Towards a better understanding of causation and consequences

Nature Reviews Endocrinology

Volumn 8, Issue 2, 2012, Pages 70-72

  Stowasser, Michael ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

18 HYDROXYHYDROCORTISONE; 18 OXOHYDROCORTISONE; ANGIOTENSIN II; C REACTIVE PROTEIN; CALCIUM ION; GLUCOCORTICOID; STEROID 11BETA MONOOXYGENASE; STEROID 17ALPHA MONOOXYGENASE; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; KCNJ5 PROTEIN, HUMAN;

ADRENAL HYPERPLASIA; CELL PROLIFERATION; EMBRYO CELL; ESSENTIAL HYPERTENSION; HORMONE BLOOD LEVEL; HUMAN; HYPERTENSION; KIDNEY CELL; PATHOPHYSIOLOGY; PRIMARY HYPERALDOSTERONISM; PRIORITY JOURNAL; REVIEW; SODIUM EXCRETION; SOMATIC MUTATION; ZONA FASCICULATA; ZONA GLOMERULOSA; ANIMAL; BIOLOGICAL MODEL; COMPREHENSION; ENDOCRINOLOGY; GENETIC PREDISPOSITION; GENETICS; HYPERALDOSTERONISM; METHODOLOGY; MUTATION; PHYSIOLOGY; RISK FACTOR;

ANIMALS; COMPREHENSION; ENDOCRINOLOGY; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERALDOSTERONISM; MODELS, BIOLOGICAL; MUTATION; RISK FACTORS;

EID: 84856449233     PISSN: 17595029     EISSN: 17595037     Source Type: Journal    
DOI: 10.1038/nrendo.2011.223     Document Type: Review

References (10)

1. Sutherland, D. J., Ruse, J. L. & Laidlaw, J. C. Hypertension, increased aldosterone secretion and low plasma renin activity relieved bydexamethasone. Can. Med. Assoc. J. 95, 1109-1119 (1966).
2. Lifton, R. P. et al. Hereditary hypertension caused by chimaeric gene duplications and ectopic expression of aldosterone synthase. Nat. Genet. 2, 66-74 (1992).
3. Stowasser, M., Pimenta, E. & Gordon, R. D. Familial or genetic primary aldosteronism and Gordon syndrome. Endocrinol. Metab. Clin. North Am. 40, 343-368, viii (2011).
4. Mulatero, P. et al. Prevalence and characteristics of familial hyperaldosteronism: the PATOGEN study (Primary Aldosteronism in TOrino-GENetic forms). Hypertension 58, 797-803 (2011).
5. Choi, M. et al. K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension. Science 331, 768-772 (2011).
6. Geller, D. S. et al. A novel form of human mendelian hypertension featuring nonglucocorticoid-remediable aldosteronism. J. Clin. Endocrinol. Metab. 93, 3117-3123 (2008).
7. Gordon, R. D., Hamlet, S. M., Tunny, T. J. & Klemm, S. A. Aldosterone-producing adenomas responsive to angiotensin pose problems in diagnosis. Clin. Exp. Pharmacol. Physiol. 14, 175-179 (1987). (Pubitemid 18002635)
8. Tunny, T. J., Gordon, R. D., Klemm, S. A. & Cohn, D. Histological and biochemical distinctiveness of atypical aldosterone-producing adenomas responsive to upright posture and angiotensin. Clin. Endocrinol. (Oxf.) 34, 363-369 (1991).
9. Wu, V. C. et al. Endothelial progenitor cells in primary aldosteronism: a biomarker of severity for aldosterone vasculopathy and prognosis. J. Clin. Endocrinol. Metab. 96, 3175-3183 (2011).
10. Pimenta, E. et al. Cardiac dimensions are largely determined by dietary salt in patients with primary aldosteronism: results of a case-control study. J. Clin. Endocrinol. Metab. 96, 2813-2820 (2011). condition10