Anticonvulsant profile of caprylic acid, a main constituent of the medium-chain triglyceride (MCT) ketogenic diet, in mice

Neuropharmacology

Volumn 62, Issue 4, 2012, Pages 1882-1889

  Wlaź, Piotr ^a   Socała, Katarzyna ^a   Nieoczym, Dorota ^a   Łuszczki, Jarogniew J ^b,c   Arnowska, Iwona ^b   Arnowski, Tomasz ^b   Czuczwar, Stanisław J ^b,c   Gasior, MacIej ^d  

^a MARIA CURIE SK ODOWSKA UNIVERSITY   (Poland)

^b MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^c INSTITUTE OF AGRICULTURAL MEDICINE   (Poland)

^d BRISTOL MYERS SQUIBB   (United States)

Author keywords

6 Hz seizure test; Brain concentrations; Ketogenic diet; Maximal electroshock; Pentylenetetrazole; Seizure thresholds tests

Indexed keywords

ANTICONVULSIVE AGENT; MEDIUM CHAIN TRIACYLGLYCEROL; OCTANOIC ACID; PENTETRAZOLE; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; DRUG STRUCTURE; ELECTRIC SHOCK; EPILEPSY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KETOGENIC DIET; MALE; MOTOR COORDINATION; MOTOR PERFORMANCE; MOUSE; MYOCLONUS SEIZURE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; SEIZURE; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; ANTICONVULSANTS; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; EPILEPSY; MALE; MICE; OCTANOIC ACIDS; VALPROIC ACID;

EID: 84856435326     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.12.015     Document Type: Article

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