Loss of UDP-N-acetylglucosamine 2-epimerase/ N-acetylmannosamine kinase (GNE) induces apoptotic processes in pancreatic carcinoma cells

FASEB Journal

Volumn 26, Issue 2, 2012, Pages 938-946

  Kemmner, Wolfgang ^a   Kessel, Pia ^a   Sanchez Ruderisch, Hugo ^a   Möller, Heinz ^b   Hinderlich, Stephan ^b   Schlag, Peter M ^a   Detjen, Katharina ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b BEUTH UNIVERSITY OF APPLIED SCIENCES   (Germany)

Author keywords

Anoikis; Chemoresistance; Sialylation; Unfolded protein response

Indexed keywords

N ACETYLMANNOSAMINE KINASE; PHOSPHOTRANSFERASE; PROTEIN P16; SIALIC ACID; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE 2 EPIMERASE;

ANOIKIS; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SYNTHESIS; GENE EXPRESSION PROFILING; GENE SILENCING; HUMAN; HUMAN CELL; PANCREAS CARCINOMA; PRIORITY JOURNAL; TRANSCRIPTION INITIATION; UPREGULATION; WESTERN BLOTTING;

ANOIKIS; APOPTOSIS; BASE SEQUENCE; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM STRESS; GENE KNOCKDOWN TECHNIQUES; GENES, P16; HUMANS; INTEGRIN ALPHA5BETA1; MULTIENZYME COMPLEXES; PANCREATIC NEOPLASMS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIALIC ACIDS; UP-REGULATION;

EID: 84856551140     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-186700     Document Type: Article

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