Frequency of HLA-DP-specific antibodies and a possible new cross-reacting group

Human Immunology

Volumn 73, Issue 2, 2012, Pages 175-179

  Callender, Carly J ^a   Fernandez Vina, Marcelo ^b   Leffell, Mary S ^a   Zachary, Andrea A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CREG; DP; HLA DP

Indexed keywords

CROSS REACTING ANTIBODY; HLA ANTIBODY; HLA DP ANTIBODY; HLA DP ANTIGEN; HLA DR ANTIGEN; HLA DRB1 ANTIGEN; UNCLASSIFIED DRUG;

ARTICLE; CROSS REACTION; CYTOTOXICITY; FEMALE; HUMAN; IMMUNOASSAY; KIDNEY TRANSPLANTATION; MALE; PRIORITY JOURNAL; SEROLOGY;

ALLELES; ANTIBODIES; BASE SEQUENCE; CROSS REACTIONS; FEMALE; HLA-DP ANTIGENS; HUMANS; MALE; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; TRANSPLANTATION IMMUNOLOGY;

EID: 84856334125     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2011.11.006     Document Type: Article

References (14)

1. Shaw S., Johnson A.H., Shearer G.M. Evidence for a new segregant series of B cell antigens that are encoded in the HLA-D region and that stimulate secondary allogenic proliferative and cytotoxic responses. J Exp Med 1980, 152:565-580.
2. Shaw S., DeMars R., Schlossman S.F., Smith P.L., Lampson L.A., Nadler L.M. Serologic identification of the human secondary B cell antigens. Correlations between function, genetics, and structure. J Exp Med 1982, 156:731-743.
3. Youngs D. HLA-DP alloantibodies. ASHI Q 2004, 28:60.
4. Goral S., Prak E.L., Kearns J., et al. Preformed donor-directed anti-HLA-DP antibodies may be an impediment to successful kidney transplantation. Nephrol Dial Transplant 2008, 23:390-392.
5. Tambur A.R., Buckingham M., McDonald L., Luo X. Development of donor-specific and non-donor-specific HLA-DP antibodies post-transplant: the role of epitope sharing and epitope matching. Clin Transpl 2006, 399-404.
6. Mucynski K.A., Ekle D.M., Coder D.M., Anderson S.K. Normal human kidney HLA-DR-expressing renal microvascular endothelial cells: characterization, isolation, and regulation of MHC class II expression. J Am Soc Nephrol 2003, 14:1336-1348.
7. Thaunat O., Hanf W., Dubois V., et al. Chronic humoral rejection mediated by anti-HLA-DP alloantibodies: insights into the role of epitope sharing in donor-specific and non-donor specific alloantibodies generation. Transpl Immunol 2009, 20:209-211.
8. Samaniego M., Mezrich J., Torrealba J., et al. C4d-positive acute antibody-mediated rejection due to anti-HLA-DP antibody: a tale of one patient and a review of the University of Wisconsin experience. Clin Transpl 2006, 503-507.
9. Singh P., Colombe B.W., Francos G.C., Martinez Cantarin M.P., Frank A.M. Acute humoral rejection in a zero mismatch deceased donor renal transplant due to an antibody to an HLA-DP alpha. Transplantation 2010, 90:220-221.
10. Qiu J., Cai J., Terasaki P.I., El-Awar N., Lee J.H. Detection of antibodies to HLA-DP in renal transplant recipients using single antigen beads. Transplantation 2005, 80:1511-1513.
11. Duquesnoy R.J., Awadalla Y., Lomago J., et al. Retransplant candidates have donor-specific antibodies that react with structurally defined HLA-DR, DQ, DP epitopes. Transpl Immunol 2008, 8:352-360.
12. Cano P., Fernandez-Vina M. Two sequence dimorphisms of DPB1 define the immunodominant serologic epitopes of HLA-DP. Hum Immunol 2009, 70:836-843.
13. Zachary A.A., Sholander J.T., Houp J.A., Leffell M.S. Using real data for a virtual crossmatch. Hum Immunol 2009, 70:574-579.
14. Piazza A., Poggi E., Ozzella G., et al. Anti-HLA-DP antibodies and graft failure in kidney transplantation. Transplantation 2006, 82:242.