메뉴 건너뛰기




Volumn 79, Issue 3, 2012, Pages 198-203

Polymorphic variants of the IL2RA gene and susceptibility to type 1 diabetes in the Polish population

Author keywords

IL2RA gene; Single nucleotide polymorphism; Type 1 diabetes

Indexed keywords

INTERLEUKIN 2 RECEPTOR ALPHA;

EID: 84856597584     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/j.1399-0039.2011.01828.x     Document Type: Article
Times cited : (13)

References (42)
  • 1
    • 77951926420 scopus 로고    scopus 로고
    • Etiology of type 1 diabetes.
    • Todd JA. Etiology of type 1 diabetes. Immunity 2010: 32: 457-67.
    • (2010) Immunity , vol.32 , pp. 457-467
    • Todd, J.A.1
  • 2
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
    • Wellcome Trust Case Control Consortium.
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls. Nature 2007: 447: 661-78.
    • (2007) Nature , vol.447 , pp. 661-678
  • 3
    • 33745240931 scopus 로고    scopus 로고
    • A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region.
    • Smyth DJ, Cooper JD, Bailey R et al. A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nat Genet 2006: 38: 617-9.
    • (2006) Nat Genet , vol.38 , pp. 617-619
    • Smyth, D.J.1    Cooper, J.D.2    Bailey, R.3
  • 4
    • 67349199566 scopus 로고    scopus 로고
    • Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
    • Barrett JC, Clayton DG, Concannon P et al. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat Genet 2009: 41: 703-7.
    • (2009) Nat Genet , vol.41 , pp. 703-707
    • Barrett, J.C.1    Clayton, D.G.2    Concannon, P.3
  • 5
    • 27944505913 scopus 로고    scopus 로고
    • Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors.
    • Wang X, Rickert M, Garcia KC. Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors. Science 2005: 310: 1159-63.
    • (2005) Science , vol.310 , pp. 1159-1163
    • Wang, X.1    Rickert, M.2    Garcia, K.C.3
  • 7
    • 0033853625 scopus 로고    scopus 로고
    • Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation.
    • Kuniyasu Y, Takahashi T, Itoh M, Shimizu J, Toda G, Sakaguchi S. Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation. Int Immunol 2000: 12: 1145-55.
    • (2000) Int Immunol , vol.12 , pp. 1145-1155
    • Kuniyasu, Y.1    Takahashi, T.2    Itoh, M.3    Shimizu, J.4    Toda, G.5    Sakaguchi, S.6
  • 8
    • 0028784289 scopus 로고
    • Interelukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment.
    • Willerford DM, Chen J, Ferry JA, Davidson L, Ma A, Alt FW. Interelukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity 1995: 3: 521-30.
    • (1995) Immunity , vol.3 , pp. 521-530
    • Willerford, D.M.1    Chen, J.2    Ferry, J.A.3    Davidson, L.4    Ma, A.5    Alt, F.W.6
  • 9
    • 0030903027 scopus 로고    scopus 로고
    • Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor.
    • Sharfe N, Dadi HK, Shshar M, Roifman CM. Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor. Proc Natl Acad Sci USA 1997: 94: 3168-71.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3168-3171
    • Sharfe, N.1    Dadi, H.K.2    Shshar, M.3    Roifman, C.M.4
  • 10
    • 33846805925 scopus 로고    scopus 로고
    • CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enetropathy, X-linked-like syndrome, and defective IL-10 expression from CD4 lymphocytes.
    • Caudy AA, Reddy ST, Chatila T, Atkinson JP, Verbsky JW. CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enetropathy, X-linked-like syndrome, and defective IL-10 expression from CD4 lymphocytes. J Allergy Clin Immunol 2007: 119: 482-7.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 482-487
    • Caudy, A.A.1    Reddy, S.T.2    Chatila, T.3    Atkinson, J.P.4    Verbsky, J.W.5
  • 11
    • 20244373351 scopus 로고    scopus 로고
    • Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms.
    • Vella A, Cooper JD, Lowe CE et al. Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms. Am J Hum Genet 2005: 76: 773-9.
    • (2005) Am J Hum Genet , vol.76 , pp. 773-779
    • Vella, A.1    Cooper, J.D.2    Lowe, C.E.3
  • 12
    • 34548299105 scopus 로고    scopus 로고
    • Risk alleles for multiple sclerosis identified by a genome wide study.
    • International Multiple Sclerosis Genetics Consortium;
    • International Multiple Sclerosis Genetics Consortium; Hafler DA, Compston A, Sawcer S et al. Risk alleles for multiple sclerosis identified by a genome wide study. N Engl J Med 2007: 357: 851-62.
    • (2007) N Engl J Med , vol.357 , pp. 851-862
    • Hafler, D.A.1    Compston, A.2    Sawcer, S.3
  • 13
    • 77952888454 scopus 로고    scopus 로고
    • Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
    • Stahl EA, Raychudhuri S, Remmers EF et al. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet 2010: 42: 508-14.
    • (2010) Nat Genet , vol.42 , pp. 508-514
    • Stahl, E.A.1    Raychudhuri, S.2    Remmers, E.F.3
  • 14
    • 34548367511 scopus 로고    scopus 로고
    • Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.
    • Lowe CE, Cooper JD, Brusko T et al. Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes. Net Genet 2007: 39: 1074-82.
    • (2007) Net Genet , vol.39 , pp. 1074-1082
    • Lowe, C.E.1    Cooper, J.D.2    Brusko, T.3
  • 15
    • 33947274768 scopus 로고    scopus 로고
    • Association of the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs.
    • Brand OJ, Lowe CE, Heward JM et al. Association of the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs. Clin Endocrinol (Oxf) 2007: 66: 508-12.
    • (2007) Clin Endocrinol (Oxf) , vol.66 , pp. 508-512
    • Brand, O.J.1    Lowe, C.E.2    Heward, J.M.3
  • 16
    • 63449102458 scopus 로고    scopus 로고
    • Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis.
    • Carr EJ, Clatworthy MR, Lowe CE et al. Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis. BMC Med Genet 2009: 10: 22.
    • (2009) BMC Med Genet , vol.10 , pp. 22
    • Carr, E.J.1    Clatworthy, M.R.2    Lowe, C.E.3
  • 17
    • 58249113834 scopus 로고    scopus 로고
    • Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis.
    • Hinks A, Ke X, Barton A et al. Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis. Arthritis Rheum 2009: 60: 251-7.
    • (2009) Arthritis Rheum , vol.60 , pp. 251-257
    • Hinks, A.1    Ke, X.2    Barton, A.3
  • 18
    • 58949100205 scopus 로고    scopus 로고
    • IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.
    • Maier LM, Lowe CE, Cooper J et al. IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. PLoS Genet 2009: 5: e1000322.
    • (2009) PLoS Genet , vol.5
    • Maier, L.M.1    Lowe, C.E.2    Cooper, J.3
  • 19
    • 34047118563 scopus 로고    scopus 로고
    • Toward further mapping of the association between the IL2RA locus and type 1 diabetes.
    • Qu HQ, Montpetit A, Ge B, Hudson TJ, Polychronakos C. Toward further mapping of the association between the IL2RA locus and type 1 diabetes. Diabetes 2007: 56: 1174-6.
    • (2007) Diabetes , vol.56 , pp. 1174-1176
    • Qu, H.Q.1    Montpetit, A.2    Ge, B.3    Hudson, T.J.4    Polychronakos, C.5
  • 20
    • 51749098572 scopus 로고    scopus 로고
    • Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency.
    • Skinningsrud B, Husebye ES, Pearce SH et al. Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency. J Clin Endocrinol Metab 2008: 93: 3310-7.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3310-3317
    • Skinningsrud, B.1    Husebye, E.S.2    Pearce, S.H.3
  • 21
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: analysis and visualisation of LD and haplotype maps.
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualisation of LD and haplotype maps. Bioinformatics 2005: 21: 263-5.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 22
    • 79958000168 scopus 로고    scopus 로고
    • No evidence for association of the polymorphisms in NLPR1 gene with type 1 diabetes in Poland.
    • Zurawek M, Fichna M, Fichna P, Januszkiewicz D, Nowak J. No evidence for association of the polymorphisms in NLPR1 gene with type 1 diabetes in Poland. Diabetes Res Clin Pract 2011: 92: e49-51.
    • (2011) Diabetes Res Clin Pract , vol.92
    • Zurawek, M.1    Fichna, M.2    Fichna, P.3    Januszkiewicz, D.4    Nowak, J.5
  • 23
    • 78651112432 scopus 로고    scopus 로고
    • PTPN22, PDCD1 and CYP27B1 polymorphisms and susceptibility to type 1 diabetes in Polish patients.
    • Fichna M, Zurawek M, Januszkiewicz-Lewandowska D, Fichna P, Nowak J. PTPN22, PDCD1 and CYP27B1 polymorphisms and susceptibility to type 1 diabetes in Polish patients. Int J Immunogenet 2010: 37: 367-72.
    • (2010) Int J Immunogenet , vol.37 , pp. 367-372
    • Fichna, M.1    Zurawek, M.2    Januszkiewicz-Lewandowska, D.3    Fichna, P.4    Nowak, J.5
  • 24
    • 75649120798 scopus 로고    scopus 로고
    • Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.
    • Type I Diabetes Genetics Consortium. (Suppl 1)
    • Howson JM, Walker NM, Smyth DJ, Todd JA. Type I Diabetes Genetics Consortium. Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families. Genes Immun 2009: 10 (Suppl 1): S74-84.
    • (2009) Genes Immun , vol.10
    • Howson, J.M.1    Walker, N.M.2    Smyth, D.J.3    Todd, J.A.4
  • 25
    • 62349109262 scopus 로고    scopus 로고
    • Genetic association between the interleukin-2 receptor-alpha gene and mode of onset of type 1 diabetes in the Japanese population.
    • Kawasaki E, Awata T, Ikegami H et al. Genetic association between the interleukin-2 receptor-alpha gene and mode of onset of type 1 diabetes in the Japanese population. J Clin Endocrinol Metab 2009: 94: 947-52.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 947-952
    • Kawasaki, E.1    Awata, T.2    Ikegami, H.3
  • 26
    • 75649098698 scopus 로고    scopus 로고
    • The type I diabetes association of the IL2RA locus.
    • Suppl 1
    • Qu HQ, Bradfield JP, Belisle A et al. The type I diabetes association of the IL2RA locus. Genes Immun 2009: 10 (Suppl 1): S42-8.
    • (2009) Genes Immun , vol.10
    • Qu, H.Q.1    Bradfield, J.P.2    Belisle, A.3
  • 27
    • 76249129135 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms in the IL2RA gene are associated with age at diagnosis in late-onset Finnish type 1 diabetes subjects.
    • Klinker MW, Schiller JJ, Magnuson VL et al. Single-nucleotide polymorphisms in the IL2RA gene are associated with age at diagnosis in late-onset Finnish type 1 diabetes subjects. Immunogenetics 2010: 62: 101-7.
    • (2010) Immunogenetics , vol.62 , pp. 101-107
    • Klinker, M.W.1    Schiller, J.J.2    Magnuson, V.L.3
  • 28
    • 0033867396 scopus 로고    scopus 로고
    • Genetic, autoimmune, and clinical characteristics of childhood- and adult-onset type 1 diabetes.
    • Sabbah E, Savola K, Ebeling T et al. Genetic, autoimmune, and clinical characteristics of childhood- and adult-onset type 1 diabetes. Diabetes Care 2000: 23: 1326-32.
    • (2000) Diabetes Care , vol.23 , pp. 1326-1332
    • Sabbah, E.1    Savola, K.2    Ebeling, T.3
  • 29
    • 0345505676 scopus 로고    scopus 로고
    • Genetic liability of type 1 diabetes and the onset age among 22,650 young Finnish twin pairs: a nationwide follow-up study.
    • Hyttinen V, Kaprio J, Kinnunen L et al. Genetic liability of type 1 diabetes and the onset age among 22, 650 young Finnish twin pairs: a nationwide follow-up study. Diabetes 2003: 52: 1052.
    • (2003) Diabetes , vol.52 , pp. 1052
    • Hyttinen, V.1    Kaprio, J.2    Kinnunen, L.3
  • 30
    • 78149411413 scopus 로고    scopus 로고
    • Association of IL-2RA/CD25 with type 1 diabetes in the Belgian population.
    • Aminkeng F, Weets I, Van Autreve JE et al. Association of IL-2RA/CD25 with type 1 diabetes in the Belgian population. Hum Immunol 2010: 71: 1233-7.
    • (2010) Hum Immunol , vol.71 , pp. 1233-1237
    • Aminkeng, F.1    Weets, I.2    Van Autreve, J.E.3
  • 31
    • 33947546815 scopus 로고    scopus 로고
    • Analysis of the Fc receptor-like-3 (FCRL3) locus in Caucasians with autoimmune disorders suggests a complex pattern of disease association.
    • Owen CJ, Kelly H, Eden JA, Merriman ME, Perace SH, Merriman TR. Analysis of the Fc receptor-like-3 (FCRL3) locus in Caucasians with autoimmune disorders suggests a complex pattern of disease association. J Clin Endocrinol Metab 2007: 92: 1106-11.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1106-1111
    • Owen, C.J.1    Kelly, H.2    Eden, J.A.3    Merriman, M.E.4    Perace, S.H.5    Merriman, T.R.6
  • 32
    • 69349102624 scopus 로고    scopus 로고
    • Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource.
    • Dendrou CA, Plagnol V, Fung E et al. Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource. Net Genet 2009: 41: 1011-5.
    • (2009) Net Genet , vol.41 , pp. 1011-1015
    • Dendrou, C.A.1    Plagnol, V.2    Fung, E.3
  • 33
    • 33750219508 scopus 로고    scopus 로고
    • Both integrated and differential regulation of components of the IL-2/IL-2 receptor system.
    • Kim HP, Imbert J, Leonard WJ. Both integrated and differential regulation of components of the IL-2/IL-2 receptor system. Cytokine Growth Factor Rev 2006: 17: 349-66.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 349-366
    • Kim, H.P.1    Imbert, J.2    Leonard, W.J.3
  • 34
    • 0025490104 scopus 로고    scopus 로고
    • The molecular basis for the generation of the human soluble interleukin 2 receptor.
    • Rubin LA, Galli F, Greene WC, Nelson DL, Jay G. The molecular basis for the generation of the human soluble interleukin 2 receptor. Cytokine 1999: 2: 330-6.
    • (1999) Cytokine , vol.2 , pp. 330-336
    • Rubin, L.A.1    Galli, F.2    Greene, W.C.3    Nelson, D.L.4    Jay, G.5
  • 36
    • 0023709262 scopus 로고
    • Increased soluble interleukin-2 receptor levels in the sera of type 1 diabetic patients.
    • Giordano C, Galluzzo A, Marco A et al. Increased soluble interleukin-2 receptor levels in the sera of type 1 diabetic patients. Diabetes Res 1988: 8: 135-8.
    • (1988) Diabetes Res , vol.8 , pp. 135-138
    • Giordano, C.1    Galluzzo, A.2    Marco, A.3
  • 37
    • 0028870119 scopus 로고
    • Soluble interleukin 2 receptor levels in children with type I insulin-dependent diabetes mellitus.
    • Gertner LA, Pfeifer MC, Albini C, Francis GL. Soluble interleukin 2 receptor levels in children with type I insulin-dependent diabetes mellitus. Ann Clin Lab Sci 1995: 25: 44-51.
    • (1995) Ann Clin Lab Sci , vol.25 , pp. 44-51
    • Gertner, L.A.1    Pfeifer, M.C.2    Albini, C.3    Francis, G.L.4
  • 38
    • 49549098143 scopus 로고    scopus 로고
    • The exon-3-encoded domain of IL-15Ralpha contributes to IL-15 high-affinity binding and is crucial for the IL-15 antagonistic effect of soluble IL-15Ralpha.
    • Bouchard G, Garrigue-Antar L, Sole V et al. The exon-3-encoded domain of IL-15Ralpha contributes to IL-15 high-affinity binding and is crucial for the IL-15 antagonistic effect of soluble IL-15Ralpha. J Mol Biol 2008: 382: 1-12.
    • (2008) J Mol Biol , vol.382 , pp. 1-12
    • Bouchard, G.1    Garrigue-Antar, L.2    Sole, V.3
  • 39
    • 63149109244 scopus 로고    scopus 로고
    • Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses.
    • Maier LM, Anderson DE, Severson CA et al. Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses. J Immunol 2009: 182: 1541-7.
    • (2009) J Immunol , vol.182 , pp. 1541-1547
    • Maier, L.M.1    Anderson, D.E.2    Severson, C.A.3
  • 40
    • 1842732224 scopus 로고    scopus 로고
    • Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis.
    • Viglietta V, Baecher-Allan C, Weiner HL, Hafler DA. Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med 2004: 199: 971-9.
    • (2004) J Exp Med , vol.199 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 41
    • 33845691031 scopus 로고    scopus 로고
    • A mini meta-analysis of studies on CD4+CD25+ T cells in human type 1 diabetes: report of the Immunology of Diabetes Society T Cell Workshop.
    • Tree TI, Roep BO, Peakman M. A mini meta-analysis of studies on CD4+CD25+ T cells in human type 1 diabetes: report of the Immunology of Diabetes Society T Cell Workshop. Ann N Y Acad Sci 2006: 1079: 9-18.
    • (2006) Ann N Y Acad Sci , vol.1079 , pp. 9-18
    • Tree, T.I.1    Roep, B.O.2    Peakman, M.3
  • 42
    • 2442628376 scopus 로고    scopus 로고
    • Defective suppressor function of human CD4+CD25+ regulatory T cells in autoimmune polyglandular syndrome type II.
    • Kriegel MA, Lohman T, Gabler C, Blank N, Kalden JR, Lorenz HM. Defective suppressor function of human CD4+CD25+ regulatory T cells in autoimmune polyglandular syndrome type II. J Exp Med 2004: 199: 1285-91.
    • (2004) J Exp Med , vol.199 , pp. 1285-1291
    • Kriegel, M.A.1    Lohman, T.2    Gabler, C.3    Blank, N.4    Kalden, J.R.5    Lorenz, H.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.