High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality

Journal of Thrombosis and Haemostasis

Volumn 10, Issue 2, 2012, Pages 207-216

  Johansson, P I ^a   Sorensen A M ^a   Perner, A ^a   Welling, K L ^a   Wanscher, M ^a   Larsen, C F ^a   Ostrowski, S R ^a  

^a Mental Health Services CPH   (Denmark)

Author keywords

Coagulopathy; Endothelial glycocalyx; Platelets; SCD40L; Sympathoadrenal activation; Trauma

Indexed keywords

ADRENALIN; ANTITHROMBIN; BIOLOGICAL MARKER; BLOOD CLOTTING FACTOR 13; CD40 LIGAND; COMPLEMENT COMPONENT C5B; D DIMER; DNA FRAGMENT; FIBRINOGEN; HISTONE; INTERLEUKIN 6; LACTIC ACID; LIPOCORTIN 5; NORADRENALIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN C; SYNDECAN 1; THROMBOMODULIN; TISSUE FACTOR PATHWAY INHIBITOR; TISSUE PLASMINOGEN ACTIVATOR; VON WILLEBRAND FACTOR;

ADRENERGIC SYSTEM; ADULT; ARTICLE; BLOOD CLOTTING DISORDER; BLOOD SAMPLING; CONTROLLED STUDY; DEMOGRAPHY; DISEASE ASSOCIATION; ENDOTHELIUM INJURY; FEMALE; FIBRINOLYSIS; GLASGOW COMA SCALE; GLYCOCALYX; HOSPITAL ADMISSION; HUMAN; INFLAMMATION; INJURY SCALE; INTERNATIONAL NORMALIZED RATIO; MAJOR CLINICAL STUDY; MALE; MORTALITY; OBSERVATIONAL STUDY; PARTIAL THROMBOPLASTIN TIME; PH; PRIORITY JOURNAL; PROSPECTIVE STUDY; SHOCK; THROMBOCYTE COUNT; TISSUE INJURY;

ADRENAL GLANDS; ADULT; BIOLOGICAL MARKERS; BLOOD COAGULATION; CD40 LIGAND; CHI-SQUARE DISTRIBUTION; DENMARK; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; INJURY SEVERITY SCORE; LINEAR MODELS; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PROGNOSIS; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SHOCK; SYMPATHETIC NERVOUS SYSTEM; TIME FACTORS; TRAUMA CENTERS; UP-REGULATION; WOUNDS AND INJURIES;

EID: 84856514364     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2011.04589.x     Document Type: Article

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