A pseudo MS 3 approach for identification of disulfide-bonded proteins: Uncommon product ions and database search

Journal of the American Society for Mass Spectrometry

Volumn 23, Issue 2, 2012, Pages 225-243

  Chen, Jianzhong ^a,b   Shiyanov, Pavel ^a   Schlager, John J ^a   Green, Kari B ^b  

^a AIR FORCE RESEARCH LABORATORY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Arginine residue; Aspartic acid residue; b+H2O ion; Bond rearrangement; c ion; Collision induced dissociation; Cysteine residue; d ion; Database search; Disulfide bond cleavage; Electrospray ionization; HN=C=NH; Intact protein; Lysine residue; Lysozyme; Mobile proton; MS MS; MS3; Neutral loss; Nozzle skimmer dissociation; Oxazolone structure; ProteinProspector; Quadrupole time of flight; Salt bridge; Sequence scrambling; six membered ring; Sodiated ion; Top down; Uncommon product ions

Indexed keywords

ARGININE RESIDUE; ASPARTIC ACID RESIDUE; BOND REARRANGEMENT; COLLISION-INDUCED DISSOCIATION; CYSTEINE RESIDUES; DATABASE SEARCHES; DISULFIDE BONDS; ELECTROSPRAYS; HN=C=NH; INTACT PROTEINS; LYSINE RESIDUES; LYSOZYME; MOBILE PROTONS; MS/MS; MS3; NEUTRAL LOSS; NOZZLE-SKIMMER DISSOCIATIONS; PROTEINPROSPECTOR; QUADRUPOLES; SALT BRIDGE; SEQUENCE SCRAMBLING; SIX-MEMBERED RINGS; TOPDOWN;

ANIMALS; ARGININE; COVALENT BONDS; DATABASE SYSTEMS; DISSOCIATION; ELECTROSPRAY IONIZATION; ENZYMES; INFORMATION RETRIEVAL; IONIZATION; MASS SPECTROMETRY; NOZZLES; ORGANIC ACIDS; POSITIVE IONS; PROTONS; SEARCH ENGINES;

PROTEINS;

ARGININE; ASPARTIC ACID; DEHYDROALANINE; LYSINE; LYSOZYME; DISULFIDE; ION; PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; COLLISIONALLY ACTIVATED DISSOCIATION; COMPUTER PROGRAM; DATA BASE; DISSOCIATION; DISULFIDE BOND; MASS SPECTROMETER; NOZZLE SKIMMER DISSOCIATION; PROTEIN ANALYSIS; PROTEIN PROCESSING; PROTEIN STRUCTURE; PROTON TRANSPORT; QUADRUPOLE MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CHICKEN; METHODOLOGY; MOLECULAR GENETICS; PROTEIN DATABASE; TANDEM MASS SPECTROMETRY;

GALLUS GALLUS;

AMINO ACID SEQUENCE; ANIMALS; CHICKENS; DATABASES, PROTEIN; DISULFIDES; IONS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MURAMIDASE; PROTEINS; TANDEM MASS SPECTROMETRY;

EID: 84856284421     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-011-0294-6     Document Type: Article

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