Morphometric analysis of centrosome position in tissues

Methods in Molecular Biology

Volumn 839, Issue , 2012, Pages 249-255

  Happé, Hester ^a   De Heer, Emile ^a   Peters, Dorien J M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Centrosome position; Cilium; Immuno fluorescence; Morphometric analysis; Planar cell polarity

Indexed keywords

ANIMAL; ARTICLE; CELL POLARITY; CENTROSOME; CYTOLOGY; EPITHELIUM CELL; FLUORESCENCE MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; KIDNEY TUBULE; METABOLISM;

ANIMALS; CELL POLARITY; CENTROSOME; EPITHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; KIDNEY TUBULES; MICROSCOPY, FLUORESCENCE;

EID: 84856327841     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-510-7_20     Document Type: Article

References (5)

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2. Patel V, Li L, Cobo-Stark P, Shao X, Somlo S, Lin F, Igarashi P (2008) Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia. Hum Mol Genet 17 :1578-1590. (Pubitemid 351737162)
3. Saburi S, Hester I, Fischer E, Pontoglio M, Eremina V, Gessler M, Quaggin SE, Harrison R, Mount R, McNeill H (2008) Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nat Genet 40 :1010-1015.
4. Happe H, Leonhard WN, Van der Wal A, Van de Water B, Lantinga van Leeuwen IS, Breuning MH, De Heer E, Peters DJ (2009) Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways. Hum Mol Genet 18 :2532-2542.
5. Jonassen JA, San Agustin J, Follit JA, Pazour GJ (2008) Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease. J Cell Biol 183 :377-384.