Major furocoumarins in grapefruit juice II: Phototoxicity, photogenotoxicity, and inhibitory potency vs. cytochrome P450 3A4 activity

Food and Chemical Toxicology

Volumn 50, Issue 3-4, 2012, Pages 756-760

  Messer, Anastasia ^a   Raquet, Nicole ^a   Lohr, Christiane ^a   Schrenk, Dieter ^a  

^a Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

Author keywords

Bergamottin; Furocoumarins; Grapefruit juice; Photogenotoxic; Photomutagenic; Phototoxic

Indexed keywords

6',7' DIHYDROXY BERGAMOTTIN; BERGAMOTTIN; BERGAPTEN; BERGAPTOL; CYTOCHROME P450 3A4; FUROCOUMARIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOCHEMICAL COMPOSITION; CONTROLLED STUDY; CYTOTOXICITY TEST; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; GENOTOXICITY; GRAPEFRUIT JUICE; HUMAN; HUMAN CELL; IC 50; LIVER MICROSOME; MICRONUCLEUS TEST; MUTAGENICITY; PHOTOTOXICITY; STRUCTURE ANALYSIS; ULTRAVIOLET A RADIATION;

ANIMALS; BEVERAGES; CELL LINE; CITRUS PARADISI; CRICETINAE; CYTOCHROME P-450 CYP3A; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MICROSOMES, LIVER; MUTAGENICITY TESTS; MUTAGENS; PSORALENS; ULTRAVIOLET RAYS;

CITRUS X PARADISI;

EID: 84856505716     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.11.023     Document Type: Article

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