The combination of olmesartan medoxomil and amlodipine besylate in controlling high blood pressure: COACH, a randomized, double-blind, placebo-controlled, 8-week factorial efficacy and safety study

Clinical Therapeutics

Volumn 30, Issue 4, 2008, Pages 587-604

  Chrysant, Steven G ^a   Melino, Michael ^b   Karki, Sulekha ^b   Lee, James ^b   Heyrman, Reinilde ^b  

^a Oklahoma Cardiovascular and Hypertension Center   (United States)

^b DAIICHI SANKYO INC   (United States)

Author keywords

amlodipine besylate; edema; fixed dose combination; hypertension; olmesartan medoxomil

Indexed keywords

AMLODIPINE BESYLATE; OLMESARTAN; PLACEBO;

ADULT; ANTIHYPERTENSIVE THERAPY; ARTICLE; BLOOD PRESSURE MONITORING; BLOOD PRESSURE REGULATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE CLASSIFICATION; DIZZINESS; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; EDEMA; FATIGUE; FEMALE; HEADACHE; HUMAN; HYPERTENSION; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; MULTICENTER STUDY; NAUSEA; RANDOMIZED CONTROLLED TRIAL; RASH; SEAT; STATISTICAL SIGNIFICANCE; SYSTOLIC BLOOD PRESSURE;

AGED; AMLODIPINE; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; BLOOD PRESSURE; BLOOD PRESSURE MONITORING, AMBULATORY; CALCIUM CHANNEL BLOCKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERTENSION; IMIDAZOLES; MALE; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; TETRAZOLES; TREATMENT OUTCOME;

EID: 43549100189     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2008.04.002     Document Type: Article

References (36)