Synthesis and antimalarial activity of (E) 2-(2′-chloro-3′- quinolinylmethylidene)-5,7-dimethoxyindanones

Letters in Drug Design and Discovery

Volumn 4, Issue 1, 2007, Pages 49-54

  Charris, J E ^a,b   Lobo, G M ^a   Camacho, J ^a   Ferrer, R ^a   Barazarte, A ^a   Dominguez J N ^a   Gamboa, N ^b   Rodrigues, J R ^b   Angel, J E ^c  

^a UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

^b UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

^c UNIVERSIDAD DEL ZULIA   (Venezuela)

Author keywords

Hematin; Indanone; Malaria; P. berghei; Quinoline

Indexed keywords

2 (2' CHLORO 3' QUINOLINYLMETHYLIDENE) 5,7 DIMETHOXYINDANONE DERIVATIVE; 2 (2' CHLORO 5',8' DIMETHYL 3' QUINOLINYLMETHYLIDENE) 5,7 DIMETHOXYINDANONE; 2 (2' CHLORO 5',8' METHYL 3' QUINOLINYLMETHYLIDENE) 5,7 DIMETHOXYINDANONE; 2 (2' CHLORO 6' METHOXY 3' QUINOLINYLMETHYLIDEN) 5,7 DIMETHOXYINDANONE; 2 (2' CHLORO 6' METHYL 3' QUINOLINYLMETHYLIDEN) 5,7 DIMETHOXYINDANONE; 2 (2' CHLORO 6',7' DIMETHOXY 3' QUINOLINYLMETHYLIDEN) 5,7 DIMETHOXYINDANONE; 2 (2' CHLORO 7' METHOXY 3' QUINOLINYLMETHYLIDEN) 5,7 DIMETHOXYINDANONE; 2 (2' CHLORO 7' METHYL 3' QUINOLINYLMETHYLIDENE) 5,7 DIMETHOXYINDANONE; 2 (2' CHLORO 8' METHYL 3' QUINOLINYLMETHYLIDENE) 5,7 DIMETHOXYINDANONE; ANTIMALARIAL AGENT; HEMATIN; HEMOGLOBIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CLAISEN CONDENSATION; CONTROLLED STUDY; DRUG EFFECT; DRUG SYNTHESIS; HYDROLYSIS; MALARIA; MALE; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PRIORITY JOURNAL; SURVIVAL;

EID: 33845973774     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/157018007778992865     Document Type: Article

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