Development and validation of a reverse phase HPLC method for the determination of caprylic acid in formulations of therapeutic immunoglobulins and its application to antivenom production

Biologicals

Volumn 37, Issue 4, 2009, Pages 230-234

  Herrera, María ^a   Meneses, Fabricio ^a   Gutiérrez, José María ^a   León, Guillermo ^a  

^a UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

Antivenom; Caprylic acid; Diafiltration; HPLC; Therapeutic immunoglobulin

Indexed keywords

IMMUNOGLOBULIN; OCTANOIC ACID; PROTEIN DERIVATIVE; SNAKE VENOM ANTISERUM;

ACCURACY; ARTICLE; CENTRIFUGATION; DRUG SCREENING; DRUG SYNTHESIS; MOLECULAR WEIGHT; PRIORITY JOURNAL; QUALITY CONTROL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAFILTRATION; ULTRAVIOLET RADIATION; VALIDATION STUDY;

ANIMALS; ANTIVENINS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HORSES; IMMUNOGLOBULINS; OCTANOIC ACIDS; PHARMACEUTICAL PREPARATIONS; SENSITIVITY AND SPECIFICITY;

EQUIDAE;

EID: 67650602113     PISSN: 10451056     EISSN: 10958320     Source Type: Journal    
DOI: 10.1016/j.biologicals.2009.02.020     Document Type: Article

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