Sex differences in the association between level of childhood interleukin-6 and insulin resistance in adolescence

Experimental Diabetes Research

Volumn 2012, Issue , 2012, Pages

  Bugge, Anna ^a   El Naaman, Bianca ^a   G McMurray, Robert ^b   Froberg, Karsten ^a   Nielsen, Claus Henrik ^c   Müller, Klaus ^c   Andersen, Lars Bo ^a,d  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b University of North Carolina at Chapel Hill   (United States)

^c Rigshospitalet   (Denmark)

^d NORWEGIAN SCHOOL OF SPORT SCIENCES   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

FAT; GLUCOSE; INSULIN; INTERLEUKIN 6; IL6 PROTEIN, HUMAN;

ADOLESCENT; ADOLESCENT DISEASE; ANTHROPOMETRY; ARTICLE; BLOOD SAMPLING; BODY FAT; CHILD; CHILDHOOD DISEASE; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; FEMALE; FITNESS; FOLLOW UP; HUMAN; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SCHOOL CHILD; SEX DIFFERENCE; VENOUS OXYGEN TENSION; BLOOD; OXYGEN CONSUMPTION; SEXUAL DEVELOPMENT; STATISTICAL MODEL;

ADOLESCENT; FEMALE; HUMANS; INSULIN RESISTANCE; INTERLEUKIN-6; LOGISTIC MODELS; MALE; OXYGEN CONSUMPTION; SEX CHARACTERISTICS;

EID: 84856373746     PISSN: 16875214     EISSN: 16875303     Source Type: Journal    
DOI: 10.1155/2012/859186     Document Type: Article

References (36)

1. Tilg H., Moschen A. R., Adipocytokines: mediators linking adipose tissue, inflammation and immunity Nature Reviews Immunology 2006 6 10 772 783 (Pubitemid 44453463)
2. Inadera H., The usefulness of circulating adipokine levels for the assessment of obesity-related health problems International Journal of Medical Sciences 2008 5 5 248 262
3. Weiss R., Caprio S., The metabolic consequences of childhood obesity Best Practice and Research: Clinical Endocrinology and Metabolism 2005 19 3 405 419 (Pubitemid 41263795)
4. Pradhan A. D., Manson J. E., Rifai N., Buring J. E., Ridker P. M., C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus Journal of the American Medical Association 2001 286 3 327 334 (Pubitemid 32656163)
5. Hotamisligil G. S., Inflammation and metabolic disorders Nature 2006 444 7121 860 867 (Pubitemid 46024993)
6. Wallenius V., Wallenius K., Ahrén B., Rudling M., Carlsten H., Dickson S. L., Ohlsson C., Jansson J. O., Interleukin-6-deficient mice develop mature-onset obesity Nature Medicine 2002 8 1 75 79 (Pubitemid 34101732)
7. Kern P. A., Ranganathan S., Li C., Wood L., Ranganathan G., Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance American Journal of Physiology: Endocrinology and Metabolism 2001 280 5 43-5 E745 E751
8. Bastard J. P., Maachi M., van Nhieu J. T., Jardel C., Bruckert E., Grimaldi A., Robert J. J., Capeau J., Hainque B., Adipose tissue IL-6 content correlates with resistance to insulin activation of glucose uptake both in vivo and in vitro Journal of Clinical Endocrinology and Metabolism 2002 87 5 2084 2089 (Pubitemid 34521492)
9. Petersen A. M., Pedersen B. K., The anti-inflammatory effect of exercise Journal of Applied Physiology 2005 98 4 1154 1162 (Pubitemid 40396484)
10. Pedersen B. K., Febbraio M. A., Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis Journal of Applied Physiology 2007 102 2 814 819 (Pubitemid 46220915)
11. Carey A. L., Bruce C. R., Sacchetti M., Anderson M. J., Olsen D. B., Saltin B., Hawley J. A., Febbraio M. A., Interleukin-6 and tumor necrosis factor- are not increased in patients with Type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness Diabetologia 2004 47 6 1029 1037 (Pubitemid 38918162)
12. Thomas N. E., Williams D. R., Inflammatory factors, physical activity, and physical fitness in young people Scandinavian Journal of Medicine and Science in Sports 2008 18 5 543 556
13. Rubin D. A., McMurray R. G., Harrell J. S., Hackney A. C., Thorpe D. E., Haqq A. M., The association between insulin resistance and cytokines in adolescents: the role of weight status and exercise Metabolism 2008 57 5 683 690 (Pubitemid 351608230)
14. Andersen L. B., Mller K., Eiberg S., Froberg K., Andersen J. F. B., Bugge A., Hermansen B. E. N., McMurray R. G., Cytokines and clustered cardiovascular risk factors in children Metabolism 2010 59 4 561 566
15. Steene-Johannessen J., Kolle E., Reseland J. E., Anderssen S. A., Andersen L. B., Waist circumference is related to low-grade inflammation in youth International Journal of Pediatric Obesity 2010 5 4 313 319
16. Nemet D., Wang P., Funahashi T., Matsuzawa Y., Tanaka S., Engelman L., Cooper D. M., Adipocytokines, body composition, and fitness in children Pediatric Research 2003 53 1 148 152 (Pubitemid 36033996)
17. Roth C. L., Kratz M., Ralston M. M., Reinehr T., Changes in adipose-derived inflammatory cytokines and chemokines after successful lifestyle intervention in obese children Metabolism 2011 60 4 445 452
18. Hasselstrm H. A., Karlsson M. K., Hansen S. E., Grnfeldt V., Froberg K., Andersen L. B., A 3-year physical activity intervention program increases the gain in bone mineral and bone width in prepubertal girls but not boys: the prospective Copenhagen School Child Interventions Study (CoSCIS) Calcified Tissue International 2008 83 4 243 250
19. Eiberg S., Hasselstrom H., Grnfeldt V., Froberg K., Svensson J., Andersen L. B., Maximum oxygen uptake and objectively measured physical activity in Danish children 6-7 years of age: the Copenhagen school child intervention study British Journal of Sports Medicine 2005 39 10 725 730 (Pubitemid 41406585)
20. de Lorenzo A., Bertini I., Candeloro N., Iacopino L., Andreoli A., Van L., Comparison of different techniques to measure body composition in moderately active adolescents British Journal of Sports Medicine 1998 32 3 215 219 (Pubitemid 28446077)
21. Durnin J. V., Rahaman M. M., The assessment of the amount of fat in the human body from measurements of skinfold thickness. 1967 The British Journal of Nutrition 2003 89 1 147 155
22. Tanner J. M., Growth at Adolescence 1962 Oxford, Uk Blackwell Publishing
23. Matthews D. R., Hosker J. P., Rudenski A. S., Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 1985 28 412 419 (Pubitemid 15018832)
24. McLaughlin J. E., King G. A., Howley E. T., Bassett D. R. Jr., Ainsworth B. E., Validation of the COSMED K4 b2 portable metabolic system International Journal of Sports Medicine 2001 22 4 280 284 (Pubitemid 32476608)
25. Jensen K., Jrgensen S., Johansen L., A metabolic cart for measurement of oxygen uptake during human exercise using inspiratory flow rate European Journal of Applied Physiology 2002 87 3 202 206 (Pubitemid 41398995)
26. Rowland T. W., Developmental Exercise Physiology 1996 Champaign, Ill, USA Human Kinetics Books
27. Galcheva S. V., Iotova V. M., Yotov Y. T., Bernasconi S., Street M. E., Circulating proinflammatory peptides related to abdominal adiposity and cardiometabolic risk factors in healthy prepubertal children European Journal of Endocrinology 2011 164 4 553 558
28. Andersen L. B., Sardinha L. B., Froberg K., Riddoch C. J., Page A. S., Anderssen S. A., Fitness, fatness and clustering of cardiovascular risk factors in children from Denmark, Estonia and Portugal: the European Youth Heart Study International Journal of Pediatric Obesity 2008 3 supplement 1 58 66 (Pubitemid 351285469)
29. Halle M., Korsten-Reck U., Wolfarth B., Berg A., Low-grade systemic inflammation in overweight children: impact of physical fitness Exercise Immunology Review 2004 10 66 74
30. Rubin D. A., McMurray R. G., Harrell J. S., Hackney A. C., Haqq A. M., Do surrogate markers for adiposity relate to cytokines in adolescents? Journal of Investigative Medicine 2008 56 5 786 792
31. Nagel G., Rapp K., Wabitsch M., Bchele G., Kroke A., Zllner I., Weiland S. K., Koenig W., Prevalence and cluster of cardiometabolic biomarkers in overweight and obese schoolchildren: results from a large survey in Southwest Germany Clinical Chemistry 2008 54 2 317 325 (Pubitemid 351302634)
32. Caballero A. E., Bousquet-Santos K., Robles-Osorio L., Montagnani V., Soodini G., Porramatikul S., Hamdy O., Nobrega A. C. L., Horton E. S., Overweight latino children and adolescents have marked endothelial dysfunction and subclinical vascular inflammation in association with excess body fat and insulin resistance Diabetes Care 2008 31 3 576 582
33. Tam C. S., Garnett S. P., Cowell C. T., Heilbronn L. K., Lee J. W., Wong M., Baur L. A., IL-6, IL-8 and IL-10 levels in healthy weight and overweight children Hormone Research in Paediatrics 2010 73 2 128 134
34. Thorand B., Baumert J., Dring A., Herder C., Kolb H., Rathmann W., Giani G., Koenig W., Wichmann H. E., Lwel H., Meisinger C., Illig T., Holle R., John J., Sex differences in the relation of body composition to markers of inflammation Atherosclerosis 2006 184 1 216 224 (Pubitemid 41721091)
35. Thorand B., Baumert J., Kolb H., Meisinger C., Chambless L., Koenig W., Herder C., Sex differences in the prediction of type 2 diabetes by inflammatory markers: results from the MONICA/KORA Augsburg case-cohort study, 19842002 Diabetes Care 2007 30 4 854 860 (Pubitemid 46556577)
36. Andersen L. B., Bugge A., Dencker M., Eiberg S., El-Naaman B., The association between physical activity, physical fitness and development of metabolic disorders International Journal of Pediatric Obesity 2011 6 supplement 1 29 34