Memory T cells persisting in the brain following MCMV infection induce long-term microglial activation via interferon-γ

Journal of NeuroVirology

Volumn 17, Issue 5, 2011, Pages 424-437

  Mutnal, Manohar B ^a   Hu, Shuxian ^a   Little, Morgan R ^a   Lokensgard, James R ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Brain; MCMV; Microglia; T cells

Indexed keywords

GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TUMOR NECROSIS FACTOR ALPHA; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; BRAIN INFECTION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL ISOLATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMEGALOVIRUS INFECTION; EFFECTOR CELL; FEMALE; IMMUNOSTIMULATION; KNOCKOUT MOUSE; LYMPHOCYTE MIGRATION; LYMPHOCYTIC INFILTRATION; MEMORY T LYMPHOCYTE; MICROGLIA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; UPREGULATION; VIRUS REPLICATION; WILD TYPE;

ANIMALS; BRAIN; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOMEGALOVIRUS INFECTIONS; FEMALE; GENES, MHC CLASS II; IMMUNOLOGIC MEMORY; INTERFERON-GAMMA; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MICROGLIA; MUROMEGALOVIRUS; NEUTROPHILS; PHENOTYPE; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; VIRUS REPLICATION;

ANIMALIA; MAIZE CHLOROTIC MOTTLE VIRUS; MURID HERPESVIRUS 1; MUS;

EID: 84856169008     PISSN: 13550284     EISSN: 15382443     Source Type: Journal    
DOI: 10.1007/s13365-011-0042-5     Document Type: Article

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