Macrophages have no lineage history of Foxp3 expression

Blood

Volumn 119, Issue 5, 2012, Pages 1316-1318

  Put, Stéphanie ^a   Avau, Anneleen ^a   Humblet Baron, Stéphanie ^b,c   Schurgers, Evelien ^a   Liston, Adrian ^b   Matthys, Patrick ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; COLLAGEN; COLONY STIMULATING FACTOR 1; CRE RECOMBINASE; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; INTERLEUKIN 4; MESSENGER RNA; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; AUTOFLUORESCENCE; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL CULTURE; CELL LINEAGE; FLOW CYTOMETRY; IMMUNIZATION; IN VIVO STUDY; LETTER; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SPLEEN CELL; TRANSGENIC ANIMAL;

EID: 84856593973     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-11-391755     Document Type: Letter

References (10)

1. Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science. 2003;299(5609):1057-1061. (Pubitemid 36222930)
2. Chang X, Gao JX, Jiang Q et al. The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis. J Exp Med. 2005;202(8):1141-1151. (Pubitemid 41464507)
3. Zuo T, Wang L, Morrison C et al. FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene. Cell. 2007;129(7):1275-1286. (Pubitemid 46970708)
4. Chen GY, Chen C, Wang L et al. Cutting edge: Broad expression of the FoxP3 locus in epithelial cells: a caution against early interpretation of fatal inflammatory diseases following in vivo depletion of FoxP3-expressing cells. J Immunol. 2008;180(8):5163-5166.
5. Kim J, Lahl K, Hori S et al. Cutting edge: depletion of Foxp3+ cells leads to induction of autoimmunity by specific ablation of regulatory T cells in genetically targeted mice. J Immunol. 2009;183(12):7631-7634.
6. Liston A, Farr AG, Chen Z et al. Lack of Foxp3 function and expression in the thymic epithelium. J Exp Med. 2007;204(3):475-480. (Pubitemid 46457071)
7. Manrique SZ, Correa MA, Hoelzinger DB et al. Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth. J Exp Med. 2011;208(12):2561.
8. De Klerck B, Carpentier I, Lories RJ et al. Enhanced osteoclast development in collagen-induced arthritis in interferon-gamma receptor knock-out mice as related to increased splenic CD11b+ myelopoiesis. Arthritis Res Ther. 2004;6(3):R220-R231.
9. Ho VW, Sly LM. Derivation and characterization of murine alternatively activated (M2) macrophages. Methods Mol Biol. 2009;531:173-85.
10. Baumgarth N, Roederer M. A practical approach to multicolor flow cytometry for immunophenotyping. J Immunol Methods. 2000;243(1-2):77-97.