Nitric oxide potentiates TNF-α-induced neurotoxicity through suppression of NF-κB

Cellular and Molecular Neurobiology

Volumn 32, Issue 1, 2012, Pages 95-106

  Nakaizumi, Atsuko ^a   Horie, Taeko ^a   Kida, Teruyo ^a   Kurimoto, Takuji ^a   Sugiyama, Tetsuya ^a   Ikeda, Tsunehiko ^a   Oku, Hidehiro ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Neurotoxicity; Nitric oxide; Nitrosylation; Nuclear factor B; TNF

Indexed keywords

AMINOGUANIDINE; ETANERCEPT; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; N(G) NITROARGININE METHYL ESTER; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLSERINE; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; FLOW CYTOMETRY; LONG TERM EXPOSURE; MOUSE; NERVE CELL NECROSIS; NEUROTOXICITY; NITROSYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETINA GANGLION CELL; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN; CELL DEATH; CELLS, CULTURED; DOWN-REGULATION; DRUG SYNERGISM; MICE; NEURONS; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; NITROSATION; S-NITROSO-N-ACETYLPENICILLAMINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84856535017     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-011-9739-5     Document Type: Article

References (52)

1. Bae SR, Wu GS, Sevanian A, Schultz BE, Zamir E, Rao NA (2007) Direct detection of reactive nitrogen species in experimental autoimmune uveitis. Korean J Ophthalmol 21:21-27
2. Beg AA, Baltimore D (1996) An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 274:782-784 (Pubitemid 26398258)
3. Behl Y, Krothapalli P, Desta T, DiPiazza A, Roy S, Graves DT (2008) Diabetes-enhanced tumor necrosis factor-alpha production promotes apoptosis and the loss of retinal microvascular cells in type 1 and type 2 models of diabetic retinopathy. Am J Pathol 172: 1411-1418 (Pubitemid 351671553)
4. Benveniste EN, Benos DJ (1995) TNF-alpha-and IFN-gammamediated signal transduction pathways: Effects on glial cell gene expression and function. FASEB J. 9:1577-1584
5. Berger S, Savitz SI, Nijhawan S, Singh M, David J, Rosenbaum PS, Rosenbaum DM (2008) Deleterious role of TNF-alpha in retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci 49: 3605-3610
6. Brown GC, Cooper CE (1994) Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase. FEBS Lett 356:295-298 (Pubitemid 24376992)
7. Cai J, Jiang WG, Ahmed A, Boulton M (2006) Vascular endothelial growth factor-induced endothelial cell proliferation is regulated by interaction between VEGFR-2, SH-PTP1 and eNOS. Microvasc Res 71:20-31 (Pubitemid 43175845)
8. Colasanti M, Persichini T (2000) Nitric oxide: An inhibitor of NFkappaB/ Rel system in glial cells. Brain Res Bull 52:155-161 (Pubitemid 30261504)
9. Colasanti M, Persichini T, Menegazzi M, Mariotto S, Giordano E, Caldarera CM, Sogos V, Lauro GM, Suzuki H (1995) Induction of nitric oxide synthase mRNA expression. Suppression by exogenous nitric oxide. J Biol Chem 270:26731-26733
10. Figiel I (2008) Pro-inflammatory cytokine TNF-alpha as a neuroprotective agent in the brain. Acta Neurobiol Exp (Wars) 68: 526-534
11. Frassetto LJ, Schlieve CR, Lieven CJ, Utter AA, Jones MV, Agarwal N, Levin LA (2006) Kinase-dependent differentiation of a retinal ganglion cell precursor. Invest Ophthalmol Vis Sci 47:427-438 (Pubitemid 46780844)
12. Fuchs C, Forster V, Balse E, Sahel JA, Picaud S, Tessier LH (2005) Retinal-cell-conditioned medium prevents TNF-alpha-induced apoptosis of purified ganglion cells. Invest Ophthalmol Vis Sci 46: 2983-2991 (Pubitemid 43086723)
13. Furuno T, Nakanishi M (2006) Neurotrophic factors increase tumor necrosis factor-alpha-induced nuclear translocation of NF-kappaB in rat PC12 cells. Neurosci Lett 392:240-244 (Pubitemid 41739633)
14. Galea E, Feinstein DL, Reis DJ (1992) Induction of calciumindependent nitric oxide synthase activity in primary rat glial cultures. Proc Natl Acad Sci USA 89:10945-10949
15. Gruss HJ, Dower SK (1995) The TNF ligand superfamily and its relevance for human diseases. Cytokines Mol Ther 1:75-105
16. Haberecht MF, Schmidt HH, Mills SL, Massey SC, Nakane M, Redburn-Johnson DA (1998) Localization of nitric oxide synthase, NADPH diaphorase and soluble guanylyl cyclase in adult rabbit retina. Vis Neurosci 15:881-890 (Pubitemid 28436941)
17. Heneka MT, Loschmann PA, Gleichmann M, Weller M, Schulz JB, Wullner U, Klockgether T (1998) Induction of nitric oxide synthase and nitric oxide-mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-alpha/lipopolysaccharide. J Neurochem 71:88-94 (Pubitemid 28292538)
18. Heyninck K, Beyaert R (2001) Crosstalk between NF-kappaBactivating and apoptosis-inducing proteins of the TNF-receptor complex. Mol Cell Biol Res Commun 4:259-265 (Pubitemid 32879079)
19. Hsu H, Xiong J, Goeddel DV (1995) The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation. Cell 81:495-504
20. Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G (1987) Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci USA 84: 9265-9269
21. Jaffrey SR, Snyder SH (2001) The biotin switch method for the detection of S-nitrosylated proteins. Sci STKE 86:l1
22. Joussen AM, Doehmen S, Le ML, Koizumi K, Radetzky S, Krohne TU, Poulaki V, Semkova I, Kociok N (2009) TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations. Mol Vis 15:1418-1428
23. Kiel JW (1999) Modulation of choroidal autoregulation in the rabbit. Exp Eye Res 69:413-429 (Pubitemid 29469909)
24. Koch KW, Lambrecht HG, Haberecht M, Redburn D, Schmidt HH (1994) Functional coupling of a Ca2+/calmodulin-dependent nitric oxide synthase and a soluble guanylyl cyclase in vertebrate photoreceptor cells. EMBO J 13:3312-3320
25. Koizumi K, Poulaki V, Doehmen S, Welsandt G, Radetzky S, Lappas A, Kociok N, Kirchhof B, Joussen AM (2003) Contribution of TNF-alpha to leukocyte adhesion, vascular leakage, and apoptotic cell death in endotoxin-induced uveitis in vivo. Invest Ophthalmol Vis Sci 44:2184-2191 (Pubitemid 36520316)
26. Krishnamoorthy RR, Agarwal P, Prasanna G, Vopat K, Lambert W, Sheedlo HJ, Pang IH, Shade D, Wordinger RJ, Yorio T, Clark AF, Agarwal N (2001) Characterization of a transformed rat retinal ganglion cell line. Brain Res Mol Brain Res 86:1-12 (Pubitemid 32124753)
27. Landar A, Darley-Usmar VM (2003) Nitric oxide and cell signaling: Modulation of redox tone and protein modification. Amino Acids 25:313-321 (Pubitemid 38041268)
28. Liversidge J, Dick A, Gordon S (2002) Nitric oxide mediates apoptosis through formation of peroxynitrite and Fas/Fas-ligand interactions in experimental autoimmune uveitis. Am J Pathol 160:905-916 (Pubitemid 34224580)
29. Manabe S, Gu Z, Lipton SA (2005) Activation of matrix metalloproteinase-9 via neuronal nitric oxide synthase contributes to NMDA-induced retinal ganglion cell death. Invest Ophthalmol Vis Sci 46:4747-4753 (Pubitemid 44264580)
30. Marshall HE, Stamler JS (2001) Inhibition of NF-kappa B by Snitrosylation. Biochemistry 40:1688-1693
31. Marshall HE, Hess DT, Stamler JS (2004) S-nitrosylation: Physiological regulation of NF-kappaB. Proc Natl Acad Sci USA. 101:8841-8842
32. Mitomo K, Nakayama K, Fujimoto K, Sun X, Seki S, Yamamoto K (1994) Two different cellular redox systems regulate the DNAbinding activity of the p50 subunit of NF-kappa B in vitro. Gene 145:197-203 (Pubitemid 24261434)
33. Miura-Takeda S, Tashiro-Yamaji J, Oku H, Takahashi T, Shimizu T, Sugiyama T, Ikeda T, Kubota T, Yoshida R (2008) Experimental autoimmune uveoretinitis initiated by non-phagocytic destruction of inner segments of photoreceptor cells by Mac-1(?) mononuclear cells. Microbiol Immunol 52:601-610
34. Neufeld AH (1999) Nitric oxide: A potential mediator of retinal ganglion cell damage in glaucoma. Surv Ophthalmol 43:S129-S135 (Pubitemid 29328587)
35. Neufeld AH, Shareef S, Pena J (2000) Cellular localization of neuronal nitric oxide synthase (NOS-1) in the human and rat retina. J Comp Neurol 416:269-275
36. Osborne NN (2008) Pathogenesis of ganglion "cell death" in glaucoma and neuroprotection: Focus on ganglion cell axonal mitochondria. Prog Brain Res 173:339-352
37. Park A, Baichwal VR (1996) Systematic mutational analysis of the death domain of the tumor necrosis factor receptor 1-associated protein TRADD. J Biol Chem 271:9858-9862 (Pubitemid 26137401)
38. Raivich G, Bohatschek M, Kloss CU, Werner A, Jones LL, Kreutzberg GW (1999) Neuroglial activation repertoire in the injured brain: Graded response, molecular mechanisms and cues to physiological function. Brain Res Brain Res Rev 30:77-105 (Pubitemid 29331517)
39. Rajendram R, Saraswathy S, Rao NA (2007) Photoreceptor mitochondrial oxidative stress in early experimental autoimmune uveoretinitis. Br J Ophthalmol 91:531-537 (Pubitemid 46623691)
40. Sato T, Oku H, Tsuruma K, Katsumura K, Shimazawa M, Hara H, Sugiyama T, Ikeda T (2010) Effect of hypoxia on susceptibility of RGC-5 cells to nitric oxide. Invest Ophthalmol Vis Sci 51:2575-2586
41. Smith CA, Farrah T, Goodwin RG (1994) The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death. Cell 76:959-962 (Pubitemid 24106376)
42. Tezel G (2008) TNF-alpha signaling in glaucomatous neurodegeneration. Prog Brain Res 173:409-421
43. Tezel G, Wax MB (2000) Increased production of tumor necrosis factor-alpha by glial cells exposed to simulated ischemia or elevated hydrostatic pressure induces apoptosis in cocultured retinal ganglion cells. J Neurosci 20:8693-8700
44. Togashi H, Sasaki M, Frohman E, Taira E, Ratan RR, Dawson TM, Dawson VL (1997) Neuronal (type I) nitric oxide synthase regulates nuclear factor kappaB activity and immunologic (type II) nitric oxide synthase expression. Proc Natl Acad Sci USA 94:2676-2680
45. Uehara T, Nakamura T, Yao D, Shi ZQ, Gu Z, Ma Y, Masliah E, Nomura Y, Lipton SA (2006) S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration. Nature 441:513-517 (Pubitemid 44050153)
46. Van Antwerp DJ, Martin SJ, Kafri T, Green DR, Verma IM (1996) Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science 274:787-789
47. Van Bergen NJ, Wood JP, Chidlow G, Trounce IA, Casson RJ, Ju WK, Weinreb RN, Crowston JG (2009) Recharacterization of the RGC-5 retinal ganglion cell line. Invest Ophthalmol Vis Sci 50:4267-4272
48. Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr (1998) NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281:1680-1683
49. Wolff DJ, Gauld DS, Neulander MJ, Southan G (1997) Inactivation of nitric oxide synthase by substituted aminoguanidines and aminoisothioureas. J Pharmacol Exp Ther 283:265-273 (Pubitemid 27438970)
50. Wood JP, Chidlow G, Tran T, Crowston JG, Casson RJ (2010) A comparison of differentiation protocols for RGC-5 cells. Invest Ophthalmol Vis Sci 51:3774-3783
51. Yang LP, Zhu XA, Tso MO (2007) A possible mechanism of microglia-photoreceptor crosstalk. Mol Vis 13:2048-2057 (Pubitemid 350031852)
52. Zhang F, Qian L, Flood PM, Shi JS, Hong JS, Gao HM (2010) Inhibition of IkappaB kinase-beta protects dopamine neurons against lipopolysaccharide-induced neurotoxicity. J Pharmacol Exp Ther 333:822-833