Two sequence dimorphisms of DPB1 define the immunodominant serologic epitopes of HLA-DP

Human Immunology

Volumn 70, Issue 10, 2009, Pages 836-843

  Cano, Pedro ^a   Fernández Viña, Marcelo ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Antibodies; Antigens; HLA DP; Serology

Indexed keywords

EPITOPE; HLA ANTIGEN CLASS 2; HLA DPB1 ANTIGEN; HLA DR ANTIGEN;

AMINO ACID SEQUENCE; ARTICLE; BLOOD SAMPLING; CLUSTER ANALYSIS; EPITOPE MAPPING; HUMAN; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS;

ALLELES; AMINO ACID SEQUENCE; BASE SEQUENCE; CLUSTER ANALYSIS; HLA-DP ANTIGENS; HUMANS; IMMUNODOMINANT EPITOPES; ISOANTIBODIES; MOLECULAR SEQUENCE DATA; PROSPECTIVE STUDIES; SEQUENCE ALIGNMENT;

EID: 70349322397     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2009.07.011     Document Type: Article

References (13)

1. Vaidya S., Hilson B.M., Sheldon S., Cano P., and Fernández-Viña M. DP reactive antibody in a zero mismatch renal transplant pair. Hum Immunol 68 (2007) 947-949
2. Bodmer J., Bodmer W., Heyes J., So A., Tonks S., Trowsdale J., et al. Identification of HLA-DP polymorphism with DP alpha and DP beta probes and monoclonal antibodies: Correlation with primed lymphocyte typing. Proc Natl Acad Sci USA 84 (1987) 4596-4600
3. Klohe E., Pistillo M.P., Ferrara G.B., Goeken N.E., Graezel N.S., and Karr R.W. Critical role of HLA-DRB1 residue 58 in multiple polymorphic epitopes recognized by xonogenic and allogenic antibodies. Hum Immunol 35 (1992) 18-28
4. Colonna M., Tanigaki N., Tosi R., and Ferrara G.B. Serological detection and molecular localization of allelic HLA-DP supertypic epitopes. Eur J Immunol 19 (1989) 433-440
5. Tanigaki N., Tosi R., Parodi B., Sorrentino R., Ferrara G.B., and Strominger J.L. Detection of HLA-DP serological allodeterminants by the use of radioiodinated DP molecules. Eur J Immunol 17 (1987) 743-750
6. Mazzoleni O., Longo A., Angelini G., Colonna M., Tanigaki N., Delfino L., et al. Human monoclonal antibody MP8 detects a supertypic determinant encoded by DPB alleles DPB2.1, DPB3, DPB4.2, DPB8, DPB9, DPB10, and DPB14. Immunogenetics 30 (1989) 502-505
7. Goral S., Prak E.L., Kearns J., Bloom R.D., Pierce E., Dolyle A., et al. Preformed donor-directed anti-HLA-DP antibodies may be an impediment to successful kidney transplantation. Nephrol Dial Transplant 23 (2008) 390-392
8. Arnold M.L., Pei R., Spriewald B., and Wassmuth R. Anti-HLA class II antibodies in kidney transplant patients. Tissue Antigens 65 (2005) 370-378
9. Charron D.J., Lotteau V., and Turmel P. Hybrid HLA-DC antigens provide molecular evidence for gene trans-complementation. Nature 312 (1984) 157-159
10. Begovich A.B., Moonsamy P.V., Mack S.J., Barcellos L.F., Steiner L.L., Grams S., et al. Genetic variability and linkage disequilibrium within the HLA-DP region: Analysis of 15 different populations [published erratum in Tissue Antigens 2001;58:431]. Tissue Antigens 57 (2001) 424-439
11. Flomenberg N., Baxter-Lowe L.A., Confer D., Fernandez-Vina M., Filipovich A., Horowitz M., et al. Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome. Blood 104 (2004) 1923-1930
12. Neppert J., Nunez G., and Stastny P. HLA-A, B, C; -DR; -MT, -MB, and SB antigens on unstimulated human endothelial cells. Tissue Antigens 24 (1984) 40-47
13. Nuñez G., Giles R.C., Ball E.J., Hurley C.K., Capra J.D., and Stastny P. Expression of HLA-DR, MB, MT and SB antigens on human mononuclear cells: Identification of two phenotypically distinct monocyte populations. J Immunol 133 (1984) 1300-1306