Determination of paraquat and diquat in human body fluids by high-performance liquid chromatography/tandem mass spectrometry

Journal of Mass Spectrometry

Volumn 39, Issue 10, 2004, Pages 1147-1152

  Lee, Xiao Pen ^a   Kumazawa, Takeshi ^a   Fujishiro, Masaya ^a   Hasegawa, Chika ^a   Arinobu, Tetsuya ^b   Seno, Hiroshi ^b   Ishii, Akira ^c   Sato, Keizo ^a  

^a SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Diquat; High performance liquid chromatography; Paraquat; Tandem mass spectrometry

Indexed keywords

BLOOD; BODY FLUIDS; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION; REACTION KINETICS; SEPARATION;

ELECTROSPRAY IONIZATION (ESI); SELECTIVE REACTION MONITORING (SRM);

MASS SPECTROMETRY;

ACETONITRILE; AMMONIUM ACETATE; BUTYRIC ACID DERIVATIVE; DIQUAT; PARAQUAT;

ACCURACY; ARTICLE; BLOOD ANALYSIS; BODY FLUID; CALIBRATION; CHEMICAL ANALYSIS; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; CONTROLLED STUDY; ELUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; ION PAIR EXTRACTION; LINEAR SYSTEM; MALE; NONHUMAN; POSITIVE ION ELECTROSPRAY; PRIORITY JOURNAL; PROCESS MONITORING; RAT; SENSITIVITY ANALYSIS; SEPARATION TECHNIQUE; STANDARDIZATION; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY; URINALYSIS; VALIDATION PROCESS;

ANIMALS; BODY FLUIDS; CHEMISTRY, CLINICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIQUAT; HERBICIDES; HUMANS; MASS SPECTROMETRY; PARAQUAT; RATS;

EID: 6944219782     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/jms.695     Document Type: Article

References (28)

1. Fairshter RD, Wilson AF. Paraquat poisoning: manifestations and therapy. Am. J. Med. 1975; 59: 751.
2. Okonek S. Paraquat and diquat poisoning. Toxicologic findings and new therapeutic possibilities. Med. Welt 1976; 27: 1401.
3. Haley TJ. Review of the toxicology of paraquat (1,1′-dimethyl-4,4′-bipyridinium chloride). Clin. Toxicol. 1979; 14: 1.
4. Vanholder R, Colardyn F, Reuck JD, Praet M, Lameire N, Ringoir S. Diquat intoxication: report of two cases and review of the literature. Am. J. Med. 1981; 70: 1267.
5. Ludwig-Kohn H, Sziedat A, Matthaei D, Henning HV. Analysis of neutral steroid sulfates by glass capillary gas chromatography-mass spectrometry (GC-MS) from blood of a patient with paraquat poisoning. Clin. Chim. Acta 1982; 121: 189.
6. Mahieu P, Bonduelle Y, DeCabooter A, Gala M, Hassoun A, Koening J, Lauwerys R. Acute diquat intoxication. Interest of its repeated determination in urine and the evaluation of renal proximal tubule integrity. J. Toxicol. Clin. Toxicol. 1984; 22: 363.
7. Smith CV. Effect of BCNU pretreatment on diquat-induced oxidant stress and hepatotoxicity. Biochem. Biophys. Res. Commun. 1987; 144: 415.
8. Kawase S, Kanno S, Ukai S. Determination of the herbicides paraquat and diquat in blood and urine by gas chromatography. J. Chromatogr. 1984; 283: 231.
9. Gill R, Qua SC, Moffat AC. High-performance liquid chromatography of paraquat and diquat in urine with rapid sample preparation involving ion-pair extraction on disposable cartridges of octadecyl-silica. J. Chromatogr. 1983; 255: 483.
10. Tsunoda N, Ootsuru O. Detection and confirmation of paraquat and diquat by capillary gas chromatography/mass spectrometry and capillary gas chromatography/fourier transform infrared spectrometry. Eisei Kagaku 1989; 35: 73.
11. Tsuchihashi H, Tatsuno M, Otsuki K. Simultaneous determination of paraquat and diquat in blood and urine by high performance liquid chromatography utilizing their oxidation products. Rep. Natl. Res. Inst. Police Sci. 1988; 41: 269.
12. Chichila TM, Walters SM. Liquid chromatographic determination of paraquat and diquat in crops using a silica column with aqueous ionic mobile phase. J. Assoc. Off. Anal. Chem. 1991; 74: 961.
13. Ito S, Nagata T, Kudo K, Kimura K, Imamura T. Simultaneous determination of paraquat and diquat in human tissues by high-performance liquid chromatography. J. Chromatogr. 1993; 617: 119.
14. Itagaki T, Lai SJ, Binder SR. A rapid monitoring method of paraquat and diquat in serum and urine using ion-pairing bare-silica stationary phase HPLC following a single acidification step of sample pretreatment. J. Liq. Chromatogr. Relat. Technol. 1997; 20: 3339.
15. Madhu C, Gregus Z, Klaassen CD. Simple method for analysis of diquat in biological fluids and tissues by high-performance liquid chromatography. J. Chromatogr. B 1995; 674: 193.
16. Marr JC, King JB. A simple high performance liquid chromatography/ionspray tandem mass spectrometry method for the direct determination of paraquat and diquat in water. Rapid Commun. Mass Spectrom. 1997; 11: 479.
17. Kage S, Kudo K, Fukushima S, Ikeda N. Selective determination of paraquat and diquat in blood by high-performance liquid chromatography and high-performance liquid chromatography/mass spectrometry. Jpn. J. Forensic Toxicol. 1998; 16: 34.
18. Carneiro MC, Puignou L, Galceran MT. Comparison of capillary electrophoresis and reversed-phase ion-pair high-performance liquid chromatography for the determination of paraquat, diquat and difenzoquat. J. Chromatogr. A 1994; 669: 217.
19. Núñez O, Moyano E, Puignou L, Galceran MT. Sample stacking with matrix removal for the determination of paraquat, diquat and difenzoquat in water by capillary electrophoresis. J. Chromatogr. A 2001; 912: 353.
20. Núñez O, Moyano E, Galceran MT. Solid-phase extraction and sample stacking-capillary electrophoresis for the determination of quaternary ammonium herbicides in drinking water. J. Chromatogr. A 2002; 946: 275.
21. Núñez O, Moyano E, Galceran MT. Capillary electrophoresis-mass spectrometry for the analysis of quaternary ammonium herbicides. J. Chromatogr. A 2002; 974: 243.
22. Castro R, Moyano E, Galceran MT. On-pair liquid chromatography-atmospheric pressure ionization mass spectrometry for the determination of quaternary ammonium herbicides. J. Chromatogr. A 1999; 830: 145.
23. Aravagiri M, Marder SR. Simultaneous determination of risperidone and 9-hydroxyrisperidone in plasma by liquid chromatography/electrospray tandem mass spectrometry. J. Mass Spectrom. 2000; 35: 718.
24. Kumazawa T, Seno H, Watanabe-Suzuki K, Hattori H, Ishii A, Sato K, Suzuki O. Determination of phenothiazines in human body fluids by solid-phase microextraction and liquid chromatography/tandem mass spectrometry. J. Mass Spectrom. 2000; 35: 1091.
25. Josefsson M, Kronstrand R, Andersson J, Roman M. Evaluation of electrospray ionisation liquid chromatography-tandem mass spectrometry for rational determination of a number of neuroleptics and their major metabolites in human body fluids and tissues. J. Chromatogr. B 2003; 789: 151.
26. Stokvis E, Rosing H, Crul M, Rieser MJ, Heck AJR, Schellens JHM, Beijnen JH. Quantitative analysis of the novel anticancer drug ABT-518, a matrix metalloproteinase inhibitor, plus the screening of six metabolites in human plasma using high-performance liquid chromatography coupled with electrospray tandem mass spectrometry. J. Mass Spectrom. 2004; 39: 277.
27. Song XB, Budde WL. Capillary Electrophoresis-Electrospray Mass Spectra of the Herbicides Paraquat and Diquat. J. Am. Soc. Mass Spectrom. 1996; 7: 981.
28. Guan F, Uboh C, Soma L, Hess A, Luo Y, Tsang DS. Sensitive liquid chromatographic/tandem mass spectrometric method for the determination of beclomethasone dipropionate and its metabolites in equine plasma and urine. J. Mass Spectrom. 2003; 38: 823.