Technetium-99m-labeled myocardial perfusion agents: Are they better than thallium-201?

Cardiology in Review

Volumn 9, Issue 3, 2001, Pages 160-172

  Kailasnath, Purushothaman ^a   Sinusas, Albert J ^a   Beller, George A ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

Ischemic heart disease; Myocardial perfusion imaging; Technetium 99m labeled tracers; Technetium 99m sestamibi; Thallium 201

Indexed keywords

DITHIOCARBAMIC ACID DERIVATIVE; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; TECHNETIUM 99M; TETROFOSMIN TC 99M; THALLIUM 201; TRACER;

CORONARY ARTERY DISEASE; COST; DIAGNOSTIC VALUE; FLOW RATE; HEART MUSCLE PERFUSION; HUMAN; IMAGING; KINETICS; RADIOISOTOPE DISTRIBUTION; REVIEW; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION;

EID: 0035012919     PISSN: 10615377     EISSN: None     Source Type: Journal    
DOI: 10.1097/00045415-200105000-00009     Document Type: Review

References (119)

1. The extraction of thallium-201 by the myocardium
2. Technetium-99m hexakis 2-methoxy-2-isobutyl isonitrile and thallium-201 extraction, washout, and retention at varying coronary flow rates in rabbit heart
3. Technetium-99m-1,2-bis-[bis(2-ethoxyethyl) phosphino]ethane: Human biodistribution, dosimetry and safety of a new myocardial perfusion imaging agent
4. 201Tl and regional myocardial blood flow
5. Comparative myocardial extraction of two technetium-labeled BATe derivatives (SQ30217, SQ32014) and thallium
6. The relationship between myocardial retention of technetium-99m teboroxime and myocardial blood flow
7. Biodistribution, dosimetry, and safety of myocardial perfusion imaging agent 99mTc-N-NOET in healthy volunteers
8. Technetium-99m hexakis 2-methoxyisobutyl isonitrile: Human biodistribution, dosimetry, safety, and preliminary comparison to thallium-201 for myocardial perfusion imaging
9. Biokinetics of technetium-99m-tetrofosmin: Myocardial perfusion imaging agent: Implications for a one-day imaging protocol
10. 201Tl during dobutamine infusion: Comparison with adenosine stress
11. 99mTc sestamibi uptake during adenosine-induced vasodilation as a function of coronary stenosis severity
12. Effect of ischemia and postischemic dysfunction on myocardial uptake of technetium-99m-labeled methoxyisobutyl isonitrile and thallium-201
13. 201Tl to myocardial blood flow in a canine model of myocardial ischemic insult
14. Technetium-99m-tetrofosmin to assess myocardial blood flow: Experimental validation in an intact canine model of ischemia
15. Limitations of dobutamine for enhancing flow heterogeneity in the presence of single coronary stenosis: Implications for technetium-99m-sestamibi imaging
16. 99mTc sestamibi uptake, and systolic wall thickening in the presence of coronary artery stenoses: Implications for dobutamine stress testing
17. Technetium-99m-sestamibi myocardial perfusion imaging in detection of coronary artery disease: Comparison between initial (1-hour) and delayed (3-hour) postexercise images
18. Heart: Coronary artery disease
19. Redistribution of 99mTc-sestamibi and 201Tl in the presence of a severe coronary artery stenosis
20. Myocardial redistribution of technetium-99m-methoxyisobutyl isonitrile (SESTAMIBI)
21. 99mTc-sestamibi with thallium reinjection and [18F]fluorodeoxyglucose
22. Myocardial viability index in chronic coronary artery disease: Technetium-99m-methoxy isobutyl isonitrile redistribution
23. Myocardial kinetics of TcN-NOET: A neutral lipophilic complex tracer of regional myocardial blood flow
24. Interaction of technetium-99m-N-NOET with blood elements: Potential mechanism of myocardial redistribution
25. Myocardial uptake and redistribution of 99mTc-N-NOET in dogs with either sustained coronary low flow or transient coronary occlusion: Comparison with 201Tl and myocardial blood flow
26. Optimal timing for initial and redistribution technetium 99m-N-NOET image acquisition
27. Quantification of myocardial infarction during coronary occlusion and myocardial salvage after reperfusion using cardiac imaging with technetium-99m hexakis 2-methoxyisobutyl isonitrile
28. Quantification of area at risk during coronary occlusion and degree of myocardial salvage after reperfusion with technetium-99m methoxyisobutyl isonitrile
29. 99mTc-tetrofosmin assessment of myocardial perfusion and viability in canine models of coronary occlusion and reperfusion
30. Thallium 201 kinetics in stunned myocardium characterized by severe postischemic systolic dysfunction
31. Myocardial uptake of thallium and rubidium during alterations in perfusion and oxygenation in isolated rabbit hearts
32. Comparison of technetium 99m methoxy isobutyl isonitrile and thallium 201 for evaluation of coronary artery disease by planar and tomographic methods
33. 99mTc 2-methoxy-isobutyl-isonitrile: A direct comparison in normal individuals and patients with coronary artery disease
34. Technetium-99m-sestamibi myocardial perfusion imaging for evaluation of coronary artery disease
35. Alternative referent standards for cardiac normality: Implications for diagnostic testing
36. Exercise echocardiography or exercise SPECT imaging? A meta-analysis of diagnostic test performance
37. Anatomy of a meta-analysis: A critical review of "Exercise echocardiography or exercise SPECT imaging? A meta-analysis of diagnostic test performance"
38. Gated SPECT with technetium-99m-sestamibi for assessment of myocardial perfusion abnormalities
39. Using gated technetium-99m-sestamibi SPECT to characterize fixed myocardial defects as infarct or artifact
40. 99mTc-sestamibi single-photon emission computed tomography
41. Multicenter clinical trial to evaluate the efficacy of correction for photon attenuation and scatter in SPECT myocardial perfusion imaging
42. Sestamibi and the issue of tissue crosstalk
43. Comparative diagnostic accuracy of TI-201 and Tc-99m sestamibi SPECT imaging (perfusion and ECG-gated SPECT) in detecting coronary artery disease in women
44. Myocardial perfusion imaging and dynamic analysis with technetium-99m tetrofosmin
45. Comparison of myocardial perfusion imaging with technetium-99m tetrofosmin versus thallium-201 in coronary artery disease
46. Planar and tomographic imaging with technetium 99m-labeled tetrofosmin: Correlation with thallium 201 and coronary angiography
47. Myocardial tomography using technetium-99m-tetrofosmin to evaluate coronary artery disease
48. Technetium-99m-tetrofosmin myocardial imaging: A comparison with thallium-201 and angiography
49. 201Tl imaging and coronary angiography in a phase III multicenter trial
50. Technetium 99m-labeled tetrofosmin myocardial tomography in patients with coronary artery disease: Comparison between adenosine and dynamic exercise stress testing
51. Comparison of defect size between thallium-201 and technetium-99m tetrofosmin myocardial single-photon emission computed tomography in patients with single-vessel coronary artery disease
52. Tomographic myocardial imaging with technetium-99m tetrofosmin: Comparison with tetrofosmin and thallium planar imaging and with angiography
53. Comparison of technetium-99m tetrofosmin and thallium-201 single-photon emission computed tomographic imaging for detection of myocardial perfusion defects in patients with coronary artery disease
54. 99mTc-tetrofosmin myocardial tomography in the evaluation of coronary artery disease
55. Combined assessment of regional perfusion and wall motion in patients with coronary artery disease with technetium 99m tetrofosmin
56. Myocardial perfusion imaging with technetium-99m-Tc NOET: Comparison with thallium-201 and coronary angiography
57. Head-to-head comparison between technetium-99m-sestamibi and thallium-201 tomographic imaging for the detection of coronary artery disease using combined dipyridamole-exercise stress
58. Adenosine technetium-99m sestamibi myocardial perfusion SPECT in women: Diagnostic efficacy in detection of coronary artery disease
59. 99mTc-MIBI SPECT: Improved diagnostic yield in coronary artery disease
60. Dobutamine thallium myocardial perfusion tomography
61. Comparison of dobutamine and exercise using technetium-99m sestamibi imaging for the evaluation of coronary artery disease
62. 99mTc-MIBI single-photon emission tomography: Non-exercise-dependent detection of haemodynamically significant coronary artery stenoses
63. 99mTc-MIBI single photon emission computed tomography
64. Synergistic value of simultaneous stress dobutamine sestamibi single-photon-emission computerized tomography and echocardiography in the detection of coronary artery disease
65. Comparison of exercise, dipyridamole, adenosine, and dobutamine stress with the use of Tc-99m tetrofosmin tomographic imaging
66. Comparison of exercise, dipyridamole, and adenosine by use of technetium 99m sestamibi tomographic imaging
67. Prognostic value of thallium-201 myocardial perfusion imaging: A diagnostic tool comes of age
68. Value of early thallium-201 scintigraphy for predicting mortality in patients with acute myocardial infarction
69. Prognostic value of exercise thallium-201 imaging in patients presenting for evaluation of chest pain
70. Prediction of cardiac events after uncomplicated myocardial infarction: A prospective study comparing predischarge exercise thallium-201 scintigraphy and coronary angiography
71. Extent and severity of myocardial hypoperfusion as predictors of prognosis in patients with suspected coronary artery disease
72. Prognostic utility of the exercise thallium-201 test in ambulatory patients with chest pain: Comparison with cardiac catheterization
73. Prognostic significance of normal quantitative planar thallium-201 stress scintigraphy in patients with chest pain
74. Prognostic implications of normal exercise thallium 201 images
75. Prognostic importance of silent myocardial ischemia detected by intravenous dipyridamole thallium myocardial imaging in asymptomatic patients with coronary artery disease
76. Prognostic value of dipyridamole thallium scintigraphy for evaluation of ischemic heart disease
77. Determination of the quantitative thallium imaging variables that optimize detection of coronary artery disease
78. Prognostic importance of thallium uptake by the lungs during exercise in coronary artery disease
79. Increased lung uptake of thallium-201 during exercise myocardial imaging: Clinical, hemodynamic and angiographic implications in patients with coronary artery disease
80. Transient ischemic dilation of the left ventricle on stress thallium-201 scintigraphy: A marker of severe and extensive coronary artery disease
81. Risk assessment using single-photon emission computed tomographic technetium-99m sestamibi imaging
82. Incremental value of prognostic testing in patients with known or suspected ischemic heart disease: A basis for optimal utilization of exercise technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography
83. The noninvasive prediction of cardiac mortality in men and women with known or suspected coronary artery disease
84. Effective risk stratification using exercise myocardial perfusion SPECT in women: Gender-related differences in prognostic nuclear testing
85. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for the prediction of cardiac death: Differential stratification for risk of cardiac death and myocardial infarction
86. Comparative prognostic value of automatic quantitative analysis versus semiquantitative visual analysis of exercise myocardial perfusion single-photon emission computed tomography
87. Survival of medically treated patients in the coronary artery surgery study (CASS) registry
88. Exercise-induced ischemia in mildly symptomatic patients with coronary-artery disease and preserved left ventricular function: Identification of subgroups at risk of death during medical therapy
89. Prognostic value of radionuclide angiography in medically treated patients with coronary artery disease: A comparison with clinical and catheterization variables
90. Determination of cardiac risk by dipyridamole-thallium imaging before peripheral vascular surgery
91. Combining clinical and thallium data optimizes preoperative assessment of cardiac risk before major vascular surgery
92. Dipyridamole thallium-201 scintigraphy as a preoperative screening test: A reexamination of its predictive potential. Study of Perioperative Ischemia Research Group
93. Risk stratification and survival after myocardial infarction
94. Dipyridamole-thallium-201 scintigraphy in the prediction of future cardiac events after acute myocardial infarction
95. Area-at-risk determination by technetium-99m-hexakis-2-methoxyisobutyl isonitrile in experimental reperfused myocardial infarction
96. Quantitative radionuclide assessment of regional ventricular function after thrombolytic therapy for acute myocardial infarction: Results of phase I Thrombolysis in Myocardial Infarction (TIMI) trial
97. Feasibility of tomographic 99mTc-hexakis-2-methoxy-2-methylpropyl-isonitrile imaging for the assessment of myocardial area at risk and the effect of treatment in acute myocardial infarction
98. Role of technetium 99m methoxyisobutylisonitrile single photon emission tomography in the evaluation of thrombolysis in acute myocardial infarction before and after admission to hospital
99. Value of radionuclide rest and exercise left ventricular ejection fraction in assessing survival of patients after thrombolytic therapy for acute myocardial infarction: Results of Thrombolysis in Myocardial Infarction (TIMI) phase II study
100. Comparative value of maximal treadmill testing, exercise thallium myocardial perfusion scintigraphy and exercise radionuclide ventriculography for distinguishing high- and low-risk patients soon after acute myocardial infarction
101. Prediction of multivessel coronary artery disease and prognosis early after acute myocardial infarction by exercise electrocardiography and thallium-201 myocardial perfusion scanning
102. Comparison of early thallium-201 scintigraphy and gated blood pool imaging for predicting mortality in patients with acute myocardial infarction
103. Prospective assessment of regional myocardial perfusion before and after coronary revascularization surgery by quantitative thallium-201 scintigraphy
104. Late reversibility of tomographic myocardial thallium-201 defects: An accurate marker of myocardial viability
105. Enhanced detection of ischemic but viable myocardium by the reinjection of thallium after stress-redistribution imaging
106. Prognostic value of predischarge low-level exercise thallium testing after thrombolytic treatment of acute myocardial infarction
107. Significance of a negative exercise thallium test in the presence of a critical residual stenosis after thrombolysis for acute myocardial infarction
108. Use of exercise technetium-99m sestamibi SPECT imaging to detect residual ischemia and for risk stratification after acute myocardial infarction
109. 99mTc-sestamibi single photon emission computed tomographic imaging 2 to 4 days after acute myocardial infarction predicts in-hospital and postdischarge cardiac events: Comparison with submaximal exercise imaging
110. Redistribution of thallium at rest in patients with stable and unstable angina and the effect of coronary artery bypass surgery
111. Concordance and discordance between stress-redistribution-reinjection and rest-redistribution thallium imaging for assessing viable myocardium: Comparison with metabolic activity by positron emission tomography
112. 201Tl imaging in detection of myocardial viability and prediction of improvement in left ventricular function after coronary bypass surgery in patients with severely depressed left ventricular function
113. 99mTc-sestamibi
114. Positron emission tomography detects evidence of viability in rest technetium-99m sestamibi defects
115. Significance of defect severity in technetium-99m-MIBI SPECT at rest to assess myocardial viability: Comparison with fluorine-18-FDG PET
116. Comparison of rest thallium-201 imaging and rest technetium-99m sestamibi imaging for assessment of myocardial viability in patients with coronary artery disease and severe left ventricular dysfunction
117. Functional assessment with electrocardiographic gated single-photon emission computed tomography improves the ability of technetium-99m sestamibi myocardial perfusion imaging to predict myocardial viability in patients undergoing revascularization
118. Comparison of technetium 99m-tetrofosmin and thallium-201 single photon emission computed tomographic imaging for the assessment of viable myocardium in patients with left ventricular dysfunction
119. Nitrate administration to enhance the detection of myocardial viability by technetium-99m tetrofosmin single-photon emission tomography