Efficient capture of Candida albicans and zymosan by SIGNR1 augments TLR2-dependent TNF-α production

International Immunology

Volumn 24, Issue 2, 2012, Pages 89-96

  Takahara, Kazuhiko ^a   Tokieda, Sumika ^a   Nagaoka, Koji ^a   Inaba, Kayo ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

C. albicans; Lectin; Macrophages; SIGNR1; TLR2; Zymosan

Indexed keywords

DECTIN 1; LAMINARAN; LECTIN; SIGNR1 PROTEIN; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZYMOSAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIUM IDENTIFICATION; BINDING AFFINITY; CANDIDA ALBICANS; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IN VITRO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN MOTIF; TREATMENT RESPONSE;

EID: 84856587365     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxr103     Document Type: Article

References (35)

1. Janeway, C. A. Jr 1989. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54:1.
2. Gay, N. J. and Gangloff, M. 2007. Structure and function of toll receptors and their ligands. Annu. Rev. Biochem. 76:141.
3. Kawai, T. and Akira, S. 2010. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11:373.
4. Osorio, F. and Reis, E. S. C. 2011. Myeloid C-type lectin receptors in pathogen recognition and host defense. Immunity 34:651.
5. Figdor, C. G., van Kooyk, Y. and Adema, G. J. 2002. C-type lectin receptors on dendritic cells and Langerhans cells. Nat. Rev. Immunol. 2:77.
6. Willment, J. A. and Brown, G. D. 2008. C-type lectin receptors in antifungal immunity. Trends Microbiol. 16:27.
7. Geijtenbeek, T. B. H. and Gringhuis, S. I. 2009. Signalling through C-type lectin receptors: shaping immune responses. Nat. Rev. Immunol. 9:465.
8. Ariizumi, K., Shen, G. L., Shikano, S. et al. 2000. Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning. J. Biol. Chem. 275:20157.
9. Geijtenbeek, T. B., Torensma, R., van Vliet, S. J. et al. 2000. Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses. Cell 100:575.
10. Brown, G. D., Herre, J., Williams, D. L., Willment, J. A., Marshall, A. S. and Gordon, S. 2003. Dectin-1 mediates the biological effects of beta-glucans. J. Exp. Med. 197:1119.
11. Goodridge, H. S., Wolf, A. J. and Underhill, D. M. 2009. Betaglucan recognition by the innate immune system. Immunol. Rev. 230:38.
12. Gringhuis, S. I., den Dunnen, J., Litjens, M. et al. 2009. Dectin-1 directs T helper cell differentiation by controlling noncanonical NFkappaB activation through Raf-1 and Syk. Nat. Immunol. 10:203.
13. LeibundGut-Landmann, S., Gross, O., Robinson, M. J. et al. 2007. Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat. Immunol. 8:630.
14. McGreal, E. P., Miller, J. L. and Gordon, S. 2005. Ligand recognition by antigen-presenting cell C-type lectin receptors. Curr. Opin. Immunol. 17:18.
15. Trinchieri, G. and Sher, A. 2007. Cooperation of Toll-like receptor signals in innate immune defence. Nat. Rev. Immunol. 7:179.
16. Gantner, B. N., Simmons, R. M., Canavera, S. J., Akira, S. and Underhill, D. M. 2003. Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J. Exp. Med. 197:1107.
17. Shin, D. M., Yang, C. S., Yuk, J. M. et al. 2008. Mycobacterium abscessus activates the macrophage innate immune response via a physical and functional interaction between TLR2 and dectin-1. Cell. Microbiol. 10:1608.
18. Gringhuis, S. I., den Dunnen, J., Litjens, M., van der Vlist, M. and Geijtenbeek, T. B. 2009. Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori. Nat. Immunol. 10:1081.
19. Hovius, J. W., de Jong, M. A., den Dunnen, J. et al. 2008. Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization. PLoS Pathog. 4:e31.
20. Park, C. G., Takahara, K., Umemoto, E. et al. 2001. Five mouse homologues of the human dendritic cell C-type lectin, DC-SIGN. Int. Immunol. 13:1283.
21. Powlesland, A. S., Ward, E. M., Sadhu, S. K., Guo, Y., Taylor, M. E. and Drickamer, K. 2006. Widely divergent biochemical properties of the complete set of mouse DC-SIGN-related proteins. J. Biol. Chem. 281:20440.
22. Takahara, K., Yashima, Y., Omatsu, Y. et al. 2004. Functional comparison of the mouse DC-SIGN, SIGNR1, SIGNR3 and Langerin, C-type lectins. Int. Immunol. 16:819.
23. Kang, Y. S., Kim, J. Y., Bruening, S. A. et al. 2004. The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide of Streptococcus pneumoniae in the marginal zone of mouse spleen. Proc. Natl Acad. Sci. USA 101:215.
24. Gonzalez, S. F., Lukacs-Kornek, V., Kuligowski, M. P. et al. 2010. Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes. Nat. Immunol. 11:427.
25. Zhou, Y., Kawasaki, H., Hsu, S. C. et al. 2010. Oral tolerance to food-induced systemic anaphylaxis mediated by the C-type lectin SIGNR1. Nat. Med. 16:1128.
26. Kang, Y. S., Do, Y., Lee, H. K. et al. 2006. A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q. Cell 125:47.
27. Takahara, K., Tokieda, S., Nagaoka, K., Takeda, T., Kimura, Y. and Inaba, K. 2011. C-type lectin SIGNR1 enhances cellular oxidative burst response against C. albicans in cooperation with Dectin-1. Eur. J. Immunol. 41:1435.
28. Nagaoka, K., Takahara, K., Tanaka, K. et al. 2005. Association of SIGNR1 with TLR4-MD-2 enhances signal transduction by recognition of LPS in gram-negative bacteria. Int. Immunol. 17:827.
29. Kang, Y. S., Yamazaki, S., Iyoda, T. et al. 2003. SIGN-R1, a novel C-type lectin expressed by marginal zone macrophages in spleen, mediates uptake of the polysaccharide dextran. Int. Immunol. 15:177.
30. Underhill, D. M., Ozinsky, A., Hajjar, A. M. et al. 1999. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 401:811.
31. Geijtenbeek, T. B., van Duijnhoven, G. C., van Vliet, S. J. et al. 2002. Identification of different binding sites in the dendritic cellspecific receptor DC-SIGN for intercellular adhesion molecule 3 and HIV-1. J. Biol. Chem. 277:11314.
32. Taylor, P. R., Brown, G. D., Herre, J., Williams, D. L., Willment, J. A. and Gordon, S. 2004. The role of SIGNR1 and the beta-glucan receptor (dectin-1) in the nonopsonic recognition of yeast by specific macrophages. J. Immunol. 172:1157.
33. Numazaki, M., Kato, C., Kawauchi, Y., Kajiwara, T., Ishii, M. and Kojima, N. 2009. Cross-linking of SIGNR1 activates JNK and induces TNF-a production in RAW264.7 cells that express SIGNR1. Biochem. Biophys. Res. Commun. 386:202.
34. Kato, C. and Kojima, N. 2010. SIGNR1 ligation on murine peritoneal macrophages induces IL-12 production through NFkappaB activation. Glycoconj. J. 27:525.
35. Feinberg, H., Guo, Y., Mitchell, D. A., Drickamer, K. and Weis, W. I. 2005. Extended neck regions stabilize tetramers of the receptors DC-SIGN and DC-SIGNR. J. Biol. Chem. 280:1327.