-
1
-
-
77954087303
-
Differential androgen receptor signals in different cells explain why androgen-deprivation therapy of prostate cancer fails
-
Niu Y, Chang TM, Yeh S et al. Differential androgen receptor signals in different cells explain why androgen-deprivation therapy of prostate cancer fails. Oncogene 2010; 29: 3593-604.
-
(2010)
Oncogene
, vol.29
, pp. 3593-3604
-
-
Niu, Y.1
Chang, T.M.2
Yeh, S.3
-
2
-
-
65349089474
-
Genomic strategy for targeting therapy in castration-resistant prostate cancer
-
Mendiratta P, Mostaghel E, Guinney J et al. Genomic strategy for targeting therapy in castration-resistant prostate cancer. J Clin Oncol 2009; 27: 2022-9.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2022-2029
-
-
Mendiratta, P.1
Mostaghel, E.2
Guinney, J.3
-
3
-
-
1642475101
-
The adrenal androgen androstenediol is present in prostate cancer tissue after androgen deprivation therapy and activates mutates androgen receptor
-
Mizokami A, Koh E, Fujita H et al. The adrenal androgen androstenediol is present in prostate cancer tissue after androgen deprivation therapy and activates mutates androgen receptor. Cancer Res 2004; 64: 765-71.
-
(2004)
Cancer Res
, vol.64
, pp. 765-771
-
-
Mizokami, A.1
Koh, E.2
Fujita, H.3
-
4
-
-
0141592695
-
Enhanced androgen receptor signaling correlates with the androgen-refractory growth in a newly established MDA PCa 2b-hr human prostate cancer cell subline
-
Hara T, Nakamura K, Araki H et al. Enhanced androgen receptor signaling correlates with the androgen-refractory growth in a newly established MDA PCa 2b-hr human prostate cancer cell subline. Cancer Res 2003; 63: 5622-8.
-
(2003)
Cancer Res
, vol.63
, pp. 5622-5628
-
-
Hara, T.1
Nakamura, K.2
Araki, H.3
-
5
-
-
34250829045
-
Cytochrome P450 2B6 is a growth-inhibitory and prognostic factor for prostate cancer
-
Kumagai J, Fujimura T, Takahashi S et al. Cytochrome P450 2B6 is a growth-inhibitory and prognostic factor for prostate cancer. Prostate 2007; 67: 1029-37.
-
(2007)
Prostate
, vol.67
, pp. 1029-1037
-
-
Kumagai, J.1
Fujimura, T.2
Takahashi, S.3
-
6
-
-
0023929834
-
Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 β-hydroxylase cytochrome P-450 enzyme
-
Waxman DJ, Attisano C, Guengerich P et al. Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 β-hydroxylase cytochrome P-450 enzyme. Arch Biochem Biophys 1988; 263: 424-36.
-
(1988)
Arch Biochem Biophys
, vol.263
, pp. 424-436
-
-
Waxman, D.J.1
Attisano, C.2
Guengerich, P.3
-
7
-
-
0026001618
-
Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s
-
Waxman DJ, Lapenson DP, Aoyama T et al. Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s. Arch Biochem Biophys 1991; 290: 160-6.
-
(1991)
Arch Biochem Biophys
, vol.290
, pp. 160-166
-
-
Waxman, D.J.1
Lapenson, D.P.2
Aoyama, T.3
-
8
-
-
0018750559
-
3 steroid metabolite in the rat ventral prostate: 5α-androstane-3β, 6α, 17β-triol
-
3 steroid metabolite in the rat ventral prostate: 5α-androstane-3β, 6α, 17β-triol. Steroids 1979; 33: 639-57.
-
(1979)
Steroids
, vol.33
, pp. 639-657
-
-
Isaacs, J.T.1
McDermott, I.R.2
Coffey, D.S.3
-
9
-
-
0018761837
-
Characterization of two new enzymatic activities of the rat ventral prostate: 5α-androstane-3β, 6α, 17β-diol 6α-hydroxylase and 5α-androstane-3β, 6α, 17β-diol 7α -hydroxylase
-
Isaacs JT, McDermott IR, Coffey DS. Characterization of two new enzymatic activities of the rat ventral prostate: 5α-androstane-3β, 6α, 17β-diol 6α-hydroxylase and 5α-androstane-3β, 6α, 17β-diol 7α -hydroxylase. Steroids 1979; 33: 675-92.
-
(1979)
Steroids
, vol.33
, pp. 675-692
-
-
Isaacs, J.T.1
McDermott, I.R.2
Coffey, D.S.3
-
10
-
-
0023645414
-
Isolation and catalytic activity of Cytochrome P-450 from ventral prostate of control rats
-
Sundin M, Warner M, Haaparanta T et al. Isolation and catalytic activity of Cytochrome P-450 from ventral prostate of control rats. J Biol Chem 1987; 262: 12293-7.
-
(1987)
J Biol Chem
, vol.262
, pp. 12293-12297
-
-
Sundin, M.1
Warner, M.2
Haaparanta, T.3
-
11
-
-
4444278991
-
The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes
-
Parkinson A, Mudra DR, Johnson C et al. The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes. Toxicol Appl Pharmacol 2004; 199: 193-209.
-
(2004)
Toxicol Appl Pharmacol
, vol.199
, pp. 193-209
-
-
Parkinson, A.1
Mudra, D.R.2
Johnson, C.3
-
12
-
-
67651083423
-
Expression of cytochrome P450 3A4 and its clinical significance in human prostate cancer
-
Fujimura T, Takahashi S, Urano T et al. Expression of cytochrome P450 3A4 and its clinical significance in human prostate cancer. Urology 2009; 74: 391-7.
-
(2009)
Urology
, vol.74
, pp. 391-397
-
-
Fujimura, T.1
Takahashi, S.2
Urano, T.3
-
13
-
-
69749083669
-
Nuclear receptors CAR and PXR: molecular, functional, and biochemical aspects
-
Di Masi A, De Marinis E, Ascenzi P et al. Nuclear receptors CAR and PXR: molecular, functional, and biochemical aspects. Mol Aspects Med 2009; 30: 297-343.
-
(2009)
Mol Aspects Med
, vol.30
, pp. 297-343
-
-
Di Masi, A.1
De Marinis, E.2
Ascenzi, P.3
-
14
-
-
0032532134
-
SXR, a novel steroid and xenobiotic- sensing nuclear receptor
-
Blumberg B, Sabbagh W, Juguilon H et al. SXR, a novel steroid and xenobiotic- sensing nuclear receptor. Genes Dev 1998; 12: 3195-205.
-
(1998)
Genes Dev
, vol.12
, pp. 3195-3205
-
-
Blumberg, B.1
Sabbagh, W.2
Juguilon, H.3
-
15
-
-
59249083801
-
Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cells
-
Verma S, Tabb MM, Blumberg B. Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cells. BMC Cancer 2009; 9: 3.
-
(2009)
BMC Cancer
, vol.9
, pp. 3
-
-
Verma, S.1
Tabb, M.M.2
Blumberg, B.3
-
16
-
-
77953260492
-
Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells
-
Ouyang N, Ke S, Eagleton N et al. Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells. Br J Cancer 2010; 102: 1753-61.
-
(2010)
Br J Cancer
, vol.102
, pp. 1753-1761
-
-
Ouyang, N.1
Ke, S.2
Eagleton, N.3
-
17
-
-
33745210139
-
Steroid and xenobiotic receptor SXR mediates vitamin K2 activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells
-
Ichikawa T, Horie-Inoue K, Ikeda K et al. Steroid and xenobiotic receptor SXR mediates vitamin K2 activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells. J Biol Chem 2006; 281: 16927-34.
-
(2006)
J Biol Chem
, vol.281
, pp. 16927-16934
-
-
Ichikawa, T.1
Horie-Inoue, K.2
Ikeda, K.3
-
18
-
-
0036356258
-
The generation of monoclonal antibodies against human peroxisome proliferator-activated receptors (PPARs)
-
Tanaka T, Takeno T, Watanabe Y et al. The generation of monoclonal antibodies against human peroxisome proliferator-activated receptors (PPARs). J Atheroscler Thromb 2002; 9: 233-42.
-
(2002)
J Atheroscler Thromb
, vol.9
, pp. 233-242
-
-
Tanaka, T.1
Takeno, T.2
Watanabe, Y.3
-
19
-
-
77949589143
-
Differential expression of estrogen-related receptors β and γ and their clinical significance in human prostate cancer
-
Fujimura T, Takahashi S, Urano T et al. Differential expression of estrogen-related receptors β and γ and their clinical significance in human prostate cancer. Cancer Sci 2010; 101: 646-51.
-
(2010)
Cancer Sci
, vol.101
, pp. 646-651
-
-
Fujimura, T.1
Takahashi, S.2
Urano, T.3
-
20
-
-
0027394794
-
Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer
-
Allred DC, Clark GM, Elledge R et al. Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer. J Natl Cancer Inst 1993; 85: 200-6.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 200-206
-
-
Allred, D.C.1
Clark, G.M.2
Elledge, R.3
-
21
-
-
78649891122
-
Pregnane X receptor as a therapeutic target to inhibit androgen activity
-
Zang B, Cheng Q, Ou Z et al. Pregnane X receptor as a therapeutic target to inhibit androgen activity. Endocrinology 2010; 151: 5721-9.
-
(2010)
Endocrinology
, vol.151
, pp. 5721-5729
-
-
Zang, B.1
Cheng, Q.2
Ou, Z.3
-
22
-
-
67349105004
-
Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor
-
Harmsen S, Meijerman I, Beijnen JH et al. Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor. Cancer Chemother Pharmacol 2009; 64: 35-43.
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, pp. 35-43
-
-
Harmsen, S.1
Meijerman, I.2
Beijnen, J.H.3
-
23
-
-
12344254089
-
Endocrine treatment of prostate cancer
-
Tammela T. Endocrine treatment of prostate cancer. J Steroid Biochem Mol Biol 2004; 92: 287-95.
-
(2004)
J Steroid Biochem Mol Biol
, vol.92
, pp. 287-295
-
-
Tammela, T.1
-
24
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
Tannock IF, de Wit R, Berry WR et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med 2004; 351: 1502-12.
-
(2004)
N Engl J Med
, vol.351
, pp. 1502-1512
-
-
Tannock, I.F.1
de Wit, R.2
Berry, W.R.3
|