Herbal formula HMC05 prevents human aortic smooth muscle cell migration and proliferation by inhibiting the ERK1/2 MAPK signaling cascade

Journal of Natural Medicines

Volumn 66, Issue 1, 2012, Pages 177-184

  Kang, Yun Hwan ^a   Yang, In Jun ^a   Shin, Heung Mook ^a  

^a Dongguk University   (South Korea)

Author keywords

HASMC migration and proliferation; HMC05; Human aortic smooth muscle cells; MAPK signal pathway; Tumor necrosis factor

Indexed keywords

GELATINASE B; HERBACEOUS AGENT; HMC 05; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; S6 KINASE; TRANSCRIPTION FACTOR ELK 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; TUMOR NECROSIS FACTOR ALPHA RECEPTOR 1; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

AORTA MEDIA; ARTICLE; CELL ASSAY; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; MMP9 GENE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

AORTA; BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ETS-DOMAIN PROTEIN ELK-1; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PLANT EXTRACTS; PROTEIN KINASE INHIBITORS; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84856235491     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-011-0573-3     Document Type: Article

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