The Exon-3-Encoded Domain of IL-15Rα Contributes to IL-15 High-Affinity Binding and Is Crucial for the IL-15 Antagonistic Effect of Soluble IL-15Rα

Journal of Molecular Biology

Volumn 382, Issue 1, 2008, Pages 1-12

  Bouchaud, Grégory ^a,b   Garrigue Antar, Laure ^a,b   Solé, Véronique ^a,b   Quéméner, Agnès ^a,b   Boublik, Yvan ^c   Mortier, Erwan ^a,b   Perdreau, Harmonie ^a,b   Jacques, Yannick ^a,b   Plet, Ariane ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE NANTES   (France)

^c Centre National de la Recherche Scientifique   (France)

Author keywords

antagonist; fusion protein; interleukin 15; receptor; sushi domain

Indexed keywords

HYBRID PROTEIN; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 15 RECEPTOR ALPHA; INTERLEUKIN 15 RECEPTOR BETA; INTERLEUKIN 15 RECEPTOR GAMMA;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; COVALENT BOND; EXON; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; RECEPTOR INTRINSIC ACTIVITY;

EID: 49549098143     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.07.019     Document Type: Article

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