Topical androgen antagonism promotes cutaneous wound healing without systemic androgen deprivation by blocking β-catenin nuclear translocation and cross-talk with TGF-β signaling in keratinocytes

Wound Repair and Regeneration

Volumn 20, Issue 1, 2012, Pages 61-73

  Toraldo, Gianluca ^a   Bhasin, Shalender ^a   Bakhit, Mena ^a   Guo, Wen ^a   Serra, Carlo ^a   Safer, Joshua D ^a   Bhawan, Jag ^a   Jasuja, Ravi ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; FLUTAMIDE; LUCIFERASE; TESTOSTERONE; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

ANDROGEN DEPRIVATION THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; C57BL 6 MOUSE; CELL MIGRATION; CONTROLLED STUDY; DATA ANALYSIS; EPITHELIZATION; GENE TRANSLOCATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HYPOTHESIS; IN VIVO STUDY; INTRACELLULAR SIGNALING; KERATINOCYTE; MALE; MEDICAL RECORD; MOLECULAR INTERACTION; MOUSE; NONHUMAN; ORCHIECTOMY; PRIORITY JOURNAL; REPORTER GENE; SIGNAL TRANSDUCTION; SKIN INJURY; WOUND CLOSURE; WOUND CONTRACTION; WOUND HEALING;

ADMINISTRATION, CUTANEOUS; ANDROGEN ANTAGONISTS; ANIMALS; BETA CATENIN; FLUTAMIDE; KERATINOCYTES; MICE; MICE, INBRED C57BL; RECEPTOR CROSS-TALK; SIGNAL TRANSDUCTION; SKIN; TRANSFORMING GROWTH FACTOR BETA1; TRANSLOCATION, GENETIC; WOUND HEALING;

EID: 84856331322     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/j.1524-475X.2011.00757.x     Document Type: Article

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