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Volumn 109, Issue 3, 2012, Pages 649-650

Gaining confidence in high-throughput screening

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENT DYE; G PROTEIN COUPLED RECEPTOR; HORSERADISH PEROXIDASE; LIGAND; NEW DRUG; PROTEIN TYROSINE PHOSPHATASE 1B;

EID: 84856369183     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1119350109     Document Type: Note
Times cited : (19)

References (12)
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  • 3
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    • DOI 10.1038/nbt1186, PII NBT1186
    • Malo N, Hanley JA, Cerquozzi S, Pelletier J, Nadon R (2006) Statistical practice in high-throughput screening data analysis. Nat Biotechnol 24:167-175. (Pubitemid 43221699)
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    • Malo, N.1    Hanley, J.A.2    Cerquozzi, S.3    Pelletier, J.4    Nadon, R.5
  • 4
    • 11144320699 scopus 로고    scopus 로고
    • Navigating chemical space for biology and medicine
    • DOI 10.1038/nature03193
    • Lipinski C, Hopkins A (2004) Navigating chemical space for biology and medicine. Nature 432:855-861. (Pubitemid 40037141)
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    • Lipinski, C.1    Hopkins, A.2
  • 5
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    • High-resolution dose-response screening using droplet-based microfluidics
    • Miller OJ, et al. (2011) High-resolution dose-response screening using droplet-based microfluidics. Proc Natl Acad Sci USA 109:378-383.
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    • Miller, O.J.1
  • 6
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    • Improving lead generation success through integrated methods: Transcending 'drug discovery by numbers'
    • Campbell JB (2010) Improving lead generation success through integrated methods: Transcending 'drug discovery by numbers'. IDrugs 13:874-879.
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    • Campbell, J.B.1
  • 7
    • 77649234756 scopus 로고    scopus 로고
    • How to improve R&D productivity: The pharmaceutical industry's grand challenge
    • Paul SM, et al. (2010) How to improve R&D productivity: The pharmaceutical industry's grand challenge. Nat Rev Drug Discov 9:203-214.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 203-214
    • Paul, S.M.1
  • 8
    • 33845491449 scopus 로고    scopus 로고
    • Interpreting steep dose-response curves in early inhibitor discovery
    • Shoichet BK (2006) Interpreting steep dose-response curves in early inhibitor discovery. J Med Chem 49: 7274-7277.
    • (2006) J Med Chem , vol.49 , pp. 7274-7277
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  • 10
    • 77955563148 scopus 로고    scopus 로고
    • Microdroplets in microfluidics: An evolving platform for discoveries in chemistry and biology
    • Theberge AB, et al. (2010) Microdroplets in microfluidics: An evolving platform for discoveries in chemistry and biology. Angew Chem Int Ed Engl 49:5846-5868.
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  • 11
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    • Ultrahigh-throughput screening in drop-based microfluidics for directed evolution
    • Agresti JJ, et al. (2010) Ultrahigh-throughput screening in drop-based microfluidics for directed evolution. Proc Natl Acad Sci USA 107:4004-4009.
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  • 12
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    • Dispersion of soluble matter in solvent flowing slowly through a tube
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.