Mechanisms of ectopic bone formation by human osteoprogenitor cells on CaP biomaterial carriers

Biomaterials

Volumn 33, Issue 11, 2012, Pages 3127-3142

  Chai, Yoke Chin ^a,b   Roberts, Scott J ^a   Desmet, Eline ^a   Kerckhofs, Greet ^a   van Gastel, Nick ^a   Geris, Liesbet ^a,c   Carmeliet, Geert ^a   Schrooten, Jan ^a   Luyten, Frank P ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF MALAYA   (Malaysia)

^c UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Calcium phosphate; Ectopic bone formation; Mesenchymal stem cells; Osteogenic differentiation; Stem cell host material interaction

Indexed keywords

BONE REGENERATION; CELL-BASED; COLLAGEN MATRICES; CULTURE CONDITIONS; ECTOPIC BONES; HUMAN OSTEOPROGENITOR; IN-SITU; IN-VITRO; IN-VIVO; MECHANISM OF ACTION; MESENCHYMAL STEM CELL; MICROFOCUS X-RAY COMPUTED TOMOGRAPHY; MULTI VARIATE ANALYSIS; NON-PREDICTABILITY; OSTEOCALCIN; OSTEOGENIC; OSTEOGENIC DIFFERENTIATION; OSTEOPONTIN; OSTERIX; PARTIAL LEAST SQUARE REGRESSION; PRE-CONDITIONING; STEM CELL-HOST-MATERIAL INTERACTION; UP-REGULATION;

BIOLOGICAL MATERIALS; BIOMATERIALS; BIOMIMETICS; CALCIUM; CALCIUM PHOSPHATE; CELL CULTURE; CELL PROLIFERATION; COMPUTERIZED TOMOGRAPHY; GENE EXPRESSION; STEM CELLS;

BONE;

BIOMATERIAL; BONE MORPHOGENETIC PROTEIN 2; CALCIUM PHOSPHATE; OSTEOCALCIN; OSTEOPONTIN; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE CELL; CELL CULTURE; CELL PROLIFERATION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; ECTOPIC BONE FORMATION; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; OSSIFICATION; PERIOSTEUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; X RAY;

ADOLESCENT; BIOCOMPATIBLE MATERIALS; BONE DEVELOPMENT; CALCIUM PHOSPHATES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; FEMALE; HUMANS; MALE; MATERIALS TESTING; OSTEOBLASTS; OSTEOGENESIS; STEM CELLS; TISSUE ENGINEERING;

EID: 84856573550     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.01.015     Document Type: Article

References (35)

1. Shapiro F. Bone development and its relation to fracture repair. The role of mesenchymal osteoblasts and surface osteoblasts. Eur Cell Mater 2008, 15:53-76.
2. Eyckmans J., Roberts S.J., Schrooten J., Luyten F.P. Aclinically relevant model of osteoinduction: a process requiring calcium phosphate and BMP/Wnt signalling. JCell Mol Med 2010, 14:1845-1856.
3. Detsch R., Mayr H., Ziegler G. Formation of osteoclast-like cells on HA and TCP ceramics. Acta Biomater 2008, 4:139-148.
4. Chai Y.C., Roberts S.J., Schrooten J., Luyten F.P. Probing the osteoinductive effect of calcium phosphate by using an invitro biomimetic model. Tissue Eng Part A 2011, 17:1083-1097.
5. Barrere F., van Blitterswijk C.A., de Groot K. Bone regeneration: molecular and cellular interactions with calcium phosphate ceramics. Int J Nanomedicine 2006, 1:317-332.
6. Riddle R.C., Khatri R., Schipani E., Clemens T.L. Role of hypoxia-inducible factor-1alpha in angiogenic-osteogenic coupling. JMol Med 2009, 87:583-590.
7. Laschke M.W., Harder Y., Amon M., Martin I., Farhadi J., Ring A., et al. Angiogenesis in tissue engineering: breathing life into constructed tissue substitutes. Tissue Eng 2006, 12:2093-2104.
8. Yuan H., Fernandes H., Habibovic P., de Boer J., Barradas A.M., de Ruiter A., et al. Osteoinductive ceramics as a synthetic alternative to autologous bone grafting. Proc Natl Acad Sci USA 2010, 107:13614-13619.
9. Chen J., Sotome S., Wang J., Orii H., Uemura T., Shinomiya K. Correlation of invivo bone formation capability and invitro differentiation of human bone marrow stromal cells. JMed Dent Sci 2005, 52:27-34.
10. Cheng L., Ye F., Yang R., Lu X., Shi Y., Li L., et al. Osteoinduction of hydroxyapatite/beta-tricalcium phosphate bioceramics in mice with a fractured fibula. Acta Biomater 2010, 6:1569-1574.
11. Habibovic P., Gbureck U., Doillon C.J., Bassett D.C., van Blitterswijk C.A., Barralet J.E. Osteoconduction and osteoinduction of low-temperature 3D printed bioceramic implants. Biomaterials 2008, 29:944-953.
12. Roberts S.J., Geris L., Kerckhofs G., Desmet E., Schrooten J., Luyten F.P. The combined bone forming capacity of human periosteal derived cells and calcium phosphates. Biomaterials 2011, 32(19):4393-4405.
13. Eyckmans J., Luyten F.P. Species specificity of ectopic bone formation using periosteum-derived mesenchymal progenitor cells. Tissue Eng 2006, 12:2203-2213.
14. Martin I., Mastrogiacomo M., De Leo G., Muraglia A., Beltrame F., Cancedda R., et al. Fluorescence microscopy imaging of bone for automated histomorphometry. Tissue Eng 2002, 8:847-852.
15. Verhaeghe J., Van Herck E., Van Bree R., Van Assche F.A., Bouillon R. Osteocalcin during the reproductive cycle in normal and diabetic rats. JEndocrinol 1989, 120:143-151.
16. Bouillon R., Vanderschueren D., Van Herck E., Nielsen H.K., Bex M., Heyns W., et al. Homologous radioimmunoassay of human osteocalcin. Clin Chem 1992, 38:2055-2060.
17. Rabau M.Y., Dayan D. Polarization microscopy of picrosirius red stained sections: a useful method for qualitative evaluation of intestinal wall collagen. Histol Histopathol 1994, 9:525-528.
18. Tullberg-Reinert H., Jundt G. In situ measurement of collagen synthesis by human bone cells with a sirius red-based colorimetric microassay: effects of transforming growth factor beta2 and ascorbic acid 2-phosphate. Histochem Cell Biol 1999, 112:271-276.
19. Sawyer A., Lott P., Titrud J., McDonald J. Quantification of tartrate resistant acid phosphatase distribution in mouse tibiae using image analysis. Biotech Histochem 2003, 78:271-278.
20. Janes K.A., Albeck J.G., Gaudet S., Sorger P.K., Lauffenburger D.A., Yaffe M.B. Asystems model of signaling identifies a molecular basis set for cytokine-induced apoptosis. Science 2005, 310:1646-1653.
21. Miller-Jensen K., Janes K.A., Brugge J.S., Lauffenburger D.A. Common effector processing mediates cell-specific responses to stimuli. Nature 2007, 448:604-608.
22. Platt M.O., Wilder C.L., Wells A., Griffith L.G., Lauffenburger D.A. Multipathway kinase signatures of multipotent stromal cells are predictive for osteogenic differentiation: tissue-specific stem cells. Stem Cells 2009, 27:2804-2814.
23. Janes K.A., Kelly J.R., Gaudet S., Albeck J.G., Sorger P.K., Lauffenburger D.A. Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data. JComput Biol 2004, 11:544-561.
24. Lu Z., Zreiqat H. The osteoconductivity of biomaterials is regulated by bone morphogenetic protein 2 autocrine loop involving alpha2beta1 integrin and mitogen-activated protein kinase/extracellular related kinase signaling pathways. Tissue Eng Part A 2010, 16:3075-3084.
25. Farrell E., Both S.K., Odorfer K.I., Koevoet W., Kops N., O'Brien F.J., et al. In-vivo generation of bone via endochondral ossification by in-vitro chondrogenic priming of adult human and rat mesenchymal stem cells. BMC Musculoskelet Disord 2011, 12:31.
26. Topol L., Jiang X., Choi H., Garrett-Beal L., Carolan P.J., Yang Y. Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation. JCell Biol 2003, 162:899-908.
27. 2+ signaling. Mech Dev 2001, 106:61-76.
28. Kruyt M.C., De Bruijn J., Veenhof M., Oner F.C., Van Blitterswijk C.A., Verbout A.J., et al. Application and limitations of chloromethyl-benzamidodialkylcarbocyanine fortracing cells used in bone tissue engineering. Tissue Eng 2003, 9:105-115.
29. Alves H., Munoz-Najar U., De Wit J., Renard A.J., Hoeijmakers J.H., Sedivy J.M., et al. Alink between the accumulation of DNA damage and loss of multi-potency of human mesenchymal stromal cells. JCell Mol Med 2010, 14:2729-2738.
30. De Bari C., Dell'Accio F., Karystinou A., Guillot P.V., Fisk N.M., Jones E.A., et al. Abiomarker-based mathematical model to predict bone-forming potency of human synovial and periosteal mesenchymal stem cells. Arthritis Rheum 2008, 58:240-250.
31. Fernandes H., Mentink A., Bank R., Stoop R., van Blitterswijk C., de Boer J. Endogenous collagen influences differentiation of human multipotent mesenchymal stromal cells. Tissue Eng Part A 2010, 16:1693-1702.
32. Mbalaviele G., Jaiswal N., Meng A., Cheng L., Van Den Bos C., Thiede M. Human mesenchymal stem cells promote human osteoclast differentiation from CD34+ bone marrow hematopoietic progenitors. Endocrinology 1999, 140:3736-3743.
33. Baron R., Rawadi G. Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton. Endocrinology 2007, 148:2635-2643.
34. Tang J., Xie Q., Pan G., Wang J., Wang M. Mesenchymal stem cells participate in angiogenesis and improve heart function in rat model of myocardial ischemia with reperfusion. Eur J Cardiothorac Surg 2006, 30:353-361.
35. Tortelli F., Tasso R., Loiacono F., Cancedda R. The development of tissue-engineered bone of different origin through endochondral and intramembranous ossification following the implantation of mesenchymal stem cells and osteoblasts in a murine model. Biomaterials 2010, 31:242-249.