Glucose and insulin modify thrombospondin 1 expression and secretion in primary adipocytes from diet-induced obese rats

Journal of Physiology and Biochemistry

Volumn 67, Issue 3, 2011, Pages 453-461

  Garcia Diaz, Diego F ^a   Arellano, Arianna V ^a   Milagro, Fermin I ^a   Moreno Aliaga, Maria Jesus ^a   Portillo, Maria Puy ^a   Martinez, J Alfredo ^a   Campion, Javier ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Adipokine; Adipose tissue; Cell culture; Diet induced obesity

Indexed keywords

GLUCOSE; GLYCEROL; INSULIN; LACTIC ACID; THROMBOSPONDIN 1;

ADIPOCYTE; ANIMAL; ARTICLE; BLOOD; BODY WEIGHT; CELL CULTURE; CELL SURVIVAL; GENE EXPRESSION; GENETICS; GLUCOSE BLOOD LEVEL; LIPID DIET; MALE; METABOLISM; OBESITY; PATHOLOGY; PHYSIOLOGY; PRIMARY CELL CULTURE; RAT; SECRETION; WISTAR RAT;

ADIPOCYTES; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CELL SURVIVAL; CELLS, CULTURED; DIET, HIGH-FAT; GENE EXPRESSION; GLUCOSE; GLYCEROL; INSULIN; LACTIC ACID; MALE; OBESITY; PRIMARY CELL CULTURE; RATS; RATS, WISTAR; THROMBOSPONDIN 1;

EID: 84856401223     PISSN: 11387548     EISSN: 18778755     Source Type: Journal    
DOI: 10.1007/s13105-011-0081-7     Document Type: Article

References (42)

1. Alessi MC, Bastelica D, Morange P, Berthet B, Leduc I, Verdier M, Geel O, Juhan-Vague I (2000) Plasminogen activator inhibitor 1, transforming growth factor-beta1, and BMI are closely associated in human adipose tissue during morbid obesity. Diabetes 49:1374-1380 (Pubitemid 30624239)
2. Bhattacharyya S, Marinic TE, Krukovets I, Hoppe G, Stenina OI (2008) Cell type-specific post-transcriptional regulation of production of the potent antiangiogenic and proatherogenic protein thrombospondin-1 by high glucose. J Biol Chem 283:5699-5707
3. Boque N, Campion J, Milagro FI, Moreno-Aliaga MJ, Martinez JA (2009) Some cyclin-dependent kinase inhibitors-related genes are regulated by vitamin C in a model of diet-induced obesity. Biol Pharm Bull 32:1462-1468
4. Boque N, Campion J, Paternain L, Garcia-Diaz DF, Galarraga M, Portillo MP, Milagro FI, Ortiz de Solorzano C, Martinez JA (2009) Influence of dietary macronutrient composition on adiposity and cellularity of different fat depots in Wistar rats. J Physiol Biochem 65:387-395
5. Bornstein P (2001) Thrombospondins as matricellular modulators of cell function. J Clin Invest 107:929-934
6. Bornstein P, Sage EH (1994) Thrombospondins. Methods Enzymol 245:62-85
7. Brandt R, Keston AS (1965) Synthesis of diacetyldichlorofluorescin: a stable reagent for fluorometric analysis. Anal Biochem 11:6-9
8. Bray GA (2004) Medical consequences of obesity. J Clin Endocrinol Metab 89:2583-2589
9. Campion J, Martinez JA (2004) Ketoconazole, an antifungal agent, protects against adiposity induced by a cafeteria diet. Horm Metab Res 36:485-491 (Pubitemid 39119254)
10. Carlson CB, Lawler J, Mosher DF (2008) Structures of thrombospondins. Cell Mol Life Sci 65:672-686
11. Chen H, Sottile J, Strickland DK, Mosher DF (1996) Binding and degradation of thrombospondin-1 mediated through heparan sulphate proteoglycans and low-density-lipoprotein receptor-related protein: localization of the functional activity to the trimeric N-terminal heparin-binding region of thrombospondin-1. Biochem J 318:959-963 (Pubitemid 26320965)
12. Chen H, Strickland DK, Mosher DF (1996) Metabolism of thrombospondin 2. Binding and degradation by 3 t3 cells and glycosaminoglycan-variant Chinese hamster ovary cells. J Biol Chem 271:15993-15999 (Pubitemid 26236211)
13. Crawford SE, Stellmach V, Murphy-Ullrich JE, Ribeiro SM, Lawler J, Hynes RO, Boivin GP, Bouck N (1998) Thrombospondin-1 is a major activator of TGF-beta1 in vivo. Cell 93:1159-1170 (Pubitemid 28307421)
14. DiPietro LA, Nebgen DR, Polverini PJ (1994) Down-regulation of endothelial cell thrombospondin 1 enhances in vitro angiogenesis. J Vasc Res 31:178-185 (Pubitemid 24152427)
15. Fantuzzi G (2005) Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol 115:911-919
16. Ferrante AW (2007) Obesity-induced inflammation: a metabolic dialogue in the language of inflammation. J Intern Med 262:408-414
17. Fu J, Liang X, Chen Y, Tang L, Zhang QH, Dong Q (2008) Oxidative stress as a component of chromium-induced cytotoxicity in rat calvarial osteoblasts. Cell Biol Toxicol 24:201-212
18. Garcia-Diaz DF, Campion J, Milagro FI, Boque N, Moreno-Aliaga MJ, Martinez JA (2010) Vitamin C inhibits leptin secretion and some glucose/lipid metabolic pathways in primary rat adipocytes. J Mol Endocrinol 45:33-43
19. Hong H, Liu LP, Liao JM, Wang TS, Ye FY, Wu J, Wang YY, Wang Y, Li YQ, Long Y, Xia YZ (2009) Down-regulation of LRP1 [correction of LPR1] at the blood-brain barrier in streptozotocin-induced diabetic mice. Neuropharmacology 56:1054-1059
20. Iruela-Arispe ML, Lombardo M, Krutzsch HC, Lawler J, Roberts DD (1999) Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats. Circulation 100:1423-1431 (Pubitemid 29451703)
21. Jaffe EA, Ruggiero JT, Leung LK, Doyle MJ, McKeown-Longo PJ, Mosher DF (1983) Cultured human fibroblasts synthesize and secrete thrombospondin and incorporate it into extracellular matrix. Proc Natl Acad Sci USA 80:998-1002 (Pubitemid 13118075)
22. Jaffe EA, Ruggiero JT, Falcone DJ (1985) Monocytes and macrophages synthesize and secrete thrombospondin. Blood 65:79-84 (Pubitemid 15191041)
23. Jimenez B, Volpert OV, Crawford SE, Febbraio M, Silverstein RL, Bouck N (2000) Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1. Nat Med 6:41-48 (Pubitemid 30048524)
24. Kanda S, Shono T, Tomasini-Johansson B, Klint P, Saito Y (1999) Role of thrombospondin-1-derived peptide, 4N1K, in FGF-2-induced angiogenesis. Exp Cell Res 252:262-272 (Pubitemid 29530257)
25. Maier KG, Han X, Sadowitz B, Gentile KL, Middleton FA, Gahtan V (2010) Thrombospondin-1: a proatherosclerotic protein augmented by hyperglycemia. J Vasc Surg 51:1238-1247
26. Maile LA, Allen LB, Hanzaker CF et al (2010) Glucose regulation of thrombospondin and its role in themodulation of smooth muscle cell proliferation. Exp Diabetes Res pii:617052
27. McKeown-Longo PJ, Hanning R, Mosher DF (1984) Binding and degradation of platelet thrombospondin by cultured fibroblasts. J Cell Biol 98:22-28 (Pubitemid 14220463)
28. McLaren KM (1983) Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets. J Clin Pathol 36:197-199
29. Mertens I, Verrijken A, Michiels JJ, Van der Planken M, Ruige JB, Van Gaal LF (2006) Among inflammation and coagulation markers, PAI-1 is a true component of the metabolic syndrome. Int J Obes 30:1308-1314 (Pubitemid 44141622)
30. Mosher DF, Doyle MJ, Jaffe EA (1982) Synthesis and secretion of thrombospondin by cultured human endothelial cells. J Cell Biol 93:343-348 (Pubitemid 12014123)
31. Murphy-Ullrich JE, Poczatek M (2000) Activation of latent TGF-beta by thrombospondin-1: mechanisms and physiology. Cytokine Growth Factor Rev 11:59-69 (Pubitemid 30169726)
32. Okuno M, Arimoto E, Nishizuka M, Nishihara T, Imagawa M (2002) Isolation of up- or down-regulated genes in PPARgamma-expressing NIH-3T3 cells during differentiation into adipocytes. FEBS Lett 519:108-112 (Pubitemid 34522001)
33. Racher AJ, Looby D, Griffiths JB (1990) Use of lactate dehydrogenase release to assess changes in culture viability. Cytotechnology 3:301-307
34. Raman P, Krukovets I, Marinic TE, Bornstein P, Stenina OI (2007) Glycosylation mediates up-regulation of a potent antiangiogenic and proatherogenic protein, thrombospondin-1, by glucose in vascular smooth muscle cells. J Biol Chem 282:5704-5714 (Pubitemid 47093782)
35. Ramis JM, Franssen-van Hal NL, Kramer E, Llado I, Bouillaud F, Palou A, Keijer J (2002) Carboxypeptidase E and thrombospondin-1 are differently expressed in subcutaneous and visceral fat of obese subjects. Cell Mol Life Sci 59:1960-1971 (Pubitemid 36015868)
36. Riessen R, Kearney M, Lawler J, Isner JM (1998) Immunolocalization of thrombospondin-1 in human atherosclerotic and restenotic arteries. Am Heart J 135:357-364 (Pubitemid 28139180)
37. Samad F, Yamamoto K, Pandey M, Loskutoff DJ (1997) Elevated expression of transforming growth factor-beta in adipose tissue from obese mice. Mol Med 3:37-48 (Pubitemid 27142523)
38. Sheibani N, Frazier WA (1995) Thrombospondin 1 expression in transformed endothelial cells restores a normal phenotype and suppresses their tumorigenesis. Proc Natl Acad Sci USA 92:6788-6792
39. Stenina OI, Krukovets I, Wang K, Zhou Z, Forudi F, Penn MS, Topol EJ, Plow EF (2003) Increased expression of thrombospondin-1 in vessel wall of diabetic Zucker rat. Circulation 107:3209-3215 (Pubitemid 36793093)
40. Topol EJ, McCarthy J, Gabriel S, Moliterno DJ, Rogers WJ, Newby LK, Freedman M, Metivier J, Cannata R, O'Donnell CJ, Kottke-Marchant K, Murugesan G, Plow EF, Stenina O, Daley GQ (2001) Single nucleotide polymorphisms in multiple novel thrombospondin genes may be associated with familial premature myocardial infarction. Circulation 104:2641-2644
41. Varma V, Yao-Borengasser A, Bodles AM, Rasouli N, Phanavanh B, Nolen GT, Kern EM, Nagarajan R, Spencer HJ 3rd, Lee MJ, Fried SK, McGehee RE Jr, Peterson CA, Kern PA (2008) Thrombospondin-1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance. Diabetes 57:432-439
42. Yamanouchi J, Takatori A, Nishida E, Kawamura S, Yoshikawa Y (2002) Expression of lipoprotein receptors in the aortic walls of diabetic APA hamsters. Exp Anim 51:33-41 (Pubitemid 135695654)