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Volumn 145, Issue 1-2, 2012, Pages 179-190

Efficacy of QCDCR formulated CpG ODN 2007 in Nile tilapia against Streptococcus iniae and identification of upregulated genes

Author keywords

CpG oligodeoxynucleotide; Oreochromis niloticus; Streptococcus iniae; Subtractive hybridization; Upregulation

Indexed keywords

CARBOMER; CARBOXYPEPTIDASE; CHOLESTEROL; COMPLEMENTARY DNA; CPG OLIGODEOXYNUCLEOTIDE; DIMETHYL DIOCTADECYL AMMONIUM BROMIDE; GLUTAREDOXIN; QUIL A; R 1005 GLYCOLIPID; SARCOSINE OXIDASE; UNCLASSIFIED DRUG;

EID: 84856556622     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2011.11.001     Document Type: Article
Times cited : (17)

References (48)
  • 1
    • 34247120555 scopus 로고    scopus 로고
    • Streptococcus iniae: an aquatic pathogen of global veterinary significance and a challenging candidate for reliable vaccination
    • Agnew W., Barnes A.C. Streptococcus iniae: an aquatic pathogen of global veterinary significance and a challenging candidate for reliable vaccination. Vet. Microbiol. 2007, 122:1-15.
    • (2007) Vet. Microbiol. , vol.122 , pp. 1-15
    • Agnew, W.1    Barnes, A.C.2
  • 2
    • 0019783812 scopus 로고
    • Potency testing of fish vaccines
    • Amend D.F. Potency testing of fish vaccines. Dev. Biol. Stand. 1981, 49:447-454.
    • (1981) Dev. Biol. Stand. , vol.49 , pp. 447-454
    • Amend, D.F.1
  • 3
    • 0037963680 scopus 로고    scopus 로고
    • Immunostimulatory CpG oligodeoxynucleotides increase resistance against amoebic gill disease in Atlantic salmon, Salmo salar L
    • Bridle A.R., Butler R., Nowak B.F. Immunostimulatory CpG oligodeoxynucleotides increase resistance against amoebic gill disease in Atlantic salmon, Salmo salar L. J. Fish Dis. 2003, 26:367-371.
    • (2003) J. Fish Dis. , vol.26 , pp. 367-371
    • Bridle, A.R.1    Butler, R.2    Nowak, B.F.3
  • 4
    • 0033620673 scopus 로고    scopus 로고
    • Streptococcus iniae, a bacterial infection in barramundi Lates calcarifer
    • Bromage E.S., Thomas A., Owens L. Streptococcus iniae, a bacterial infection in barramundi Lates calcarifer. Dis. Aquat. Organ. 1999, 36:177-181.
    • (1999) Dis. Aquat. Organ. , vol.36 , pp. 177-181
    • Bromage, E.S.1    Thomas, A.2    Owens, L.3
  • 5
    • 34547597766 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides up-regulate antibacterial systems and induce protection against bacterial challenge in rainbow trout (Oncorhynchus mykiss)
    • Carrington A.C., Secombes C.J. CpG oligodeoxynucleotides up-regulate antibacterial systems and induce protection against bacterial challenge in rainbow trout (Oncorhynchus mykiss). Fish Shellfish Immunol. 2007, 23:781-792.
    • (2007) Fish Shellfish Immunol. , vol.23 , pp. 781-792
    • Carrington, A.C.1    Secombes, C.J.2
  • 6
    • 77649189039 scopus 로고    scopus 로고
    • Identification and immunoprotective analysis of a Streptococcus iniae subunit vaccine candidate
    • Cheng S., Hu Y.H., Jiao X.D., Sun L. Identification and immunoprotective analysis of a Streptococcus iniae subunit vaccine candidate. Vaccine 2010, 28:2636-2641.
    • (2010) Vaccine , vol.28 , pp. 2636-2641
    • Cheng, S.1    Hu, Y.H.2    Jiao, X.D.3    Sun, L.4
  • 7
    • 84954358591 scopus 로고    scopus 로고
    • Unmethylated CpG motifs mimicking bacterial DNA triggers the local and systemic innate immune parameters and expression of immune-relevant genes in gilthead seabream
    • Cuesta A., Salinas I., Esteban M.A., Meseguer J. Unmethylated CpG motifs mimicking bacterial DNA triggers the local and systemic innate immune parameters and expression of immune-relevant genes in gilthead seabream. Fish Shellfish Immunol. 2008, 25:617-624.
    • (2008) Fish Shellfish Immunol. , vol.25 , pp. 617-624
    • Cuesta, A.1    Salinas, I.2    Esteban, M.A.3    Meseguer, J.4
  • 8
    • 34249720524 scopus 로고    scopus 로고
    • Laboratory efficacy of florfenicol against Streptococcus iniae infection in sunshine bass
    • Darwish A.M. Laboratory efficacy of florfenicol against Streptococcus iniae infection in sunshine bass. J. Aquat. Anim. Health 2007, 19:1-7.
    • (2007) J. Aquat. Anim. Health , vol.19 , pp. 1-7
    • Darwish, A.M.1
  • 9
    • 0027366974 scopus 로고
    • Substrate specificity of the Escherichia coli endonuclease III: excision of thymine- and cytosine-derived lesions in DNA produced by radiation-generated free radicals
    • Dizdaroglu M., Laval J., Boiteux S. Substrate specificity of the Escherichia coli endonuclease III: excision of thymine- and cytosine-derived lesions in DNA produced by radiation-generated free radicals. Biochemistry 1993, 32:12105-12111.
    • (1993) Biochemistry , vol.32 , pp. 12105-12111
    • Dizdaroglu, M.1    Laval, J.2    Boiteux, S.3
  • 10
    • 0033549150 scopus 로고    scopus 로고
    • Red drum Sciaenops ocellatus mortalities associated with Streptococcus iniae infection
    • Eldar A., Perl S., Frelier P.F., Bercovier H. Red drum Sciaenops ocellatus mortalities associated with Streptococcus iniae infection. Dis. Aquat. Organ. 1999, 36:121-127.
    • (1999) Dis. Aquat. Organ. , vol.36 , pp. 121-127
    • Eldar, A.1    Perl, S.2    Frelier, P.F.3    Bercovier, H.4
  • 11
    • 55949120560 scopus 로고    scopus 로고
    • Emergence of novel Streptococcus iniae exopolysaccharide-producing strains following vaccination with nonproducing strains
    • Eyngor M., Tekoah Y., Shapira R., Hurvitz A., Zlotkin A., Lublin A., Eldar A. Emergence of novel Streptococcus iniae exopolysaccharide-producing strains following vaccination with nonproducing strains. Appl. Environ. Microbiol. 2008, 74:6892-6897.
    • (2008) Appl. Environ. Microbiol. , vol.74 , pp. 6892-6897
    • Eyngor, M.1    Tekoah, Y.2    Shapira, R.3    Hurvitz, A.4    Zlotkin, A.5    Lublin, A.6    Eldar, A.7
  • 13
    • 0028305721 scopus 로고
    • New substrates for old enzymes: 5-hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase
    • Hatahet Z., Kow Y.W., Purmal A.A., Cunningham R.P., Wallace S.S. New substrates for old enzymes: 5-hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase. J. Biol. Chem. 1994, 269:18814-18820.
    • (1994) J. Biol. Chem. , vol.269 , pp. 18814-18820
    • Hatahet, Z.1    Kow, Y.W.2    Purmal, A.A.3    Cunningham, R.P.4    Wallace, S.S.5
  • 14
    • 0032418283 scopus 로고    scopus 로고
    • Induction of c-fos, and cytochrome c oxidase subunits I and II by gossypol acetic acid in rat liver cells
    • Hutchinson R.W., Ing N.H., Burghardt R.C. Induction of c-fos, and cytochrome c oxidase subunits I and II by gossypol acetic acid in rat liver cells. Cell Biol. Toxicol. 1998, 14:391-399.
    • (1998) Cell Biol. Toxicol. , vol.14 , pp. 391-399
    • Hutchinson, R.W.1    Ing, N.H.2    Burghardt, R.C.3
  • 16
    • 0037159625 scopus 로고    scopus 로고
    • CpG-containing oligodeoxynucleotides, in combination with conventional adjuvants, enhance the magnitude and change the bias of the immune responses to a herpesvirus glycoprotein
    • Ioannou X.P., Gomis S.M., Karvonen B., Hecker R., Babiuk L.A., Van Drunen Littel-Van Den Hurk S. CpG-containing oligodeoxynucleotides, in combination with conventional adjuvants, enhance the magnitude and change the bias of the immune responses to a herpesvirus glycoprotein. Vaccine 2002, 21:127-137.
    • (2002) Vaccine , vol.21 , pp. 127-137
    • Ioannou, X.P.1    Gomis, S.M.2    Karvonen, B.3    Hecker, R.4    Babiuk, L.A.5    Van Drunen Littel-Van Den Hurk, S.6
  • 17
    • 0142028886 scopus 로고    scopus 로고
    • CpG DNA induces protective antiviral immune responses in Atlantic salmon (Salmo salar L.)
    • Jørgensen J.B., Johansen L.H., Steiro K., Johansen A. CpG DNA induces protective antiviral immune responses in Atlantic salmon (Salmo salar L.). J. Virol. 2003, 77:11471-11479.
    • (2003) J. Virol. , vol.77 , pp. 11471-11479
    • Jørgensen, J.B.1    Johansen, L.H.2    Steiro, K.3    Johansen, A.4
  • 18
    • 0034670155 scopus 로고    scopus 로고
    • Alterations in mitochondria and mtTFA in response to LPS-induced differentiation of B-cells
    • Kain K.H., Popov V.L., Herzog N.K. Alterations in mitochondria and mtTFA in response to LPS-induced differentiation of B-cells. Biochim. Biophys. Acta 2000, 1494:91-103.
    • (2000) Biochim. Biophys. Acta , vol.1494 , pp. 91-103
    • Kain, K.H.1    Popov, V.L.2    Herzog, N.K.3
  • 19
    • 4444291410 scopus 로고    scopus 로고
    • Streptococcus iniae discitis in Singapore
    • Koh T.H., Kurup A., Chen J. Streptococcus iniae discitis in Singapore. Emerg. Infect. Dis. 2004, 10:1694-1696.
    • (2004) Emerg. Infect. Dis. , vol.10 , pp. 1694-1696
    • Koh, T.H.1    Kurup, A.2    Chen, J.3
  • 20
    • 0034623661 scopus 로고    scopus 로고
    • Immune effects and mechanisms of action of CpG motifs
    • Krieg A.M. Immune effects and mechanisms of action of CpG motifs. Vaccine 2000, 19:618-622.
    • (2000) Vaccine , vol.19 , pp. 618-622
    • Krieg, A.M.1
  • 21
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg A.M. CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol. 2002, 20:709-760.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 709-760
    • Krieg, A.M.1
  • 22
    • 0141538058 scopus 로고    scopus 로고
    • CpG motif in synthetic ODN primes respiratory burst of olive flounder Paralichthys olivaceus phagocytes and enhances protection against Edwardsiella tarda
    • Lee C.H., Jeong H.D., Chung J.K., Lee H.H., Kim K.H. CpG motif in synthetic ODN primes respiratory burst of olive flounder Paralichthys olivaceus phagocytes and enhances protection against Edwardsiella tarda. Dis. Aquat. Organ. 2003, 56:43-48.
    • (2003) Dis. Aquat. Organ. , vol.56 , pp. 43-48
    • Lee, C.H.1    Jeong, H.D.2    Chung, J.K.3    Lee, H.H.4    Kim, K.H.5
  • 23
    • 78349311108 scopus 로고    scopus 로고
    • Embryo vaccination of chickens using a novel adjuvant formulation stimulates protective immunity against Eimeria maxima infection
    • Lee S.H., Lillehoj H.S., Jang S.I., Hong Y.H., Min W., Lillehoj E.P., Yancey R.J., Dominowski P. Embryo vaccination of chickens using a novel adjuvant formulation stimulates protective immunity against Eimeria maxima infection. Vaccine 2010, 28:7774-7778.
    • (2010) Vaccine , vol.28 , pp. 7774-7778
    • Lee, S.H.1    Lillehoj, H.S.2    Jang, S.I.3    Hong, Y.H.4    Min, W.5    Lillehoj, E.P.6    Yancey, R.J.7    Dominowski, P.8
  • 24
    • 2442559189 scopus 로고    scopus 로고
    • Dietary oligonucleotides from yeast RNA influence immune responses and resistance of hybrid striped bass (Morone chrysops×Morone saxatilis) to Streptococcus iniae infection
    • Li P., Lewis D.H., Gatlin D.M. Dietary oligonucleotides from yeast RNA influence immune responses and resistance of hybrid striped bass (Morone chrysops×Morone saxatilis) to Streptococcus iniae infection. Fish Shellfish Immunol. 2004, 16:561-569.
    • (2004) Fish Shellfish Immunol. , vol.16 , pp. 561-569
    • Li, P.1    Lewis, D.H.2    Gatlin, D.M.3
  • 25
    • 65549103880 scopus 로고    scopus 로고
    • Pneumocystis mediates overexpression of antizyme inhibitor resulting in increased polyamine levels and apoptosis in alveolar macrophages
    • Liao C.P., Lasbury M.E., Wang S.H., Zhang C., Durant P.J., Murakami Y., Matsufuji S., Lee C.H. Pneumocystis mediates overexpression of antizyme inhibitor resulting in increased polyamine levels and apoptosis in alveolar macrophages. J. Biol. Chem. 2009, 284:8174-8184.
    • (2009) J. Biol. Chem. , vol.284 , pp. 8174-8184
    • Liao, C.P.1    Lasbury, M.E.2    Wang, S.H.3    Zhang, C.4    Durant, P.J.5    Murakami, Y.6    Matsufuji, S.7    Lee, C.H.8
  • 26
    • 77954955360 scopus 로고    scopus 로고
    • Identification and analysis of the immune effects of CpG motifs that protect Japanese flounder (Paralichthys olivaceus) against bacterial infection
    • Liu C.S., Sun Y., Hu Y.H., Sun L. Identification and analysis of the immune effects of CpG motifs that protect Japanese flounder (Paralichthys olivaceus) against bacterial infection. Fish Shellfish Immunol. 2010, 29:279-325.
    • (2010) Fish Shellfish Immunol. , vol.29 , pp. 279-325
    • Liu, C.S.1    Sun, Y.2    Hu, Y.H.3    Sun, L.4
  • 27
    • 77952582934 scopus 로고    scopus 로고
    • Identification and analysis of a CpG motif that protects turbot (Scophthalmus maximus) against bacterial challenge and enhances vaccine-induced specific immunity
    • Liu C.S., Sun Y., Hu Y.H., Sun L. Identification and analysis of a CpG motif that protects turbot (Scophthalmus maximus) against bacterial challenge and enhances vaccine-induced specific immunity. Vaccine 2010, 28:4153-4161.
    • (2010) Vaccine , vol.28 , pp. 4153-4161
    • Liu, C.S.1    Sun, Y.2    Hu, Y.H.3    Sun, L.4
  • 28
    • 77952311683 scopus 로고    scopus 로고
    • Evaluation of Streptococcus iniae killed bacterin and live attenuated vaccines in hybrid striped bass through injection and bath immersion
    • Locke J.B., Vicknair M.R., Ostland V.E., Nizet V., Buchanan J.T. Evaluation of Streptococcus iniae killed bacterin and live attenuated vaccines in hybrid striped bass through injection and bath immersion. Dis. Aquat. Organ. 2010, 89:117-123.
    • (2010) Dis. Aquat. Organ. , vol.89 , pp. 117-123
    • Locke, J.B.1    Vicknair, M.R.2    Ostland, V.E.3    Nizet, V.4    Buchanan, J.T.5
  • 29
    • 0346849668 scopus 로고    scopus 로고
    • Carboxypeptidase N: a pleiotropic regulator of inflammation
    • Mathews K., Mueller-Ortiz S., Wetsel R. Carboxypeptidase N: a pleiotropic regulator of inflammation. Mol. Immunol. 2004, 40:785-793.
    • (2004) Mol. Immunol. , vol.40 , pp. 785-793
    • Mathews, K.1    Mueller-Ortiz, S.2    Wetsel, R.3
  • 30
    • 39149138715 scopus 로고    scopus 로고
    • Overexpression of glutaredoxin-2 reduces myocardial cell death by preventing both apoptosis and necrosis
    • Nagy N., Malik G., Tosaki A., Ho Y.S., Maulik N., Das D.K. Overexpression of glutaredoxin-2 reduces myocardial cell death by preventing both apoptosis and necrosis. J. Mol. Cell. Cardiol. 2008, 44:252-260.
    • (2008) J. Mol. Cell. Cardiol. , vol.44 , pp. 252-260
    • Nagy, N.1    Malik, G.2    Tosaki, A.3    Ho, Y.S.4    Maulik, N.5    Das, D.K.6
  • 31
    • 4544267616 scopus 로고    scopus 로고
    • Transcriptome analysis and gene expression profiles of early apoptosis-related genes in Streptococcus pyogenes-infected epithelial cells
    • Nakagawa I., Nakata M., Kawabata S., Hamada S. Transcriptome analysis and gene expression profiles of early apoptosis-related genes in Streptococcus pyogenes-infected epithelial cells. Cell. Microbiol. 2004, 6:939-952.
    • (2004) Cell. Microbiol. , vol.6 , pp. 939-952
    • Nakagawa, I.1    Nakata, M.2    Kawabata, S.3    Hamada, S.4
  • 32
    • 0017125616 scopus 로고
    • Streptococcus iniae sp. nov., a beta-hemolytic Streptococcus isolated from an Amazon freshwater dolphin Inia geoffrensis
    • Pier G.B., Madin S.H. Streptococcus iniae sp. nov., a beta-hemolytic Streptococcus isolated from an Amazon freshwater dolphin Inia geoffrensis. Int. J. Syst. Bacteriol. 1976, 26:545-553.
    • (1976) Int. J. Syst. Bacteriol. , vol.26 , pp. 545-553
    • Pier, G.B.1    Madin, S.H.2
  • 33
    • 79960068436 scopus 로고    scopus 로고
    • Identification and expression profile of multiple genes in Nile tilapia in response to formalin killed Streptococcus iniae vaccination
    • Pridgeon J.W., Klesius P.H. Identification and expression profile of multiple genes in Nile tilapia in response to formalin killed Streptococcus iniae vaccination. Vet. Immunol. Immunopathol. 2011, 142:201-206.
    • (2011) Vet. Immunol. Immunopathol. , vol.142 , pp. 201-206
    • Pridgeon, J.W.1    Klesius, P.H.2
  • 34
    • 79960745415 scopus 로고    scopus 로고
    • Development and efficacy of a novobiocin-resistant Streptococcus iniae as a novel vaccine in Nile tilapia (Oreochromis niloticus)
    • Pridgeon J.W., Klesius P.H. Development and efficacy of a novobiocin-resistant Streptococcus iniae as a novel vaccine in Nile tilapia (Oreochromis niloticus). Vaccine 2011, 29:5986-5993.
    • (2011) Vaccine , vol.29 , pp. 5986-5993
    • Pridgeon, J.W.1    Klesius, P.H.2
  • 35
    • 77349113768 scopus 로고    scopus 로고
    • Identification and expression profile of multiple genes in the anterior kidney of channel catfish induced by modified live Edwardsiella ictaluri vaccination
    • Pridgeon J.W., Shoemaker C.A., Klesius P.H. Identification and expression profile of multiple genes in the anterior kidney of channel catfish induced by modified live Edwardsiella ictaluri vaccination. Vet. Immunol. Immunopathol. 2010, 134:184-198.
    • (2010) Vet. Immunol. Immunopathol. , vol.134 , pp. 184-198
    • Pridgeon, J.W.1    Shoemaker, C.A.2    Klesius, P.H.3
  • 36
    • 0030996664 scopus 로고    scopus 로고
    • Cloning and functional expression of a mammalian gene for a peroxisomal sarcosine oxidase
    • Reuber B.E., Karl C., Reimann S.A., Mihalik S.J., Dodt G. Cloning and functional expression of a mammalian gene for a peroxisomal sarcosine oxidase. J. Biol. Chem. 1997, 272:6766-6776.
    • (1997) J. Biol. Chem. , vol.272 , pp. 6766-6776
    • Reuber, B.E.1    Karl, C.2    Reimann, S.A.3    Mihalik, S.J.4    Dodt, G.5
  • 37
    • 0034667770 scopus 로고    scopus 로고
    • Phosphorothioate backbone modification modulates macrophage activation by CpG DNA
    • Sester D.P., Naik S., Beasley S.J., Hume D.A., Stacey K.J. Phosphorothioate backbone modification modulates macrophage activation by CpG DNA. J. Immunol. 2000, 165:4165e73.
    • (2000) J. Immunol. , vol.165
    • Sester, D.P.1    Naik, S.2    Beasley, S.J.3    Hume, D.A.4    Stacey, K.J.5
  • 38
    • 77954730917 scopus 로고    scopus 로고
    • Protection against heterologous Streptococcus iniae isolates using a modified bacterin vaccine in Nile tilapia Oreochromis niloticus (L.)
    • Shoemaker C.A., Lafrentz B.R., Klesius P.H., Evans J.J. Protection against heterologous Streptococcus iniae isolates using a modified bacterin vaccine in Nile tilapia Oreochromis niloticus (L.). J. Fish Dis. 2010, 33:537-544.
    • (2010) J. Fish Dis. , vol.33 , pp. 537-544
    • Shoemaker, C.A.1    Lafrentz, B.R.2    Klesius, P.H.3    Evans, J.J.4
  • 40
    • 77952422865 scopus 로고    scopus 로고
    • Construction and analysis of an experimental Streptococcus iniae DNA vaccine
    • Sun Y., Hu Y.H., Liu C.S., Sun L. Construction and analysis of an experimental Streptococcus iniae DNA vaccine. Vaccine 2010, 28:3905-3912.
    • (2010) Vaccine , vol.28 , pp. 3905-3912
    • Sun, Y.1    Hu, Y.H.2    Liu, C.S.3    Sun, L.4
  • 42
    • 0029119097 scopus 로고
    • Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure
    • Thayer M.M., Ahern H., Xing D., Cunningham R.P., Tainer J.A. Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure. EMBO J. 1995, 14:4108-4120.
    • (1995) EMBO J. , vol.14 , pp. 4108-4120
    • Thayer, M.M.1    Ahern, H.2    Xing, D.3    Cunningham, R.P.4    Tainer, J.A.5
  • 43
    • 61849161673 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotide-based therapy of lymphoid malignancies
    • Weiner G.J. CpG oligodeoxynucleotide-based therapy of lymphoid malignancies. Adv. Drug Deliv. Rev. 2009, 61:263-267.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 263-267
    • Weiner, G.J.1
  • 46
    • 33746848109 scopus 로고    scopus 로고
    • A rapid and sensitive assay for the quantitation of carboxypeptidase N, an important regulator of inflammation
    • Willemse J.L., Hendriks D.F. A rapid and sensitive assay for the quantitation of carboxypeptidase N, an important regulator of inflammation. Clin. Chim. Acta 2006, 371:124-129.
    • (2006) Clin. Chim. Acta , vol.371 , pp. 124-129
    • Willemse, J.L.1    Hendriks, D.F.2
  • 47
    • 77958610739 scopus 로고    scopus 로고
    • Ornithine decarboxylase antizyme induces hypomethylation of genome DNA and histone H3 lysine 9 dimethylation (H3K9me2) in human oral cancer cell line
    • Yamamoto D., Shima K., Matsuo K., Nishioka T., Chen C.Y., Hu G.F., Sasaki A., Tsuji T. Ornithine decarboxylase antizyme induces hypomethylation of genome DNA and histone H3 lysine 9 dimethylation (H3K9me2) in human oral cancer cell line. PLoS ONE 2010, 5:e12554.
    • (2010) PLoS ONE , vol.5
    • Yamamoto, D.1    Shima, K.2    Matsuo, K.3    Nishioka, T.4    Chen, C.Y.5    Hu, G.F.6    Sasaki, A.7    Tsuji, T.8
  • 48
    • 78650518130 scopus 로고    scopus 로고
    • MtsB, a hydrophobic membrane protein of Streptococcus iniae, is an effective subunit vaccine candidate
    • Zou L., Wang J., Huang B., Xie M., Li A. MtsB, a hydrophobic membrane protein of Streptococcus iniae, is an effective subunit vaccine candidate. Vaccine 2011, 29:391-394.
    • (2011) Vaccine , vol.29 , pp. 391-394
    • Zou, L.1    Wang, J.2    Huang, B.3    Xie, M.4    Li, A.5


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