Coleus forskohlii extract induces hepatic cytochrome P450 enzymes in mice

Food and Chemical Toxicology

Volumn 50, Issue 3-4, 2012, Pages 750-755

  Virgona, Nantiga ^a,b   Yokotani, Kaori ^a,f   Yamazaki, Yuko ^c   Shimura, Fumio ^c   Chiba, Tsuyoshi ^a   Taki, Yuko ^d   Yamada, Shizuo ^d   Shinozuka, Kazumasa ^e   Murata, Masatsune ^f   Umegaki, Keizo ^a  

^a NATIONAL INSTITUTE OF HEALTH AND NUTRITION   (Japan)

^b UNIVERSITY OF SYDNEY   (Australia)

^c JUMONJI UNIVERSITY   (Japan)

^d UNIVERSITY OF SHIZUOKA   (Japan)

^e MUKOGAWA WOMEN'S UNIVERSITY   (Japan)

^f OCHANOMIZU UNIVERSITY   (Japan)

Author keywords

Coleus forskohlii; Cytochrome p450; Dietary supplement; Drug herb interaction; Forskolin

Indexed keywords

COLEUS FORSKOHLII EXTRACT; CYTOCHROME P450; CYTOCHROME P450 2B; CYTOCHROME P450 2C; CYTOCHROME P450 3A; FORSKOLIN; GLUTATHIONE TRANSFERASE; MESSENGER RNA; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; COLEUS; COLEUS FORSKOHLII; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG SAFETY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INDUCTION; ENZYME LOCALIZATION; GENE EXPRESSION REGULATION; IN VIVO STUDY; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; UPREGULATION;

ANIMALS; BASE SEQUENCE; COLEUS; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; ENZYME INDUCTION; GLUTATHIONE TRANSFERASE; LIVER; MALE; MICE; MICE, INBRED ICR; MICROSOMES, LIVER; ORGAN SIZE; PLANT EXTRACTS; PLANT ROOTS; REAL-TIME POLYMERASE CHAIN REACTION;

MUS; PLECTRANTHUS BARBATUS;

EID: 84856488075     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.11.054     Document Type: Article

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