Studies of the myocardial uptake and excretion mechanisms of a novel 99mTc heart perfusion agent

Nuclear Medicine and Biology

Volumn 39, Issue 2, 2012, Pages 207-213

  Mendes, Filipa ^a   Gano, Lurdes ^a   Fernandes, Célia ^a   Paulo, António ^a   Santos, Isabel ^a  

^a INSTITUTO TECNOLÓGICO E NUCLEAR   (Portugal)

Author keywords

Monocationic 99mTc tricarbonyl complexes; Multidrug resistance; Myocardial perfusion imaging; Subcellular distribution

Indexed keywords

CATION; CYCLOSPORIN A; GLYCOPROTEIN P; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; MULTIDRUG RESISTANCE PROTEIN; RADIOPHARMACEUTICAL AGENT; TECHNETIUM 99M; TETROFOSMIN TC 99M; TMEOP TC 99M; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CELLULAR DISTRIBUTION; CENTRIFUGATION; DRUG ACCUMULATION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG EFFECT; DRUG EXCRETION; DRUG STRUCTURE; DRUG UPTAKE; ECHO PLANAR IMAGING; EX VIVO STUDY; HEART MUSCLE; IN VIVO STUDY; KIDNEY; LIVER; LIVER CLEARANCE; MALE; MITOCHONDRION; MULTIDRUG RESISTANCE; NONHUMAN; PLASMA CLEARANCE; PROTEIN FUNCTION; RAT;

ANIMALS; CYCLOSPORINE; ENZYME INHIBITORS; LIVER; MALE; METABOLIC CLEARANCE RATE; MITOCHONDRIA; MYOCARDIUM; ORGANOTECHNETIUM COMPOUNDS; P-GLYCOPROTEINS; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; TECHNETIUM TC 99M SESTAMIBI; TISSUE DISTRIBUTION;

EID: 84856362049     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2011.08.007     Document Type: Article

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