Deoxycytidine kinase is overexpressed in poor outcome breast cancer and determines responsiveness to nucleoside analogs

Breast Cancer Research and Treatment

Volumn 131, Issue 3, 2012, Pages 809-818

  Geutjes, Ernst Jan ^a   Tian, Sun ^b   Roepman, Paul ^b   Bernards, René ^a,b  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b Agendia NV   (Netherlands)

Author keywords

Biomarker; Breast cancer; DCK; Gemcitabine; Nucleoside analogs

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ANTHRACYCLINE DERIVATIVE; DEOXYCYTIDINE KINASE; GEMCITABINE;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER PATIENT; CANCER PROGNOSIS; CONTROLLED STUDY; DCK GENE; HUMAN; HUMAN CELL; IN VITRO STUDY; MAJOR CLINICAL STUDY; ONCOGENE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENSITIVITY ANALYSIS;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; DEOXYCYTIDINE KINASE; DEOXYRIBONUCLEOSIDES; DRUG RESISTANCE, NEOPLASM; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION; GENE SILENCING; HUMANS; LUNG NEOPLASMS; MICE; PROGNOSIS; TRANSDUCTION, GENETIC; TREATMENT OUTCOME;

EID: 84856221213     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-011-1477-3     Document Type: Article

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