Radical radiotherapy for nasopharyngeal carcinoma in elderly patients: The importance of co-morbidity assessment

Oral Oncology

Volumn 48, Issue 2, 2012, Pages 162-167

  Sze, Henry C K ^a   Ng, W T ^a   Chan, Oscar S H ^a   Shum, Tracy C Y ^a   Chan, Lucy L K ^a   Lee, Anne W M ^a  

^a PAMELA YOUDE NETHERSOLE EASTERN HOSPITAL   (Hong Kong)

Author keywords

ACE 27; Co morbidity; Elderly; Nasopharyngeal carcinoma; Prognosis; Radiotherapy

Indexed keywords

CISPLATIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER MORTALITY; CANCER PATIENT; CANCER RADIOTHERAPY; COMORBIDITY; CONTROLLED STUDY; DISTANT METASTASIS; FAILURE FREE SURVIVAL; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NASOPHARYNX CARCINOMA; OVERALL SURVIVAL; PATIENT SELECTION; PERFORMANCE; PRIORITY JOURNAL; PROGNOSIS; RADIATION DOSE; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; COMORBIDITY; FEMALE; HUMANS; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; PATIENT SELECTION; PROGNOSIS; RADIOTHERAPY DOSAGE; RADIOTHERAPY, CONFORMAL; RISK ASSESSMENT; RISK FACTORS; SURVIVAL RATE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84856325946     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2011.08.019     Document Type: Article

References (32)

1. A.W. Lee, W.M. Sze, and J.S. Au Treatment results for nasopharyngeal carcinoma in the modern era: the Hong Kong experience Int J Radiat Oncol Biol Phys 61 2005 1107 1116 (Pubitemid 40340904)
2. J.F. Piccirillo Importance of comorbidity in head and neck cancer Laryngoscope 110 2000 593 602 (Pubitemid 30198711)
3. J.F. Piccirillo, R.M. Tierney, I. Costas, L. Grove, and E.L. Spitznagel Jr. Prognostic importance of comorbidity in a hospital-based cancer registry JAMA 291 2004 2441 2447 (Pubitemid 38669187)
4. S.N. Rogers, A. Aziz, D. Lowe, and D.J. Husband Feasibility study of the retrospective use of the Adult Comorbidity Evaluation index (ACE-27) in patients with cancer of the head and neck who had radiotherapy Br J Oral Maxillofac Surg 44 2006 283 288 (Pubitemid 43923719)
5. V. Paleri, R.G. Wight, and G.R. Davies Impact of comorbidity on the outcome of laryngeal squamous cancer Head Neck 25 2003 1019 1026 (Pubitemid 37475264)
6. B. Singh, P.G. Cordeiro, E. Santamaria, A.R. Shaha, D.G. Pfister, and J.P. Shah Factors associated with complications in microvascular reconstruction of head and neck defects Plast Reconstr Surg 103 1999 403 411 (Pubitemid 29071552)
7. P.A. Borggreven, D.J. Kuik, J.J. Quak, R. de Bree, G.B. Snow, and C.R. Leemans Comorbid condition as a prognostic factor for complications in major surgery of the oral cavity and oropharynx with microvascular soft tissue reconstruction Head Neck 25 2003 808 815 (Pubitemid 37139893)
8. S.H. Kagan, A.A. Chalian, and A.N. Goldberg Impact of age on clinical care pathway length of stay after complex head and neck resection Head Neck 24 2002 545 548 [discussion 545] (Pubitemid 34568555)
9. I. Fleming, J. Cooper, and D. Henson AJCC cancer staging handbook 1997 Lippincott-Raven New York
10. W.T. Ng, S.H. Chan, and A.W. Lee Parapharyngeal extension of nasopharyngeal carcinoma: still a significant factor in era of modern radiotherapy? Int J Radiat Oncol Biol Phys 72 2008 1082 1089
11. M.A. Frable, N. El-Roman, A. Lenis, and J.P. Hung Hemorrhagic complications of facial fractures Laryngoscope 84 1974 2051 2057
12. A.W. Lee, W.H. Lau, and S.Y. Tung Preliminary results of a randomized study on therapeutic gain by concurrent chemotherapy for regionally-advanced nasopharyngeal carcinoma: NPC-9901 Trial by the Hong Kong Nasopharyngeal Cancer Study Group J Clin Oncol 23 2005 6966 6975
13. T.K. Yau, A.W. Lee, and D.H. Wong Treatment of Stage IV(A-B) nasopharyngeal carcinoma by induction-concurrent chemoradiotherapy and accelerated fractionation: impact of chemotherapy schemes Int J Radiat Oncol Biol Phys 66 2006 1004 1010 (Pubitemid 44633506)
14. T.K. Yau, A.W. Lee, and D.H. Wong Induction chemotherapy with cisplatin and gemcitabine followed by accelerated radiotherapy and concurrent cisplatin in patients with stage IV(A-B) nasopharyngeal carcinoma Head Neck 28 2006 880 887 (Pubitemid 44497863)
15. A.W. Lee, S.Y. Tung, and A.T. Chan Preliminary results of a randomized study (NPC-9902 Trial) on therapeutic gain by concurrent chemotherapy and/or accelerated fractionation for locally advanced nasopharyngeal carcinoma Int J Radiat Oncol Biol Phys 66 2006 142 151 (Pubitemid 44175659)
16. M.H. Kaplan, and A.R. Feinstein The importance of classifying initial co-morbidity in evaluatin the outcome of diabetes mellitus J Chronic Dis 27 1974 387 404
17. J.P. Pignon, A. le Maitre, and J. Bourhis Meta-analyses of chemotherapy in head and neck cancer (MACH-NC): an update Int J Radiat Oncol Biol Phys 69 2007 S112 114
18. P. Olmi, G. Ausili-Cefaro, and L. Loreggian Radiation therapy in the elderly with head and neck cancer Rays 22 1997 77 81 (Pubitemid 27288064)
19. T. Pignon, J.C. Horiot, W. Van den Bogaert, M. Van Glabbeke, and P. Scalliet No age limit for radical radiotherapy in head and neck tumours Eur J Cancer 32A 1996 2075 2081 (Pubitemid 26419456)
20. A.S. Allal, D. Maire, M. Becker, and P. Dulguerov Feasibility and early results of accelerated radiotherapy for head and neck carcinoma in the elderly Cancer 88 2000 648 652 (Pubitemid 30056942)
21. S.H. Huang, B. O'Sullivan, and J. Waldron Patterns of care in elderly head-and-neck cancer radiation oncology patients: a single-center cohort study Int J Radiat Oncol Biol Phys 79 2011 46 51
22. A.W. Lee, S.Y. Tung, and A.T. Chan A randomized trial on addition of concurrent-adjuvant chemotherapy and/or accelerated fractionation for locally-advanced nasopharyngeal carcinoma Radiother Oncol 98 2011 15 22
23. A.W. Lee, S.Y. Tung, and D.T. Chua Randomized trial of radiotherapy plus concurrent-adjuvant chemotherapy vs radiotherapy alone for regionally advanced nasopharyngeal carcinoma J Natl Cancer Inst 102 2010 1188 1198
24. D. Rades, F. Fehlauer, J. Wroblesky, D. Albers, S.E. Schild, and R. Schmidt Prognostic factors in head-and-neck cancer patients treated with surgery followed by intensity-modulated radiotherapy (IMRT), 3D-conformal radiotherapy, or conventional radiotherapy Oral Oncol 43 2007 535 543 (Pubitemid 46860347)
25. J.L. Yi, L. Gao, and X.D. Huang Nasopharyngeal carcinoma treated by radical radiotherapy alone: ten-year experience of a single institution Int J Radiat Oncol Biol Phys 65 2006 161 168
26. D.B. Reuben Geriatric assessment in oncology Cancer 80 1997 1311 1316 (Pubitemid 27407234)
27. M.E. Charlson, P. Pompei, K.L. Ales, and C.R. MacKenzie A new method of classifying prognostic comorbidity in longitudinal studies: development and validation J Chronic Dis 40 1987 373 383 (Pubitemid 17055592)
28. M.D. Miller, C.F. Paradis, and P.R. Houck Rating chronic medical illness burden in geropsychiatric practice and research: application of the Cumulative Illness Rating Scale Psychiatry Res 41 1992 237 248
29. V. Paleri, R.G. Wight, and C.E. Silver Comorbidity in head and neck cancer: a critical appraisal and recommendations for practice Oral Oncol 46 2010 712 719
30. Y. Ramakrishnan, V. Paleri, R. Shah, I.N. Steen, R.G. Wight, and C.G. Kelly Comorbidity in nasopharyngeal carcinoma: a preliminary communication on the prevalence, descriptive distribution and impact on outcome Clin Otolaryngol 32 2007 484 488 (Pubitemid 350222091)
31. E. Vaccher, R. Talamini, G. Franchin, U. Tirelli, and L. Barzan Elderly head and neck (H-N) cancer patients: a monoinstitutional series Tumori 88 2002 S63 66
32. N. Bhattacharyya A matched survival analysis for squamous cell carcinoma of the head and neck in the elderly Laryngoscope 113 2003 368 372 (Pubitemid 36177009)