Synthesis, pharmacological evaluation and molecular docking studies of indanone derivatives

Medicinal Chemistry Research

Volumn 21, Issue 12, 2012, Pages 4403-4411

  Patel, Ankur ^a   Giles, D ^a   Basavarajaswamy, Guru ^a   Sreedhar, C ^a   Patel, Avani ^a  

^a ACHARYA AND B M REDDY COLLEGE OF PHARMACY   (India)

Author keywords

Analgesic; Anti inflammatory; Antimicrobial; Docking; Indanone; Isoxazole

Indexed keywords

3 (4 CHLOROPHENYL) 4H INDENO[1,2 C][1,2]ISOXAZOL 4 ONE; 3 (4 HYDROXYPHENYL) 4H INDENO[1,2 C][1,2]ISOXAZOLE 4 ONE; 3 (4 METHYLPHENYL) 4H INDENO[1,2 C][1,2]ISOXAZOL 4 ONE; 3 (4 NITROPHENYL) 4H INDENO[1,2 C][1,2]ISOXAZOL 4 ONE; 3 PHENYL 4H INDENO[1,2 C][1,2]ISOXAZOL 4 ONE; 3 [4 (DIMETHYLAMINO)PHENYL] 4H INDENO[1,2 C][1,2]ISOXAZOL 4 ONE; AMPICILLIN; ANALGESIC AGENT; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; DICLOFENAC; FLUCONAZOLE; INDANONE DERIVATIVE; INDOMETACIN; ISOXAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; BACILLUS SUBTILIS; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG SCREENING; DRUG SYNTHESIS; ESCHERICHIA COLI; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR DOCKING; MOLECULAR MODEL; MOUSE; NONHUMAN; PASPALUM NOTATUM; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STRUCTURE ACTIVITY RELATION; ZONE OF INHIBITION;

EID: 84856382684     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-9973-5     Document Type: Article

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