Vitamin D and autoimmunity. First part: Fundamental aspects;Vitamine D et auto-immunité. Première partie: Aspects fondamentaux

Revue de Medecine Interne

Volumn 33, Issue 2, 2012, Pages 80-86

  Schoindre, Y ^a   Terrier, B ^b   Kahn, J E ^a   Saadoun, D ^b   Souberbielle, J C ^c   Benveniste, O ^b   Amoura, Z ^b   Piette, J C ^b   Cacoub, P ^b   Costedoat Chalumeau, N ^b  

^a LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Autoimmune diseases; Autophagy; B cells; Dendritic cells; Regulatory T cells; T cells; Vitamin D

Indexed keywords

POLYPEPTIDE ANTIBIOTIC AGENT; VITAMIN D;

AUTOIMMUNITY; AUTOPHAGY; B LYMPHOCYTE; INFLAMMATION; MYELOID DENDRITIC CELL; PEPTIDE SYNTHESIS; SHORT SURVEY; T LYMPHOCYTE;

ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; AUTOIMMUNE DISEASES; AUTOIMMUNITY; B-LYMPHOCYTES; BONE AND BONES; CALCIUM; DENDRITIC CELLS; HOMEOSTASIS; HUMANS; T-LYMPHOCYTES; TREATMENT OUTCOME; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84856326569     PISSN: 02488663     EISSN: 17683122     Source Type: Journal    
DOI: 10.1016/j.revmed.2011.11.009     Document Type: Short Survey

References (42)

1. Arnson Y., Amital H., Shoenfeld Y. Vitamin D and autoimmunity: new aetiological and therapeutic considerations. Ann Rheum Dis 2007, 66:1137-1142.
2. Bouillon R., Carmeliet G., Verlinden L., van Etten E., Verstuyf A., Luderer H.F., et al. Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev 2008, 29:726-776.
3. Holick M.F. Vitamin D deficiency. N Engl J Med 2007, 357:266-281.
4. Zhou C., Assem M., Tay J.C., Watkins P.B., Blumberg B., Schuetz E.G., et al. Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24expression and drug-induced osteomalacia. J Clin Invest 2006, 116:1703-1712.
5. Cannell J.J., Zasloff M., Garland C.F., Scragg R., Giovannucci E. On the epidemiology of influenza. Virol J 2008, 5:29.
6. Souberbielle J.C., Friedlander G., Kahan A., Cormier C. Evaluating vitamin D status. Implications for preventing and managing osteoporosis and other chronic diseases. Joint Bone Spine 2006, 73:249-253.
7. Smolders J., Damoiseaux J., Menheere P., Tervaert J.W., Hupperts R. Fok-I vitamin D receptor gene polymorphism (rs10735810) and vitamin D metabolism in multiple sclerosis. J Neuroimmunol 2009, 207:117-121.
8. Wang T.J., Zhang F., Richards J.B., Kestenbaum B., van Meurs J.B., Berry D., et al. Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet 2010, 376(9736):180-188.
9. Mithal A., Wahl D.A., Bonjour J.P., Burckhardt P., Dawson-Hughes B., Eisman J.A., et al. Global vitamin D status and determinants of hypovitaminosis D. Osteoporos Int 2009, 20:1807-1820.
10. Hagenau T., Vest R., Gissel T.N., Poulsen C.S., Erlandsen M., Mosekilde L., et al. Global vitamin D levels in relation to age, gender, skin pigmentation and latitude: an ecologic meta-regression analysis. Osteoporos Int 2009, 20:133-140.
11. Holick M.F., Siris E.S., Binkley N., Beard M.K., Khan A., Katzer J.T., et al. Prevalence of Vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy. J Clin Endocrinol Metab 2005, 90:3215-3224.
12. Mora J.R., Iwata M., von Andrian U.H. Vitamin effects on the immune system: vitamins A and D take centre stage. Nat Rev Immunol 2008, 8(9):685-698.
13. Adorini L., Penna G. Induction of tolerogenic dendritic cells by vitamin D receptor agonists. Handb Exp Pharmacol 2009, 251-273.
14. Unger W.W., Laban S., Kleijwegt F.S., van der Slik A.R., Roep B.O. Induction of Treg by monocyte-derived DC modulated by vitamin D3or dexamethasone: differential role for PD-L1. Eur J Immunol 2009, 39:3147-3159.
15. Szeles L., Keresztes G., Torocsik D., Balajthy Z., Krenacs L., Poliska S., et al. 1,25-dihydroxyvitamin D3is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype. J Immunol 2009, 182:2074-2083.
16. Enioutina E.Y., Bareyan D., Daynes R.A. TLR ligands that stimulate the metabolism of vitamin D3in activated murine dendritic cells can function as effective mucosal adjuvants to subcutaneously administered vaccines. Vaccine 2008, 26:601-613.
17. Penna G., Roncari A., Amuchastegui S., Daniel K.C., Berti E., Colonna M., et al. Expression of the inhibitory receptor ILT3on dendritic cells is dispensable for induction of CD4+Foxp3+ regulatory T-cells by 1,25-dihydroxyvitamin D3. Blood 2005, 106:3490-3497.
18. van Halteren A.G., van Etten E., de Jong E.C., Bouillon R., Roep B.O., Mathieu C. Redirection of human autoreactive T-cells Upon interaction with dendritic cells modulated by TX527, an analog of 1,25dihydroxyvitamin D(3). Diabetes 2002, 51:2119-2125.
19. van Halteren A.G., Tysma O.M., van Etten E., Mathieu C., Roep B.O. 1alpha, 25-dihydroxyvitamin D3or analogue treated dendritic cells modulate human autoreactive T-cells via the selective induction of apoptosis. J Autoimmun 2004, 23:233-239.
20. Zanoni I., Granucci F. The regulatory role of dendritic cells in the induction and maintenance of T-cell tolerance. Autoimmunity 2011, 44:23-32.
21. Israni N., Goswami R., Kumar A., Rani R. Interaction of vitamin D receptor with HLA DRB1*0301in type 1diabetes patients from North India. PLoS One 2009, 4:e8023.
22. Ramagopalan S.V., Maugeri N.J., Handunnetthi L., Lincoln M.R., Orton S.M., Dyment D.A., et al. Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501is regulated by vitamin D. PLoS Genet 2009, 5:e1000369.
23. Rahman A., Isenberg D.A. Systemic lupus erythematosus. N Engl J Med 2008, 358:929-939.
24. Meyer O. Lupus érythémateux systémique. Traité des maladies et syndromes systémiques 2008, 123-299. ed: Médecine-Sciences Flammarion. 5e édition. L. Guillevin, O. Meyer, J. Sibilia (Eds.).
25. Wing K., Sakaguchi S. Regulatory T-cells exert checks and balances on self tolerance and autoimmunity. Nat Immunol 2010, 11:7-13.
26. Buckner J.H. Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T-cells in human autoimmune diseases. Nat Rev Immunol 2010, 10:849-859.
27. Baeke F., Korf H., Overbergh L., Verstuyf A., Thorrez L., Van Lommel L., et al. The vitamin D analog, TX527, promotes a human CD4+CD25high CD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation. J Immunol 2011, 186:132-142.
28. Jeffery L.E., Burke F., Mura M., Zheng Y., Qureshi O.S., Hewison M., et al. 1,25-Dihydroxyvitamin D3and IL-2combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T-cells expressing CTLA-4and FoxP3. J Immunol 2009, 183:5458-5467.
29. Cippitelli M., Santoni A. Vitamin D3: a transcriptional modulator of the interferon-gamma gene. Eur J Immunol 1998, 28:3017-3030.
30. Smolders J., Thewissen M., Peelen E., Menheere P., Tervaert J.W., Damoiseaux J., et al. Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis. PLoS One 2009, 4:e6635.
31. Smolders J., Menheere P., Thewissen M., Peelen E., Tervaert J.W., Hupperts R., et al. Regulatory T cell function correlates with serum 25-hydroxyvitamin D, but not with 1,25-dihydroxyvitamin D, parathyroid hormone and calcium levels in patients with relapsing remitting multiple sclerosis. J Steroid Biochem Mol Biol 2010, 121:243-246.
32. Chen S., Sims G.P., Chen X.X., Gu Y.Y., Lipsky P.E. Modulatory effects of 1,25-dihydroxyvitamin D3on human B cell differentiation. J Immunol 2007, 179:1634-1647.
33. Heine G., Niesner U., Chang H.D., Steinmeyer A., Zugel U., Zuberbier T., et al. 1,25-dihydroxyvitamin D(3) promotes IL-10production in human B cells. Eur J Immunol 2008, 38:2210-2218.
34. Linker-Israeli M., Elstner E., Klinenberg J.R., Wallace D.J., Koeffler H.P. Vitamin D(3) and its synthetic analogs inhibit the spontaneous in vitro immunoglobulin production by SLE-derived PBMC. Clin Immunol 2001, 99:82-93.
35. Coulombe F., Behr M.A. Crohn's disease as an immune deficiency?. Lancet 2009, 374:769-770.
36. Fritz T., Niederreiter L., Adolph T., Blumberg R.S., Kaser A. Crohn's disease: NOD2, autophagy and ER stress converge. Gut 2011, 60(11):1580-1588.
37. Cooney R., Baker J., Brain O., Danis B., Pichulik T., Allan P., et al. NOD2stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med 2010, 16:90-97.
38. Jéru I., Amsellem S. Inflammasome et interleukine 1. Rev Med Interne 2011, 32:218-224.
39. Travassos L.H., Carneiro L.A., Ramjeet M., Hussey S., Kim Y.G., Magalhaes J.G., et al. Nod1and Nod2direct autophagy by recruiting ATG16L1to the plasma membrane at the site of bacterial entry. Nat Immunol 2010, 11:55-62.
40. Levine B., Mizushima N., Virgin H.W. Autophagy in immunity and inflammation. Nature 2011, 469:323-335.
41. Wang T.T., Dabbas B., Laperriere D., Bitton A.J., Soualhine H., Tavera-Mendoza L.E., et al. Direct and indirect induction by 1,25-dihydroxyvitamin D3of the NOD2/CARD15-defensin beta2innate immune pathway defective in Crohn disease. J Biol Chem 2010, 285:2227-2231.
42. Verway M., Behr M.A., White J.H. Vitamin D, NOD2, autophagy and Crohn's disease. Expert Rev Clin Immunol 2010, 6:505-508.