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Volumn 13, Issue 3, 2012, Pages 345-355

Improving treatment adherence to antihypertensive therapy: The role of single-pill combinations

Author keywords

Adherence; Antihypertensives; Compliance; Hypertension control; Persistence; Single pill combination therapy

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; THIAZIDE DIURETIC AGENT;

EID: 84856287359     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1517/14656566.2012.652086     Document Type: Review
Times cited : (22)

References (71)
  • 1
    • 33845338724 scopus 로고    scopus 로고
    • Projections of global mortality and burden of disease from 2002 to 2030
    • Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 2006;13:e442
    • (2006) PLoS Med , vol.13
    • Mathers, C.D.1    Loncar, D.2
  • 3
    • 0242654867 scopus 로고    scopus 로고
    • Effects of different blood-pressure-lowering regimens on major cardiovascular events: Results of prospectively-designed overviews of randomised trials
    • Blood Pressure Lowering Treatment Trialists Collaboration
    • Blood Pressure Lowering Treatment Trialists Collaboration. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. Lancet 2003;362:1527-35
    • (2003) Lancet , vol.362 , pp. 1527-1535
  • 4
    • 77952750659 scopus 로고    scopus 로고
    • US trends in prevalence, awareness, treatment, and control of hypertension 1988 - 2008
    • Egan BM, Zhao Y, Axon RN. US trends in prevalence, awareness, treatment, and control of hypertension 1988 - 2008. JAMA 2010;303:2043-50.
    • (2010) JAMA , vol.303 , pp. 2043-2050
    • Egan, B.M.1    Zhao, Y.2    Axon, R.N.3
  • 5
    • 58549115507 scopus 로고    scopus 로고
    • Hypertension awareness, treatment and control - Continued disparities in adults: United States, 2005 - 2006
    • Ostchega Y, Yoon SS, Hughes J, Louis T. Hypertension awareness, treatment and control - continued disparities in adults: United States, 2005 - 2006. NCHS Data Brief 2008;3:1-8
    • (2008) NCHS Data Brief , vol.3 , pp. 1-8
    • Ostchega, Y.1    Yoon, S.S.2    Hughes, J.3    Louis, T.4
  • 6
    • 33847633400 scopus 로고    scopus 로고
    • Prevalence, awareness, treatment, and control of hypertension among United States adults 1999-2004
    • DOI 10.1161/01.HYP.0000252676.46043.18, PII 0000426820070100000018
    • Ong KL, Cheung BMY, Man BY, et al. Pravalence, awareness, treatment, and control of hypertension among United States adults 1999 - 2004. Hypertension 2007;49:69-75 (Pubitemid 46360343)
    • (2007) Hypertension , vol.49 , Issue.1 , pp. 69-75
    • Ong, K.L.1    Cheung, B.M.Y.2    Man, Y.B.3    Lau, C.P.4    Lam, K.S.L.5
  • 7
    • 61849116330 scopus 로고    scopus 로고
    • Cardiovascular prevention guidelines in daily practice: A comparison of EUROASPIRE I, II, and III surveys in eight European countries
    • Kotseva K, Wood D, De Backer G, et al. Cardiovascular prevention guidelines in daily practice: a comparison of EUROASPIRE I, II, and III surveys in eight European countries. Lancet 2009;373:929-40
    • (2009) Lancet , vol.373 , pp. 929-940
    • Kotseva, K.1    Wood, D.2    De Backer, G.3
  • 8
    • 70350246278 scopus 로고    scopus 로고
    • Adherence to antihypertensive medications and cardiovascular morbidity among newly diagnosed hypertensive patients
    • Mazzaglia G, Ambrosioni E, Alacqua M, et al. Adherence to antihypertensive medications and cardiovascular morbidity among newly diagnosed hypertensive patients. Circulation 2009;120:1598-605
    • (2009) Circulation , vol.120 , pp. 1598-1605
    • Mazzaglia, G.1    Ambrosioni, E.2    Alacqua, M.3
  • 9
    • 77951621416 scopus 로고    scopus 로고
    • Impact of adherence to antihypertensive agents on clinical outcomes and hospitalization costs
    • Dragomir A, Cote R, Roy L, et al. Impact of adherence to antihypertensive agents on clinical outcomes and hospitalization costs. Med Care 2010;48:418-25
    • (2010) Med Care , vol.48 , pp. 418-425
    • Dragomir, A.1    Cote, R.2    Roy, L.3
  • 10
    • 67650651982 scopus 로고    scopus 로고
    • Improving outcomes in hypertensive patients: Focus on adherence and persistence with antihypertensive therapy
    • Elliott WJ. Improving outcomes in hypertensive patients: focus on adherence and persistence with antihypertensive therapy. J Clin Hypertens (Greenwich) 2009;11:376-82
    • (2009) J Clin Hypertens (Greenwich) , vol.11 , pp. 376-382
    • Elliott, W.J.1
  • 11
    • 77949347711 scopus 로고    scopus 로고
    • Compliance with the treatment of hypertension: The potential of combination therapy
    • Erdine S. Compliance with the treatment of hypertension: the potential of combination therapy. J Clin Hypertens (Greenwich) 2010;12:40-6
    • (2010) J Clin Hypertens (Greenwich) , vol.12 , pp. 40-46
    • Erdine, S.1
  • 12
    • 34547666983 scopus 로고    scopus 로고
    • Hypertension treatment in a medicare population: Adherence and systolic blood pressure control
    • DOI 10.1016/j.clinthera.2007.05.010, PII S0149291807001397
    • Fung V, Huang J, Brand R, et al. Hypertension treatment in a medicare population: adherence and systolic blood pressure control. Clin Ther 2007;29:972-84 (Pubitemid 47223429)
    • (2007) Clinical Therapeutics , vol.29 , Issue.5 , pp. 972-984
    • Fung, V.1    Huang, J.2    Brand, R.3    Newhouse, J.P.4    Hsu, J.5
  • 13
    • 77949562278 scopus 로고    scopus 로고
    • Intensive multifactorial intervention for stable coronary artery disease: Optimal medical therapy in the COURAGE (clinical outcomes utilizing revascularization and aggressive drug evaluation) trial
    • COURAGE Trial Research Group
    • Maron DJ, Boden WE, O'Rourke RA, et al. COURAGE Trial Research Group. Intensive multifactorial intervention for stable coronary artery disease: optimal medical therapy in the COURAGE (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation) trial. J Am Coll Cardiol 2010;55:1348-58
    • (2010) J Am Coll Cardiol , vol.55 , pp. 1348-1358
    • Maron, D.J.1    Boden, W.E.2    O'rourke, R.A.3
  • 14
    • 69249190363 scopus 로고    scopus 로고
    • Association between prescription burden and medication adherence in patients initiating antihypertensive and lipid-lowering therapy
    • Benner JS, Chapman RH, Petrilla AA, et al. Association between prescription burden and medication adherence in patients initiating antihypertensive and lipid-lowering therapy. Am J Health Syst Pharm 2009;66:1471-7
    • (2009) Am J Health Syst Pharm , vol.66 , pp. 1471-1477
    • Benner, J.S.1    Chapman, R.H.2    Petrilla, A.A.3
  • 15
    • 1842681515 scopus 로고    scopus 로고
    • How can we improve adherence to blood pressure-lowering medication in ambulatory care? Systematic review of randomized controlled trials
    • DOI 10.1001/archinte.164.7.722
    • Schroeder K, Fahey T, Ebrahim S. How can we improve adherence to blood pressure-lowering medication in ambulatory care? Systematic review of randomised controlled trials. Arch Intern Med 2004;164:722-32 (Pubitemid 38478694)
    • (2004) Archives of Internal Medicine , vol.164 , Issue.7 , pp. 722-732
    • Schroeder, K.1    Fahey, T.2    Ebrahim, S.3
  • 16
    • 68049100196 scopus 로고    scopus 로고
    • Interventions to improve medication adherence among older adults: Meta-analysis of adherence outcomes among randomised controlled trials
    • Conn VS, Hafdahl AR, Cooper PS, et al. Interventions to improve medication adherence among older adults: meta-analysis of adherence outcomes among randomised controlled trials. Gerontologist 2009;49:447-62
    • (2009) Gerontologist , vol.49 , pp. 447-462
    • Conn, V.S.1    Hafdahl, A.R.2    Cooper, P.S.3
  • 17
    • 64849106873 scopus 로고    scopus 로고
    • A simplified approach to the treatment of uncomplicated hypertension: A cluster randomized, controlled trial
    • Feldman RD, Zou GY, Vandervoort MK, et al. A simplified approach to the treatment of uncomplicated hypertension: a cluster randomized, controlled trial. Hypertension 2009;53:646-53
    • (2009) Hypertension , vol.53 , pp. 646-653
    • Feldman, R.D.1    Zou, G.Y.2    Vandervoort, M.K.3
  • 18
    • 34547615709 scopus 로고    scopus 로고
    • 2007 Guidelines for the management of arterial hypertension: The task force for the management of arterial hypertension of the European society of hypertension (ESH) and of the European society of cardiology (ESC)
    • for The task force for the management of arterial hypertension of the European Society of Hypertension, The task force for the management of arterial hypertension of the European Society of Cardiology
    • Mancia G, De Backer G, Dominiczak A, et al. for The task force for the management of arterial hypertension of the European Society of Hypertension, The task force for the management of arterial hypertension of the European Society of Cardiology. 2007 Guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 2007;28:1462-536
    • (2007) Eur Heart J , vol.28 , pp. 1462-1536
    • Mancia, G.1    De Backer, G.2    Dominiczak, A.3
  • 19
    • 34548166766 scopus 로고    scopus 로고
    • Renin: Friend or foe?
    • DOI 10.1136/hrt.2006.107706
    • Brown MJ. Renin: friend or foe? Heart 2007;93:1026-33 (Pubitemid 47310975)
    • (2007) Heart , vol.93 , Issue.9 , pp. 1026-1033
    • Brown, M.J.1
  • 20
    • 74549183897 scopus 로고    scopus 로고
    • Angiotensin receptor blockers: Baseline therapy in hypertension?
    • Messerli FH, Bangalore S, Ruschitzka F. Angiotensin receptor blockers: baseline therapy in hypertension? Eur Heart J 2009;30:2427-30
    • (2009) Eur Heart J , vol.30 , pp. 2427-2430
    • Messerli, F.H.1    Bangalore, S.2    Ruschitzka, F.3
  • 22
    • 76149089578 scopus 로고    scopus 로고
    • Role of angiotensin-converting enzyme inhibitors in vascular modulation: Beyond the hypertensive effects
    • Katragadda S, Arora RR. Role of angiotensin-converting enzyme inhibitors in vascular modulation: beyond the hypertensive effects. Am J Ther 2010;17:e11-23
    • (2010) Am J Ther , vol.17
    • Katragadda, S.1    Arora, R.R.2
  • 23
    • 77951085291 scopus 로고    scopus 로고
    • Evidence for the efficacy of ARBs across the cardiovascular continuum
    • Gupta M, Honos GN, Velazquez EJ, et al. Evidence for the efficacy of ARBs across the cardiovascular continuum. Curr Med Res Opin 2010;26:1203-18.
    • (2010) Curr Med Res Opin , vol.26 , pp. 1203-1218
    • Gupta, M.1    Honos, G.N.2    Velazquez, E.J.3
  • 24
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • Brenner BM, Cooper ME, de ZD, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001;345(12):861-9
    • (2001) N Engl J Med , vol.345 , Issue.12 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    De, Z.D.3
  • 25
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001;345(12):851-60
    • (2001) N Engl J Med , vol.345 , Issue.12 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3
  • 27
    • 0344373794 scopus 로고    scopus 로고
    • The antihypertensive and lipid-lowering treatment to prevent heart attack trial. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)
    • ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group
    • ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 2002;288:2981-97
    • (2002) JAMA , vol.288 , pp. 2981-2997
  • 28
    • 78650703447 scopus 로고    scopus 로고
    • Antihypertensive drugs and risk of cancer: Network meta-analyses and trial sequential analyses of 324,168 participants from randomised trials
    • Bangalore S, Kumar S, Kjeldsen SE, et al. Antihypertensive drugs and risk of cancer: network meta-analyses and trial sequential analyses of 324,168 participants from randomised trials. Lancet Oncol 2011;12:65-82
    • (2011) Lancet Oncol , vol.12 , pp. 65-82
    • Bangalore, S.1    Kumar, S.2    Kjeldsen, S.E.3
  • 29
    • 79952774764 scopus 로고    scopus 로고
    • Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138,769 individuals
    • Arb Trialists Collaboration
    • ARB Trialists Collaboration. Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138,769 individuals. J Hypertens 2011;29:623-35
    • (2011) J Hypertens , vol.29 , pp. 623-635
  • 30
    • 63049137529 scopus 로고    scopus 로고
    • Long-acting calcium antagonists in patients with coronary artery disease: A meta-analysis
    • Bangalore S, Parkar S, Messerli FH. Long-acting calcium antagonists in patients with coronary artery disease: a meta-analysis. Am J Med 2009;122:356-65
    • (2009) Am J Med , vol.122 , pp. 356-365
    • Bangalore, S.1    Parkar, S.2    Messerli, F.H.3
  • 31
    • 53949086528 scopus 로고    scopus 로고
    • Relation of beta-blocker-induced heart rate lowering and cardioprotection in hypertension
    • Bangalore S, Sawhney S, Messerli FH. Relation of beta-blocker-induced heart rate lowering and cardioprotection in hypertension. J Am Coll Cardiol 2008;52:1482-9
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1482-1489
    • Bangalore, S.1    Sawhney, S.2    Messerli, F.H.3
  • 32
    • 51449099674 scopus 로고    scopus 로고
    • Beta-blockers for primary prevention of heart failure in patients with hypertension insights from a meta-analysis
    • Bangalore S, Wild D, Parkar S, et al. Beta-blockers for primary prevention of heart failure in patients with hypertension insights from a meta-analysis. J Am Coll Cardiol 2008;52:1062-72
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1062-1072
    • Bangalore, S.1    Wild, D.2    Parkar, S.3
  • 33
    • 47649085694 scopus 로고    scopus 로고
    • Risk/benefit assessment of beta-blockers and diuretics precludes their use for first-line therapy in hypertension
    • Messerli FH, Bangalore S, Julius S. Risk/benefit assessment of beta-blockers and diuretics precludes their use for first-line therapy in hypertension. Circulation 2008;117:2706-15
    • (2008) Circulation , vol.117 , pp. 2706-2715
    • Messerli, F.H.1    Bangalore, S.2    Julius, S.3
  • 36
    • 74249103427 scopus 로고    scopus 로고
    • The safety profile of telmisartan as monotherapy or combined with hydrochlorothiazide: A retrospective analysis of 50 studies
    • Schumacher H, Mancia G. The safety profile of telmisartan as monotherapy or combined with hydrochlorothiazide: a retrospective analysis of 50 studies. Blood Press 2008;17(Suppl 1):32-40
    • (2008) Blood Press , vol.17 , Issue.SUPPL. 1 , pp. 32-40
    • Schumacher, H.1    Mancia, G.2
  • 37
    • 40449097623 scopus 로고    scopus 로고
    • Discontinuation of and changes in drug therapy for hypertension among newly-treated patients: A population-based study in Italy
    • DOI 10.1097/HJH.0b013e3282f4edd7, PII 0000487220080400000030
    • Corrao G, Zambon A, Parodi A, et al. Discontinuation of and changes in drug therapy for hypertension among newly-treated patients: a population-based study in Italy. J Hypertens 2008;26:819-24 (Pubitemid 351354932)
    • (2008) Journal of Hypertension , vol.26 , Issue.4 , pp. 819-824
    • Corrao, G.1    Zambon, A.2    Parodi, A.3    Poluzzi, E.4    Baldi, I.5    Merlino, L.6    Cesana, G.7    Mancia, G.8
  • 38
    • 44949104716 scopus 로고    scopus 로고
    • Comparison of angiotensin II type 1 receptor antagonists in the treatment of essential hypertension
    • DOI 10.2165/00003495-200868090-00003
    • Smith DH. Comparison of angiotensin II type 1 receptor antagonists in the treatment of essential hypertension. Drugs 2008;68(9):1207-25 (Pubitemid 351822111)
    • (2008) Drugs , vol.68 , Issue.9 , pp. 1207-1225
    • Smith, D.H.G.1
  • 39
    • 78049441837 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitor associated cough: Deceptive information from the Physicians' Desk Reference
    • Bangalore S, Kumar S, Messerli FH. Angiotensin-converting enzyme inhibitor associated cough: deceptive information from the Physicians' Desk Reference. Am J Med 2010;123:1016-30
    • (2010) Am J Med , vol.123 , pp. 1016-1030
    • Bangalore, S.1    Kumar, S.2    Messerli, F.H.3
  • 40
    • 79955522788 scopus 로고    scopus 로고
    • Meta-analysis: Impact of drug class on adherence to antihypertensives
    • Kronish IM, Woodward M, Sergie Z, et al. Meta-analysis: impact of drug class on adherence to antihypertensives. Circulation 2011;123:1611-21
    • (2011) Circulation , vol.123 , pp. 1611-1621
    • Kronish, I.M.1    Woodward, M.2    Sergie, Z.3
  • 41
    • 0037490085 scopus 로고    scopus 로고
    • Value of low dose combination treatment with blood pressure lowering drugs: Analysis of 354 randomised trials
    • Law MR, Wald NJ, Morris JK, Jordan RE. Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials. BMJ 2003;326:1427
    • (2003) BMJ , vol.326 , pp. 1427
    • Law, M.R.1    Wald, N.J.2    Morris, J.K.3    Jordan, R.E.4
  • 42
    • 77952106918 scopus 로고    scopus 로고
    • ASH position article: Combination therapy in hypertension
    • Gradman AH, Basile JN, Carter BL, et al. ASH position article: combination therapy in hypertension. J Am Soc Hypertens 2010;4:90-8
    • (2010) J Am Soc Hypertens , vol.4 , pp. 90-98
    • Gradman, A.H.1    Basile, J.N.2    Carter, B.L.3
  • 43
    • 70449851433 scopus 로고    scopus 로고
    • Reappraisal of European guidelines on hypertension management: A European Society of Hypertension Task Force document
    • Mancia G, Laurent S, Agabiti-Rosei E, et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J Hypertens 2009;27:2121-58
    • (2009) J Hypertens , vol.27 , pp. 2121-2158
    • Mancia, G.1    Laurent, S.2    Agabiti-Rosei, E.3
  • 44
    • 78149263066 scopus 로고    scopus 로고
    • Management of high blood pressure in blacks. An update of the International society on hypertension in blacks consensus statement
    • Flack JM, Sica DA, Bakris G, et al. Management of High Blood Pressure in Blacks. An update of the International society on hypertension in blacks consensus statement. Hypertension 2010;56:780-800
    • (2010) Hypertension , vol.56 , pp. 780-800
    • Flack, J.M.1    Sica, D.A.2    Bakris, G.3
  • 45
    • 65449181110 scopus 로고    scopus 로고
    • Results of treatment with telmisartan-amlodipine in hypertensive patients
    • Littlejohn TW III, Majul CR, Olvera R, et al. Results of treatment with telmisartan-amlodipine in hypertensive patients. J Clin Hypertens (Greenwich) 2009;11:207-13
    • (2009) J Clin Hypertens (Greenwich) , vol.11 , pp. 207-213
    • Littlejohn Iii, T.W.1    Majul, C.R.2    Olvera, R.3
  • 46
    • 64849092873 scopus 로고    scopus 로고
    • Telmisartan plus amlodipine in patients with moderate or severe hypertension: Results from a subgroup analysis of a randomized, placebo-controlled, parallel-group, 4 - 4 factorial study
    • Littlejohn TW III, Majul CR, Olvera R, et al. Telmisartan plus amlodipine in patients with moderate or severe hypertension: results from a subgroup analysis of a randomized, placebo-controlled, parallel-group, 4 - 4 factorial study. Postgrad Med 2009;121:5-14
    • (2009) Postgrad Med , vol.121 , pp. 5-14
    • Littlejohn Iii, T.W.1    Majul, C.R.2    Olvera, R.3
  • 47
    • 43549100189 scopus 로고    scopus 로고
    • The combination of olmesartan medoxomil and amlodipine besylate in controlling high blood pressure: COACH, a randomized, double-blind, placebo-controlled, 8-week factorial efficacy and safety study
    • DOI 10.1016/j.clinthera.2008.04.002, PII S0149291808001410
    • Chrysant SG, Melino M, Karki S, et al. The combination of olmesartan medoxomil and amlodipine besylate in controlling high blood pressure: COACH, a randomized, double-blind, placebo-controlled, 8-week factorial efficacy and safety study. Clin Ther 2008;30:587-604 (Pubitemid 351680489)
    • (2008) Clinical Therapeutics , vol.30 , Issue.4 , pp. 587-604
    • Chrysant, S.G.1    Melino, M.2    Karki, S.3    Lee, J.4    Heyrman, R.5
  • 48
    • 34447109035 scopus 로고    scopus 로고
    • Two multicenter, 8-week, randomized, double-blind, placebo-controlled, parallel-group studies evaluating the efficacy and tolerability of amlodipine and valsartan in combination and as monotherapy in adult patients with mild to moderate essential hypertension
    • DOI 10.1016/j.clinthera.2007.03.018, PII S0149291807001002
    • Philipp T, Smith TR, Glazer R, et al. Two multicenter, 8-week, randomized, double-blind, placebo-controlled, parallel-group studies evaluating the efficacy and tolerability of amlodipine and valsartan in combination and as monotherapy in adult patients with mild to moderate essential hypertension. Clin Ther 2007;29:563-80 (Pubitemid 47028551)
    • (2007) Clinical Therapeutics , vol.29 , Issue.4 , pp. 563-580
    • Philipp, T.1    Smith, T.R.2    Glazer, R.3    Wernsing, M.4    Yen, J.5    Jin, J.6    Schneider, H.7    Pospiech, R.8
  • 49
    • 34547688084 scopus 로고    scopus 로고
    • Effects of monotherapy and combination therapy on blood pressure control and target organ damage: A randomized prospective intervention study in a large population of hypertensive patients
    • Tedesco MA, Natale F, Calabro R. Effects of monotherapy and combination therapy on blood pressure control and target organ damage: a randomized prospective intervention study in a large population of hypertensive patients. J Clin Hypertens 2006;8:634-41
    • (2006) J Clin Hypertens , vol.8 , pp. 634-641
    • Tedesco, M.A.1    Natale, F.2    Calabro, R.3
  • 50
    • 61649091385 scopus 로고    scopus 로고
    • Combination therapy versus monotherapy in reducing blood pressure: Meta-analysis on 11,000 participants from 42 trials
    • Wald DS, Law M, Morris JK, et al. Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials. Am J Med 2009;122:290-300
    • (2009) Am J Med , vol.122 , pp. 290-300
    • Wald, D.S.1    Law, M.2    Morris, J.K.3
  • 51
    • 77954957139 scopus 로고    scopus 로고
    • Effects of telmisartan and amlodipine in combination on ambulatory blood pressure in stages 1-2 hypertension
    • White WB, Littlejohn TW, Majul CR, et al. Effects of telmisartan and amlodipine in combination on ambulatory blood pressure in stages 1-2 hypertension. Blood Press Monit 2010;15:205-12
    • (2010) Blood Press Monit , vol.15 , pp. 205-212
    • White, W.B.1    Littlejohn, T.W.2    Majul, C.R.3
  • 52
    • 84856288077 scopus 로고    scopus 로고
    • Available from: Accessed August
    • NICE Guidelines. Available from: http://guidance.nice.org.uk/CG127 [Accessed August 2011
    • (2011)
  • 53
    • 79551664955 scopus 로고    scopus 로고
    • Effect of renin-angiotensin system blockade on calcium channel blocker-associated peripheral edema
    • Makani H, Bangalore S, Romero J, et al. Effect of renin-angiotensin system blockade on calcium channel blocker-associated peripheral edema. Am J Med 2011;124:128-35
    • (2011) Am J Med , vol.124 , pp. 128-135
    • Makani, H.1    Bangalore, S.2    Romero, J.3
  • 54
    • 34250157719 scopus 로고    scopus 로고
    • Effect on the development of ankle edema of adding delapril to manidipine in patients with mild to moderate essential hypertension: A three-way crossover study
    • DOI 10.1016/S0149-2918(07)80079-8, PII S0149291807800798
    • Fogari R, Malamani G, Zoppi A, et al. Effect on the development of ankle edema of adding delapril to manidipine in patients with mild to moderate essential hypertension: a three-way crossover study. Clin Ther 2007;29:413-18 (Pubitemid 46907281)
    • (2007) Clinical Therapeutics , vol.29 , Issue.3 , pp. 413-418
    • Fogari, R.1    Malamani, G.2    Zoppi, A.3    Mugellini, A.4    Rinaldi, A.5    Fogari, E.6    Perrone, T.7
  • 55
    • 33847044811 scopus 로고    scopus 로고
    • Effect of valsartan addition to amlodipine on ankle oedema and subcutaneous tissue pressure in hypertensive patients
    • Fogari R, Zoppi A, Derosa G, et al. Effect of valsartan addition to amlodipine on ankle oedema and subcutaneous tissue pressure in hypertensive patients. J Hum Hypertens 2007;21:220-4
    • (2007) J Hum Hypertens , vol.21 , pp. 220-224
    • Fogari, R.1    Zoppi, A.2    Derosa, G.3
  • 56
    • 80054076692 scopus 로고    scopus 로고
    • Effect of telmisartan addition to amlodipine on ankle edema development in treating hypertensive patients
    • Fogari R, Zoppi A, Maffioli P, Lazzari P. Effect of telmisartan addition to amlodipine on ankle edema development in treating hypertensive patients. Expert Opin Pharmacother 2011;12(16):2441-8
    • (2011) Expert Opin Pharmacother , vol.12 , Issue.16 , pp. 2441-2448
    • Fogari, R.1    Zoppi, A.2    Maffioli, P.3    Lazzari, P.4
  • 57
    • 34250179723 scopus 로고    scopus 로고
    • Fixed-Dose Combinations Improve Medication Compliance: A Meta-Analysis
    • DOI 10.1016/j.amjmed.2006.08.033, PII S000293430601151X
    • Bangalore S, Kamalakkannan G, Parkar S, Messerli FH. Fixed-dose combinations improve medication compliance: a meta-analysis. Am J Med 2007;120:713-19 (Pubitemid 47176510)
    • (2007) American Journal of Medicine , vol.120 , Issue.8 , pp. 713-719
    • Bangalore, S.1    Kamalakkannan, G.2    Parkar, S.3    Messerli, F.H.4
  • 58
    • 39749117949 scopus 로고    scopus 로고
    • Compliance with antihypertensive therapy in the elderly
    • Dickson M, Plauschinat CA. Compliance with antihypertensive therapy in the elderly. Am J Cardiovasc Drugs 2008;8:45-50
    • (2008) Am J Cardiovasc Drugs , vol.8 , pp. 45-50
    • Dickson, M.1    Plauschinat, C.A.2
  • 59
    • 34547636649 scopus 로고    scopus 로고
    • Adherence patterns among patients treated with fixed-dose combination versus separate antihypertensive agents
    • DOI 10.2146/ajhp060434
    • Gerbino PP, Shoheiber O. Adherence patterns among patients treated with fixed-dose combination versus separate antihypertensive agents. Am J Health Syst Pharm 2007;64:1279-83 (Pubitemid 47216196)
    • (2007) American Journal of Health-System Pharmacy , vol.64 , Issue.12 , pp. 1279-1283
    • Gerbino, P.P.1    Shoheiber, O.2
  • 60
    • 78349260029 scopus 로고    scopus 로고
    • Adherence and persistence of single-pill ARB/CCB combination therapy compared to multiple-pill ARB/CCB regimens
    • Zeng F, Patel BV, Andrews L, et al. Adherence and persistence of single-pill ARB/CCB combination therapy compared to multiple-pill ARB/CCB regimens. Curr Med Res Opin 2010;26:2877-87
    • (2010) Curr Med Res Opin , vol.26 , pp. 2877-2887
    • Zeng, F.1    Patel, B.V.2    Andrews, L.3
  • 61
    • 77149134656 scopus 로고    scopus 로고
    • The role of fixed-dose combination therapy with drugs that target the renin-angiotensin system in the hypertension paradigm
    • Schmieder RE. The role of fixed-dose combination therapy with drugs that target the renin-angiotensin system in the hypertension paradigm. Clin Exp Hypertens 2010;32:35-42
    • (2010) Clin Exp Hypertens , vol.32 , pp. 35-42
    • Schmieder, R.E.1
  • 62
    • 77957314718 scopus 로고    scopus 로고
    • The role of angiotensin receptor blocker and calcium channel blocker combination therapy in treating hypertension: Focus on recent studies
    • Chrysant SG. The role of angiotensin receptor blocker and calcium channel blocker combination therapy in treating hypertension: focus on recent studies. Am J Cardiovasc Drugs 2010;10:315-20
    • (2010) Am J Cardiovasc Drugs , vol.10 , pp. 315-320
    • Chrysant, S.G.1
  • 63
    • 79959663642 scopus 로고    scopus 로고
    • Telmisartan and amlodipine single-pill combinations versus amlodipine monotherapy for superior blood pressure lowering and improved tolerability in patients with uncontrolled hypertension: Results of the TEAMSTA-5 study
    • on behalf of the TEAMSTA-5 Investigators
    • Neldam S, Lang M, Jones R, on behalf of the TEAMSTA-5 Investigators. Telmisartan and amlodipine single-pill combinations versus amlodipine monotherapy for superior blood pressure lowering and improved tolerability in patients with uncontrolled hypertension: results of the TEAMSTA-5 study. J Clin Hypertens 2011;13(7):459-66
    • (2011) J Clin Hypertens , vol.13 , Issue.7 , pp. 459-466
    • Neldam, S.1    Lang, M.2    Jones, R.3
  • 64
    • 81155128881 scopus 로고    scopus 로고
    • Long-term efficacy and safety profile of single-pill combinations of telmisartan/amlodipine in patients not controlled on amlodipine 10 mg: Open-label follow-up of teamsta-10: Pp.27.90
    • on behalf of the TEAMSTA-10 Investigators
    • Neldam S, Edwards C, Jones R, on behalf of the TEAMSTA-10 Investigators. Long-term efficacy and safety profile of single-pill combinations of telmisartan/amlodipine in patients not controlled on amlodipine 10 mg: open-label follow-up of teamsta-10: Pp.27.90. J Hypertens 2010;28:e474
    • (2010) J Hypertens , vol.28
    • Neldam, S.1    Edwards, C.2    Jones, R.3
  • 65
    • 84856252318 scopus 로고    scopus 로고
    • Efficacy of telmisartan in combination with amlodipine in obese hypertensive patients: Sub-analysis from a factorial design study
    • Littlejohn, TW III, Chrysant SG, Webster D, et al. Efficacy of telmisartan in combination with amlodipine in obese hypertensive patients: sub-analysis from a factorial design study. J Clin Hypertens 2009;11(Suppl A):A158
    • (2009) J Clin Hypertens , vol.11 , Issue.SUPPL. A
    • Littlejohn Iii, T.W.1    Chrysant, S.G.2    Webster, D.3
  • 66
    • 78649368537 scopus 로고    scopus 로고
    • Telmisartan in combination with amlodipine provides a highly effective and well tolerated treatment option for hypertensive patients with diabetes: Sub-analysis from a factorial design study
    • Littlejohn T, Ruilope LM, Raskin P, et al. Telmisartan in combination with amlodipine provides a highly effective and well tolerated treatment option for hypertensive patients with diabetes: sub-analysis from a factorial design study. J Hypertens 2009;27(Suppl 4);S275
    • (2009) J Hypertens , vol.27 , Issue.SUPPL. 4
    • Littlejohn, T.1    Ruilope, L.M.2    Raskin, P.3
  • 67
    • 77958061226 scopus 로고    scopus 로고
    • Efficacy and tolerability of amlodipine plus olmesartan medoxomil in patients with difficult-to-treat hypertension
    • Chrysant SG, Lee J, Melino M, et al. Efficacy and tolerability of amlodipine plus olmesartan medoxomil in patients with difficult-to-treat hypertension. J Hum Hypertens 2010;24:730-8
    • (2010) J Hum Hypertens , vol.24 , pp. 730-738
    • Chrysant, S.G.1    Lee, J.2    Melino, M.3
  • 68
    • 79960385068 scopus 로고    scopus 로고
    • Single-pill combination of telmisartan 80 mg/amlodipine 10 mg provides superior blood pressure reductions in patients with severe hypertension: TEAMSTA Severe HTN Study [abstract]
    • Neutel JM, Mancia G, Black HR, et al. Single-pill combination of telmisartan 80 mg/amlodipine 10 mg provides superior blood pressure reductions in patients with severe hypertension: TEAMSTA Severe HTN Study [abstract]. J Clin Hypertens 2010;12(Suppl7):537
    • (2010) J Clin Hypertens , vol.12 , Issue.SUPPL. 7 , pp. 537
    • Neutel, J.M.1    Mancia, G.2    Black, H.R.3
  • 70
    • 57349138291 scopus 로고    scopus 로고
    • ACCOMPLISH trial investigators. Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients
    • Jamerson K, Weber MA, Bakris GL, et al. ACCOMPLISH Trial Investigators. Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. N Engl J Med 2008;359:2417-28
    • (2008) N Engl J Med , vol.359 , pp. 2417-2428
    • Jamerson, K.1    Weber, M.A.2    Bakris, G.L.3
  • 71
    • 77950187294 scopus 로고    scopus 로고
    • Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): A prespecified secondary analysis of a randomised controlled trial
    • Bakris GL, Sarafidis PA, Weir MR, et al. Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial. Lancet 2010;375:1173-81
    • (2010) Lancet , vol.375 , pp. 1173-1181
    • Bakris, G.L.1    Sarafidis, P.A.2    Weir, M.R.3


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