5α-Dihydrotestosterone (DHT) retards wound closure by inhibiting re-epithelialization

Journal of Pathology

Volumn 217, Issue 1, 2009, Pages 73-82

  Gilliver, S C ^a   Ruckshanthi, J P D ^a   Hardman, M J ^a   Zeef, L A H ^a   Ashcroft, G S ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

5 dihydrotestosterone (dht); Healing; Keratinocytes; Mice; Migration; Re epithelialization; Skin; Wounds

Indexed keywords

ANDROSTANOLONE; BETA CATENIN; STEROID 5ALPHA REDUCTASE; ANDROGEN; CATNB PROTEIN, RAT; DRUG DERIVATIVE; ENZYME INHIBITOR; FINASTERIDE; MK 0434; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG INHIBITION; EPITHELIZATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WOUND CLOSURE; WOUND CONTRACTION; WOUND HEALING; ANIMAL; CELL CULTURE; CELL MOTION; DRUG ANTAGONISM; DRUG EFFECT; EPIDERMIS; EPITHELIUM; INJURY; KERATINOCYTE; METABOLISM; PHYSIOLOGY; SKIN; SPRAGUE DAWLEY RAT;

ANDROGENS; ANIMALS; BETA CATENIN; CELL MOVEMENT; CELLS, CULTURED; DIHYDROTESTOSTERONE; ENZYME INHIBITORS; EPIDERMIS; EPITHELIUM; FINASTERIDE; KERATINOCYTES; MALE; RATS; RATS, SPRAGUE-DAWLEY; SKIN; TESTOSTERONE 5-ALPHA-REDUCTASE; WOUND HEALING;

EID: 58449122733     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2444     Document Type: Article

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