302777, PII 3302777
-
Santel A, Aleku M, Keil O, Endruschat J, Esche V, Fisch G, Dames S, Loffer K, Fechtner M, Arnold W, Giese K, Klippel A, Kaufmann J: A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium. Gene Ther. 2006;13:1222-1234. (Pubitemid 44184716)
-
(2006)
Gene Therapy
, vol.13
, Issue.16
, pp. 1222-1234
-
-
Santel, A.1
Aleku, M.2
Keil, O.3
Endruschat, J.4
Esche, V.5
Fisch, G.6
Dames, S.7
Loffler, K.8
Fechtner, M.9
Arnold, W.10
Giese, K.11
Klippel, A.12
Kaufmann, J.13
-
28
-
-
0037384905
-
2-terminal kinase is essential for the regulation of AP-1 by tumor necrosis factor
-
DOI 10.1128/MCB.23.8.2871-2882.2003
-
Ventura JJ, Kennedy NJ, Lamb JA, Flavell RA, Davis RJ: c-Jun NH(2)-terminal kinase is essential for the regulation of AP-1 by tumor necrosis factor. Mol Cell Biol. 2003;23:2871-2882. (Pubitemid 36403084)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.8
, pp. 2871-2882
-
-
Ventura, J.-J.1
Kennedy, N.J.2
Lamb, J.A.3
Flavell, R.A.4
Davis, R.J.5
-
29
-
-
48849104512
-
The capsule sensitizes streptococcus pneumoniae to alpha-defensins human neutrophil proteins 1 to 3
-
Beiter K, Wartha F, Hurwitz R, Normark S, Zychlinsky A, Henriques-Normark B: The capsule sensitizes Streptococcus pneumoniae to alpha-defensins human neutrophil proteins 1 to 3. Infect Immun. 2008;76:3710-3716.
-
(2008)
Infect Immun
, vol.76
, pp. 3710-3716
-
-
Beiter, K.1
Wartha, F.2
Hurwitz, R.3
Normark, S.4
Zychlinsky, A.5
Henriques-Normark, B.6
-
30
-
-
33748670479
-
A functional dlt operon, encoding proteins required for incorporation of D-alanine in teichoic acids in gram-positive bacteria, confers resistance to cationic antimicrobial peptides in Streptococcus pneumoniae
-
DOI 10.1128/JB.00336-06
-
Kovacs M, Halfmann A, Fedtke I, Heintz M, Peschel A, Vollmer W, Hakenbeck R, Bruckner R: A functional dlt operon, encoding proteins required for incorporation of d-alanine in teichoic acids in gram-positive bacteria, confers resistance to cationic antimicrobial peptides in Streptococcus pneumoniae. J Bacteriol. 2006;188:5797-5805. (Pubitemid 44384087)
-
(2006)
Journal of Bacteriology
, vol.188
, Issue.16
, pp. 5797-5805
-
-
Kovacs, M.1
Halfmann, A.2
Fedtke, I.3
Heintz, M.4
Peschel, A.5
Vollmer, W.6
Hakenbeck, R.7
Bruckner, R.8
-
31
-
-
0141483491
-
Airway epithelia regulate expression of human beta-defensin 2 through toll-like receptor 2
-
Wang XF, Zhang ZF, Louboutin JP FAU, Moser C, Moser CF, Weiner DJ FAU, Wilson J, Wilson JM: Airway epithelia regulate expression of human beta-defensin 2 through Toll-like receptor 2. FASEB J. 2003;17:1727-1729.
-
(2003)
FASEB J.
, vol.17
, pp. 1727-1729
-
-
Wang, X.F.1
Zhang, Z.F.2
Louboutin, J.P.3
Moser, C.4
Moser, C.F.5
Weiners, D.J.6
Wilson, J.7
Wilson, J.M.8
-
32
-
-
34247607711
-
Importance of phosphoinositide 3-kinase γ in the host defense against pneumococcal infection
-
DOI 10.1164/rccm.200610-1533OC
-
Maus UA, Backi M, Winter C, Srivastava M, Schwarz MK, Ruckle T, Paton JC, Briles D, Mack M, Welte T, Maus R, Bohle RM, Seeger W, Rommel C, Hirsch E, Lohmeyer J, Preiss-ner KT: Importance of phosphoinositide 3-kinase gamma in the host defense against pneumococcal infection. Am J Respir Crit Care Med. 2007;175:958-966. (Pubitemid 46684707)
-
(2007)
American Journal of Respiratory and Critical Care Medicine
, vol.175
, Issue.9
, pp. 958-966
-
-
Maus, U.A.1
Backi, M.2
Winter, C.3
Srivastava, M.4
Schwarz, M.K.5
Ruckle, T.6
Paton, J.C.7
Briles, D.8
Mack, M.9
Welte, T.10
Maus, R.11
Bohle, R.M.12
Seeger, W.13
Rommel, C.14
Hirsch, E.15
Lohmeyer, J.16
Preissner, K.T.17
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