Simultaneous determination of alkaloids and flavonoids in HMC05 preparation by HPLC-DAD

Journal of Liquid Chromatography and Related Technologies

Volumn 31, Issue 19, 2008, Pages 2917-2926

  Kim, Seung Hyun ^a   Choi, Eun Jung ^a   Lee, Ki Yong ^b   Sung, Sang Hyun ^b   Shin, Heung Mook ^c  

^a Elcom Science Co Ltd   (South Korea)

^b Seoul National University   (South Korea)

^c Dongguk University   (South Korea)

Author keywords

HMC05; HPLC DAD; Simultaneous determination; Validation

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; HIGH PRESSURE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SOLVENT EXTRACTION; SULFONATION;

HMC05; HPLC-DAD; SIMULTANEOUS DETERMINATION; VALIDATION;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ALKALOID DERIVATIVE; ATRACTYLODES MACROCEPHALA EXTRACT; BERBERINE; COPTISINE; FLAVONOID; HESPERIDIN; PALMATINE; PLANT EXTRACT; PORIA COCOS EXTRACT;

ARTICLE; COPTIDIS JAPONICA; CRATAEGUS PINNATIFIDA; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG SCREENING; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; GASTRODIA ELATA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY DIODE ARRAY DETECTION; INSTRUMENTATION; MEDICINAL PLANT; PINELLA TERNATE; QUANTITATIVE ANALYSIS; SATSUMA; SENSITIVITY AND SPECIFICITY; SIEGESBECKIA PUBESCENS; TECHNIQUE; VALIDATION PROCESS;

EID: 53249113452     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070802424501     Document Type: Article

References (10)

1. Balunas, M.J.; Kinghorn, A.D. Drug discovery from medicinal plants. Life Sci. 2005, 78, 431-441.
2. Liang, Y.Z.; Xie, P.; Chan, K. Quality control of herbal medicines. J. Chromatogr. B 2004, 812, 53-70.
3. Kim, K.M.; Choi, J.Y.; Yoo, S.E.; Park, M.Y.; Lee, B.S.; Ko, Y.H.; Sung, S.H.; Shin, H.M.; Park, J.E. HMC05, herbal extract, inhibits NF-κB expression in lipopolysaccharide treated macrophages and reduces atherosclerotic lesions in cholesterol fed mice. J. Ethnopharmacol. 2007, 114, 316-324.
4. Shin, H.M.; Morgan, K.G. Vasodilation by banhabackchulchunmatang, a Chinese medicine, is associated with negative modulation of PKCalpa activation and NO production. Life Sci. 2003, 74, 723-732.
5. Chen, P.; Li, C.; Liang, S.; Song, G.; Sun, Y.; Shi, Y.; Xu, S.; Zjang, J.; Sheng, S.; Yang, Y.; Li, M. Characterization and quantification of eight water-soluble constituents in tubers of Pinellia ternate and in tea granules from the Chinese multi-herb remedy Xiaochaihu-tang. J. Chromatogr. B 2006, 843, 183-193.
6. Zhao, Y.; Cao, Q.; Xiang, Y.; Hu, Z. Identification and determination of active components in Gastrodia elata Bl. by capillary electrolysis. J. Chromatogr. A 1999, 849, 277-283.
7. Nogata, Y.; Ohta, H.; Yoza, K.I.; Berhow, M.; Hasegawa, S. High-performance liquid chromatographic determination of naturally occurring flavonoid in Citus with a photodiode array dectector. J. Chromatogr. A 1994, 667, 59-66.
8. Cui, H.; He, C.; Zhao, G.W. Determination of polyphenols by high-performance liquid chromatography with inhibited chemiluminescence detection. J. Chromatogr. A 1999, 855, 171-179.
9. Su, X.Z.; Kong, L.; Li, X.; Chen, X.; Guo, M.; Zou, H. Screening and analysis of bioactive compounds with biofingerprinting chromatogram analysis of traditional Chinese medicines targeting DNA by microdialysis/HPLC. J. Chromatogr. A 2005, 1076, 118-126.
10. Yu, S.; Pang, X.; Deng, Y.; Li, L.; Liang, Y.; Liu, X.; Xie, L.; Wang, G.; Wang, X. A sensitive and specific liquid chromatography mass spectrometry method for simultaneous determination of berberine, palmatine, coptisine, epiberberine and jatrorrhizine from Coptidis Rhizoma in rat plasma. Int. J. Mass Spectrom. 2007, 268, 30-37.