Trimethylsilyldiazomethane derivatization coupled with solid-phase extraction for the determination of alendronate in human plasma by LC-MS/MS

Analytical and Bioanalytical Chemistry

Volumn 402, Issue 2, 2012, Pages 791-798

  Chen, Meixia ^a   Liu, Ke ^a   Zhong, Dafang ^a   Chen, Xiaoyan ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Alendronate; Derivatization; LC MS MS; Pharmacokinetics; Trimethylsilyldiazomethane

Indexed keywords

ALENDRONATE; ANALYTES; ANION EXCHANGE; BIOANALYSIS; BISPHOSPHONATES; CALIBRATION CURVES; CHROMATOGRAPHIC SEPARATIONS; DERIVATIZATIONS; HUMAN PLASMAS; INTER-ASSAY PRECISION; INTERNAL STANDARDS; LC-MS/MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LOWER LIMIT OF QUANTIFICATIONS; ONE STEP; PHARMACOKINETIC PROFILES; POLAR COMPOUNDS; PRECOLUMN DERIVATIZATIONS; RUNTIMES; SOLID-PHASE; SOLID-PHASE EXTRACTION; TRIMETHYLSILYLDIAZOMETHANE; VALIDATED METHODS;

CHROMOPHORES; COLUMN CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHANOL; PHARMACOKINETICS; PHASE SEPARATION; PLASMA (HUMAN); SODIUM;

EXTRACTION;

ALENDRONIC ACID; DIAZOMETHANE; DRUG DERIVATIVE; TRIMETHYLSILYL DERIVATIVE; TRIMETHYLSILYLDIAZOMETHANE;

ARTICLE; BLOOD; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

ALENDRONATE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIAZOMETHANE; HUMANS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; TRIMETHYLSILYL COMPOUNDS;

EID: 84856233287     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-011-5467-4     Document Type: Article

References (25)

1. D Hosking CE Chilvers C Christiansen P Ravn R Wasnich P Ross M McClung A Balske D Thompson M Daley AJ Yates 1998 Prevention of bone loss with alendronate in postmenopausal women under 60 years of age N Engl J Med 338 8 485 492 10.1056/NEJM199802193380801 1:CAS:528:DyaK1cXhsVGju70%3D (Pubitemid 28103131)
2. RG Russell MJ Rogers 1999 Bisphosphonates: from the laboratory to the clinic and back again Bone 25 1 97 106 10.1016/S8756-3282(99)00116-7 1:CAS:528:DyaK1MXkvV2ru70%3D (Pubitemid 29322070)
3. JS Finkelstein JJ Wyland H Lee RM Neer 2010 Effects of teriparatide, alendronate, or both in women with postmenopausal osteoporosis J Clin Endocrinol Metab 95 1838 1845 10.1210/jc.2009-1703 1:CAS:528:DC%2BC3cXltFSnsL8%3D
4. H Fleisch 2003 Bisphosphonates in osteoporosis Eur Spine J 12 Suppl 2 S142 S146 10.1007/s00586-003-0622-z (Pubitemid 37409931)
5. CK Zacharis PD Tzanavaras 2008 Determination of bisphosphonate active pharmaceutical ingredients in pharmaceuticals and biological material: a review of analytical methods J Pharm Biomed 48 483 496 10.1016/j.jpba.2008.05.028 1:CAS:528:DC%2BD1cXht1yms7nN
6. Z Xie Y Jiang D Zhang 2006 Simple analysis of four bisphosphonates simultaneously by reverse phase liquid chromatography using n-amylamine as volatile ion-pairing agent J Chromatogr A 1104 173 178 10.1016/j.chroma.2005.11. 113 1:CAS:528:DC%2BD28XmsVKrtQ%3D%3D (Pubitemid 43099889)
7. EW Tsai DP Ip MA Brooks 1992 Determination of alendronate in pharmaceutical dosage formulations by ion chromatography with conductivity detection J Chromatogr A 596 2 217 224 10.1016/0021-9673(92)85010-Q 1:CAS:528:DyaK38XktFCnu7k%3D
8. X Qin EW Tsai T Sakuma DP Ip 1994 Pharmaceutical application of liquid chromatography-mass spectrometry: II. Ion chromatography-ion spray mass spectrometric characterization of alendronate J Chromatogr A 686 2 205 212 10.1016/0021-9673(94)00798-5 1:CAS:528:DyaK2MXitlahsbc%3D
9. YR Han X Qin 1996 Determination of alendronate sodium by ion chromatography with refractive index detection J Chromatogr A 719 345 352 10.1016/0021-9673(95)00728-8 1:CAS:528:DyaK28XlvVOlsg%3D%3D (Pubitemid 26032071)
10. WF Kline BK Matuszewski 1992 Improved determination of the bisphosphonate alendronate in human plasma and urine by automated precolumn derivatization and high-performance liquid chromatography with fluorescence and electrochemical detection J Chromatogr 583 2 183 193 10.1016/0378-4347(92)80551-Z 1:CAS:528:DyaK3sXhtFKitr4%3D
11. P Ptáček J Klíma J Macek 2002 Determination of alendronate in human urine as 9-fluorenylmethyl derivative by high-performance liquid chromatography J Chromatogr B 767 1 111 116 10.1016/S0378-4347(01)00551-5 (Pubitemid 34142342)
12. H Kang S Hwang J Park C Kim 2006 HPLC method validation and pharmacokinetic study of alendronate sodium in human urine with fluorescence detection J Liq Chromatogr R T 29 1589 1600 10.1080/10826070600678308 1:CAS:528:DC%2BD28XktVyntbs%3D
13. C Apostolou Y Dotsikas C Kousoulos G Tsatsou F Colocouri GS Soumelas YL Loukas 2007 Application of a semi-automated 96-well format solid-phase extraction, column-switching, fluorescence detection protocol for the determination of alendronate in human urine samples obtained from a bioequivalence study J Pharm Biomed 43 1151 1155 10.1016/j.jpba.2006.09.012 1:CAS:528:DC%2BD2sXht1OltLs%3D (Pubitemid 46201744)
14. MH Yun KI Kwon 2006 High-performance liquid chromatography method for determining alendronate sodium in human plasma by detecting fluorescence: application to a pharmacokinetic study in humans J Pharm Biomed Anal 40 1 168 172 10.1016/j.jpba.2005.06.025 1:CAS:528:DC%2BD28XksFCitQ%3D%3D (Pubitemid 43061233)
15. SK Al Deeb II Hamdan SM Najjar 2004 Spectroscopic and HPLC methods for the determination of alendronate in tablets and urine Talanta 64 695 702 10.1016/j.talanta.2004.03.044 1:CAS:528:DC%2BD2cXns12gsLs%3D
16. J Meng Q Meng L Zheng 2009 A simple and rapid high-performance liquid chromatography method for determination of alendronate sodium in beagle dog plasma with application to preclinical pharmacokinetic study Biomed Chromatogr 24 169 173
17. Y Jeong J Park G Jin J Park 2011 Spectrofluorimetric determination of alendronate by conjugation with the rhodamine B sulfonyl group Bull Korean Chem Soc 32 5 1 3
18. I Tarcomnicu L Silvestro SR Savu A Gherase C Dulea 2007 Development and application of a high-performance liquid chromatography-mass spectrometry method to determine alendronate in human urine J Chromatogr A 1160 21 33 10.1016/j.chroma.2007.04.020 1:CAS:528:DC%2BD2sXotVCht7s%3D (Pubitemid 47068467)
19. Tamim MK, Gagne J-F, Nadeau F, Tanguay M, Trabelsi F, Vallee M (2010) Quantitative determination of alendronate sodium in human plasma using a validated LC- MS/MS method : application to clinical pharmacokinetic studies. www.aapsj.org/abstracts/AM-2010/M1500.pdf
20. LS Zhu VN Lapko JW Lee YJ Basir C Kafonek R Olsen C Briscoe 2006 A general approach for the quantitative analysis of bisphosphonates in human serum and urine by high-performance liquid chromatography/tandem mass spectrometry Rapid Commun Mass Spectrom 20 3421 3426 10.1002/rcm.2755 1:CAS:528: DC%2BD28Xht1Grtr%2FJ (Pubitemid 44763942)
21. Lu Z, Diehl D, Mazzeo J, Oehrle SA, Mallet CR, Young MS, Chambers E (2008) Methods for separating and analyzing anionic compounds. Patent Application Publication US 2008/0169242 A1. http://www.freshpatents.com/Methods- for-separating-and-analyzing-anionic-compounds-dt20080717ptan20080169242.php
22. Preu M, Petz M Trimethylsilyldiazomethane as a methylation reagent for residue analysis-a safer and better alternative to diazomethane. www2.uni-wuppertal.de/fb9/lebensmittelchemie/Kan%20ERIV.pdf
23. Derivatization of carboxylic acids with diazomethane and trimethylsilyldiazomethane: convenient methods and artifacts. userpage.chemie.fu-berlin.de/~tlehmann/krebs/files-diazoalkanes.pdf
24. A Presser A Hüfner 2004 Trimethylsilyldiazomethane-a mild and efficient reagent for the methylation of carboxylic acids and alcohols in natural products Monatshefte für Chemie 135 8 1015 1022 10.1007/s00706-004-0188-4 1:CAS:528:DC%2BD2cXmtVCnsrs%3D (Pubitemid 39118835)
25. VS Mannur D Patel VS Mastiholimath G Shah 2011 Selection of buffers in LC-MS/MS: an overview Int J Pharm Sci Rev Res 6 1 34 37 1:CAS:528: DC%2BC3MXhtlyjt78%3D